Gas turbine cooling can be classified into two different schemes; internal and external
cooling. In the internal cooling method, the coolant provided by compressor is forced into the cooling
flow circuits inside turbine components. Meanwhile, for the external cooling method, the injected
coolant is directly perfused from coolant manifold to save downstream components from hot gases.
Furthermore, in the latter coolant scheme, coolant is used to quell the heat transfer from hot gas stream
to a component. There are several ways in external cooling. Film cooling is one of the best cooling
systems for the application on gas turbine blades. This study concentrates on the comparison of
experimental, computational and numerical investigations of advanced film cooling performance for
cylindrical holes at different angles and different blowing ratios in modern gas turbines.
Evidence on rising global temperature, melting of ice caps, and withdrawal of glaciers
brings attentions to the enhancement of energy efficiency in energy intensive industries. Having a
realistic comparison between one plant and the best practice technology (BPT) in operation in the field
helps significantly to distinguish and diagnose the potentials where measures towards energy efficiency
improvement would be applicable. In this regard, for manufacturing industries, one of the most widely
used energy benchmarking tools is the Energy Benchmark Curve. An energy benchmark curve plots the
efficiency of plants as a function of the total production volume from all similar plants or as a function
of the total number of plants that operate at that level of efficiency or worse. This paper reviews the
methodology through which the benchmark curve is obtained for a specific industry followed by a
comparison of energy intensity for the iron and steel industry among China and the US. According to
the international energy benchmark curve for the iron and steel industry, the savings potentials per ton
of crude steel for the US. and China have been respectively 4.1 and 7.1 gigajoule comparing with the
BPT in the field. Finally, an overview over certain measures to enhance efficiency of such plants is
presented.
Background: Several studies indicate a high prevalence of depression around the world during the period of the COVID-19 pandemic. Using a valid instrument to capture the depression of an individual in this situation is both important and timely. The present study aims to evaluate the psychometric properties of the Persian version of the Center for Epidemiological Studies Depression Scale (CES-D) among the public during the COVID-19 pandemic in Iran. Method: This is a cross-sectional study that was conducted in the Iranian population (n = 600) from April to July 2020. A two-part online form was used: sociodemographic characteristics and depression items (CES-D). The construct validity and internal consistency reliability of the scale were evaluated. Result: The results of the exploratory factor analysis illustrated two factors with 43.35% of the total variance of the depression were explained. Confirmatory factor analysis indicated that this model fits well. Internal consistency reliability was evaluated, and it was acceptable. Conclusion: The findings demonstrated that, in the Iranian sample, this depression scale yielded two factors (somatic and positive affects) solutions with suitable psychometric properties.
Overlapping disease aetiologies associated with multiple altered biological processes have been identified that change the endometrial function leading to recurrent implantation failure (RIF) and recurrent early pregnancy loss (REPL). We aimed to provide a detailed insight into the nature of the biological malfunction and related pathways of differentially expressed genes in RIF and REPL. Endometrial biopsies were obtained from 9 women experiencing RIF, REPL and control groups. Affymetrix microarray analysis was performed to measure the gene expression level of the endometrial biopsies. Unsupervised clustering of endometrial samples shows scattered distribution of gene expression between the RIF, REPL and control groups. 2556 and 1174 genes (p value < 0.05, Fold change > 1.2) were significantly altered in the endometria of RIF and REPL patients’ group, respectively compared to the control group. Downregulation in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of the differentially expressed genes (DEGs) in RIF and REPL including ribosome and oxidative phosphorylation pathways. Gene Ontology (GO) analysis revealed ribosomes and mitochondria inner membrane as the most significantly downregulated cellular component (CC) affected in RIF and REPL. Determination of the dysregulated genes and related biological pathways in RIF and REPL will be key in understanding their molecular pathology and of major importance in addressing diagnosis, prognosis, and treatment issues