Displaying publications 541 - 560 of 2121 in total

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  1. Steep slope dem model construction based on the unmanned aerial vehicle(UAV) images
    Dongsheng Li, Wenfei Xi
    Sains Malaysiana, 2017;46:2119-2124.
    The DEM construction of high and steep slope has great importance to slope disaster monitoring. The conventional method used to construct high and steep slope DEM model requires larger field surveying workload. First of all, the high and steep slope image was obtained through unmanned aerial vehicle (UAV) platform; Then the SIFT algorithm is used to extract the feature points which are going to be matched accurately by using RANSAC algorithm. Finally, stereo pair splicing method is used to generate orthogonal images and construct DEM model. After comparing the DEM model with actual slope measurement result collected by total station finding, it is shown that elevation error between the DEM model constructed by unmanned aerial vehicle (UAV) and actual measurement is minimal and its efficiency is proven.
    Matched MeSH terms: Research Design
  2. Improving the quality of randomized trials in Endodontics
    Duncan HF, Nagendrababu V, Bjørndal L, Kvist T, Dummer PMH
    Int Endod J, 2020 Jun;53(6):731-732.
    PMID: 32396666 DOI: 10.1111/iej.13297
    Matched MeSH terms: Research Design
  3. Fulltext Revitalizing journal clubs: Millennial perspectives for enhancing student learning and engagement
    Rajhans V, Mohammed CA, Ve RS, Prabhu A
    Educ Health (Abingdon), 2021 7 3;34(1):22-28.
    PMID: 34213440 DOI: 10.4103/efh.EfH_69_20
    Background: Current trends in health professions education are aligned to meet the needs of the millennial learner. The aim of this study was to identify learners' perceptions of an ongoing journal club (JC) activity in the optometry curriculum and evaluate the utility and efficiency of this method in promoting student learning.

    Methods: A qualitative approach with a phenomenological research design was adopted. The perceptions of undergraduate and postgraduate optometry students about JCs were captured using focus group discussions. A narrative thematic analysis was done using the verbatim transcripts and moderator's notes. Results are reported using "consolidated criteria for reporting qualitative research" guidelines.

    Results: A total of 33 optometry students participated in the study. Data analysis revealed three major themes related to (i) The ongoing practice of JC, (ii) student perceptions of JC and its relevance in facilitating student learning, and (iii) suggestions for modification of JC for achieving optimal educational outcomes.

    Discussion: Student feedback indicates that an instructional redesigning of JC is necessary, considering the characteristics and expectations of the current generation of learners and the rapid strides made in the field of educational technology. The recommendations provided are likely to resurrect an age-old approach that still has educational relevance if blended with collaborative learning formats and appropriate technology.

    Matched MeSH terms: Qualitative Research
  4. A contrast stretching bilateral closing top-hat Otsu threshold technique for crack detection in images
    Sim KS, Kho YY, Tso CP, Nia ME, Ting HY
    Scanning, 2013 Mar-Apr;35(2):75-87.
    PMID: 22777599 DOI: 10.1002/sca.21037
    Detection of cracks from stainless steel pipe images is done using contrast stretching technique. The technique is based on an image filter technique through mathematical morphology that can expose the cracks. The cracks are highlighted and noise removal is done efficiently while still retaining the edges. An automated crack detection system with a camera platform has been successfully implemented. We compare crack extraction in terms of quality measures with those of Otsu's threshold technique and the another technique (Iyer and Sinha, 2005). The algorithm shown is able to achieve good results and perform better than these other techniques.
    Matched MeSH terms: Research Design
  5. Carbon nanomaterial properties help to enhance xylanase production from recombinant Kluyveromyces lactis through a cell immobilization method
    Abdul Manaf SA, Mohamad Fuzi SFZ, Low KO, Hegde G, Abdul Manas NH, Md Illias R, et al.
    Appl Microbiol Biotechnol, 2021 Nov;105(21-22):8531-8544.
    PMID: 34611725 DOI: 10.1007/s00253-021-11616-0
    Carbon nanomaterials, due to their catalytic activity and high surface area, have potential as cell immobilization supports to increase the production of xylanase. Recombinant Kluyveromyces lactis used for xylanase production was integrated into a polymeric gel network with carbon nanomaterials. Carbon nanomaterials were pretreated before cell immobilization with hydrochloric acid (HCl) treatment and glutaraldehyde (GA) crosslinking, which contributes to cell immobilization performance. Carbon nanotubes (CNTs) and graphene oxide (GO) were further screened using a Plackett-Burman experimental design. Cell loading and agar concentration were the most important factors in xylanase production with low cell leakage. Under optimized conditions, xylanase production was increased by more than 400% compared to free cells. Immobilized cell material containing such high cell densities may exhibit new and unexplored beneficial properties because the cells comprise a large fraction of the component. The use of carbon nanomaterials as a cell immobilization support along with the entrapment method successfully enhances the production of xylanase, providing a new route to improved bioprocessing, particularly for the production of enzymes. KEY POINTS: • Carbon nanomaterials (CNTs, GO) have potential as cell immobilization supports. • Entrapment in a polymeric gel network provides space for xylanase production. • Plackett-Burman design screen for the most important factor for cell immobilization.
    Matched MeSH terms: Research Design
  6. My precarious career in photosynthesis: a roller-coaster journey into the fascinating world of chloroplast ultrastructure, composition, function and dysfunction
    Chow WS
    Photosynth Res, 2021 Aug;149(1-2):5-24.
    PMID: 33543372 DOI: 10.1007/s11120-021-00818-2
    Despite my humble beginnings in rural China, I had the good fortune of advancing my career and joining an international community of photosynthesis researchers to work on the 'light reactions' that are a fundamental process in Nature. Along with supervisors, mentors, colleagues, students and lab assistants, I worked on ionic redistributions across the photosynthetic membrane in response to illumination, photophosphorylation, forces that regulate the stacking of photosynthetic membranes, the composition of components of the photosynthetic apparatus during acclimation to the light environment, and the failure of the photosynthetic machinery to acclimate to too much light or even to cope with moderate light due to inevitable photodamage. These fascinating underlying mechanisms were investigated in vitro and in vivo. My career path, with its ups and downs, was never secure, but the reward of knowing a little more of the secret of Nature offset the job uncertainty.
    Matched MeSH terms: Research Personnel/history*; Research Report/history*
  7. Fulltext Impact of the COVID-19 Pandemic on Cancer Researchers in 2020: A Qualitative Study of Events to Inform Mitigation Strategies
    Fox L, Beyer K, Rammant E, Morcom E, Van Hemelrijck M, Sullivan R, et al.
    Front Public Health, 2021;9:741223.
    PMID: 34966713 DOI: 10.3389/fpubh.2021.741223
    Introduction: The COVID-19 pandemic has had an unprecedented impact on global health systems and economies. With ongoing and future challenges posed to the field due to the pandemic, re-examining research priorities has emerged as a concern. As part of a wider project aiming to examine research priorities, here we aimed to qualitatively examine the documented impacts of the COVID-19 pandemic on cancer researchers. Materials and Methods: We conducted a literature review with the aim of identifying non-peer-reviewed journalistic sources and institutional blog posts which qualitatively documented the effects of the COVID-19 pandemic on cancer researchers. We searched on 12th January 2021 using the LexisNexis database and Google, using terms and filters to identify English-language media reports and blogs, containing references to both COVID-19 and cancer research. The targeted search returned 751 results, of which 215 articles met the inclusion criteria. These 215 articles were subjected to a conventional qualitative content analysis, to document the impacts of the pandemic on the field of cancer research. Results: Our analysis yielded a high plurality of qualitatively documented impacts, from which seven categories of direct impacts emerged: (1) COVID measures halting cancer research activity entirely; (2) COVID measures limiting cancer research activity; (3) forced adaptation of research protocols; (4) impacts on cancer diagnosis, cases, and services; (5) availability of resources for cancer research; (6) disruption to the private sector; and (7) disruption to supply chains. Three categories of consequences from these impacts also emerged: (1) potential changes to future research practice; (2) delays to the progression of the field; and (3) potential new areas of research interest. Discussion: The COVID-19 pandemic had extensive practical and economic effects on the field of cancer research in 2020 that were highly plural in nature. Appraisal of cancer research strategies in a post-COVID world should acknowledge the potential for substantial limitations (such as on financial resources, limited access to patients for research, decreased patient access to cancer care, staffing issues, administrative delays, or supply chain issues), exacerbated cancer disparities, advances in digital health, and new areas of research related to the intersection of cancer and COVID-19.
    Matched MeSH terms: Qualitative Research
  8. Fulltext Designing the next generation of implementation research training for learners in low- and middle-income countries
    Penkunas MJ, Chong SY, Rhule ELM, Berdou E, Allotey P
    Global Health, 2021 06 21;17(1):63.
    PMID: 34154605 DOI: 10.1186/s12992-021-00714-3
    Efficacious health interventions tested through controlled trials often fail to show desired impacts when implemented at scale. These challenges can be particularly pervasive in low- and middle-income settings where health systems often lack the capacity and mechanisms required for high-quality research and evidence translation. Implementation research is a powerful tool for identifying and addressing the bottlenecks impeding the success of proven health interventions. Implementation research training initiatives, although growing in number, remain out of reach for many investigators in low- and middle-income settings, who possess the knowledge required to contextualize challenges and potential solutions in light of interacting community- and system-level features. We propose a realigned implementation research training model that centers on team-based learning, tailored didactic opportunities, learning-by-doing, and mentorship.
    Matched MeSH terms: Research Personnel
  9. Fulltext Challenges and Research Priorities for Dementia Care in Malaysia from the Perspective of Health and Allied Health Professionals
    Rosli R, Goodson M, Tan MP, Mohan D, Reidpath D, Allotey P, et al.
    Int J Environ Res Public Health, 2021 10 20;18(21).
    PMID: 34769530 DOI: 10.3390/ijerph182111010
    Few studies to date have evaluated dementia care in Malaysia, and the focus of studies has primarily been on epidemiological and laboratory research. In this study, we aimed to identify potential challenges for the delivery of dementia care in Malaysia and priorities for research and enhancing existing dementia care. This study used thematic analysis to evaluate the open and focus group workshop discussions guided by semi-structured questions. Triangulation of the collected data (sticky notes, collated field notes, and transcripts of discussions) was achieved through stakeholder consensus agreement during a workshop held in 2017. Five main themes as priorities for dementia care were identified: (1) availability of a valued multi-disciplinary care service, (2) accessibility of training to provide awareness, (3) the functionality of the governance in establishing regulation and policy to empower care services, (4) perceived availability and accessibility of research data, and (5) influence of cultural uniqueness. The findings of this study seek to enhance existing dementia care in Malaysia but have potential application for other low and middle-income countries with a similar social and health care set up. The constructed relationship between themes also tries to tackle the challenges in a more efficient and effective manner, as none of these aforementioned issues are standalone challenges. In addition, we demonstrated how a carefully constructed workshop with defined aims and objectives can provide a useful analysis tool to evaluate health and social care challenges in a multidisciplinary forum.
    Matched MeSH terms: Research
  10. Fulltext Impact of sustainable project management on project plan and project success of the manufacturing firm: Structural model assessment
    Chow TC, Zailani S, Rahman MK, Qiannan Z, Bhuiyan MA, Patwary AK
    PLoS One, 2021;16(11):e0259819.
    PMID: 34818357 DOI: 10.1371/journal.pone.0259819
    This study has aimed to investigate the impact of sustainable project management on sustainable project planning and success in manufacturing firms. Data was collected from project management professionals in a manufacturing firm in Malaysia. A total of 231 responses were analyzed using the partial least square (PLS) method. The findings revealed that sustainable project management has a significant impact on sustainable project success and sustainable project planning. Sustainable project planning is positively correlated with sustainable project success. The results also indicated that sustainable project planning mediates the effect of sustainable project management on sustainable project success. The findings have significant insight into the body of knowledge of the project life cycle and indicated that sustainable project planning is a crucial tool attributed to project management towards the project success of the manufacturing firm. The results can be used as a guideline for organizations, providing direction in project management to achieve sustainable development for business.
    Matched MeSH terms: Research Design
  11. Fulltext A functional pipeline framework for landmark identification on 3D surface extracted from volumetric data
    Zheng P, Belaton B, Liao IY, Rajion ZA
    PLoS One, 2017;12(11):e0187558.
    PMID: 29121077 DOI: 10.1371/journal.pone.0187558
    Landmarks, also known as feature points, are one of the important geometry primitives that describe the predominant characteristics of a surface. In this study we proposed a self-contained framework to generate landmarks on surfaces extracted from volumetric data. The framework is designed to be a three-fold pipeline structure. The pipeline comprises three phases which are surface construction, crest line extraction and landmark identification. With input as a volumetric data and output as landmarks, the pipeline takes in 3D raw data and produces a 0D geometry feature. In each phase we investigate existing methods, extend and tailor the methods to fit the pipeline design. The pipeline is designed to be functional as it is modularised to have a dedicated function in each phase. We extended the implicit surface polygonizer for surface construction in first phase, developed an alternative way to compute the gradient of maximal curvature for crest line extraction in second phase and finally we combine curvature information and K-means clustering method to identify the landmarks in the third phase. The implementations are firstly carried on a controlled environment, i.e. synthetic data, for proof of concept. Then the method is tested on a small scale data set and subsequently on huge data set. Issues and justifications are addressed accordingly for each phase.
    Matched MeSH terms: Research Design
  12. Internal model control for industrial wireless plant using WirelessHART hardware-in-the-loop simulator
    Tran CD, Ibrahim R, Asirvadam VS, Saad N, Sabo Miya H
    ISA Trans, 2018 Apr;75:236-246.
    PMID: 29478749 DOI: 10.1016/j.isatra.2017.12.010
    The emergence of wireless technologies such as WirelessHART and ISA100 Wireless for deployment at industrial process plants has urged the need for research and development in wireless control. This is in view of the fact that the recent application is mainly in monitoring domain due to lack of confidence in control aspect. WirelessHART has an edge over its counterpart as it is based on the successful Wired HART protocol with over 30 million devices as of 2009. Recent works on control have primarily focused on maintaining the traditional PID control structure which is proven not adequate for the wireless environment. In contrast, Internal Model Control (IMC), a promising technique for delay compensation, disturbance rejection and setpoint tracking has not been investigated in the context of WirelessHART. Therefore, this paper discusses the control design using IMC approach with a focus on wireless processes. The simulation and experimental results using real-time WirelessHART hardware-in-the-loop simulator (WH-HILS) indicate that the proposed approach is more robust to delay variation of the network than the PID.
    Matched MeSH terms: Research
  13. Promoting Ethics and Integrity in Management Academic Research: Retraction Initiative
    Ayodele FO, Yao L, Haron H
    Sci Eng Ethics, 2019 04;25(2):357-382.
    PMID: 29441445 DOI: 10.1007/s11948-017-9941-z
    In the management academic research, academic advancement, job security, and the securing of research funds at one's university are judged mainly by one's output of publications in high impact journals. With bogus resumes filled with published journal articles, universities and other allied institutions are keen to recruit or sustain the appointment of such academics. This often places undue pressure on aspiring academics and on those already recruited to engage in research misconduct which often leads to research integrity. This structured review focuses on the ethics and integrity of management research through an analysis of retracted articles published from 2005 to 2016. The study employs a structured literature review methodology whereby retracted articles published between 2005 and 2016 in the field of management science were found using Crossref and Google Scholar. The searched articles were then streamlined by selecting articles based on their relevance and content in accordance with the inclusion criteria. Based on the analysed retracted articles, the study shows evidence of ethical misconduct among researchers of management science. Such misconduct includes data falsification, the duplication of submitted articles, plagiarism, data irregularity and incomplete citation practices. Interestingly, the analysed results indicate that the field of knowledge management includes the highest number of retracted articles, with plagiarism constituting the most significant ethical issue. Furthermore, the findings of this study show that ethical misconduct is not restricted to a particular geographic location; it occurs in numerous countries. In turn, avenues of further study on research misconduct in management research are proposed.
    Matched MeSH terms: Research Personnel/ethics*; Ethics, Research*
  14. Fulltext Review of context-based similarity measure for categorical data
    Nurul Adzlyana, M.S., Rosma, M.D., Nurazzah, A.R.
    Pertanika Journal of Science & Technology, 2017;25(2):619-630.
    MyJurnal
    Data mining processes such as clustering, classification, regression and outlier detection are developed based on similarity between two objects. Data mining processes of categorical data is found to be most challenging. Earlier similarity measures are context-free. In recent years, researchers have come up with context-sensitive similarity measure based on the relationships of objects. This paper provides an in-depth review of context-based similarity measures. Descriptions of algorithm for four context-based similarity measure, namely Association-based similarity measure, DILCA, CBDL and the hybrid context-based similarity measure, are described. Advantages and limitations of each context-based similarity measure are identified and explained. Context-based similarity measure is highly recommended for data-mining tasks for categorical data. The findings of this paper will help data miners in choosing appropriate similarity measures to achieve more accurate classification or clustering results.
    Matched MeSH terms: Research Personnel
  15. Using Surplus Embryos and Research Embryos in Stem Cell Research: Ethical Viewpoints of Buddhist, Hindu and Catholic Leaders in Malaysia on the Permissibility of Research
    Sivaraman MAF
    Sci Eng Ethics, 2018 02;24(1):129-149.
    PMID: 28281154 DOI: 10.1007/s11948-017-9893-3
    The sources of embryos for Embryonic Stem Cell Research (ESCR) include surplus embryos from infertility treatments, and research embryos which are created solely for an ESCR purpose. The latter raises more ethical concerns. In a multi-religious country like Malaysia, ethical discussions on the permissibility of ESCR with regard to the use surplus and research embryos are diversified. Malaysia has formulated guidelines influenced by the national fatwa ruling which allows the use of surplus embryos in ESCR. Input from other main religions is yet to be documented. In light of this, this study addresses (i) the ethical viewpoints of Buddhist, Hindu and Catholic leaders on the permissibility of using surplus and research embryos; and (ii) the moral standpoints of religious leaders towards attaining a consensus on the practice of ESCR in Malaysia. Responses from the religious leaders were obtained via semi-structured, face-to-face interviews. The findings show that generally the Buddhist and Hindu leaders approve the use of surplus embryos. Their responses on the creation of research embryos for ESCR are varied. Meanwhile, the Catholic leaders distinctively objected to ESCR regardless of the embryo sources, referring to it as the destruction of life. Taking into account the diverse views, this study explores the response of the religious leaders for a general consensus wherever possible. The ethical discourse surrounding ESCR in a multi-religious setting offers new perspective, which needs to be explored in a broader global community.
    Matched MeSH terms: Embryo Research/ethics*; Stem Cell Research/ethics*
  16. Fulltext Underwater Turbulence Detection Using Gated Wavefront Sensing Technique
    Bi Y, Xu X, Chua SY, Chow EMT, Wang X
    Sensors (Basel), 2018 Mar 07;18(3).
    PMID: 29518889 DOI: 10.3390/s18030798
    Laser sensing has been applied in various underwater applications, ranging from underwater detection to laser underwater communications. However, there are several great challenges when profiling underwater turbulence effects. Underwater detection is greatly affected by the turbulence effect, where the acquired image suffers excessive noise, blurring, and deformation. In this paper, we propose a novel underwater turbulence detection method based on a gated wavefront sensing technique. First, we elaborate on the operating principle of gated wavefront sensing and wavefront reconstruction. We then setup an experimental system in order to validate the feasibility of our proposed method. The effect of underwater turbulence on detection is examined at different distances, and under different turbulence levels. The experimental results obtained from our gated wavefront sensing system indicate that underwater turbulence can be detected and analyzed. The proposed gated wavefront sensing system has the advantage of a simple structure and high detection efficiency for underwater environments.
    Matched MeSH terms: Research Design
  17. Fulltext Establishing a Core Domain Set for early-phase clinical trials of electrical stimulation interventions for tinnitus in adults: protocol for an online Delphi study
    Labree B, Hoare DJ, Fackrell K, Hall DA, Gascoyne LE, Sereda M
    Trials, 2022 Dec 21;23(1):1039.
    PMID: 36539777 DOI: 10.1186/s13063-022-07020-2
    BACKGROUND: Tinnitus is the awareness of a sound in the ear or head in the absence of an external source. It affects around 10-15% of people and current treatment options are limited. Experimental treatments include various forms of electrical stimulation of the brain. Currently, there is no consensus on the outcomes that should be measured when investigating the efficacy of this type of intervention for tinnitus. This study seeks to address this by establishing a Core Domain Set: a common standard of what specific tinnitus-related complaints are critical and important to assess in all clinical trials of electrical stimulation-based interventions for tinnitus.

    METHODS: A two-round online survey will be conducted, followed by a stakeholder consensus meeting to identify a Core Domain Set. Participants will belong to one of two stakeholder groups: healthcare users with lived experience of tinnitus, and professionals with relevant clinical, commercial, or research experience.

    DISCUSSION: This study will establish a Core Domain Set for the evaluation of electrical stimulation-based interventions for tinnitus via an e-Delphi study. The resulting Core Domain Set will act as a minimum standard for reporting in future clinical trials of electrical stimulation interventions for tinnitus. Standardisation will facilitate comparability of research findings.

    Matched MeSH terms: Research Design
  18. Fulltext In-Depth Review of Augmented Reality: Tracking Technologies, Development Tools, AR Displays, Collaborative AR, and Security Concerns
    Syed TA, Siddiqui MS, Abdullah HB, Jan S, Namoun A, Alzahrani A, et al.
    Sensors (Basel), 2022 Dec 23;23(1).
    PMID: 36616745 DOI: 10.3390/s23010146
    Augmented reality (AR) has gained enormous popularity and acceptance in the past few years. AR is indeed a combination of different immersive experiences and solutions that serve as integrated components to assemble and accelerate the augmented reality phenomena as a workable and marvelous adaptive solution for many realms. These solutions of AR include tracking as a means for keeping track of the point of reference to make virtual objects visible in a real scene. Similarly, display technologies combine the virtual and real world with the user's eye. Authoring tools provide platforms to develop AR applications by providing access to low-level libraries. The libraries can thereafter interact with the hardware of tracking sensors, cameras, and other technologies. In addition to this, advances in distributed computing and collaborative augmented reality also need stable solutions. The various participants can collaborate in an AR setting. The authors of this research have explored many solutions in this regard and present a comprehensive review to aid in doing research and improving different business transformations. However, during the course of this study, we identified that there is a lack of security solutions in various areas of collaborative AR (CAR), specifically in the area of distributed trust management in CAR. This research study also proposed a trusted CAR architecture with a use-case of tourism that can be used as a model for researchers with an interest in making secure AR-based remote communication sessions.
    Matched MeSH terms: Research Personnel
  19. Fulltext Experience of Pharmacists with Anti-Cancer Medicine Shortages in Pakistan: Results of a Qualitative Study
    Shukar S, Zahoor F, Omer S, Awan SE, Yang C, Fang Y
    Int J Environ Res Public Health, 2022 Dec 06;19(23).
    PMID: 36498446 DOI: 10.3390/ijerph192316373
    This study aimed to examine the current situation of anti-cancer drug shortages in Pakistan, namely its determinants, impacts, adopted mitigation strategies, and proposed solutions. Qualitative semi-structured, in-depth interviews were conducted with 25 pharmacists in oncology hospitals in Pakistan from August to October 2021. Data were collected in person and online, recorded, and subjected to inductive thematic analysis after being transcribed verbatim. Most participants experienced anti-cancer drug shortages that increased during the pandemic. Etoposide, paclitaxel, vincristine, dacarbazine, and methotrexate were frequently short. Important causes included the compromised role of regulatory authorities, lack of local production, and inventory mismanagement. The impacts were delayed/suboptimal treatment and out-of-pocket costs for patients, patients' prioritization, increased workload, negative work environment, and patients' trust issues for pharmacists. The participants proposed that a cautious regulator's role is needed to revise policies for all stakeholders and support all stakeholders financially at their level to increase access to these medicines. Based on the outcomes, it is clear that anti-cancer medicine shortages are a current issue in Pakistan. Governmental authorities need to play a role in revising policies for all levels of the drug supply chain and promoting local production of these drugs. Stakeholders should also collaborate and manage inventory.
    Matched MeSH terms: Qualitative Research
  20. Composition optimization of PLA/PPC/HNT nanocomposites for mandibular fixation plate using single-factor experimental design
    Haneef INHM, Buys YF, Shaffiar NM, Abdul Hamid AM, Shaharuddin SIS, Fitriani
    J Mech Behav Biomed Mater, 2022 Nov;135:105423.
    PMID: 36087517 DOI: 10.1016/j.jmbbm.2022.105423
    The need to overcome the secondary surgery to remove implanted metal fixation plate leads to the idea of replacing the material with degradable bionanocomposite. In this research, polylactic acid/polypropylene (PLA/PPC) blends incorporated with halloysite nanotubes (HNT) (0-6 wt %) were considered as the candidate material for mandibular fixation plate. A single-factor design using Design Expert software was used to determine 20 different compositions of PLA/PPC/HNT nanocomposites and their mechanical properties were then measured. The optimization of the PLA/PPC/HNT nanocomposite composition was performed based on the nanocomposite's response to Young's modulus, tensile strength, and elongation at break. Further analysis suggested an optimum composition of 92.5/7.5 PLA/PPC with 6 wt % of HNT. The statistical results predicted that there was a 71.7% possibility that the proposed nanocomposite would have the following mechanical properties: Young's modulus of 2.18 GPa, a tensile strength of 64.16 MPa, and an elongation at break of 106.53%.
    Matched MeSH terms: Research Design
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