MyMedR

Fulltext Very low birth weight infants--mortality and predictive risk factors

Chye JK, Lim CT

Singapore Med J, 1999 Sep;40(9):565-70.

To determine the survival rates and risk factors associated with mortality in premature very low birth weight or VLBW (< or = 1500 grams) infants.

Matched MeSH terms: Infant, Very Low Birth Weight*

Hansenula anomala infection in a neonate

Wong AR, Ibrahim H, Van Rostenberghe H, Ishak Z, Radzi MJ

J Paediatr Child Health, 2000 Dec;36(6):609-10.

PMID: 11115044

We present an unusual neonatal fungal infection, Hansenula anomala in a very low birthweight infant who underwent abdominal surgery for an omphalocele. Despite treatment with adequate doses of amphotericin B, the yeast continued to grow from the blood culture, and was only eradicated with the use of oral ketoconazole.

Matched MeSH terms: Infant, Very Low Birth Weight

Fulltext Relevance of neonatal care in developing countries

Ho NK

Singapore Med J, 1999 Sep;40(9):558-60.

PMID: 10628240

Matched MeSH terms: Infant, Very Low Birth Weight

Fulltext Does oral lansoprazole really reduce gastric acidity in VLBW premature neonates?

Tham SY, Rogers IM, Samuel KF, Singh A, Ong KK

Med J Malaysia, 2012 Jun;67(3):284-8.

PMID: 23082418 MyJurnal

Premature neonates of very low birth weight (VLBW) whose treatment required the use of naso-gastric tube feeding were investigated. 10 infants suspected of having GERD (gastroesophageal reflux) received oral lansoprazole therapy by tube administration. 9 other infants formed a control group. In the treated group a fasting pH was determined before treatment and again after 7 days treatment. The control group was similarly assessed at an interval of 7 days. Despite acid reduction, the post-treatment pH mean of 1.31 would continue to pose a threat to the esophageal mucosa. The physiology of neonatal acid secretion is discussed to explain these findings.

Matched MeSH terms: Infant, Very Low Birth Weight

Outcomes of peripherally inserted double lumen central catheter in very low birth weight infants

Cheong SM, Totsu S, Nakanishi H, Uchiyama A, Kusuda S

J Neonatal Perinatal Med, 2016;9(1):99-105.

PMID: 27002262 DOI: 10.3233/NPM-16915054

OBJECTIVE: In order to evaluate safety and usefulness of peripherally inserted double lumen central catheter (PIDLCC) in very low birth weight (VLBW) infants, outcomes of VLBW infants who had PIDLCC was studied.

SUBJECTIVE: Thirty-nine VLBW infants who were admitted to our NICU in 2013 were retrospectively analyzed.

RESULTS: Mean birth weight and gestational age was 1042.7 gram and 28.5 weeks, respectively. Total duration of indwelling PIDLCC was 1121 days (mean 28.5+18.2 days) with 85 PIDLCCs used. Dressing at the insertion site was done twice weekly with 10% povidone iodine. Four (10.3% with mean of 48 days) infants had catheter-related blood stream infection (CRBSI), with a 3.57 infection per 1000 catheter-day. The mean for days of PIDLCC in 35 infants without CRBSI was 26.5 days. Organisms isolated were Staphylococcus epidermidis, Staphylococcus aureus and Staphylococcus capitis ureolytic. Our study showed significant difference in the duration of indwelling catheter (p = 0.023) and intraventricular hemorrhage (p = 0.043) between the CRBSI group and non-CRBSI group. Five (12.8%) infants had abnormal thyroid function test, in which two infants required thyroxine supplementation upon discharge. However, duration of PIDLCC and abnormal thyroid function test was not statistically significant (p = 0.218). One (2.5%) infant died (death was not related to CRBSI). There was no serious adverse effects secondary to PIDLCC.

CONCLUSION: It is concluded that the use and maintenance of PIDLCC is safe for VLBW infants, but close monitoring should be observed to detect early signs of infection.

Matched MeSH terms: Infant, Very Low Birth Weight

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