To investigate the depression, anxiety and stress, stressors and relieving factors among dental students at Kulliyyah of Dentistry (KOD). Materials and methods:A cross-sectional study was conducted among 222 dental students. Their socio-demographic data, self-reported depression, anxiety and stress (DASS-21) scores, causes and relieving factors were collected using validated semi-structured pre-tested questionnaires. The data was analysed using percentages, chi-square test and Binary logistic regression tests with SPSS version 24. Results:The prevalence of depression, anxiety and stress was 41%, 68.9% and 34.2% respectively.Cross analysis showed that academic-related and laboratory or clinical related reasons were significantly associated with the depressive symptoms [(X2= 15.86, p