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  1. Thatte U, Hussain S, de Rosas-Valera M, Malik MA
    Value Health, 2009 Nov-Dec;12 Suppl 3:S18-25.
    PMID: 20586975 DOI: 10.1111/j.1524-4733.2009.00622.x
    This paper discusses national programs implemented in India, Pakistan, Malaysia, and Philippines to generate and apply evidence in making informed policy decisions on the approval, pricing, reimbursement and financing of medicines, diagnostics, and medical devices.
  2. Malik MA, Amjad AI, Aslam S, Fakhrou A
    Front Res Metr Anal, 2024;9:1486832.
    PMID: 39583913 DOI: 10.3389/frma.2024.1486832
    INTRODUCTION: The current study explored the influence of Chat Generative Pre-Trained Transformer (ChatGPT) on the concepts, parameters, policies, and practices of creativity and plagiarism in academic and research writing.

    METHODS: Data were collected from 10 researchers from 10 different countries (Australia, China, the UK, Brazil, Pakistan, Bangladesh, Iran, Nigeria, Trinidad and Tobago, and Turkiye) using semi-structured interviews. NVivo was employed for data analysis.

    RESULTS: Based on the responses, five themes about the influence of ChatGPT on academic and research writing were generated, i.e., opportunity, human assistance, thought-provoking, time-saving, and negative attitude. Although the researchers were mostly positive about it, some feared it would degrade their writing skills and lead to plagiarism. Many of them believed that ChatGPT would redefine the concepts, parameters, and practices of creativity and plagiarism.

    DISCUSSION: Creativity may no longer be restricted to the ability to write, but also to use ChatGPT or other large language models (LLMs) to write creatively. Some suggested that machine-generated text might be accepted as the new norm; however, using it without proper acknowledgment would be considered plagiarism. The researchers recommended allowing ChatGPT for academic and research writing; however, they strongly advised it to be regulated with limited use and proper acknowledgment.

  3. Shiekh RA, Malik MA, Al-Thabaiti SA, Wani MY, Nabi A
    ScientificWorldJournal, 2014;2014:404617.
    PMID: 24772018 DOI: 10.1155/2014/404617
    2-Phenyl-N,N'-bis(pyridin-4-ylcarbonyl)butanediamide ligand with a series of transition metal complexes has been synthesized via two routes: microwave irradiation and conventional heating method. Microwave irritation method happened to be the efficient and versatile route for the synthesis of these metal complexes. These complexes were found to have the general composition M(L)Cl2/M(L)(CH3COO)2 (where M = Cu(II), Co(II), Ni(II), and L = ligand). Different physical and spectroscopic techniques were used to investigate the structural features of the synthesized compounds, which supported an octahedral geometry for these complexes. In vitro antifungal activity of the ligand and its metal complexes revealed that the metal complexes are highly active compared to the standard drug. Metal complexes showed enhanced activity compared to the ligand, which is an important step towards the designing of antifungal drug candidates.
  4. Khan I, Bilal M, Khaliq W, Khan N, Khahro SH, Memon ZA, et al.
    Sci Rep, 2024 Nov 27;14(1):29480.
    PMID: 39604467 DOI: 10.1038/s41598-024-79869-z
    Bitumen exhibits viscoelastic properties, showcasing both viscous and elastic behaviors, which are characterized by the phase angle and dynamic modulus. Issues like early fatigue fractures, rutting, and permanent deformations in bituminous asphalt pavements arise due to moisture susceptibility, high-temperature deformation, low-temperature cracking, and overloading. These distresses result in potholes, alligator cracks, and specific deformations that lead to early pavement failure, increasing rehabilitation and maintenance costs. To address these issues, this study examines the dynamic modulus and phase angle behavior of Styrene Butadiene Styrene (SBS) modified and unmodified asphalt mixtures. SBS was incorporated in various proportions, ranging from 2 to 7% by the weight of bitumen. The asphalt mixture performance tester (AMPT) was utilized to measure the dynamic modulus at temperatures of 4.4, 21.1, 37.8, and 54.4 °C, and frequencies of 0.1, 0.5, 1, 5, 10, and 25 Hz. The study found significant correlations between dynamic modulus, temperature, loading frequency, and SBS content. Additionally, Multi Expression Programming (MEPX) and regression modeling were employed to estimate the dynamic modulus of SBS-modified HMA. Results indicated that increasing SBS content up to 7% decreased penetration and ductility values by up to 46% and 56%, respectively, while raising the softening point by 63% due to increased stiffness. The blend with 6% SBS by weight of bitumen exhibited superior performance compared to other mixtures. Phase angle initially increased with rising temperature, peaking at 37.8 °C at lower frequencies, and continued to increase at higher frequencies. Isothermal and isochronal plots showed that the 0% SBS mix had a higher phase angle due to increased bitumen content. Overall, the HMA mix with 6% SBS provided the best outcomes.
  5. Haagsma JA, James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, et al.
    Inj Prev, 2020 Oct;26(Supp 1):i12-i26.
    PMID: 31915273 DOI: 10.1136/injuryprev-2019-043296
    BACKGROUND: The epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjusted life years (DALYs) from injury for 195 countries and territories at different levels along the development spectrum between 1990 and 2017 based on the Global Burden of Disease (GBD) 2017 estimates.

    METHODS: Injury mortality was estimated using the GBD mortality database, corrections for garbage coding and CODEm-the cause of death ensemble modelling tool. Morbidity estimation was based on surveys and inpatient and outpatient data sets for 30 cause-of-injury with 47 nature-of-injury categories each. The Socio-demographic Index (SDI) is a composite indicator that includes lagged income per capita, average educational attainment over age 15 years and total fertility rate.

    RESULTS: For many causes of injury, age-standardised DALY rates declined with increasing SDI, although road injury, interpersonal violence and self-harm did not follow this pattern. Particularly for self-harm opposing patterns were observed in regions with similar SDI levels. For road injuries, this effect was less pronounced.

    CONCLUSIONS: The overall global pattern is that of declining injury burden with increasing SDI. However, not all injuries follow this pattern, which suggests multiple underlying mechanisms influencing injury DALYs. There is a need for a detailed understanding of these patterns to help to inform national and global efforts to address injury-related health outcomes across the development spectrum.

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