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  1. Fulltext Microstrain, particle size and lattice constant of CaCO3 ceramic by Rietveld analysis
    Irzaman, Jamal, Z., Idris, M.S., Kurnia, D., Barmawi, M.
    Journal of Nuclear and Related Technologies, 2007;2005(1):43-46.
    MyJurnal
    The specimens used were CaCO3 (Sigma Aldrich, purity 99.9 %). We have 23 parameters and 20 iterations, including two theta zero error, scale factor, thermal effect, coefficients for polynomial describing the background; U, V, W and mixing parameters of the profile peak function, lattice constants, positional parameters and overall isotropic temperature factors. Most the samples show that the crystal structure are rhombohedral with lattice constants a = b = 4.981 Å, c = 17.044 Å and space group is R3C. The microstrain (K) and the particle size (V) of CaCO3 ceramic were calculated using 10 the full width at half maximum (FWHM) of diffraction peaks from (0 1 2), (1 0 4), (0 0 6), (1 1 0), (1 1 3), (2 0 2), (0 1 8), (1 1 6), (2 2 1 ), (1 2 2) crystal planes are 2.1 x 10-2 and
    362 nm, respectively.
  2. Prognostic role of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in critically ill COVID-19 patients: A retrospective study
    Wulandari W, Syahrul MZ, Ermayanti S, Rofinda ZD, Usman E, Kurnia D, et al.
    Med J Malaysia, 2024 Nov;79(6):743-748.
    PMID: 39614793
    INTRODUCTION: Critical coronavirus disease (COVID-19) patients have a high mortality rate. To identify high-risk patients, first-level healthcare facilities can use the neutrophil-lymphocyte ratio (NLR) and the plateletlymphocyte ratio (PLR) as prognostic markers. We aimed to assess the NLR and the PLR profile in critically ill COVID-19 patients to predict disease severity.

    MATERIALS AND METHODS: This descriptive retrospective study featured 221 patients diagnosed with clinically critical COVID-19 from August 2021 to March 2022 in the Intensive Care Unit (ICU) of RSUP Dr. M. Djamil, Padang, Indonesia. The study employed a total sampling technique to collect data from medical records in the hospital. Patients aged 18 years or older who underwent testing for leukocytes, platelets, neutrophils, and lymphocytes were included in the study. We analysed the data using descriptive univariate analysis. Then, the NLR and PLR of the patients were statistically compared based on comorbidities and coincidence.

    RESULTS: According to the study, most patients with critically ill COVID-19 exhibited high levels of NLR (88.2%) and PLR (71.1%). The severe COVID-19 patients with comorbidity of kidney disease had the highest NLR (Mean ± SD) of 31.74 ± 27.95 (p-value <0.001) and the highest mean PLR (Mean ± SD) of 469.33 ± 362.95 (p-value 0.001).

    CONCLUSION: Our findings showed a significantly higher NLR and PLR in patients with critically ill COVID-19, particularly in patients with comorbidity of kidney disease. Thus, elevated levels of NLR and PLR were identified as potential prognostic markers for predicting disease severity in COVID-19 patients, especially those with kidney comorbidity.

  3. A new antiplasmodial sterol from Indonesian marine sponge, Xestospongia sp
    Murtihapsari M, Salam S, Kurnia D, Darwati D, Kadarusman K, Abdullah FF, et al.
    Nat Prod Res, 2021 Mar;35(6):937-944.
    PMID: 31210054 DOI: 10.1080/14786419.2019.1611815
    A new antimalarial sterol, kaimanol (1), along with a known sterol, saringosterol (2) was isolated from the Indonesian Marine sponge, Xestospongia sp. The chemical structure of the new compound was determined on the basis of spectroscopic evidences and by comparison to those related compounds previously reported. Isolated compounds, 1 and 2 were evaluated for their antiplasmodial effect against Plasmodium falciparum 3D7 strains. Compounds 1 and 2 exhibited antiplasmodial activity with IC50 values of 359 and 0.250 nM, respectively.
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