MyMedR

Unicystic Ameloblastoma: A Perception for the Cautious Interpretation of Radiographic and Histological Findings

Arora S

J Coll Physicians Surg Pak, 2015 Oct;25(10):761764-764.

PMID: 26454399 DOI: 10.2015/JCPSP.761764

The term Unicystic Ameloblastoma (UA) refers to those cystic lesions that show clinical and radiological characteristics of an odontogenic cyst but on histological examination show a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. Till date, lot of controversies exist among oral surgeons and oral pathologists regarding this entity. An attempt is being made here to discuss all the diagnostic dilemmas associated with UA.

Matched MeSH terms: Odontogenic Cysts/diagnosis; Odontogenic Cysts/pathology; Odontogenic Cysts/radiography

Fulltext Gastric duplication cyst with a red flag presentation: a case report

Alagoo D, Sellappan H, Jayasilan J, Azizan N, Hayati F

Pan Afr Med J, 2021;39:141.

PMID: 34527157 DOI: 10.11604/pamj.2021.39.141.29895

Gastric duplication cyst (GDC) is a rare congenital malformation of the gastrointestinal (GI) tract. Despite being benign in the entity, its complications vary from an asymptomatic abdominal mass to fulminant or massive GI bleeding. A 28-year-old lady presented with unexplained GI haemorrhage, in which the upper endoscopy showed a classic feature of GI stromal tumour. The preoperative diagnosis was also confirmed by the computed tomography. She subsequently underwent surgical resection and the final histopathology was consistent with a benign entity of GDC.

Matched MeSH terms: Cysts/congenital; Cysts/diagnosis*; Cysts/surgery

Fulltext Hepatic Adenomatosis: Diagnosis and Management Dilemma

Norly, S., Razman, J.

International Medical Journal Malaysia, 2010;9(2):59-61.

MyJurnal

Hepatic adenomatosis is a rare, benign tumour of the liver. It was ﬁrst described by Flejou et al as multiple adenomas in an otherwise normal liver parenchyma. Although benign, it can present as a diagnostic
challenge because the lesions can be difﬁ cult to distinguish from other hepatic tumours. Patients can be
asymptomatic and the diagnosis may only be made incidentally. We describe the case of 40-year-old Malay lady who was incidentally found to have hepatomegaly. Radiological examinations revealed a complex left ovarian cyst with multiple liver lesions. Biopsy of the liver lesion showed features of hepatic adenomatosis. Literature review was done and the dilemma in managing her was discussed.

Matched MeSH terms: Ovarian Cysts

Fulltext Intracystic haemorrhage in a non-endometriotic mullerian vaginal cyst: an unexpected phenomenon

Ng, Beng Kwang, Lim, PS, Shafiee MN, Abdul Kadir AK, Nordashima AS, Omar MH

Journal of Surgical Academia, 2016;6(1):35-38.

MyJurnal

We report a case of rare, Mullerian vaginal cyst with intracystic haemorrhage in the absence of endometrial components. To date, this is the second case reported in the literature. A 51-year-old post-menopausal woman with history of anterior vaginal wall cyst was misdiagnosed to have cystocele. The cyst was excised and the content was old blood mixed with mucous. Histopathological examination revealed a Mullerian vaginal cyst without endometrial component. Thus, diagnosis and management of vaginal cyst was revisited and discussed.

Matched MeSH terms: Cysts

Fulltext Tornwaldt Cyst: a case report of unusual dental symptoms

Asfizahrasby Mohd Rasoul, Norliwati Ibrahim

International Medical Journal Malaysia, 2017;16(21):25-25.

MyJurnal

Tornwaldt's (Thornwaldt's) or nasopharyngeal cyst is an uncommon developmental
benign cyst located in the midline postero-superior wall of nasopharynx. Incidence reported in
general population is 0.06%. It occurred in the potential space due to outpouching of ectoderm into
the pharyngobasilar fascia at the site where notochord attached to pharyngeal ectoderm. (Copied from article).

Matched MeSH terms: Cysts

Fulltext Recurrent haemorrhagic ovarian cyst and anticoagulant therapy: a case report with review of treatment modalities

Nagandla K, Jamli MFBM, Hanim F, Xu Mei JL, Din SFS

Pan Afr Med J, 2021;40:52.

PMID: 34795832 DOI: 10.11604/pamj.2021.40.52.30961

The common gynaecological causes of acute pelvic pain include ruptured ectopic pregnancy, haemorrhagic corpus luteal cyst or torsion of an ovarian cyst. Ovarian vascular accidents are reported in women on oral anticoagulation presenting as an acute pelvic pain. Although such vascular accidents with anticoagulation therapy are an unusual entity, a meticulous history, clinical examination, and laboratory workup to confirm the diagnosis and timely intervention is needed to reduce attending morbidity and mortality. However, a standard algorithm for management is not described in the literature. We hereby report successful management of recurrent hemorrhagic ovarian cyst due to coagulopathy in a woman with mechanical heart valves with timely surgical intervention. This case report discusses operative versus non operative management approach and may provide value addition to readers encountering such cases in their clinical practice.

Matched MeSH terms: Ovarian Cysts/diagnosis*; Ovarian Cysts/etiology; Ovarian Cysts/therapy

Fulltext Subspace-based technique for speckle noise reduction in ultrasound images

Yahya N, Kamel NS, Malik AS

Biomed Eng Online, 2014;13(1):154.

PMID: 25421914 DOI: 10.1186/1475-925X-13-154

Ultrasound imaging is a very essential technique in medical diagnosis due to its being safe, economical and non-invasive nature. Despite its popularity, the US images, however, are corrupted with speckle noise, which reduces US images qualities, hampering image interpretation and processing stage. Hence, there are many efforts made by researches to formulate various despeckling methods for speckle reduction in US images.

Matched MeSH terms: Cysts/ultrasonography

Compression neuropathy of the common peroneal nerve secondary to a ganglion cyst

Yazid Bajuri M, Tan BC, Das S, Hassan S, Subanesh S

Clin Ter, 2011;162(6):549-52.

PMID: 22262327

There are various causes of the common peroneal nerve palsy. However, common peroneal nerve palsy caused by ganglia are uncommon. We hereby present a case of a 55-year-old man with a 1 week history of foot drop and swelling in the region of the right leg. Physical examination and nerve conduction study studies confirmed a diagnosis of common peroneal nerve palsy. Magnetic resonance imaging (MRI) revealed a lobulated, elongated cystic-appearing mass anterior to the head of fibula. Surgical decompression of the nerve with removal of the mass was performed. Surgical pathology reports confirmed the diagnosis of a ganglion cyst. Findings on physical examination, nerve conduction study and MRI results of this interesting case are being discussed. We wish to highlight that even a tumour which is benign and within the nerve sheath can cause compression.

Matched MeSH terms: Ganglion Cysts/complications*

Primary infertility in a phenotypic male with 46XX chromosomal constitution

Tan TT, Khalid BA

Postgrad Med J, 1993 Apr;69(810):315-7.

PMID: 8321801

The case of a 32 year old male with normal male adrenarchal hair pattern, bilateral gynaecomastia, a small phallus, hypospadias and bilateral poorly developed testes presenting with primary infertility secondary to azoospermia and a pelvic cyst is described. Repeated chromosomal analysis showed 46XX chromosomal constitution. Laparotomy revealed a simple cyst between the urinary bladder and the rectum. XX male syndrome is a rare cause of male infertility. The majority of cases is due to interchange of a fragment of the short arm of the Y chromosome containing the region that encodes the testes determining factor with the X chromosome. The presence of a simple cyst in the anatomical location of the uterus to our knowledge has not been reported in the literature.

Matched MeSH terms: Cysts/etiology

A unilateral mesenchymal disorder of the head

Raman R, Kumar V, Arianayagam S, Peh SC

J Craniomaxillofac Surg, 1989 Apr;17(3):143-5.

PMID: 2708537

A hitherto undescribed group of lesions consisting of cystic bony lesions, exostosis, fibromatous lesion, unilateral tonsillar hypertrophy, epidermoid cyst (cholesteatoma) and hyperplasia of the mandible confined to the left side of the face is reported. The case may represent a variant of the Proteus syndrome.

Matched MeSH terms: Bone Cysts*

Orthokeratinised odontogenic keratocysts in Malaysians

Siar CH, Ng KH

Br J Oral Maxillofac Surg, 1988 Jun;26(3):215-20.

PMID: 2456095

The records of the Division of Stomatology, Institute for Medical Research, Kuala Lumpur, Malaysia, were reviewed for the incidence of odontogenic keratocysts of the orthokeratinised variety, during the 20-year-period, 1967 to 1986. Nine cases were found. The clinical, histological and radiological features of these cases are reported. Many features were similar to previous reports of this entity but a peak incidence in the second decade of life, an almost even distribution in the maxilla and mandible, and a distinct predilection for the Chinese were observed. It is suggested that these features may be peculiar to Malaysians.

Matched MeSH terms: Odontogenic Cysts/pathology*

Odontogenic keratocyst: a study of 53 cases in Malaysia

Siar CH, Ng KH, Murugasu P

Ann Dent, 1986;45(2):15-8.

PMID: 3468871

Matched MeSH terms: Odontogenic Cysts/ethnology*

Fulltext Large type I choledochal cyst in adults: a case report

Krishnan MMS, Couper NTA

Med J Malaysia, 1984 Jun;39(2):163-6.

PMID: 6392840

Matched MeSH terms: Cysts/diagnosis*

Mullerian duct cyst (utricular cyst): treatment with the transvesical, transtrigonal approach

Goon HK, Tan KC, Sakijan AS

Aust N Z J Surg, 1987 Sep;57(9):683-6.

PMID: 3689258

The diagnosis of mullerian duct or utricular cyst should be considered in a child with urinary difficulties and a palpable midline, anterior rectal mass. Endoscopic cannulation of the cyst has been found to be the most useful diagnostic test. Infection should be treated with the appropriate antibiotics before definitive treatment. Surgical excision offers the best result. The transperitoneal and posterior parasacral approaches have been described but we favour the transvesical, transtrigonal approach which we find highly satisfactory. The risk of malignancy at a later age is an added indication for surgery.

Matched MeSH terms: Cysts/surgery*

Fulltext Ultrasound in the diagnosis of palpable abdominal masses in children

Annuar Z, Sakijan AS, Annuar N, Kooi GH

Med J Malaysia, 1990 Dec;45(4):281-7.

PMID: 2152047

Ultrasound examinations were done to evaluate clinically palpable abdominal masses in 125 children. The examinations were normal in 21 patients. In 15 patients, the clinically palpable masses were actually anterior abdominal wall abscesses or hematomas. Final diagnosis was available in 87 of 89 patients with intraabdominal masses detected on ultrasound. The majority (71%) were retroperitoneal masses where two-thirds were of renal origin. Ultrasound diagnosis was correct in 68 patients (78%). All cases of hydronephrosis were correctly diagnosed based on characteristic ultrasound appearances. Correct diagnoses of all cases of adrenal hematoma, psoas abscess, liver hematoma, liver abscess and one case of liver metastases were achieved with correlation of relevant clinical information.

Matched MeSH terms: Cysts/ultrasonography

The superior efficacy of chloroquine over buparvaquone in reducing the chronic cerebral Toxoplasma gondii cysts load and improving the ultrastructural pathology in an immunocompromised murine model

Fahmy MEA, Abdel-Aal AA, Hassan SI, Shalaby MA, Esmat M, Abdel Shafi IR, et al.

Trop Biomed, 2023 Mar 01;40(1):115-123.

PMID: 37356011 DOI: 10.47665/tb.40.1.018

Toxoplasma gondii, the etiologic agent of toxoplasmosis, infects about 30 - 50% of the world population. The currently available anti-Toxoplasma agents have serious limitations. The present study aimed to investigate the effects of two antimalarials; buparvaquone (BPQ) and chloroquine (CQ), on immunocompromised mice with chronic cerebral toxoplasmosis, using spiramycin as a reference drug. The assessed parameters included the estimation of mortality rates (MR) among mice of the different study groups, in addition to the examination of the ultrastructural changes in the brain tissues by transmission electron microscopy. The results showed that only CQ treatment could decrease the MR significantly with zero deaths, while both spiramycin and BPQ caused an insignificant reduction of MR compared to the infected non-treated group. All the used drugs decreased the number of mature ruptured cysts significantly compared to the infected non-treated group, while only CQ increased the number of atrophic and necrotic cysts significantly. Furthermore, both spiramycin and BPQ improved the microvasculopathy and neurodegeneration accompanying the infection with different degrees of reactive astrocytosis and neuronal damage with the best results regarding the repair of the microvascular damage with less active glial cells, and normal neurons in the CQ-treated group. In conclusion, this study sheds light on CQ and its excellent impact on treating chronic cerebral toxoplasmosis in an immunocompromised mouse model.

Matched MeSH terms: Cysts*

Fulltext Homeobox Genes in Odontogenic Lesions: A Scoping Review

Hii EPW, Ramanathan A, Pandarathodiyil AK, Wong GR, Sekhar EVS, Binti Talib R, et al.

Head Neck Pathol, 2023 Mar;17(1):218-232.

PMID: 36344906 DOI: 10.1007/s12105-022-01481-2

BACKGROUND: Homeobox genes play crucial roles in tooth morphogenesis and development and thus mutations in homeobox genes cause developmental disorders such as odontogenic lesions. The aim of this scoping review is to identify and compile available data from the literatures on the topic of homeobox gene expression in odontogenic lesions.

METHOD: An electronic search to collate all the information on studies on homeobox gene expression in odontogenic lesions was carried out in four databases (PubMed, EBSCO host, Web of Science and Cochrane Library) with selected keywords. All papers which reported expression of homeobox genes in odontogenic lesions were considered.

RESULTS: A total of eleven (11) papers describing expression of homeobox genes in odontogenic lesions were identified. Methods of studies included next generation sequencing, microarray analysis, RT-PCR, Western blotting, in situ hybridization, and immunohistochemistry. The homeobox reported in odontogenic lesions includes LHX8 and DLX3 in odontoma; PITX2, MSX1, MSX2, DLX, DLX2, DLX3, DLX4, DLX5, DLX6, ISL1, OCT4 and HOX C in ameloblastoma; OCT4 in adenomatoid odontogenic tumour; PITX2 and MSX2 in primordial odontogenic tumour; PAX9 and BARX1 in odontogenic keratocyst; PITX2, ZEB1 and MEIS2 in ameloblastic carcinoma while there is absence of DLX2, DLX3 and MSX2 in clear cell odontogenic carcinoma.

CONCLUSIONS: This paper summarized and reviews the possible link between homeobox gene expression in odontogenic lesions. Based on the current available data, there are insufficient evidence to support any definite role of homeobox gene in odontogenic lesions.

Matched MeSH terms: Odontogenic Cysts*

Lactase can target cellular differentiation of Acanthamoeba castellanii belonging to the T4 genotype

Simau FA, Ahmed U, Khan KM, Khan NA, Siddiqui R, Alharbi AM, et al.

Parasitol Res, 2024 Jan 31;123(2):117.

PMID: 38294565 DOI: 10.1007/s00436-024-08131-2

The free living Acanthamoeba spp. are ubiquitous amoebae associated with potentially blinding disease known as Acanthamoeba keratitis (AK) and a fatal central nervous system infection granulomatous amoebic encephalitis (GAE). With the inherent ability of cellular differentiation, it can phenotypically transform to a dormant cyst form from an active trophozoite form. Acanthamoeba cysts are highly resistant to therapeutic agents as well as contact lens cleaning solutions. One way to tackle drug resistance against Acanthamoeba is by inhibiting the formation of cysts from trophozoites. The biochemical analysis showed that the major component of Acanthamoeba cyst wall is composed of carbohydrate moieties such as galactose and glucose. The disaccharide of galactose and glucose is lactose. In this study, we analyzed the potential of lactase enzyme to target carbohydrate moieties of cyst walls. Amoebicidal assessment showed that lactase was ineffective against trophozoite of A. castellanii but enhanced amoebicidal effects of chlorhexidine. The lactase enzyme did not show any toxicity against normal human keratinocyte cells (HaCaT) at the tested range. Hence, lactase can be used for further assessment for development of potential therapeutic agents in the management of Acanthamoeba infection as well as formulation of effective contact lens disinfectants.

Matched MeSH terms: Cysts*

Fulltext Pelvic aneurysmal bone cyst

Sharifah M, Nurhazla H, Suraya A, Tan S

Biomed Imaging Interv J, 2011 Oct;7(4):e24.

PMID: 22279501 MyJurnal DOI: 10.2349/biij.7.4.24

This paper describes an extremely rare case of a huge aneurysmal bone cyst (ABC) in the pelvis, occurring in the patient's 5(th) decade of life. The patient presented with a history of painless huge pelvic mass for 10 years. Plain radiograph and computed tomography showed huge expansile lytic lesion arising from the right iliac bone. A biopsy was performed and histology confirmed diagnosis of aneurysmal bone cyst. Unfortunately, the patient succumbed to profuse bleeding from the tumour.

Matched MeSH terms: Bone Cysts, Aneurysmal

Fulltext Tarsal tunnel syndrome caused by ganglion

Ng WM, Chan KY

Med J Malaysia, 2004 Dec;59 Suppl F:69-71.

PMID: 15941169

We report a case of delayed diagnosis of tarsal tunnel syndrome caused by a ganglion arising from the talo-calcaneal joint. Unusually the symptoms were mainly due to the lateral planter nerve compression with a positive Tinel's sign. A surgical decompression was successful in relieving the dysaesthesia in spite of a 7 years history.

Matched MeSH terms: Ganglion Cysts/complications*; Ganglion Cysts/diagnosis; Ganglion Cysts/surgery

Displaying publications 21 - 40 of 166 in total