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  1. Fulltext Total Phenolic Content and Antioxidant and Antibacterial Activities of Pereskia bleo
    Johari MA, Khong HY
    Adv Pharmacol Sci, 2019;2019:7428593.
    PMID: 30719037 DOI: 10.1155/2019/7428593
    Different solvent extracts of Pereskia bleo leaves were evaluated for total phenolic content (TPC) and antioxidant activities based on the Folin-Ciocalteu test and DPPH scavenging activities. The antibacterial activities against four bacteria, namely, Gram-positive bacteria: Streptococcus pyogenes ATCC 19615 (SP) and Staphylococcus aureus ATCC 29737 (SA) and Gram-negative bacteria: Escherichia coli ATCC 10536 (EC) and Pseudomonas aeruginosa ATCC 9027 (PA), were also performed based on the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays. The findings demonstrated that both the methanolic and chloroform extracts displayed strong activities against SA, SP, EC, and PA while the hexane extract demonstrated the weakest activities towards all the four bacteria. The methanolic extract also exhibited higher TPC and possessed higher antioxidant activity with the IC50 value 33.83 µg/mL compared to the chloroform and hexane extracts. As such, the methanolic extract has a higher ability to scavenge free radical compared to other extracts. Due to the interesting result, activities are shown by the methanolic and chloroform crude extracts of P. bleo; hence, the study has been extended to the isolation of bioactive compounds to uncover its great potential as a natural source for antibacterial and antioxidant agents.
  2. Ammoniacal nitrogen and COD removal from semi-aerobic landfill leachate using a composite adsorbent: fixed bed column adsorption performance
    Halim AA, Aziz HA, Johari MA, Ariffin KS, Adlan MN
    J Hazard Mater, 2010 Mar 15;175(1-3):960-4.
    PMID: 19945216 DOI: 10.1016/j.jhazmat.2009.10.103
    The performance of a carbon-mineral composite adsorbent used in a fixed bed column for the removal of ammoniacal nitrogen and aggregate organic pollutant (COD), which are commonly found in landfill leachate, was evaluated. The breakthrough capacities for ammoniacal nitrogen and COD adsorption were 4.46 and 3.23 mg/g, respectively. Additionally, the optimum empty bed contact time (EBCT) was 75 min. The column efficiency for ammoniacal nitrogen and COD adsorption using fresh adsorbent was 86.4% and 92.6%, respectively, and these values increased to 90.0% and 93.7%, respectively, after the regeneration process.
  3. Fulltext Osteoporosis Knowledge among Future Healthcare Practitioners: Findings from a Malaysian Public University
    Elnaem MH, Jamshed SQ, Elkalmi RM, Baharuddin MF, Johari MA, Aziz NABA, et al.
    J Pharm Bioallied Sci, 2017;9(2):115-120.
    PMID: 28717334 DOI: 10.4103/jpbs.JPBS_336_16
    BACKGROUND AND OBJECTIVES: Students in relevant health-care academic programs are the future professionals who should play an active role in increasing community awareness regarding chronic diseases such as osteoporosis. This research aimed to evaluate the knowledge of osteoporosis, one of the growing health-care burdens in Malaysia, among students belong to three different health occupations programs in a Malaysian University.

    METHODS: A cross-sectional study design was conducted to assess the level of knowledge on osteoporosis and to explore the potential association between the study program and osteoporosis-related knowledge among medicine, pharmacy, and allied health sciences students in a Malaysian University. A total of 348 students were approached. The data were collected using validated revised Osteoporosis Knowledge Test questionnaire.

    RESULTS: The results showed variability in knowledge score between students belonging to different study programs. allied health sciences students have the highest overall total score (median = 20) and nutrition score (median = 16), but for exercise score, both students in allied health sciences and medicine programs shared a similar median score (median = 11.5). More than half of the respondents showed adequate knowledge on osteoporosis. The students from allied health sciences exhibited more knowledge on osteoporosis compared to students in other study programs. Among the Kulliyyah of Pharmacy respondents, the majority did not manage to answer correctly on the whole scale. This was evident by total percentage of 69.91% of the respondents scored below than median score.

    CONCLUSION: There is a considerable gap of knowledge regarding osteoporosis among students in various health occupations academic programs. Pharmacy students particularly need focused learning related to exercise and nutrition in preventing osteoporosis during their academic program.

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