Displaying publications 641 - 660 of 2121 in total

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  1. A hybrid method for evaluating enterprise architecture implementation
    Nikpay F, Ahmad R, Yin Kia C
    Eval Program Plann, 2017 02;60:1-16.
    PMID: 27665066 DOI: 10.1016/j.evalprogplan.2016.09.001
    Enterprise Architecture (EA) implementation evaluation provides a set of methods and practices for evaluating the EA implementation artefacts within an EA implementation project. There are insufficient practices in existing EA evaluation models in terms of considering all EA functions and processes, using structured methods in developing EA implementation, employing matured practices, and using appropriate metrics to achieve proper evaluation. The aim of this research is to develop a hybrid evaluation method that supports achieving the objectives of EA implementation. To attain this aim, the first step is to identify EA implementation evaluation practices. To this end, a Systematic Literature Review (SLR) was conducted. Second, the proposed hybrid method was developed based on the foundation and information extracted from the SLR, semi-structured interviews with EA practitioners, program theory evaluation and Information Systems (ISs) evaluation. Finally, the proposed method was validated by means of a case study and expert reviews. This research provides a suitable foundation for researchers who wish to extend and continue this research topic with further analysis and exploration, and for practitioners who would like to employ an effective and lightweight evaluation method for EA projects.
    Matched MeSH terms: Research Design*
  2. The great researcher: developing a new breed of researchers for the 21st century
    Mohd Jailani Mohd Nor, Rabiah Ahmad
    CREAM : Current Research in Malaysia (Penyelidikan Terkini di Malaysia), 2012;1(1):5-20.
    MyJurnal
    In Malaysia, all sectors are currently gearing themselves in supporting the initiatives of becoming a developed nation by the year 2020. The most important element in ensuring the success of this mission is to provide critical mass of knowledge workers to champion this cause. As such the Ministry of Higher Education Malaysia (MOHE) has established the National Higher Education Strategic Plan (NHESP), comprising seven thrusts which are very crucial in providing the much needed human capital and eco-system for this agenda. The essence of NHESP is also in line with other initiatives established by the government of Malaysia such as the National Key Results Area (NKRA) and the Government Transformation Plan (GTP). In fact MOHE has developed a systematic working model for the academia to play their role actively in driving the agenda of transforming Malaysia into a developed nation. The workforce required to spearhead the agenda for an innovation-led economy can be categorized into five different groups namely: Discoverers; Innovators; Inventors; Transformers; and Technopreneurs. It is very crucial for MOHE to develop and implement a comprehensive programme for producing a new breed of researchers that can contribute in translating government policies into a reality. This article presents the challenges and success stories in reforming the landscape of Research and Development in Malaysian universities and research institutions. The establishment of NHESP has made it possible for MOHE to systematically establish comprehensive guidelines for the management of research grants, standard for research conduct, instrument to measure research performance, and standardized reporting of research and innovation output. This new approach in the management of research at the ministry level has created positive ramifications for universities, research institutions, research management centres, and research leaders. During the first five-year cycle (2006-2010) of these research initiatives, and now into the second phase (2011-2015), positive results and outcomes have started to emerge. These results include increased in generation of articles on research findings published in reputable journals worldwide. Currently, Malaysia is recognized for achieving the world's fastest growth rate in number of journal publications. In addition, increased in number of postgraduate students, commercialization of R&D products and the establishment of Higher Institutions Centres of Excellence (HiCOE) contribute towards producing a new breed of great researchers in Malaysia. A continuing positive trend indicates that this phenomenal growth will be sustained for the next few years.
    Matched MeSH terms: Research; Research Personnel
  3. Fulltext Synthesis of jatropha curcas-based methyl ester and ethyl ester as biodiesel feedstocks
    Azhari Muhammad Syam, Robiah Yunus, Tinia Idaty Mohd. Ghazi, Choong, Thomas Shean Yaw
    Pertanika Journal of Science & Technology, 2012;20(1):165-173.
    MyJurnal
    Research on the use of Jatropha curcas triglycerides as biodiesel feedstock has received worldwide attention due to its inherent characteristics. Unlike palm oil, J. curcas oil is not edible, and thus, it will not disturb the food supply. However, to the researchers' experiences with the synthesis of J. curcas, oil-based biodiesel has shown that the fuel characteristics depend largely on the type of alcohol used as the excess reactants. Transesterification reaction is chosen for this process with sodium methoxide as the catalyst. Comparison studies on the yield of esters using methanol and ethanol, as well as the impacts on the reaction rate are discussed. The effects of reaction time and molar ratio on the reaction conversion are also examined. The determination of reaction yield is based on the conversion of triglycerides into alkyl esters as the main product. The findings are described as follows: the highest percentage yield of product is attained at 96% for methanol as an excess reactant, and this is 90% when ethanol is used. The optimum conditions of parameters are achieved at 6:1 molar ratio of alcohol to triglycerides, 50 min of reaction time and reaction temperature of 65°C for methanol and 75°C for ethanol. The biodiesel properties of both ester fuels were determined according to the existing standards for biodiesel and compared to the characteristics of diesel fuel.
    Matched MeSH terms: Research; Research Personnel
  4. Fulltext Quality of life among patients suffering from cholestatic liver disease-induced pruritus: A systematic review
    Jin XY, Khan TM
    J Formos Med Assoc, 2016 Sep;115(9):689-702.
    PMID: 27431691 DOI: 10.1016/j.jfma.2016.05.006
    A systematic assessment of literature was done to estimate the impact of pruritus on health-related quality of life among patients with cholestatic liver disease (CLD). All the articles were reviewed manually for study design, population, outcomes, and study quality. A qualitative approach was used to analyze and extract data from included studies. A total of eight studies were retrieved, of which one was a cohort study and the other seven were cross-sectional studies. Overall, it appears that the incidence of pruritus was a common complication reported by most of the studies. Among patients with CLD incidence of pruritus was 29%. Pruritus was found to have a substantial impact on patients' health-related quality of life. Greater health-related quality of life impairment was observed with increased severity of pruritus. Pruritus was found to have a significant association (p<0.05) in quality-of-life instrument domains such as role limitation-physical, role limitation-emotional, bodily pain, vitality, energy, and physical mobility. Evidence suggests that pruritus has a substantial impact on health-related quality of life among patients with CLD. More research is required to support the evidence.
    Matched MeSH terms: Research Design; Qualitative Research
  5. Fulltext Husbands’ experience with their wives’ breast cancer: a qualitative study
    Yusoff, N., Reiko Yap, K.M., Ahmad, A.
    Malaysian Journal of Public Health Medicine, 2012;12(1):31-38.
    MyJurnal
    This study aims to explore the life experience of the husbands of women who survived breast cancer for more than five years following breast removal. Basic interpretative of qualitative methodology was applied in order to construct the phenomenon of breast cancer from the perspective of husbands. This approach allowed researchers to explore in-depth the experience of husbands in facing breast cancer of their wives. Four themes were identified. These are marital
    challenges, pattern of life, supportive atmosphere and psychological defenses. Health strategies should direct the family member to the specific pathway in order to facilitate them towards the effective action of healthcare at their level. Evidence from this study is a direction for future research and health planning for better health policy.
    Matched MeSH terms: Research; Research Personnel
  6. Fulltext Does glucose-6-phosphate dehydrogenase deficiency modify the course of leprosy or its treatment
    Pettit JHS, Chin J
    Lepr Rev, 1964 Jul;35(4):149-56.
    PMID: 14177689
    In a survey of over 1,000 patients with leprosy, 47 cases ( 4.4 per cent) were found to have glucose-6-phosphate dehydrogenase deficiency. A controlled clinical study suggests that such a deficiency does not modify the overall response to therapy but may predispose to a greater tendency to leprosy reactions. All patients were receiving 600 to 800 mgm. of sulphone per week and none had a frank haemolytic anaemia.
    Matched MeSH terms: Biomedical Research*
  7. TRANSMISSION BY SNAILS OF THE SPECIES OF PHYTOPHTHORA WHICH CAUSES FOOT ROT OF PIPER NIGRUM L. IN SARAWAK
    TURNER GJ
    Nature, 1964 Jun 13;202:1133.
    PMID: 14207224
    Matched MeSH terms: Research*
  8. STUDIES ON THE HABITATS AND POPLUATION OF LEPTOTROMBIDIUM (LEPTOTROMBIDIUM) AKAMUSHI AND L. (L.) DELIENSIS IN MALAYA (ACARINA: TROMBICULIDAE)
    HUBERT AA, BAKER HJ
    Am J Hyg, 1963 Sep;78:131-42.
    PMID: 14063717
    Matched MeSH terms: Research*
  9. A TRIP TO EAST AFRICA, SAIGON, MALAYSIA FOR CARE/MEDICO, AFRICAN MEDICAL RESEARCH FOUNDATION
    PARENTE JT
    J Int Coll Surg, 1965 Sep;44:6-13.
    PMID: 14320543
    Matched MeSH terms: Biomedical Research*
  10. ABSENCE OF DI-A IN MALAYAN ABORIGINES
    CHIN J
    Nature, 1964 Mar 07;201:1039.
    PMID: 14191583
    Matched MeSH terms: Biomedical Research*
  11. Observations on delayed mating and post-coital impotence of spermatozoa in Aedes albopitus (Skuse) (Diptera : Culicidae)
    Chellappah WT
    Med J Malaysia, 1964 Sep;19:60-1.
    PMID: 14244223
    Matched MeSH terms: Research*
  12. C-Abl Inhibition; A Novel Therapeutic Target for Parkinson's Disease
    Abushouk AI, Negida A, Elshenawy RA, Zein H, Hammad AM, Menshawy A, et al.
    CNS Neurol Disord Drug Targets, 2018 Apr 26;17(1):14-21.
    PMID: 28571531 DOI: 10.2174/1871527316666170602101538
    Parkinson's disease (PD) is the most prevalent movement disorder in the world. The major pathological hallmarks of PD are death of dopaminergic neurons and the formation of Lewy bodies. At the moment, there is no cure for PD; current treatments are symptomatic. Investigators are searching for neuroprotective agents and disease modifying strategies to slow the progress of neurodegeneration. However, due to lack of data about the main pathological sequence of PD, many drug targets failed to provide neuroprotective effects in human trials. Recent evidence suggests the involvement of C-Abelson (c-Abl) tyrosine kinase enzyme in the pathogenesis of PD. Through parkin inactivation, alpha synuclein aggregation, and impaired autophagy of toxic elements. Experimental studies showed that (1) c-Abl activation is involved in neurodegeneration and (2) c-Abl inhibition shows neuroprotective effects and prevents dopaminergic neuronal' death. Current evidence from experimental studies and the first in-human trial shows that c-Abl inhibition holds the promise for neuroprotection against PD and therefore, justifies the movement towards larger clinical trials. In this review article, we discussed the role of c-Abl in PD pathogenesis and the findings of preclinical experiments and the first in-human trial. In addition, based on lessons from the last decade and current preclinical evidence, we provide recommendations for future research in this area.
    Matched MeSH terms: Research; Research Personnel
  13. Postgraduate training in psychiatry in Asia
    Isaac M, Ahmed HU, Chaturvedi SK, Hopwood MJ, Javeed A, Kanba S, et al.
    Curr Opin Psychiatry, 2018 09;31(5):396-402.
    PMID: 30015670 DOI: 10.1097/YCO.0000000000000444
    PURPOSE OF REVIEW: To understand the current situation, needs and challenges in the area of postgraduate training in psychiatry in Asia and identify implementable solutions.Leaders in psychiatric education from nine Asia Pacific countries prepared country reports, based on a suggested list of items and met for a day to discuss and identify implementable solutions to improve the current unsatisfactory status of postgraduate training in psychiatry.

    RECENT FINDINGS: Except Japan, all the other countries have a very low number of psychiatrists per 100 000 population - far lower than the global target of 10 psychiatrist per 100 000 population. The undergraduate teaching in psychiatry in majority of the countries is restricted to 20 h of lectures given during the 4-6 semester and 2-3 weeks of clinical ward placements. The duration as well as the overall quality of postgraduate training and methods of assessment and accreditation varies widely across and within countries.

    SUMMARY: Numerous gaps that need to be addressed to enhance the quality of psychiatrists trained in Asia were identified. There is a need to have uniform minimum standards of training and mechanisms of mutual support, for not only training but also academics and research activities in Asia.

    Matched MeSH terms: Research/standards
  14. Women in Computational Chemistry
    Wahab HA, Amaro RE, Cournia Z
    J Chem Inf Model, 2018 11 26;58(11):2175-2177.
    PMID: 30277769 DOI: 10.1021/acs.jcim.8b00642
    Matched MeSH terms: Research Personnel/organization & administration
  15. Science in Malaysia: Challenge for the world s oldest prime minister
    Meo SA
    J Pak Med Assoc, 2018 Oct;68(10):1427-1428.
    PMID: 30317335
    Matched MeSH terms: Biomedical Research/organization & administration*
  16. A systematic review of qualitative studies exploring peer learning experiences of undergraduate nursing students
    Nelwati, Abdullah KL, Chan CM
    Nurse Educ Today, 2018 Dec;71:185-192.
    PMID: 30293048 DOI: 10.1016/j.nedt.2018.09.018
    BACKGROUND: Peer learning experiences have been reported in previous qualitative studies, however individual findings could limit practical leverage due to small sample size. Thus it is necessary to integrate invaluable findings from various qualitative studies to consider appropriateness and acceptability of peer learning in professional nurse education.

    OBJECTIVE: To identify and synthesize qualitative evidence of peer learning experiences of undergraduate nursing students so as to understand their perceptions on peer learning experiences.

    DESIGN: A qualitative systematic review was conducted in accordance with the Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) statement.

    DATA SOURCES: Database searching was conducted on electronic databases such as Cumulative Index to Nursing and Allied Health Literature (CINAHL), Science Direct, and MEDLINE that published from 2007 to 2017.

    REVIEW METHODS: Qualitative studies were appraised using the Critical Appraisal Skills Programme (CASP). Thematic analysis was used to analyse the data using line by line coding, organising coding into descriptive themes, and interpreting further to generate new insights.

    RESULTS: Six studies were included in this review. The most common themes identified were integrated into two new insights including personal development and professional development.

    CONCLUSION: This review has revealed that peer learning experiences contribute to the learning process of undergraduate nursing students in preparing them to become professional nurses through personal development and professional development.

    Matched MeSH terms: Qualitative Research*
  17. Fulltext Do not neglect the indigenous peoples when reporting health and nutrition issues of the socio-economically disadvantaged populations in Malaysia
    Khor GL, Shariff ZM
    BMC Public Health, 2019 Dec 16;19(1):1685.
    PMID: 31842826 DOI: 10.1186/s12889-019-8055-8
    The purpose of this correspondence is to express our disappointment with the coverage of the BMC Public Health supplement: Vol 19 (4) titled "Health and Nutritional Issues Among Low Income Population in Malaysia", which neglected to include the fundamental health and nutrition issues that are adversely affecting the lives and livelihood of the indigenous peoples. The Supplement comprised 21 papers. Two of these papers included indigenous peoples as study subjects. These two papers addressed peripheral, albeit important health issues, namely visual impairment and quality of life, and not the persistent and rising health concerns impacting this population. We will provide evidence from research and reports to justify our critique that the Supplement missed the opportunity to spotlight on the serious extent of the health and nutritional deprivations of the indigenous peoples of Malaysia. As researchers of the indigenous peoples, we ought to lend our voice to the "silenced minority" by highlighting their plight in the media including scientific journals.
    Matched MeSH terms: Research Report/standards*
  18. Dataset on body weight, carapace width increment and growth band count of mud crabs, Scylla olivacea
    Ikhwanuddin M, Amin-Safwan A, Hasyima-Ismail N, Azra MN
    Data Brief, 2019 Oct;26:104477.
    PMID: 31667242 DOI: 10.1016/j.dib.2019.104477
    The present paper contains two datasets; i) the growth band count (GBC) of mud crab, Scylla olivacea collected from Setiu Wetlands, Terengganu coastal water, East coast of Peninsular Malaysia and ii) the increment sizes of body weight (BW) and carapace width (CW) of immature S. olivace after molting. The datasets presented here were associated with the research articles entitled i) "Study on carapace width growth band counts relationship of orange mud crab, S. olivacea (Herbst, 1796) from Terengganu Coastal Waters, Malaysia" (Hasyima-Ismail et al. 2017) [1] and ii) "Relationship between the carapace width and body weight increments and the confirmation of Stage 1 ovary after the molting of immature orange mud crabs, S. olivacea (Herbst, 1796), in captivity" (Amin-Safwan et al. 2019-2020) [2], and provided here as raw data of Supplementary materials. Raw datasets for GBC in the wild were generated by examination of the thin cross sectioning process of the gastric mill of S. olivacea. The GBC were measured for each individual crab wherein band counts ranged from 1 to 3. The analysis provides evidence that the GBC of the crabs can be determined through both mesocardiac and zygocardiac ossicles. This data is of importance to researchers for estimation of stock assessment and improvement of fisheries management to further improve policy. For the BW-CW increment data, a total of 135 immature crabs were sampled from Setiu Wetlands, Terengganu, Malaysia, and were introduced to limb autotomy technique in order to induced molt. Crabs were reared until successful molting and immediately prior to hardened shell, before final measurement of body weight and carapace width determination. Recorded data was analyzed by calculating the increment sizes, along with correlation and regression analysis between body weight and carapace width of mud crabs.
    Matched MeSH terms: Research; Research Personnel
  19. Fulltext Excessive smartphone usage among early adolescents: impact on social competence
    Syed Ahmad Muhajir Alhaddad Syed E, Nurul Hudani Md N, Agnis S
    Jurnal Psikologi Malaysia, 2018;32:1-11.
    The benefit mobile technology brings is not limited to learning and entertainment but it also modifies human aspect of social communication. Despite the high number of previous research available concerning smartphones, there is still a gap of research that needs to be addressed such as its effect towards social competence. As the social system becomes complex, communication technology evolves to ensure the social needs are accomplished. For this study, 236 students aged between 13-14 years old were recruited and given a set of questionnaire which comprised Mobile Phone Problem Use Scale, Social Competence Scale for Teenagers and Self Scoring Self-Control Scale. In this study, the researcher attempted to examine the effect of excessive smartphone usage on social competence with self-control as mediator. Regression analysis was used to estimate the effect between the variables. The result indicates that there is negative relationship between excessive smartphone usage and social competence. However, when self-control is tested in the model as a mediator, excessive smartphones usage was not prevalent to predict social competence. This concludes to the apparent role of self-control as a mediator. The implication of study has contributed to the practical importance and methodological aspect of studies involving social competence and self-control.
    Matched MeSH terms: Research; Research Personnel
  20. An in vitro study to evaluate the genotoxicity of value added hydroxyapatite as a bone replacement material
    Akram Hassan, Swaminathan D
    Sains Malaysiana, 2011;40.
    Hydroxyapatite (HA) used for bone replacement is one of the most active areas of ceramic biomaterials research currently. It has been used clinically for the last 20 years due to its excellent biocompatibility, osseoconduction and osseointegration. Many modifications have been done to develop a stronger, tougher and biocompatible ceramic biomaterial because pure HA is brittle. Researchers in Universiti Sains Malaysia had developed this value added HA that is stronger and less brittle compared to pure HA. The objective of this in vitro study was to evaluate the genotoxic characteristic of the value added HA based material by using Bacterial Reverse Mutation Assay (Ames test). The Bacterial Reverse Mutation Assay of HA was performed on Salmonella typhimurium strains TA98, TA100, TA1535, TA1537 and Escherichia coli strain WP2 uvrA using the preincubation method in the presence and absence of an exogenous metabolic activation system. All the bacterial tester strains treated with and without S9 Mix showed no increase of revertant colonies with increase in concentration of test substance for both the dose finding test and the main test. The number of revertant colonies was less than twice that of the solvent control for all the five bacterial strains and this was reproducible for both the dose finding test and the main test. The numbers of revertant colonies in the negative and positive controls were within the background data of our laboratory. In conclusion the results of the tests showed that the value added HA was considered to have no reverse mutagenic potential under the present test conditions.
    Matched MeSH terms: Research; Research Personnel
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