MyMedR

Fulltext Treatment of tetanus neonatorum in a rural setting

Yong YF

Med J Malaysia, 1983 Mar;38(1):74-6.

Tetanus, especially tetanus neonatorum (T.N.) continues to be a significant medical and social problem in the developing countries. The case mortality rate remains very high even in the 'developed' countries, varying from 60-80 percent in various reports, and even higher in the case of tetanus neonatorum. Sanders et al had introduced the method of intrathecal injection of antitetanus serum (ATS) in 1976 and have achieved very encouraging results. As the conventional treatment of tetanus neonatorum had achieved very poor result, even in the very sophisticated centres, a case of tetanus neonatorum admitted to Cottage Hospital Semporna in Sabah had been treated with intrathecal ATS since June 1982. This paper reviews the results of this new approach to tetanus neonatorum treatment as compared to cases treated conventionally.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases/therapy*

The management of neonatal tetanus

Lee EL, Khoo BH, Lam KL

Med J Malaysia, 1978 Mar;32(3):220-4.

PMID: 683047

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases/therapy*

Neonatal narcotic drug withdrawal syndrome

Khoo BH

Med J Malaysia, 1978 Jun;32(4):297-301.

PMID: 732626

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases/diagnosis*

Group B streptococcal infection in the newborn

Kwan PW, Khoo BH, Lam KL, Puthucheary SD

Med J Malaysia, 1979 Sep;34(1):71-5.

PMID: 396463

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases*

Fulltext The expectant management of a rare neonatal disease: transient neonatal myasthenia gravis

Masra F, Ishak S, Cheah FC

Turk J Pediatr, 2023;65(2):321-325.

PMID: 37114697 DOI: 10.24953/turkjped.2022.717

BACKGROUND: Transient neonatal myasthenia gravis (TNMG) is an acquired disease which occurs in 10 to 20% of infants born to a mother with myasthenia gravis. Even though it is a self-limiting disorder, it may potentially be life-threatening if prompt diagnosis is not made, and expedient supportive respiratory management is not initiated when required.

CASE: Here we describe three infants with TNMG. Two of them developed symptoms of TNMG within 24 hours of life, but one developed symptoms at 43 hours of life. One of the patients had an atypical form of TNMG with contracture and hypotonia. The other two infants survived a typical form of TNMG with hypotonia and poor sucking. All cases resolved spontaneously by one to two weeks of life with conservative management.

CONCLUSIONS: Infants born to mothers with myasthenia gravis need to be monitored closely for symptoms of TNMG for the first 48 to 72 hours of life. However, the majority of infants with TNMG traverse a benign course and resolve spontaneously with expectant care.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases*

Risk factors of necrotising enterocolitis among 28-34 weeks preterm neonates at a Tertiary Care Hospital, East Java, Indonesia

Corebima BIRV, Handono K, Barlianto W, Santosaningsih D, Rohsiswatmo R, Sulistijono E, et al.

Med J Malaysia, 2023 Jul;78(4):458-465.

PMID: 37518912

INTRODUCTION: Necrotising enterocolitis (NEC) is a serious health problem primarily affects preterm and very low birthweight (VLBW) infants. However, the pathomechanism of NEC remains elusive. This study aimed to analyse the risk factors for NEC among preterm neonates in East Java, Indonesia.

MATERIALS AND METHODS: A single-centre, prospective, casecontrol study involving 32 subjects of preterm neonates was conducted at a tertiary care hospital in Malang, East Java, Indonesia between January to June 2022. A total of 15 preterm neonates with NEC and 17 preterm neonates without NEC were enrolled in this study. Data on demographic, clinical and laboratory findings were collected. Multiple logistic regression test was performed to analyse the risk factors for NEC development. Further profiling within 15 subjects with NEC, i.e., NEC grade ≥ II, were conducted to collect systemic, abdominal, laboratory, abdominal x-ray (AXR) and blood culture findings.

RESULTS: The risk factors related to NEC development in preterm infants were multi-morbidity (adjusted OR = 11.96; 95% CI 1.85 168.38; p = 0.046), antibiotic exposure (OR = 15.95; 95% CI 1.54 165.08; p = 0.020) and requiring advanced neonatal resuscitation at birth (OR = 10.04; 95% CI 1.09 92.11; p = 0.041). Further profiling within NEC cohorts highlighted respiratory distress (86.7%), (oro)gastric retention (80.0%), thrombocytopenia (53.3%), gastrointestinal dilatation in AXR (53.3%), and positive blood culture Klebsiella pneumoniae (40.0%) were most common findings.

CONCLUSION: Preterm neonates with multimorbidity, prolonged antibiotic exposure, and requiring advanced resuscitation at birth were more likely to develop NEC. Early detection of the risk factors and determinant factors for survival may help to improve the clinical outcome.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases*

The weights of Malaysian infants up to one year

Dugdale AE

Med J Malaya, 1969 Jun;23(4):244-6.

PMID: 4242167

Matched MeSH terms: Infant, Newborn*

The fast moving haemoglobin component in healthy newborn babies in Malaya

Lie-Injo LE

Med J Malaya, 1961 Dec;16:107-14.

PMID: 14465150

Matched MeSH terms: Infant, Newborn/blood

Occult primary spontaneous pneumothorax

Tai, Yong-Ting, Tong, Chin-Voon

International e-Journal of Science, Medicine & Education, 2017;11(2):30-33.

MyJurnal

We report a case of occult primary spontaneous
pneumothorax in a 30 years-old woman. She
developed symptoms and signs that were suggestive of
pneumothorax. However, chest radiograph failed to
reveal pneumothorax. Therefore, we proceeded with
computed tomography (CT) thorax which revealed
significantly moderate right pneumothorax. The
diagnostic approach and the management of this case
are discussed.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases

Fulltext Infant with a sudden, large, post-extubation subglottic cyst

Asha'ari ZA, Suhaimi Y, Fadzil A, Zihni M

Malays J Med Sci, 2012 Oct;19(4):84-7.

PMID: 23613654 MyJurnal

Acquired subglottic cyst in infancy is almost always associated with episodes of early life intubation. Most cases typically presented late, usually days to months after extubation. We report a case of a subglottic cyst with different presentation than the norm. This case highlights that subglottic cyst can present acutely, and rapidly enlarging soon after the airway extubation. As the management of a large subglottic cyst can be challenging, a close observation for early diagnosis and intervention are recommended post extubation in the high-risk cases, such as in the premature infant.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases

Newborn seizure detection based on heart rate variability

Malarvili MB, Mesbah M

IEEE Trans Biomed Eng, 2009 Nov;56(11):2594-603.

PMID: 19628449 DOI: 10.1109/TBME.2009.2026908

In this paper, we investigate the use of heart rate variability (HRV) for automatic newborn seizure detection. The proposed method consists of a sequence of processing steps, namely, obtaining HRV from the ECG, extracting a discriminating HRV feature set, selecting an optimal subset from the full feature set, and, finally, classifying the HRV into seizure/nonseizure using a supervised statistical classifier. Due to the fact that HRV signals are nonstationary, a set of time-frequency features from the newborn HRV is proposed and extracted. In order to achieve efficient HRV-based automatic newborn seizure detection, a two-phase wrapper-based feature selection technique is used to select the feature subset with minimum redundancy and maximum class discriminability. Tested on ECG recordings obtained from eight newborns with identified EEG seizure, the proposed HRV-based neonatal seizure detection algorithm achieved 85.7% sensitivity and 84.6% specificity. These results suggest that the HRV is sensitive to changes in the cardioregulatory system induced by the seizure, and therefore, can be used as a basis for an automatic seizure detection.

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases/diagnosis*; Infant, Newborn, Diseases/physiopathology

Postoperative Spontaneous Gastric Perforation in a Ruptured Exomphalos: A Case Report

Raa H, As R, Tp G, A S

J Neonatal Surg, 2016 04 10;5(2):19.

PMID: 27123403

Spontaneous gastric perforation is a rare entity in neonates. We report a case of spontaneous gastric perforation in a neonate operated for in-utero rupture of omphalocele.

Matched MeSH terms: Infant, Newborn

Fulltext Use of steroids sparingly especially in children

Ng LF

Med J Malaysia, 1985 Jun;40(2):142.

PMID: 3834286

Matched MeSH terms: Infant, Newborn

Birth trauma and nasal septal deformity in neonates

Saim L, Said H

J Singapore Paediatr Soc, 1992;34(3-4):199-204.

PMID: 1305661

The prevalence of nasal septal deformity and its relationship with the different types and difficulty of delivery were studied in a randomised group of newborns at the Maternity Hospital Kuala Lumpur between 1st November 1989 to 31st January 1990. Out of a total of 674 noses examined using the otoscope, 147 (21.8%) were found to have nasal septal deformity. There was no significant difference in the prevalence of nasal septal deformity in the different types of delivery. There was also no significant increase in the prevalence of nasal septal deformity with increasing degree of difficulty of the delivery. Therefore, we cannot then attribute parturition pressures or birth trauma as the etiology of these congenital nasal septal deformity. Nevertheless a policy of routine screening in view of early correction is advocated to decrease the morbidity associated with this deformity in newborns and children.

Matched MeSH terms: Infant, Newborn

Fulltext Sickle cell anaemia in pregnancy: a case report

Rachagan SP, Raman S, Cherian R

Med J Malaysia, 1984 Sep;39(3):243-5.

PMID: 6544928

To our knowledge, sickle cell anaemia in pregnancy has not been reported in Malaysia. We describe here such a case with emphasis on modern methods of management.

Matched MeSH terms: Infant, Newborn

Congenital duplication of the gall bladder: review of the literature and report of a case

Ramanathan T

Med J Malaya, 1971 Jun;25(4):305-6.

PMID: 4261308

Matched MeSH terms: Infant, Newborn

Fulltext Cutis Marmorata Telangiectatica Congenita Associated with Hemiatrophy

Leung AKC, Lam JM, Leong KF

Case Rep Pediatr, 2020;2020:8813809.

PMID: 33101749 DOI: 10.1155/2020/8813809

Cutis marmorata telangiectatica congenita is characterized by the presence of a bluish-purple reticulated cutaneous vascular network on the skin intermixed with telangiectasia and occasionally prominent veins at birth. Areas of the skin within the reticulated cutaneous vascular network may be normal, erythematous, atrophic, and, at times, ulcerated. Areas of ulcerations and focal cutaneous and subcutaneous atrophy occasionally occur resulting in body asymmetry. On the other hand, cutaneous and subcutaneous atrophy, extensive and severe enough leading to hemiatrophy, of the entire limb is rare. A search of the English literature revealed only eight documented cases to which we are adding two more cases.

Matched MeSH terms: Infant, Newborn

Towards a new role for the infant food industry

Abraham SCE

Family Practitioner, 1977;2:61-63.

Matched MeSH terms: Infant, Newborn

Optimising bone health among older people with hip fractures and co-existing advanced chronic kidney disease

Ong T, Yong BKA, Shouter T, Shahrokhi N, Sahota O

Eur Geriatr Med, 2020 08;11(4):635-638.

PMID: 32488688 DOI: 10.1007/s41999-020-00340-z

PURPOSE: Patients with a hip fracture and co-existing advanced chronic kidney disease (CKD) are at risk of further fractures due to either CKD-mineral bone disease or osteoporosis.

METHODS: An analysis of a hospital's hip fracture service registry of patients ≥ 60 years with CKD stage 4 (15-29 ml/min/1.73m2) or stage 5 (

Matched MeSH terms: Infant, Newborn

Fulltext Homozygous Southeast Asian Ovalocytosis in five live-born neonates

Lavinya AA, Razali RA, Razak MA, Mohamed R, Moses EJ, Soundararajan M, et al.

Haematologica, 2021 06 01;106(6):1758-1761.

PMID: 33179475 DOI: 10.3324/haematol.2020.268581

Not available.

Matched MeSH terms: Infant, Newborn

Displaying publications 21 - 40 of 1802 in total