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  1. Mohamed NA, Alanzi ARA, Azizan AN, Azizan SA, Samsudin N, Salarzadeh Jenatabadi H
    PLoS One, 2024;19(1):e0290376.
    PMID: 38261595 DOI: 10.1371/journal.pone.0290376
    Sustainable construction and demolition waste management relies heavily on the attitudes and actions of its constituents; nevertheless, deep analysis for introducing the best estimator is rarely attained. The main objective of this study is to perform a comparison analysis among different approaches of Structural Equation Modeling (SEM) in Construction and Demolition Waste Management (C&DWM) modeling based on an Extended Theory of Planned Behaviour (Extended TPB). The introduced research model includes twelve latent variables, six independent variables, one mediator, three control variables, and one dependent variable. Maximum likelihood (ML), partial least square (PLS), and Bayesian estimators were considered in this study. The output of SEM with the Bayesian estimator was 85.8%, and among effectiveness of six main variables on C&DWM Behavioral (Depenmalaydent variables), five of them have significant relations. Meanwhile, the variation based on SEM with ML estimator was equal to 78.2%, and four correlations with dependent variable have significant relationship. At the conclusion, the R-square of SEM with the PLS estimator was equivalent to 73.4% and three correlations with the dependent variable had significant relationships. At the same time, the values of the three statistical indices include root mean square error (RMSE), mean absolute percentage error (MPE), and mean absolute error (MSE) with involving Bayesian estimator are lower than both ML and PLS estimators. Therefore, compared to both PLS and ML, the predicted values of the Bayesian estimator are closer to the observed values. The lower values of MPE, RMSE, and MSE and the higher values of R-square will generate better goodness of fit for SEM with a Bayesian estimator. Moreover, the SEM with a Bayesian estimator revealed better data fit than both the PLS and ML estimators. The pattern shows that the relationship between research variables can change with different estimators. Hence, researchers using the SEM technique must carefully consider the primary estimator for their data analysis. The precaution is necessary because higher error means different regression coefficients in the research model.
  2. Kiew LV, Munavvar AS, Law CH, Azizan AN, Nazarina AR, Sidik K, et al.
    J Physiol, 2004 Jun 15;557(Pt 3):981-9.
    PMID: 15047774
    An antisense oligodeoxynucleotide (As-ODN) to the 3' untranslated region of the mRNA sequence expressing the intracellular adhesion molecule-1 (ICAM-1) was employed to determine ICAM-1's role in renal ischaemia-reperfusion injury in the rat. Wistar-Kyoto rats receiving i.v. either lipofectin-As-ODN (As-ODN group), lipofectin-reverse ODN (Rv-ODN group) or lipofectin (ischaemia control group) 8 h prior to study were anaesthetized and subjected to 30 min of renal artery occlusion. Renal haemodynamic and excretory parameters were monitored before and after renal ischaemia. On termination of the study renal tissue was subjected to histological and Western blot analysis. Renal blood flow decreased in the 3 h post-ischaemia period in the ischaemia control and Rv-ODN groups, but was maintained in the As-ODN group. Glomerular filtration rate was depressed initially but gradually increased to 10% above basal levels in the ischaemia control and Rv-ODN groups, but was below basal levels (20%) in the As-ODN group. There was a three- to fourfold increase in sodium and water excretion following ischaemia in the ischaemia control and reverse-ODN groups but not in the As-ODN treated group. The As-ODN ameliorated the histological evidence of ischaemic damage and reduced ICAM-1 protein levels to a greater extent in the medulla than cortex. These observations suggested that in the post-ischaemic period afferent and efferent arteriolar tone was increased with a loss of reabsorptive capacity which was in part due to ICAM-1. The possibility arises that the action of ICAM-1 at vascular and tubular sites in the deeper regions of the kidney contributes to the ischaemia-reperfusion injury.
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