Displaying publications 21 - 40 of 319 in total

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  1. Chua KB, Kasri AR
    Virol Sin, 2011 Aug;26(4):221-8.
    PMID: 21847753 DOI: 10.1007/s12250-011-3195-8
    Hand foot and mouth disease is a febrile sickness complex characterized by cutaneous eruption (exanthem) on the palms and soles with simultaneous occurrence of muco-cutanous vesiculo-ulcerative lesions (enanthem) affecting the mouth. The illness is caused by a number of enteroviruses with coxsackievirus A16 and enterovirus 71 as the main causative agents. Human enterovirus 71 (EV71) belongs to the species Human enterovirus A under the genus Enterovirus within the family Picornaviridae. EV71 has been associated with an array of clinical diseases including hand foot and mouth disease (HFMD), aseptic meningitis, encephalitis and poliomyelitis-like acute flaccid paralysis. A large outbreak of HFMD due to highly neurovirulent EV71 emerged in Malaysia in 1997, and caused 41 deaths amongst young children. In late 2000, a recurrence of an outbreak of HFMD occurred in Malaysia with 8 fatalities in peninsular Malaysia. Outbreak of HFMD due to EV71 recurred in 2003 with an unknown number of cases and mortalities. A similar outbreak of HFMD with 2 recorded deaths in young children occurred in peninsular Malaysia in late 2005 and this was followed by a larger outbreak in Sarawak (Malaysian Borneo) with 6 reported fatalities in the early part of 2006. The current on-going outbreak of HFMD started in peninsular Malaysia in epidemiological week 12 of 2010. As with other HFMD outbreaks in Malaysia, both EV71 and CA16 were the main aetiological viruses isolated. In similarity with the HFMD outbreak in 2005, the isolation of CA16 preceded the appearance of EV71. Based on the VP1 gene nucleotide sequences, 4 sub-genogroups of EV71 (C1, C2, B3 and B4) co-circulated and caused the outbreak of hand, foot and mouth disease in peninsular Malaysia in 1997. Two sub-genogroups (C1 and B4) were noted to cause the outbreak in 2000 in both peninsular Malaysia and Sarawak. EV71 of sub-genogroup B5 with smaller contribution from sub-genogroup C1 caused the outbreak in 2003. In the 2005 outbreak, besides the EV71 strains of sub-genogroup C1, EV71 strains belonging to sub-genogroup B5 were isolated but formed a cluster which was distinct from the EV71 strains from the sub-genogroup B5 isolated in 2003. The four EV71 strains isolated from clinical specimens of patients with hand, foot and mouth disease in the Sarawak outbreak in early 2006 also belonged to sub-genogroup B5. Phylogenetic analysis of the VP1 gene suggests that the EV71 strains causing the outbreak in Sarawak could have originated from peninsular Malaysia. Epidemiological and molecular data since 1997 show the recurrence of HFMD due to EV71 in Malaysia every 2 to 4 years. In each of the past outbreaks, more than one sub-genogroup of the virus co-circulate.
    Matched MeSH terms: Hand, Foot and Mouth Disease/epidemiology*; Hand, Foot and Mouth Disease/virology*
  2. Muhammad Anwar Hau A
    Med J Malaysia, 2008 Sep;63 Suppl C:75.
    PMID: 19230251
    Matched MeSH terms: Diabetic Foot/epidemiology*; Diabetic Foot/physiopathology
  3. Murty OP
    J Forensic Leg Med, 2007 May;14(4):225-7.
    PMID: 16914357
    This is a case report of an environmental accident due to lightning where one school boy sustained current, blast, and flame effects of it. A bolt of lightning directly struck the pole of a football ground and the scatter struck the child. In addition to burn injuries, he showed an exit wound of lightning in left foot. The exit wound of lightning current is a very rare finding. The body of victim had flame and heat effect of atmospheric electricity on head and neck, face, and trunk. In this incidence of lightning other team mates of the victim were safe. The patient survived the attack.
    Matched MeSH terms: Foot Injuries/etiology; Foot Injuries/pathology*
  4. Shimizu H, Utama A, Onnimala N, Li C, Li-Bi Z, Yu-Jie M, et al.
    Pediatr Int, 2004 Apr;46(2):231-5.
    PMID: 15056257
    Recently, there have been large outbreaks of hand, foot and mouth disease (HFMD) mainly caused by enterovirus 71 (EV71) associated with severe neurological diseases in the Western Pacific Region (WPR). To monitor the realtime trend of EV71 transmission throughout the WPR, the authors conducted a molecular epidemiological analysis of EV71 infection.
    Matched MeSH terms: Hand, Foot and Mouth Disease/epidemiology*; Hand, Foot and Mouth Disease/virology
  5. Zulkifli SS, Loh WP
    Foot Ankle Surg, 2020 Jan;26(1):25-32.
    PMID: 30600155 DOI: 10.1016/j.fas.2018.12.005
    The science of foot pressure studies the forces acting on the bottom and different regions of the foot along with the pressure exerted on the plantar surface with the interacting surface in contact. The information derived gave impact to human biomechanical assessment on body balance and ergonomics posture during gait. Various experiments designed at generating foot pressure data returns only with limited knowledge generated. Obviously, the procedure for experiment design needs to be properly understood from the foot morphology aspects; healthiness, footwear, surface in contact, load and forces impacts, and the foot sensitivity as well as the specification for the foot pressure. This paper reviews the proper preliminary experimental setups for foot pressure measurement analysis during static or dynamic gait. The strength and limitations of recent devices used and considerable variables are also discussed. The overall review explains that the comfortable natural gait in relation to the aspects of sensitivity, load, time duration, and stability are the standard considerations for plantar pressure experiments.
    Matched MeSH terms: Foot/anatomy & histology; Foot/physiology*
  6. Nurjasmine Aida Jamani, Noor Azimah Muhammad, Aida Jaffar, Saharuddin Ahmad, Noorlaili Tohit
    MyJurnal
    Foot problems are very common in diabetic patients but may go unnoticed by the patients and
    undiagnosed by the healthcare providers leading to substantial morbidity and amputations. The aims of this study were to assess patient’s foot care practices, awareness on their foot condition as well as to determine the prevalence of diabetic foot problem and its associated factors. Methods: This was a cross sectional study conducted among diabetic patients in a primary care clinic in Kuala Lumpur. Patients with diabetes, aged more than 18 years were selected using systematic random sampling technique. Patients were requested to answer a set of self-administered pre-tested questionnaire that obtain information on their socio-demographic profiles, diabetic clinical data, awareness on their feet condition and foot care practice. A trained clinician examined patients’ feet using a standard foot examination protocol. Results: A total of 166 patients with diabetes participated in this study. Nearly half of the patients (70, 42.2%) had diabetic foot problem but only 31 (18.7%) of them were aware of their foot condition. The three common problem were trophic changes of the skin (92.8%), followed with hair loss (71.1%) and callosity (65.7%). The independent associated factors for foot problem were increasing age (AOR=1.05, 95% CI 1.015-1.095; p
    Matched MeSH terms: Foot; Foot Diseases; Diabetic Foot
  7. Wang S, Xu W, Li LF
    Pediatr Infect Dis J, 2017 Sep;36(9):912-914.
    PMID: 28338526 DOI: 10.1097/INF.0000000000001593
    Cutaneous larva migrans is a frequent dermatologic problem among travelers in tropical areas, but its association with Löffler's syndrome is an extremely rare condition, particularly in children. Here, we describe a 6-year-old boy presenting cutaneous larva migrans associated with Löffler's syndrome.
    Matched MeSH terms: Foot/pathology; Foot/physiology
  8. Hussin P, Loke SC, Noor FM, Mawardi M, Singh VA
    Med J Malaysia, 2012 Aug;67(4):422-3.
    PMID: 23082455
    Melanomas on the foot are difficult to differentiate from diabetic foot ulcers (DFU). In particular, acral lentiginous and amelanotic melanomas have a high chance of being misdiagnosed. We present two patients with diabetes mellitus and malignant melanomas of the foot initially diagnosed as DFU. Both cases were treated with wide excision amputation and local dissection, without adjuvant chemotherapy or radiotherapy. Both patients remain disease-free up to the last follow-up visit. It is important to maintain a high index of suspicion and a skin biopsy should be done in any DFU with atypical features.
    Matched MeSH terms: Foot Diseases/complications; Foot Diseases/diagnosis*; Foot Diseases/surgery; Diabetic Foot/diagnosis*
  9. Ajit Singh V, Sandhu V, Tze Yong C, Yasin NF
    J Orthop Surg (Hong Kong), 2024;32(1):10225536241248706.
    PMID: 38662594 DOI: 10.1177/10225536241248706
    INTRODUCTION: The foot is a complex structure composed of several tissues, each of which can be the origin of the proliferation and development of the tumour. Most lesions about the foot are reactive or inflammatory, but some are true neoplasms.

    METHOD: This is a retrospective analysis of 4997 patient records treated in the Orthopaedic Oncology Unit of University Malaya Medical Centre, Malaysia, between 1 January 2010 to 31 December 2020. Demographic data of 195 patients with foot tumours were analysed out of 4997 neoplasm patients.

    RESULTS: There were 195 cases of foot tumours: 148 were benign, and 47 were malignant. 47 were bone tumours, 4 were metastases, and 144 were soft tissue tumours. Six patients succumbed to the disease, two cases of giant cell tumour (GCT) and one patient with synovial sarcoma had a recurrence. Treatment of foot tumours was wide resection in general. However, in metastasis cases, amputation was done. The majority of tumours were in the toes and dorsum of the foot. Soft tissue tumours of the foot occur in the elderly population in contrast to bone tumours, mainly in the second decade of life. The gender distribution was almost equal for foot tumours. Ganglion and Giant Cell Tumour of the bone are the commonest benign soft tissue and bone tumours. The most common malignant soft tissue and bone tumours are malignant melanoma and chondrosarcoma. The amputation rate is 5.64% the recurrence rate is 1.54%. Mortality rate is 3.08%. The MSTS score is 79%, and the TESS score is 76.23%.

    CONCLUSION: Foot tumours are relatively rare, mostly originating from soft tissue and exhibiting a benign nature. Nonetheless, a noteworthy proportion-approximately a quarter of these tumours-demonstrate malignancy. The surgical interventions undertaken in managing these tumours and associated functional outcomes generally yield acceptable results.

    Matched MeSH terms: Foot/surgery; Foot Diseases/pathology; Foot Diseases/surgery; Foot Diseases/therapy
  10. Lee SY, Park ME, Kim RH, Ko MK, Lee KN, Kim SM, et al.
    Vaccine, 2015 Jan 29;33(5):664-9.
    PMID: 25528521 DOI: 10.1016/j.vaccine.2014.12.007
    Of the seven known serotypes of foot-and-mouth disease virus (FMDV), type A has the most diverse variations. Genetic variations also occur frequently at VP1, VP2, VP3, and VP4 because these proteins constitute the viral capsid. The structural proteins of FMDV, which are closely related to immunologic correlations, are the most easily analyzed because they have highly accessible information. In this study we analyzed the type A vaccine viruses by alignment of available sequences in order to find appropriate vaccine strains. The matching rate of ASIA topotype-specific sites (20 amino acids) located on the viral surface, which are mainly VP1 and VP2, was highly related to immunologic reactivity. Among the available vaccines analyzed in this study, we suggest that A Malaysia 97 could be used as a vaccine virus as it has the highest genetic similarity and immunologic aspects to field strains originating in East Asia.
    Matched MeSH terms: Foot-and-Mouth Disease/immunology*; Foot-and-Mouth Disease/virology*; Foot-and-Mouth Disease Virus/classification; Foot-and-Mouth Disease Virus/genetics*; Foot-and-Mouth Disease Virus/immunology*; Foot-and-Mouth Disease Virus/isolation & purification
  11. Muhammad-Lutfi AR, Zaraihah MR, Anuar-Ramdhan IM
    Malays Orthop J, 2014 Nov;8(3):22-6.
    PMID: 26401231 MyJurnal DOI: 10.5704/MOJ.1411.005
    Good knowledge and practice regarding diabetic foot care will reduce the risk of diabetic foot complications and ultimately amputation. This study is conducted to assess patients' knowledge and compliance of diabetic foot care. A cross sectional study performed on patients who were admitted to HSNZ from the 1st September 2013 to 30th April 2014 for diabetic foot infections. They were interviewed with a questionnaire of 15 'yes' or 'no' questions on foot care knowledge and practice. Score of 1 was given for each 'yes' answer. The level of knowledge and practice, whether good or poor, was determined based on the median score of each category. The result was tested using a chi-square test in SPSS version 17. A total of 157 patients were included in this study with a mean age of 56.33 years (31-77). There were 72 male (45.9%) and 85 female (54.1%) patients with the majority of them being Malays (154 patients, 98.1%). Majority of the patients (58%) had poor foot care knowledge while 97 patients (61.8%) had poor diabetic foot care practice as compared to the median score. Based on the chi square test of relatedness, there was no significant association between knowledge and practice with any of the variables. In conclusion, the majority of patients admitted for diabetic foot infections had poor knowledge and practice of diabetic foot care. Education regarding foot care strategies should be emphasized and empowered within the diabetic population.
    Study site: Hospital Sultanah Nur Zahirah, Kuala Terengganu,Terengganu, Malaysia
    Matched MeSH terms: Diabetic Foot*
  12. Ahmad Sharoni SK, Minhat HS, Mohd Zulkefli NA, Baharom A
    Int J Older People Nurs, 2016 Sep;11(3):214-39.
    PMID: 26916809 DOI: 10.1111/opn.12112
    AIMS AND OBJECTIVES: To assess the effectiveness of health education programmes to improve foot self-care practices and foot problems among older people with diabetes.

    BACKGROUND: The complications of diabetes among older people are a major health concern. Foot problems such as neuropathy, ulcer and ultimately amputation are a great burden on older people with diabetes. Diabetes foot education programmes can influence the behaviour of older people in practising foot self-care and controlling the foot problems. However, the educational approaches used by the educators are different. Therefore, it is important to assess the education programmes from various evidence-based practices.

    DESIGN: Six databases, EBSCOhost medical collections (MEDLINE, CINAHL, Psychology and Behavioral Sciences Collection), SAGE, Wiley Online Library, ScienceDirect, SpringerLink and Web of Science, were used to search for articles published from January 2000 to March 2015. The search was based on the inclusion criteria and keywords including 'foot', 'care' and 'diabetes'. Fourteen studies were assessed and reviewed in the final stage.

    CONCLUSIONS: Health education programmes varied according to their design, setting, approach, outcome measured and results. Foot assessment, verbal and written instructions and discussion were proved to improve the foot self-care and foot problems. Subsequent follow-ups and evaluations had a significant effect. An improvement was observed in foot self-care scores and foot problems (such as neuropathy, foot disability, lesion, ulcer, tinea pedis and callus grade) after implementation of the health education programme.

    IMPLICATIONS FOR PRACTICE: The findings of this study support the claim that a health education programme increases the foot self-care scores and reduces the foot problems. However, there were certain methodological concerns in the reviewed articles, indicating the need for further evaluation. In future, researchers and practitioners must implement a vigorous education programme focusing on diabetes foot self-care among the older population.

    Matched MeSH terms: Diabetic Foot/prevention & control*
  13. Yeap JS, Anbanandan S, Yeap JK, Borhan Tan M, Harwant S
    Med J Malaysia, 2001 Mar;56(1):102-3.
    PMID: 11503287
    Matched MeSH terms: Diabetic Foot/complications*
  14. Abdul Yamin NAA, Basaruddin KS, Salleh AF, Salim MS, Wan Muhamad WZA
    Appl Bionics Biomech, 2021;2021:8842591.
    PMID: 33603827 DOI: 10.1155/2021/8842591
    Objective: The aim of this study was to investigate the effects of surface stiffness on multisegment foot kinematics and temporal parameters during running.

    Methods: Eighteen male subjects ran on three different surfaces (i.e., concrete, artificial grass, and rubber) in both heeled running shoes (HS) and minimal running shoes (MS). Both these shoes had dissimilar sole profiles. The heeled shoes had a higher sole at the heel, a thick base, and arch support, whereas the minimal shoes had a flat base sole. Indeed, the studied biomechanical parameters responded differently in the different footwear during running. Subjects ran in recreational mode speed while 3D foot kinematics (i.e., joint rotation and peak medial longitudinal arch (MLA) angle) were determined using a motion capture system (Qualysis, Gothenburg, Sweden). Information on stance time and plantar fascia strain (PFS) was also collected.

    Results: Running on different surface stiffness was found to significantly affect the peak MLA angles and stance times for both HS and MS conditions. However, the results showed that the joint rotation angles were not sensitive to surface stiffness. Also, PFS showed no relationship with surface stiffness, as the results were varied as the surface stiffness was changed.

    Conclusion: The surface stiffness significantly contributed towards the effects of peak MLA angle and stance time. These findings may enhance the understanding of biomechanical responses on various running surfaces stiffness in different shoe conditions.

    Matched MeSH terms: Foot; Foot Orthoses
  15. Neoh SL
    Complement Ther Med, 2018 Dec;41:161-168.
    PMID: 30477833 DOI: 10.1016/j.ctim.2018.09.017
    This paper explores the electrical nature of sandy beach and proposes a pathway for the therapeutic effects of beach going. The electric potential and current generated on the ground across the human body and resistors were measured. The ground was found to have a non-homogenous electric potential which generated a potential difference between any two points on the ground. A power curve, similar to a battery, in the nanowatt range was obtained. This power appeared to be stable across time but varies across ground location. Standing on the beach with dry feet did not allow any current in the micro-ampere range to conduct. But upon moistening the feet, the body electrical resistance was reduced by 94% and the ground potential difference across the two feet was sufficient to drive a micro-ampere range current through the body. This may be one reason for the therapeutic effects of being on the beach.
    Matched MeSH terms: Foot/physiology*
  16. Vaishya R, Vijay V, Ghogare P, Vaish A
    Malays Orthop J, 2015 Mar;9(1):35-37.
    PMID: 28435595 DOI: 10.5704/MOJ.1503.005
    The presence of lytic lesions in the bones of foot raises a number of diagnostic possibilities ranging from infection, inflammatory pathology to neoplastic conditions. Although the radiological picture is not pathognomonic of any pathology, clinical history and histopathological examination can help to clinch the diagnosis. We present a case of multiple lytic lesions of the foot and discuss possible differential diagnoses. The patient was diagnosed as a case of madura foot and the lesions responded to surgical debridement and anti-fungal treatment with a good functional outcome. Madura foot is an uncommon, chronic granulomatous fungal or bacterial infection with a predilection in people who walk barefoot. Although known for a specific geographical distribution, madura foot should be kept as a possible diagnosis in patients presenting with lytic lesions of the foot due to population emigration across the world.
    Matched MeSH terms: Foot; Foot Bones
  17. Kirimtat A, Krejcar O, Selamat A, Herrera-Viedma E
    BMC Bioinformatics, 2020 Mar 11;21(Suppl 2):88.
    PMID: 32164529 DOI: 10.1186/s12859-020-3355-7
    BACKGROUND: In biomedicine, infrared thermography is the most promising technique among other conventional methods for revealing the differences in skin temperature, resulting from the irregular temperature dispersion, which is the significant signaling of diseases and disorders in human body. Given the process of detecting emitted thermal radiation of human body temperature by infrared imaging, we, in this study, present the current utility of thermal camera models namely FLIR and SEEK in biomedical applications as an extension of our previous article.

    RESULTS: The most significant result is the differences between image qualities of the thermograms captured by thermal camera models. In other words, the image quality of the thermal images in FLIR One is higher than SEEK Compact PRO. However, the thermal images of FLIR One are noisier than SEEK Compact PRO since the thermal resolution of FLIR One is 160 × 120 while it is 320 × 240 in SEEK Compact PRO.

    CONCLUSION: Detecting and revealing the inhomogeneous temperature distribution on the injured toe of the subject, we, in this paper, analyzed the imaging results of two different smartphone-based thermal camera models by making comparison among various thermograms. Utilizing the feasibility of the proposed method for faster and comparative diagnosis in biomedical problems is the main contribution of this study.

    Matched MeSH terms: Foot/physiology
  18. Aboutorabi A, Saeedi H, Kamali M, Farahmand B, Eshraghi A, Dolagh RS
    Prosthet Orthot Int, 2014 Jun;38(3):218-23.
    PMID: 23986466 DOI: 10.1177/0309364613496111
    BACKGROUND: Flat foot in children is a common deformity in which the medial longitudinal arch is reduced or eliminated.
    OBJECTIVES: The objective of this article was to compare flat foot and healthy children on the displacement of the center of pressure and walking parameters in children with two common orthoses (functional foot orthosis and medical shoe).
    STUDY DESIGN: Comparative study.
    METHODS: This study included 30 children with flat foot and 20 healthy children as a control group. The step length and width, walking velocity, symmetry, and center of pressure (CoP) displacements were recorded and compared for three conditions: functional foot orthosis and regular shoe, a medical shoe and barefoot.
    RESULTS: The results from the CoP displacements showed that the regular shoe with functional foot orthosis caused a significant decrease in the level of displacement of the CoP in flat foot children. The findings indicated a significant improvement in symmetry of steps and walking speed with the functional foot orthosis in comparison to the medical shoe in flat foot children.
    CONCLUSION: The CoP displacement was decreased and the percentage of gait symmetry and walking speed were increased by the use of regular shoes with a functional foot orthosis in comparison to the medical shoes.
    CLINICAL RELEVANCE: An orthopaedic shoe can be expensive, and in particular heavy with most children reluctant to wear it. This study focussed on the CoP displacement and selected gait parameters with an orthopaedic shoe and functional foot orthosis, and showed that a combined prescription of a functional foot orthosis and with regular shoes may be a useful alternative for children with moderate flat foot.
    KEYWORDS: Center of pressure; flexible flat foot; functional foot orthosis; gait; medical shoe
    Matched MeSH terms: Flatfoot/physiopathology*; Flatfoot/therapy*; Foot/physiopathology*; Foot Orthoses*
  19. Fauzi AA, Yang CT
    Aust Fam Physician, 2013 Jan-Feb;42(1-2):55-6.
    PMID: 23529463
    Charcot neuro-osteoarthropathy (CNO) of the foot is a devastating neuropathic complication of diabetes. It is characterised by deformity of the foot architecture,which can be initiated by trauma to the neuropathic limb or occur spontaneously.The acute phase of the disease is often misdiagnosed and can rapidly lead to deformity and amputation. The aim of management is to halt further bone destruction through immobilisation of the affected limb.
    Matched MeSH terms: Diabetic Foot/diagnosis; Diabetic Foot/etiology; Diabetic Foot/therapy*
  20. Abu J, Wünschmann A, Redig PT, Feeney D
    J. Avian Med. Surg., 2009 Mar;23(1):44-8.
    PMID: 19530406
    A 32-year-old female American flamingo (Phoenicopterus ruber) was presented with a squamous cell carcinoma of the middle digit of the right foot. No clinical, hematologic, or radiologic evidence of metastasis was present. Salvage amputation of the digit resulted in complete cure, whereas previous electrosurgery and radiation therapy were unsuccessful. Three years later, another squamous cell carcinoma was diagnosed in the middle digit of the left foot. The digit was also amputated. Seven months after the second amputation, the bird did not have any recurrence or signs of metastasis.
    Matched MeSH terms: Foot Diseases/pathology; Foot Diseases/surgery; Foot Diseases/veterinary*
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