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  1. Kumaresan R, Pendayala S, Srinivasan B, Kondreddy K
    Indian J Dent Res, 2014 Jul-Aug;25(4):541-3.
    PMID: 25307925 DOI: 10.4103/0970-9290.142577
    OBJECTIVES: The purpose of this paper is to develop a simple and cost-effective suturing training model.
    MATERIALS AND METHODS: A simplified suturing model is developed for preclinical training purpose. The training model requires only three easily available materials, which include synthetic foam sponge, elastomeric impression material and putty impression material. Construction of this model requires only 15 min.
    RESULTS: The training model thus developed resembles a realistic human tissue with a skin analog, deeper connective tissues and a bony base. This enables the students to practice various suturing technique at different tissue planes. Such practice helps the students to perform a live procedure in a more skilled and less traumatic way.
    CONCLUSION: The easy availability and cost-effective nature of the materials, in concert with fast construction time, makes this suturing model appropriate when an affordable alternative is desired.
  2. Perti S, Mansuri S, Pilli J, Kaur A, Alwithanani N, Kondreddy K
    J Pharm Bioallied Sci, 2023 Jul;15(Suppl 1):S187-S191.
    PMID: 37654361 DOI: 10.4103/jpbs.jpbs_450_22
    INTRODUCTION: Recurrent abutment substitutions may physically irritate the mucosal (soft tissue) barrier, which may cause additional toxic irritants and germs to enter the mucosal implant barrier and weaken the tissues surrounding implant. The creation of a "definitive abutment" may lessen the likelihood of tissue losses around the implant. Determining the characters of the peri-implant tissue after the placement of the definitive abutments and multiple abutment replacement was the goal of this study.

    MATERIALS AND PROCEDURES: Forty missing teeth were replaced with implants in matched subjects. Parameters assessed were "distance of cement enamel junction to alveolar crest and distance of CEJ to gingival margin; bleeding on probing, Sulcus probing depth, and peri-implant marginal bone loss." Subjects were randomly assigned for the two groups of intervention. All the measurements were documented at designated timelines and compared for the statistical variance where P < 0.05 was considered as significant.

    RESULTS: In the control and test groups, the peri-implant marginal bone level rose from baseline to 3 months. There were no appreciable differences between the CEJ-AC and CEJ-GM groups when the clinical and radiographic parameters of each group were evaluated. Throughout all of the time points, the soft tissue borders in both groups remained comparably steady.

    CONCLUSION: The study's findings suggest that using implants with definite abutments is more advantageous for obtaining better maintenance in terms of the health of the tissues that surround the implants.

  3. Karpathak S, Mansuri S, Dev SV, Pilli J, Alwithanani N, Kondreddy K
    J Pharm Bioallied Sci, 2023 Jul;15(Suppl 1):S183-S186.
    PMID: 37654403 DOI: 10.4103/jpbs.jpbs_449_22
    INTRODUCTION: In many oral procedures that involve the implants, hair implantations, "Platelet-Rich Fibrin Membrane (PRF)" is commonly applied. The advantages are many. In this study, the mechanical resistance of PRF under resistance pull on a longitudinal axis was assessed and compared.

    MATERIAL AND METHODS: For the current in vitro study, 60 volunteers donated each 10 ml of their blood and hence a total volume of 600 ml of blood was procured that was analyzed for the current study. The total volume was grouped to three groups where they receive three resistance centrifugation forces of "F-200,600,800 m/s²." In each group, 20 samples were tested for each level of the G-resistance. Each group was further divided as two subgroups of different times of wait, where they were centrifuged at baseline time and after a stand of 30 minutes. On universal testing equipment, the PRF membranes were mechanically tensioned in order to determine each membrane's resistance force. These values were compared for any statistical variance using appropriate statistical tools keeping P < 0.05.

    RESULTS: Any applied force had no statistically significant effect on the centrifugation duration for membrane resistance. When the resistance was applied for the PRP samples immediately after they were procured, no significant variation was seen at all the grades of the centrifugation forces; consequently, the T30 group showed a statistically significant variance for the centrifugation forces applied (P = 0.04), with the highest value when the greatest force was applied. According to the results, the centrifugation waiting period could be determined based on the application requirement.

    CONCLUSION: For immediate membrane usage, the centrifugation had no effect on resistance; however, after 30 minutes, a membrane with greater resistance was produced by applying more force.

  4. Thakur S, Kadam H, Jha S, Lall A, Kondreddy K, Singh A
    J Pharm Bioallied Sci, 2021 Nov;13(Suppl 2):S1713-S1716.
    PMID: 35018061 DOI: 10.4103/jpbs.jpbs_108_21
    BACKGROUND: Patients around the world when attending the dental clinic are prone to undergo the feelings of fear and anxiety. This may impact the dental follow-up and prognosis.

    AIM: The aim of the study is to evaluate the dental anxiety in the patients attending for the dental treatment in a college, in India.

    MATERIALS AND METHODS: A sample of 500 adults with ages 15-60 years was considered for the study. Modified dental anxiety questionnaire was used in the present study to assess the anxiety faced by the patients attending for the dental treatment. ANOVA and Chi-square test were used to test for the significance between the variables, and the correlation between these variables was assessed using the Spearman's correlation. Likert scale was used to know the cutoff for the severity of the dental anxiety.

    RESULTS: Only in the 4% of the participants in the present study had dental anxiety. Gender, age, financial status, education impacted the dental anxiety and the regularity toward the appointments.

    CONCLUSION: It can be concluded from our study that there was a low anxiety in the dental patients toward the dental treatment and also anxiety decreased with the age. However, regular dental visits are advised to prevent the overall impact of the oral health on the general health.

  5. Ramya K, Deshpande A, Deepika ADN, Rayudu GS, Pendyala SK, Kondreddy K
    J Oral Maxillofac Pathol, 2021 05 14;25(1):189-192.
    PMID: 34349434 DOI: 10.4103/jomfp.jomfp_17_21
    Background: To emphasize the role of odontometric parameters which may be used as a reliable forensic tool especially in cases with partial remains of the individual.

    Aim: To assess the reliability of odontometric parameters in stature analysis.

    Materials and Methods: The study was conducted on 100 patients (50 male and 50 Female). Mesiodistal width of anterior teeth, inter-canine width, Inter-premolar width and maxillary arch length were the parameters included. The results were tabulated with a linear regression formula obtained for each parameter.

    Statistical Analysis: The data collected was statistically analysed using SPSS version 20 and a linear regression formula was obtained thereafter.

    Results: Mesio-distal widths of individual maxillary canines, total mesiodistal width of maxillary anteriors and arch length showed a significant co-relation with stature. The combined linear regression formula was obtained for all parameters.

    Conclusion: Odontometric parameters of mesio - distal widths of individual maxillary canines, total mesiodistal width of maxillary anteriors and arch length can be used as reliable parameters for stature analysis.

  6. Majeed R, Sathi KV, Patil RS, Singh N, Duseja S, Kondreddy K
    J Pharm Bioallied Sci, 2024 Feb;16(Suppl 1):S215-S218.
    PMID: 38595612 DOI: 10.4103/jpbs.jpbs_464_23
    Antidepressants have anti-inflammatory effects and boost immunity, and dentists should be aware. This case-control study included only those patients who consented to take part and had a ham-d score of at least 16 and a diagnosis of moderate-to-severe depression. Inclusion criteria included adults, those experiencing moderate to severe depression, taking fluoxetine or venlafaxine, and those with twenty or more teeth. Exclusion criteria included tobacco chewers, smokers, women expecting or nursing, periodontal treatment, antibiotics, anti-inflammatory medication, or vitamin/nutritional supplements. Patients who had had surgery or other therapy were excluded from the study. Three groups of patients were created: Control, venlafaxine, and fluoxetine. A periodontist assisted in the dental examination, and indices were observed. The analysis was done using Statistical Package for the Social Sciences (SPSS) version 24.0. Number, percentage, mean, and standard deviation were used to present the values. Results showed that antidepressants may be a risk factor for periodontal health, with increased periodontal parameters, and concluded that It is crucial to frequently check the periodontal health of depressed people using fluoxetine or venlafaxine since these drugs put good periodontal tissues at risk.
  7. Baddam H, Vivekanandan G, Kondreddy K, Peddi S, Chitnis PP, Singh YP, et al.
    J Pharm Bioallied Sci, 2021 Nov;13(Suppl 2):S1275-S1279.
    PMID: 35017970 DOI: 10.4103/jpbs.jpbs_90_21
    BACKGROUND: Periodontitis is a chronic inflammatory disease with conglomerate etiology making it difficult to diagnose at the early stages. Potential biomarkers in gingival crevicular fluid (GCF) would determine the presence of the current disease activity, predict sites vulnerable for future breakdown, and assess the response to periodontal interventions. Merely elevated levels of inflammatory soft-tissue markers do not indicate bone destruction. Since there is no single ideal biomarker established, bone-related biomarkers such as telopeptide of type I collagen, osteocalcin, calprotectin, osteopontin, and tartrate-resistant acid phosphatase (TRAP) seem to hold great promise as predictive markers to determine bone destruction and active phases in the disease progression. The present study is intended to explore the biologic plausibility of the levels of TRAP in health and chronic periodontitis.

    MATERIALS AND METHODS: The present cross-sectional clinico-biochemical study comprised 30 systemically healthy subjects with 15 periodontally healthy and 15 chronic periodontitis subjects who were age and gender matched. GCF and blood samples were collected from all the patients. TRAP estimation was done in both the samples using an enzyme-linked immunosorbent assay kit. The data were analyzed using independent t-test and Pearson correlation test.

    RESULTS: Serum and GCF TRAP levels in chronic periodontitis subjects were significantly higher when compared to the periodontally healthy group. There were no significant correlations found among serum and GCF TRAP levels with increasing age and gender in both the groups. An increase in disease severity, i.e., increase in probing pocket depth and clinical attachment level, did not show correlation with the GCF and serum TRAP levels in the chronic periodontitis group.

    CONCLUSION: Based on the findings of the present study, increased GCF TRAP levels in chronic periodontitis seem to be a potential marker for identifying ongoing periodontal destruction.

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