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  1. Mahmoodian H, Hamiruce Marhaban M, Abdulrahim R, Rosli R, Saripan I
    Australas Phys Eng Sci Med, 2011 Apr;34(1):41-54.
    PMID: 21327594 DOI: 10.1007/s13246-011-0054-8
    The classification of the cancer tumors based on gene expression profiles has been extensively studied in numbers of studies. A wide variety of cancer datasets have been implemented by the various methods of gene selection and classification to identify the behavior of the genes in tumors and find the relationships between them and outcome of diseases. Interpretability of the model, which is developed by fuzzy rules and linguistic variables in this study, has been rarely considered. In addition, creating a fuzzy classifier with high performance in classification that uses a subset of significant genes which have been selected by different types of gene selection methods is another goal of this study. A new algorithm has been developed to identify the fuzzy rules and significant genes based on fuzzy association rule mining. At first, different subset of genes which have been selected by different methods, were used to generate primary fuzzy classifiers separately and then proposed algorithm was implemented to mix the genes which have been associated in the primary classifiers and generate a new classifier. The results show that fuzzy classifier can classify the tumors with high performance while presenting the relationships between the genes by linguistic variables.
  2. Kul E, Abdulrahim R, Bayındır F, Matori KA, Gül P
    Dent Med Probl, 2021 5 14;58(2):187-191.
    PMID: 33982454 DOI: 10.17219/dmp/126745
    BACKGROUND: If a temporary restoration is in the esthetic area and needs to be worn for a long time, the color stability of temporary materials becomes an important factor.

    OBJECTIVES: The aim of this in vitro study was to evaluate the long-term effects of various staining solutions on the color stability of different temporary materials produced with the computer-aided design and computer-aided manufacturing (CAD/CAM) technology.

    MATERIAL AND METHODS: In the study, the following materials were used: VITA CAD-Temp® (group 1); Ceramill® Temp (group 2); and Telio® CAD (group 3). Forty disk-shaped specimens (10 mm in diameter, 2 mm in thickness) of each material (N = 120) were produced with a CAD/CAM system. Staining solutions - of tea (A), of coffee (B) and cola (C) - and distilled water (D, control) were used, and color was evaluated before and after storing the samples in the solutions. Measurements were taken with a spectrophotometer and the color parameters (L*, a*, b*, and ΔE) were calculated according to the Commission internationale de l'éclairage system (CIELab). The results were evaluated with the two-way analysis of variance (ANOVA) and Tukey's tests (α = 0.05).

    RESULTS: Clinically perceivable (ΔE00 > 0.8) and statistically significant (p < 0.001) color differences were detected in all specimens. The highest ΔE00 value was found in the Ceramill Temp specimens. In addition, the highest ΔE00 values were noted for the specimens stored in cola and the coffee solution for all groups. The lowest ΔE00 value was observed for the groups stored in the tea solution.

    CONCLUSIONS: Clinically perceivable color changes were observed in all the specimens kept in the solutions. Color changes were greater for cola and coffee as compared to tea.

  3. Alshehri AA, Adebayo Irekeola A, Merae Alshahrani M, Mohammed Abdul KS, Ahmed Asiri S, Aboluluy BF, et al.
    Saudi Med J, 2024 Jul;45(7):667-674.
    PMID: 38955448 DOI: 10.15537/smj.2024.45.7.20240338
    OBJECTIVES: To ascertain the prevalence of transfusion transmissible infections (TTIs) across diverse donor groups in the Najran province. Additionally, to establish a potential association between the development of TTI and the donors' blood group, as determined by the ABO/Rh blood grouping system.

    METHODS: Blood donation data of 4120 donors, spanning from January to December 2020, were retrospectively reviewed. The blood were screened for TTI markers, including hepatitis B surface antigen (HBsAg), anti-hepatitis B core (anti-HBc), anti-hepatitis C virus (anti-HCV), anti-human immunodeficiency viruses 1 and 2 (anti-HIV1&2), anti-human T-lymphotropic virus types 1 and 2 (anti-HTLV-1&2), and syphilis antigen.

    RESULTS: Positive TTI markers were detected in 10.9% of the donors. The most detected TTI marker was anti-HBc (8.9%), followed by HBsAg (0.7%). Other markers were individually detected in <1% of the donors. Anti-HBc-positive was significantly elevated among non-Saudi blood donors. There was an association between age groups and anti-HCV (p=0.002), anti-HTLV (p=0.004) and syphilis antigen (p=0.02) markers positivity. The AB positive blood group exhibited the most positivity for TTI markers, followed by O positive blood group. Similarly, association was found between ABO group and HBsAg (p=0.01), anti-HBc (p=0.001), and anti-HCV (p<0.001) markers positivity.

    CONCLUSION: Emphasis on implementing robust screening measures for donated blood is underscored by this study. There is the need for future study to extensively evaluate TTI status to enhance our understanding of the trend in TTI.

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