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Fulltext Aesthetic Management of Fluoresced Teeth with Ceramic Veneers and Direct Composite Bonding - An Overview and A Case Presentation

Jhajharia K, Shah HH, Paliwal A, Parikh V, Patel S

J Clin Diagn Res, 2015 Jun;9(6):ZD28-30.
PMID: 26266231 DOI: 10.7860/JCDR/2015/12542.6108

Tooth discolouration is a common problem and affects people of all ages. Apart from the conventional treatment modalities for the same, newer options are available today with better techniques and materials. The present case report describes a 17-year-old girl who had stained and pitted teeth, attributable to dental fluorosis and she desired aesthetic treatment for the same. The pros and cons of all treatment options were carefully weighed and a multistep treatment process involving ceramic veneers and direct bonding were planned. The execution of the planned treatment yielded a good aesthetic and functional outcome.
Fulltext Biofilm in endodontics: A review

Jhajharia K, Parolia A, Shetty KV, Mehta LK

J Int Soc Prev Community Dent, 2015 Jan-Feb;5(1):1-12.
PMID: 25767760 DOI: 10.4103/2231-0762.151956

Endodontic disease is a biofilm-mediated infection, and primary aim in the management of endodontic disease is the elimination of bacterial biofilm from the root canal system. The most common endodontic infection is caused by the surface-associated growth of microorganisms. It is important to apply the biofilm concept to endodontic microbiology to understand the pathogenic potential of the root canal microbiota as well as to form the basis for new approaches for disinfection. It is foremost to understand how the biofilm formed by root canal bacteria resists endodontic treatment measures. Bacterial etiology has been confirmed for common oral diseases such as caries and periodontal and endodontic infections. Bacteria causing these diseases are organized in biofilm structures, which are complex microbial communities composed of a great variety of bacteria with different ecological requirements and pathogenic potential. The biofilm community not only gives bacteria effective protection against the host's defense system but also makes them more resistant to a variety of disinfecting agents used as oral hygiene products or in the treatment of infections. Successful treatment of these diseases depends on biofilm removal as well as effective killing of biofilm bacteria. So, the fundamental to maintain oral health and prevent dental caries, gingivitis, and periodontitis is to control the oral biofilms. From these aspects, the formation of biofilms carries particular clinical significance because not only host defense mechanisms but also therapeutic efforts including chemical and mechanical antimicrobial treatment measures have the most difficult task of dealing with organisms that are gathered in a biofilm. The aim of this article was to review the mechanisms of biofilms' formation, their roles in pulpal and periapical pathosis, the different types of biofilms, the factors influencing biofilm formation, the mechanisms of their antimicrobial resistance, techniques to identify biofilms.
Fulltext An ex-vivo comparative study of root-end marginal adaptation using grey mineral trioxide aggregate, white mineral trioxide aggregate, and Portland cement under scanning electron microscopy

Baranwal AK, Paul ML, Mazumdar D, Adhikari HD, Vyavahare NK, Jhajharia K

J Conserv Dent, 2015 Sep-Oct;18(5):399-404.
PMID: 26430305 DOI: 10.4103/0972-0707.164054

Where nonsurgical endodontic intervention is not possible, or it will not solve the problem, surgical endodontic treatment must be considered. A major cause of surgical endodontic failures is an inadequate apical seal, so the use of the suitable substance as root-end filling material that prevents egress of potential contaminants into periapical tissue is very critical.
Fulltext Multidrug resistance 1 gene polymorphism in amlodipine-induced gingival enlargement

Naik KN, Jhajharia K, Chaudhary R, Tatikonda A, Dhaliwal AS, Kaur RK

J Indian Soc Periodontol, 2015 5 28;19(2):239-41.
PMID: 26015682 DOI: 10.4103/0972-124X.145837

Gingival enlargement comprises any clinical condition in which an increase in the size of the gingiva is observed. It is a side effect associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressant, and calcium channel blockers. Among calcium channel blockers, nifedipine causes gingival enlargement in about 10% of patients, whereas the incidence of amlodipine, a third-generation calcium channel blocker, induced gingival enlargement is very limited. Because the calcium antagonists, albeit to a variable degree, act as inhibitors of P-glycoprotein (P-gp), the gene product of multidrug resistance 1 (MDR1), and inflammation may modify P-gp expression. We hereby, report a case of amlodipine-induced gingival enlargement with MDR1 3435C/T polymorphism, associated with inflammatory changes due to plaque accumulation, in a 50-year-old hypertensive male patient. The genotype obtained for the polymorphism was a heteromutant genotype, thus supporting the contention that the MDR1 polymorphism may alter the inflammatory response to the drug.
Fulltext Comparison of the Effect for Fracture Resistance of Different Coronally Extended Post Length with Two Different Post Materials

Chauhan NS, Saraswat N, Parashar A, Sandu KS, Jhajharia K, Rabadiya N

J Int Soc Prev Community Dent, 2019 04 12;9(2):144-151.
PMID: 31058064 DOI: 10.4103/jispcd.JISPCD_334_18

Aims and Objectives: To compare the effect for fracture resistance of different coronally extended post length with two different post materials.
Materials and Methods: One hundred and sixty endodontically treated maxillary central incisors embedded in acrylic resin with decoronated root portion were taken for the study. The postspaces were prepared according to standard protocol. The samples were divided into two groups according to the post material: glass-fiber post and Quartz fiber post. These groups were further subdivided on the basis of coronal extension of 4 and 6 mm for glass fiber and Quartz fiber posts, respectively. The posts were then luted with dual-polymerizing resin cement followed by core buildup. Samples were subjected to increasing compressive oblique load until fracture occurred in a universal testing machine. Data were analyzed with one-way ANOVA and independent Student's t-test. Analysis was done using SPSS version 15 (SPSS Inc., Chicago, IL, USA) Windows software program.
Results: Glass fiber post with coronal extension of 4 mm (182.8 N) showed better results than with 6-mm length (124.1 N). Similarly, in quartz fiber posts group, 4-mm postlength (314 N) was better when compared with 6 mm (160 N). The 4-mm coronal extension of quartz fiber post displayed superior fracture resistance.
Conclusions: Glass fiber posts showed better fracture resistance than Quartz fiber posts. 4-mm coronal length showed more fracture resistance than 6 mm.
Fulltext An in vitro evaluation of the effect of dentin deproteinization on coronal microleakage in endodontically treated teeth

Shetty KV, Jhajharia K, Chaurasia VR, Jhamb A, Rohra V, Sharma AM

J Int Soc Prev Community Dent, 2014 Dec;4(Suppl 3):S187-92.
PMID: 25625077 DOI: 10.4103/2231-0762.149036

The most common cause of failure of endodontic therapy is inadequate apical and coronal seal. Proper coronal seal reduces the risk of endodontic failure. Hence, the present study was done to test the role of self-etching primers in reducing microleakage through coronal seal.