MyMedR

Fulltext Barlow's Repair: Light in the Dark Tunnel: A Case Report Could Omit 'Light in A Dark Tunnel'

Mohd Alkaf AL, Simon V, Taweesak C, Abdul Rahman I

Med J Malaysia, 2015 Apr;70(2):106-7.

Barlow's disease has a complex pathology requiring reconstructive surgery. Despite the complicated surgery it holds a positive outcome. We report a successful case of Barlow's disease who underwent mitral valve reconstructive surgery at our centre. Post-operative echocardiography shows a well-functioning repaired mitral valve without significant mitral regurgitation.

Fulltext Primary lymphangiomyomatosis with chylous ascites

Abdul-Rahman I, Tay SK, Meah FE, Abdullah T

Med J Malaysia, 1994 Jun;49(2):179-81.

PMID: 8090101

Primary lymphangiomyomatosis is a benign tumour of lymphatic channels and lymph nodes, clinically manifested by chylous ascites. This disease is usually progressive and unresponsive to surgery, chemotherapy or irradiation. A case of a 36-year-old lady with chylous ascites due to underlying primary lymphangiomyomatosis is reported.

Assessment of Natural Radioactivity Levels and Radiation Hazards in Agricultural and Virgin Soil in the State of Kedah, North of Malaysia

Alzubaidi G, Hamid FB, Abdul Rahman I

ScientificWorldJournal, 2016;2016:6178103.

PMID: 27965987

The activity concentrations of naturally occurring radionuclides (226)Ra, (232)Th, and (40)K were determined in 30 agricultural and virgin soil samples randomly collected from Kedah, north of Malaysia, at a fertile soil depth of 0-30 cm. Gamma-ray spectrometry was applied using high-purity germanium (HPGe) gamma-ray detector and a PC-based MCA. The mean radioactivity concentrations of (226)Ra, (232)Th, and (40)K were found to be 102.08 ± 3.96, 133.96 ± 2.92, and 325.87 ± 9.83 Bq kg(-1), respectively, in agricultural soils and 65.24 ± 2.00, 83.39 ± 2.27, and 136.98 ± 9.76 Bq kg(-1), respectively, in virgin soils. The radioactivity concentrations in agricultural soils are higher than those in virgin soils and compared with those reported in other countries. The mean values of radium equivalent activity (Raeq), absorbed dose rates D (nGy h(-1)), annual effective dose equivalent, and external hazard index (Hex) are 458.785 Bq kg(-1), 141.62 nGy h(-1), and 0.169 mSv y(-1), respectively, in agricultural soils and 214.293 Bq kg(-1), 87.47 nGy h(-1), and 0.106 mSv y(-1), respectively, in virgin soils, with average Hex of 0.525. Results were discussed and compared with those reported in similar studies and with internationally recommended values.

Fulltext Mycotic bronchial artery aneurysmal rupture in the early stage of lung abscess: A case report

Mohd Alkaf AL, Syed Rasul SH, Abdul Rahman I

Med J Malaysia, 2016 04;71(2):96-7.

PMID: 27326956 MyJurnal

Symptomatic bronchial artery aneurysm warrants urgent intervention. It has a known association with pulmonary infection caused by Staphylococcus aureus. We hereby report an elderly lady with a ruptured left superior bronchial artery mycotic aneurysm. She was in the early stages of treatment for a left lung abscess. She had multiple episodes of haemoptysis following which she underwent a left lower lobectomy. Presentation of lung abscess with a concurrent ruptured mycotic aneurysm warrants early surgical intervention and can be curative as seen in this case.

Intracerebral haematomas after deep brain stimulation surgery in a patient with Tourette syndrome and low factor XIIIA activity

Idris Z, Ghani AR, Mar W, Bhaskar S, Wan Hassan WN, Tharakan J, et al.

J Clin Neurosci, 2010 Oct;17(10):1343-4.

PMID: 20620064 DOI: 10.1016/j.jocn.2010.01.054

A 24-year-old male patient with refractory Tourette syndrome was treated with deep brain stimulation (DBS) and developed subsequent bilateral subcortical haematomas. Additional blood tests revealed abnormalities of plasma factor XIIIA and tryptophan levels, which may be associated with Tourette syndrome. Neurosurgeons who perform DBS surgery on patients with Tourette syndrome must be aware of possible disastrous complications resulting from factor XIIIA disorders of blood haemostasis. Routine screening for this condition is not typically performed prior to surgery in these patients.

Physical and optical studies of Gd2 O2 S:Eu3+ nanophosphors by microwave irradiation and γ-irradiation methods

Rahim S, Ayob MTM, Hasim MH, Abdul Rahman I, Radiman S

Luminescence, 2019 Nov;34(7):699-706.

PMID: 31293037 DOI: 10.1002/bio.3655

Gd2 O2 S:Eu3+ nanophosphors have been successfully synthesized using microwave irradiation and γ-irradiation methods with polyvinyl pyrrolidone as a stabilizer. The physical and luminescence spectra were compared. The morphologies of both Gd2 O2 S:Eu3+ nanophosphors were in the hexagonal phase and mainly consisted of spherical nanostructures with diameters of ~90 nm and ~50 nm for both microwave irradiation and γ-irradiation methods. Upon 325 nm of ultraviolet (UV) light excitation, strong red emissions (626 nm) were observed for both methods; these emissions corresponded to the 5 D0 →7 F2 transition of Eu3+ ions. However, Gd2 O2 S:Eu3+ nanophosphors following microwave treatment showed better luminescence intensity than Gd2 O2 S:Eu3+ nanophosphors treated with γ-irradiation. This difference was attributed to the crystallinity phase and surface quenching effects of Gd2 O2 S:Eu3+ nanophosphors. The reaction mechanisms of Gd2 O2 S:Eu3+ nanophosphors in both methods are discussed in detail.

Fulltext Development of a Haddon Matrix Framework for Higher Education Pandemic Preparedness: Scoping Review and Experiences of Malaysian Universities During the COVID-19 Pandemic

Shamsir MS, Krauss SE, Ismail IA, Ab Jalil H, Johar MA, Abdul Rahman I

High Educ Policy, 2022;35(2):439-478.

PMID: 34594092 DOI: 10.1057/s41307-020-00221-x

Managing education and research during pandemics has increased in importance since the onset of epidemics such as avian flu, SARS and now CoViD-19. Successful management in times of crisis ensures business continuity and institutional survival, making preparedness preceding an impending pandemic essential. Institutions of higher education (IHEs) must maintain balance between academic continuity and preventing morbidity during a pandemic crisis. To date, however, no general pandemic preparedness frameworks exist for IHEs. The aim of this paper is to report on the development of a Haddon matrix framework for IHE pandemic preparedness based on a scoping literature review of past IHE responses including pre-, during and post-pandemic phases. First, a review of previous global responses by IHEs during past pandemics was carried out. The review findings were then collated into a new IHE-centric Haddon matrix for pandemic preparedness. The content of the matrix is then illustrated through the documented responses of Malaysian universities during the early stages of the COVID-19 pandemic. The resulting IHE Haddon matrix can be used by universities as a general guide to identify preparedness gaps and intervention opportunities for business continuity during pandemics.

An Analysis of the Radiosensitiser Applications in the Biomedical Field

Lim TS, Abdul Rahman I, Umar A, Mohd Hidzir N, Paul Arkill K, Sharif R, et al.

Curr Radiopharm, 2024 Sep 02.

PMID: 39225213 DOI: 10.2174/0118744710269842240825160247

BACKGROUND: Various types of radiosensitisers have been introduced from the past until the present day for applications in the biomedical field. However, there is a lack of understanding and comparison between the various parameters introduced in addition to a lack of consensus among researchers on the optimal radiosensitiser for applications in the biomedical field.

OBJECTIVE: This review aimed to investigate the usage of radiosensitisers in the biomedical field, determine their important parameters, and suggest radiosensitisers with potential among the analysed radiosensitisers.

RESULTS AND CONCLUSION: This review has discussed several parameters for radiosensitisers, including median lethal dose, cell survival, tumour size, cell viability, Dose Enhancement Factor (DEF), Reactive Oxygen Species (ROS) concentration, radiosensitiser production complexity, radiosensitiser administration technique, and radiosensitiser toxicity. General trends regarding the development of radiosensitisers, including the types, effectiveness, and their production complexity, have also been discussed within this review article.

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