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Diffuse scattering from hemispherical nanoparticles at the air-silicon interface

Centeno A, Ahmed B, Reehal H, Xie F

Nanotechnology, 2013 Oct 18;24(41):415402.
PMID: 24045859 DOI: 10.1088/0957-4484/24/41/415402

There has been much recent interest in the application of plasmonics to improve the efficiency of silicon solar cells. In this paper we use finite difference time domain calculations to investigate the placement of hemispherical gold nanoparticles on the rear surface of a silicon solar cell. The results indicate that nanoparticles protruding into the silicon, rather than into air, have a larger scattering efficiency and diffuse scattering into the semiconductor. This finding could lead to improved light trapping within a thin silicon solar cell device.
Gramine inhibits angiogenesis and induces apoptosis via modulation of TGF-β signalling in 7,12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma

Ramu A, Kathiresan S, Ali Ahmed B

Phytomedicine, 2017 Sep 15;33:69-76.
PMID: 28887922 DOI: 10.1016/j.phymed.2017.05.008

BACKGROUND: Transforming growth factor-β (TGF-β) and its receptors are considered as a novel target in cancer chemotherapy. Gramine, an indole alkaloid, possesses various pharmacological properties including antiproliferative and anticancer. However, the anti-angiogenic property remains unexplored.
PURPOSE: The present study was designed to evaluate the anti-angiogenic and apoptosis induction properties of gramine through inhibiting TGF-β on DMBA induced oral squamous cell carcinoma (OSCC) in the hamster buccal pouch (HBP).
METHODS: The effects of gramine on TGF-β signalling in DMBA induced carcinogenic events such as angiogenesis and apoptosis were analysed by studying the mRNA expression using RT-PCR, protein expression by western blot and histopathological analysis using haematoxylin and eosin (H & E) staining.
RESULTS: Gramine significantly inhibited phosphorylation and nuclear translocation of Smad2 and Smad4 by blocking activity of the TGFβ-RII, RI and activation of inhibitory Smad7. Gramine inhibited angiogenic markers such as MMP-2, MMP-9, HIF-1α, VEGF, and VEGF-R2 as well as increased TIMP-2 expression. Furthermore, gramine induced apoptosis in DMBA induced tumour bearing animals by up regulating the pro apoptotic proteins Bax, cytochrome C, apaf-1, caspase-9 caspase-3 and PARP.
CONCLUSION: In this study, we clearly demonstrated that gramine treatment diminishes angiogenesis and induces apoptosis in hamster buccal pouch (HBP) carcinogenesis by modulating TGF-β signals.
Fulltext Why does maxillary skeletal expansion work with some adults and fail with Others?: A narrative review

Allam A, Ahmed B, Ab Rahman N

Saudi Dent J, 2024 Jul;36(7):984-989.
PMID: 39035558 DOI: 10.1016/j.sdentj.2024.04.008

Maxillary skeletal expansion is considered a challenging treatment modality in adult ages. Mini-screw-assisted rapid palatal expansion (MARPE) is considered a pioneer in providing a solution for maxillary deficiency in adults away from any surgical interventions. If we consider patient cooperation and motivation, together with operator skills, as constant factors during MARPE, and exclude all hygiene and soft tissue complications that jeopardise the appliance's stability, there is a percentage of expansion failure recorded in different studies with no emphasis on what makes mid-facial diastema appear in some, rather than others. Electronic databases including PubMed, Scopus, Google Scholar, and Web of Science, were searched for literature published in English till 2023. Failure was related in some literature to different criteria, as of yet, no verifiable indicators would allow us to determine success or failure in advance. This review highlighted the most common reasons for failure discussed in different literature: Chronological Age, Mid-palatal suture maturation, Bone density, Sex, Race, Appliance design, and Expansion technique used. This study could be considered an attempt to make candidate selection for non-surgical maxillary skeletal expansion at this old age easier, time-saving, and cost less.
Fulltext Karman Vortex Creation Using Cylinder for Flutter Energy Harvester Device

Atrah AB, Ab-Rahman MS, Salleh H, Nuawi MZ, Mohd Nor MJ, Jamaludin NB

Micromachines (Basel), 2017 Jul 21;8(7).
PMID: 30400418 DOI: 10.3390/mi8070227

This study presents the creation of a Karman vortex for a fluttering electromagnetic energy harvester device using a cylinder. The effects of two parameters, which are the diameter and the position of the cylinder, were investigated on the Karman vortex profile and the amplitude of the fluttering belt, respectively. A simulation was conducted to determine the effect of the creation of the Karman vortex, and an experiment was performed to identify influence of the position of the cylinder on the fluttering belt amplitude. The results demonstrated that vortex-induced vibration occurred at the frequency of the first natural mode for the belt at 3 cm and 10 cm for the diameter and position of the cylinder, respectively. Under such configuration, an electromagnetic energy harvester was attached and vibrated via the fluttering belt inside the turbulent boundary layers. This vibration provides a measured output voltage and can be used in wireless sensors.
Fulltext A Comparative Evaluation of Five Obturation Techniques in the Management of Simulated Internal Resorptive Cavities: An Ex Vivo Study

Elenjikal MJ, Latheef AA, Kader MAM, Ganapathy S, Mohamed AB, Sainudeen SS, et al.

J Pharm Bioallied Sci, 2019 May;11(Suppl 2):S450-S456.
PMID: 31198386 DOI: 10.4103/JPBS.JPBS_75_19

Background: Root resorption is the loss of dental hard tissues as a result of clastic activities. It might be broadly classified into external or internal resorption by the location of the resorption in relation to the root surface. the various techniques used these days for filling internal resorption include warm condensation, vertical condensation, core techniques, thermoplasticized gutta-percha, warm vertical compaction, and cold lateral condensation.
Objectives: The aims and objectives of this study were to compare the quality of root fillings in artificially created internal resorption cavities filled with warm vertical compaction, lateral condensation, Obtura II along with System B, E and Q plus along with System B, and Thermafil, and to calculate the percentage of gutta-percha, sealer, and voids using an ImageJ software.
Results: Results between the warm vertical compaction (group I), lateral condensation (group II), Obtura II with System B (group III), E and Q plus with System B (group IV), and Thermafil (group V), group III showed the highest percentage of gutta-percha plus sealer and gutta-percha, and least number of voids, which was statistically significant (P < 0.000).
Conclusion: It can be concluded that Obtura II along with System B was found to be the most suitable obturation technique for the management of teeth exhibiting internal resorption. Thermafil was found to give the poorest obturation quality when used to fill the teeth with internal resorption. Similarly, lateral condensation technique was observed to show maximum sealer and hence was not ideal for the management of internal resorptive cavities.
Traumatic retinal detachment: A contemporary update

Chauhan K, Dave VP, de Ribot FM, Agrawal R, Sallam AB, Andayani G, et al.

Surv Ophthalmol, 2024 Aug 31.
PMID: 39222801 DOI: 10.1016/j.survophthal.2024.08.008

Retinal detachment following ocular trauma (TrRD) is one of the leading causes of blindness and visual impairment worldwide. In the absence of a standardized definition, the diagnosis of traumatic retinal detachment relies on identifying a history of trauma that precedes the detachment. There is an increasing pool of data regarding the etiology and epidemiology of TrRD.Various causes of TrRD mentioned in the literature include work-related eye trauma in construction and manufacturing industries, sports injuries, explosive eye injuries, road traffic accidents, and intraocular foreign bodies. Although there is extensive literature on post-trauma retinal detachments, a comprehensive discussion of its pathogenesis, management, outcomes, and complications is lacking. This article offers an in-depth review of the epidemiology, risk factors, pathogenesis, diagnosis, management, and outcomes of TrRD based on the current literature. A literature review was conducted in PubMed and Google Scholar using the keywords 'ocular trauma,' 'traumatic retinal detachments,' 'open globe injury,' 'closed globe injury,' and 'post-traumatic retinal detachment.'
Fulltext Preliminary Screening of Antioxidant and Antibacterial Activities and Establishment of an Efficient Callus Induction in Curculigo latifolia Dryand (Lemba)

Farzinebrahimi R, Mat Taha R, Rashid KA, Ali Ahmed B, Danaee M, Rozali SE

Evid Based Complement Alternat Med, 2016;2016:6429652.
PMID: 27298625 DOI: 10.1155/2016/6429652

Leaf, seed, and tuber explants of C. latifolia were inoculated on MS medium supplemented with various concentrations of BAP and IBA, alone or in combinations, to achieve in vitro plant regeneration. Subsequently, antioxidant and antibacterial activities were determined from in vitro and in vivo plant developed. No response was observed from seed culture on MS media with various concentrations of PGRs. The highest percentage of callus was observed on tuber explants (94%) and leaf explants (89%) when cultured on MS media supplemented with IBA in combination with BAP. A maximum of 88% shoots per tuber explant, with a mean number of shoots (8.8 ± 1.0), were obtained on MS medium supplemented with combinations of BAP and IBA (2.5 mg L(-1)). The best root induction (92%) and mean number (7.6 ± 0.5) from tuber explants were recorded on 2.5 mg L(-1) IBA alone supplemented to MS medium. The higher antioxidant content (80%) was observed from in vivo tuber. However, tuber part from the intact plant showed higher inhibition zone in antibacterial activity compared to other in vitro and in vivo tested parts.
Fulltext Prevalence of Pediatric Cataract in Asia: A Systematic Review and Meta-Analysis

Tariq MA, Uddin QS, Ahmed B, Sheikh S, Ali U, Mohiuddin A

J Curr Ophthalmol, 2022;34(2):148-159.
PMID: 36147271 DOI: 10.4103/joco.joco_339_21

PURPOSE: To conduct a systematic review and meta-analysis for estimating the prevalence of pediatric cataracts across Asia.
METHODS: A detailed literature search of PubMed, Embase, Web of Science, Cochrane Library, and Google Scholar databases, from 1990 to July 2021, was performed to include all studies reporting the prevalence of cataracts among children. Two researchers performed the literature search and screening of articles independently, and a third researcher critically reviewed the overall search and screening process to ensure the consistency. The JBI Critical Appraisal Checklist for studies reporting prevalence data was used to assess the methodological quality of the included studies.
RESULTS: Of the 496 identified articles, 35 studies with a sample size of 1,168,814 from 12 Asian countries were included in this analysis. The estimated pooled prevalence of pediatric cataracts in Asian children is 3.78 (95% confidence interval: 2.54-5.26)/10,000 individuals with high heterogeneity (I[2] = 89.5%). The pooled prevalence by each country per 10,000 was 0.60 in Indonesia, 0.92 in Bangladesh, 1.47 in Iran, 2.01 in Bhutan, 3.45 in Laos, 3.68 in China, 4.27 in Thailand, 4.47 in India, 5.33 in Malaysia, 5.42 in Nepal, 9.34 in Vietnam, and 10.86 in Cambodia.
CONCLUSIONS: This study utilizes existing literature to identify the prevalence of cataracts in Asian children. Moreover, it highlights the need for more epidemiological studies with large sample sizes from other countries in Asia to accurately estimate the burden of disease.