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  1. Srikanta Murthy A, Azis N, Jasni J, Othman ML, Mohd Yousof MF, Talib MA
    PLoS One, 2020;15(10):e0240368.
    PMID: 33035254 DOI: 10.1371/journal.pone.0240368
    This study presents an investigation on the effect of shield placement for mitigation of transient voltage in a 33/11 kV, 30 MVA transformer due to Standard Switching Impulse (SSI) and Oscillating Switching Impulse (OSI) surges. Generally, the winding and insulation in transformers could experience severe voltage stress due to the external impulses i.e. switching events. Hence, it is important to examine the voltage stress and identify the mitigation action i.e. shield placements in order to reduce the adverse effect to the transformer windings. First, the resistances, inductances, and capacitances (RLC) were calculated for disc type transformer in order to develop the winding RLC equivalent circuit. The SSI and OSI transient voltage waveforms were applied to the High Voltage (HV) winding whereby the transient voltages were simulated for each disc. The resulting voltage stresses were mitigated through different configurations of electrostatic shield placements. The resonant oscillations generated due to switching surges were analysed through initial voltage distribution. The analyses on the transient voltages of the transformer winding and standard error of the slope (SEb) reveal that the location of shield placement has a significant effect on the resonant switching voltages. The increment of the shield number in the windings does not guarantee optimize mitigation of the resonant switching transient voltages. It is found that the voltage stress along the windings is linear once a floating shield is placed between the HV and Low Voltage (LV) windings of the disc-type transformer under the SSI and OSI waveforms. These findings could assist the manufacturers with appropriate technical basis for mitigation of the transformer winding against the external transient switching overvoltage surges.
  2. Srikanta Murthy A, Azis N, Jasni J, Othman ML, Mohd Yousof MF, Talib MA
    PLoS One, 2020;15(8):e0236409.
    PMID: 32853253 DOI: 10.1371/journal.pone.0236409
    This paper proposes an alternative approach to extract transformer's winding parameters of resistance (R), inductance (L), capacitance (C) and conductance (G) based on Finite Element Method (FEM). The capacitance and conductance were computed based on Fast Multiple Method (FMM) and Method of Moment (MoM) through quasi-electrostatics approach. The AC resistances and inductances were computed based on MoM through quasi-magnetostatics approach. Maxwell's equations were used to compute the DC resistances and inductances. Based on the FEM computed parameters, the frequency response of the winding was obtained through the Bode plot function. The simulated frequency response by FEM model was compared with the simulated frequency response based on the Multi-conductor Transmission Line (MTL) model and the measured frequency response of a 33/11 kV, 30 MVA transformer. The statistical indices such as Root Mean Square Error (RMSE) and Absolute Sum of Logarithmic Error (ASLE) were used to analyze the performance of the proposed FEM model. It is found that the simulated frequency response by FEM model is quite close to measured frequency response at low and mid frequency regions as compared to simulated frequency response by MTL model based on RMSE and ASLE analysis.
  3. Al-Barazanchi I, Hashim W, Ahmed Alkahtani A, Rasheed Abdulshaheed H, Muwafaq Gheni H, Murthy A, et al.
    Comput Intell Neurosci, 2022;2022:9879259.
    PMID: 36156952 DOI: 10.1155/2022/9879259
    As of late 2019, the COVID19 pandemic has been causing huge concern around the world. Such a pandemic posed serious threats to public safety, the well-being of healthcare workers, and the overall health of the population. If automation can be implemented in healthcare systems, patients could be better cared for and health industries could be less burdened. To combat such challenges, e-health requires apps and intelligent systems. Using WBAN sensors and networks, a doctor or medical professional can advise patients on the best course of action. Patients' fitness could be assessed using WBAN sensors without interfering with their daily activities. When designing a monitoring system, system performance reliability for competent healthcare is critical. Existing research has failed to create a large device capable of handling a large network or to improve WBAN topologies for fast transmitting and receiving patient data. As a result, in this research, we create a multisensor WBAN (MSWBAN) intelligent system for transmitting and receiving critical patient data. To gather information from all cluster nodes and send it to multisensor WBAN, a novel additive distance-threshold routing protocol (ADTRP) is proposed. In small networks where data are managed by the transmitting node and the best data route is determined, this protocol has less redundancy. An edge-cutting-based routing optimization (ES-EC-R ES-EC-RO) is used to find the best route. The Trouped blowfish MD5 (TB-MD5) algorithm is used to encrypt and decrypt data, and the encrypted data are stored in a cloud database for security. The performance metrics of our proposed model are compared to current techniques for the best results. End-to-end latency is 63 ms, packet delivery is 95%, security is 95.7%, and throughput is 9120 bps, according to the results. The purpose of this article is to encourage engineers and front-line workers to develop digital health systems for tracking and controlling virus outbreaks.
  4. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, et al.
    Autophagy, 2016;12(1):1-222.
    PMID: 26799652 DOI: 10.1080/15548627.2015.1100356
  5. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
    Autophagy, 2021 Jan;17(1):1-382.
    PMID: 33634751 DOI: 10.1080/15548627.2020.1797280
    In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
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