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Fulltext Determinants of 3Rs behaviour in plastic usage: A study among Malaysians

Chun T'ing L, Moorthy K, Yoon Mei C, Pik Yin F, Zhi Ying W, Wei Khong C, et al.

Heliyon, 2020 Dec;6(12):e05805.
PMID: 33409389 DOI: 10.1016/j.heliyon.2020.e05805

This research was conducted to explore the factors affecting Malaysians' application of reduce, reuse and recycle (3Rs) concept in plastic usage. This study adopted variables from the Theory of Planned Behaviour (TPB), namely, attitude, subjective norm and perceived behavioural control and added on two more variables, habit and facilitating conditions to study the plastic usage. Self-administered questionnaires were used to collect the data and analysis done. The results showed that all variables influence the plastic usage behaviour. This research contributes to a better understanding of the relationship between the determinants of behavioural intention of 3Rs application on plastic usage. Through the suggestions of suitable strategies, this research would contribute to reducing environment pollution caused by plastic waste.
Fulltext Does military spending stifle economic growth? The empirical evidence from non-OECD countries

Azam M

Heliyon, 2020 Dec;6(12):e05853.
PMID: 33426342 DOI: 10.1016/j.heliyon.2020.e05853

Undeniably, peace and long-term sustainable economic development are the prime agenda of all countries. This study aims to empirically evaluate the impact of military spending on economic growth for a panel of 35 non-OECD countries over 1988-2019. A multivariate regression model based on the augmented production function is used to achieve the objective of the study. The panel autoregressive distributed lag (ARDL)/pooled mean group (PMG) technique is employed, while, in addition the robust least squares and fixed-effect estimators are implemented for the robustness of the results. This study found a clear negative effect of military spending on economic growth. The pairwise Dumitrescu Hurlin panel causality test results exhibit bi-directional causality between military expenses and economic growth. Overall, these estimates provide strong support that military expenditure is not beneficial rather detrimental to economic growth. The empirical findings of this study suggest that policymakers need to redesign the military budget to stimulate economic growth and improve social welfare.
Fulltext Factors affecting risk tolerance among small-scale seasonal commodity farmers and strategies for its improvement

Agussabti A, Romano R, Rahmaddiansyah R, Isa RM

Heliyon, 2020 Dec;6(12):e05847.
PMID: 33426340 DOI: 10.1016/j.heliyon.2020.e05847

In developing countries, farming businesses are dominated by small-scale farmers with limited resources. Such farmers are subjected to high risks, influencing the success rate of their agricultural endeavors. This study, conducted in Aceh Province, Indonesia, measured the risk tolerance among six groups of farmers with businesses based on the following seasonal commodities: paddy, corn, soy, chili, potato, and tomato. A total of 360 respondents were surveyed and 54 key respondents interviewed. A Likert scale was used to assess the risk tolerance levels of the farmers, and ordinal regression analysis to analyze the factors influencing risk tolerance. Paddy, chili, and potato farmers had a relatively high tolerance to farming risks, whereas corn and tomato farmers showed a moderate tolerance. Soy farmers were classified into the low risk tolerance category. Ordinal analysis indicated that the risk tolerance of farmers in each commodity group was influenced by specific factors. Overall, it was found that the farmers' attitudes to risk tolerance were significantly affected by the following factors: experience, education, farming income, capital, land status, and land size. An intervention strategy including improvements in the curriculum, actors, network, scope of clusters, and technology are among the strategies required to positively improve farmers' perceptions and increase their tolerance to farming risks.
Fulltext Problem characterization for visual analytics in MOOC learner's support monitoring: A case of Malaysian MOOC

Asli MF, Hamzah M, Ibrahim AAA, Ayub E

Heliyon, 2020 Dec;6(12):e05733.
PMID: 33426320 DOI: 10.1016/j.heliyon.2020.e05733

Malaysia and many other developing countries progressively adopting massively open online course (MOOC) in their national higher education approach. We have observed an increasing need for facilitating MOOC monitoring that is associated with the rising adoption of MOOCs. Our observation suggests that recent adoption cases led analyst and instructors to focus on monitoring enrolment and learning activities. Visual analytics in MOOC support education analysts in analyzing MOOC data via interactive visualization. Existing literature on MOOC visualization focuses on enabling visual analysis on MOOC data from forum and course material. We found limited studies that investigate and characterize domain problems or design requirements of visual analytics for MOOC. This paper aims to present the empirical problem characterization and abstraction for visual analytics in MOOC learner's support monitoring. Detailed characterization and abstraction of the domain problem help visualization designer to derive design requirements in generating appropriate visualization solution. We examined the literature and conducted a case study to elicit a problem abstraction based on data, users, and tasks. We interviewed five Malaysian MOOC experts from three higher education institutes using semi-structured questions. Our case study reveals the priority of enabling MOOC analysis on learner's progression and course completion. There is an association between design and analysis priority with the pedagogical type of implemented MOOC and users. The characterized domain problems and requirements offer a design foundation for visual analytics in MOOC monitoring analysis.
Fulltext Acute oral toxicity of the ellagitannin geraniin and a geraniin-enriched extract from Nephelium lappaceum L rind in Sprague Dawley rats

Moorthy M, Khoo JJ, Palanisamy UD

Heliyon, 2019 Aug;5(8):e02333.
PMID: 31508523 DOI: 10.1016/j.heliyon.2019.e02333

Despite the lack of its toxicity evaluation, traditional herbal products are being widely used for various health indications. Geraniin, an ellagitannin, is a bioactive compound found in many traditional herbal medicines. In spite its numerous health benefits ranging from anti-inflammatory, anti-hyperglycaemic, hepatoprotective, anti-cancer and anti-microbial, no toxicity data on geraniin is available. The objective of this study is to evaluate the acute oral toxicity of geraniin and an enriched geraniin-extract of Nephelium lappaceum L rind. This study followed the guidelines of the OECD 423 acute oral toxicity test. Subsequent to a single oral administration of the test compounds, the rats were observed for 14 days for signs of toxicity and mortality. Following euthanasia, full blood count, biochemistry of blood and histopathology assessment of organs were carried out. All parameters analysed indicated insignificant difference compared to control. The LD50 cut-off values for both geraniin and geraniin-enriched extract was established to be 2000 mg/kg b. w., following a single oral dose. It was however observed that the hepatocytes of three geraniin-administered rats exhibited a 'foamy appearance'. As such, the no-observed-adverse-effect level of geraniin is below 2000 mg/kg, while that of geraniin-enriched extract is up to 2000 mg/kg. Further detailed toxicity studies are required to establish geraniin or its enriched extract from Nephelium lappaceum L rind safe for human consumption.
Fulltext Predicting the degradation potential of Acid blue 113 by different oxidants using quantum chemical analysis

Asghar A, Bello MM, Raman AAA, Daud WMAW, Ramalingam A, Zain SBM

Heliyon, 2019 Sep;5(9):e02396.
PMID: 31517121 DOI: 10.1016/j.heliyon.2019.e02396

In this work, quantum chemical analysis was used to predict the degradation potential of a recalcitrant dye, Acid blue 113, by hydrogen peroxide, ozone, hydroxyl radical and sulfate radical. Geometry optimization and frequency calculations were performed at 'Hartree Fock', 'Becke, 3-parameter, Lee-Yang-Parr' and 'Modified Perdew-Wang exchange combined with PW91 correlation' levels of study using 6-31G* and 6-31G** basis sets. The Fourier Transform-Raman spectra of Acid blue 113 were recorded and a complete analysis on vibrational assignment and fundamental modes of model compound was performed. Natural bond orbital analysis revealed that Acid blue 113 has a highly stable structure due to strong intermolecular and intra-molecular interactions. Mulliken charge distribution and molecular electrostatic potential map of the dye also showed a strong influence of functional groups on the neighboring atoms. Subsequently, the reactivity of the dye towards the oxidants was compared based on the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy values. The results showed that Acid blue 113 with a HOMO value -5.227 eV exhibits a nucleophilic characteristic, with a high propensity to be degraded by ozone and hydroxyl radical due to their lower HOMO-LUMO energy gaps of 4.99 and 4.22 eV respectively. On the other hand, sulfate radical and hydrogen peroxide exhibit higher HOMO-LUMO energy gaps of 7.92 eV and 8.10 eV respectively, indicating their lower reactivity towards Acid blue 113. We conclude that oxidation processes based on hydroxyl radical and ozone would offer a more viable option for the degradation of Acid blue 113. This study shows that quantum chemical analysis can assist in selecting appropriate advanced oxidation processes for the treatment of textile effluent.
Fulltext New approaches for Delaunay triangulation and optimisation

Perumal L

Heliyon, 2019 Aug;5(8):e02319.
PMID: 31517093 DOI: 10.1016/j.heliyon.2019.e02319

New techniques are presented for Delaunay triangular mesh generation and element optimisation. Sample points for triangulation are generated through mapping (a new approach). These sample points are later triangulated by the conventional Delaunay method. Resulting triangular elements are optimised by addition, removal and relocation of mapped sample points (element nodes). The proposed techniques (generation of sample points through mapping for Delaunay triangulation and mesh optimisation) are demonstrated by using Mathematica software. Simulation results show that the proposed techniques are able to form meshes that consist of triangular elements with aspect ratio of less than 2 and minimum skewness of more than 45°.
Fulltext Asexuality is inversely associated with positive body image in British adults

Swami V, Laughton R, Grover S, Furnham A

Heliyon, 2019 Sep;5(9):e02452.
PMID: 31538116 DOI: 10.1016/j.heliyon.2019.e02452

Research on positive body image has infrequently considered sexual minority orientations beyond lesbians, gay men, and bisexual persons. Indeed, there is no existing research on the relationships between body image and asexuality, which refers to a lack of sexual attraction to anyone or anything. In two studies, we rectified this by examining associations between asexuality - operationalised as a continuous construct - and indices of positive body image. In Study 1, 188 Britons from the community completed measures of asexuality and body appreciation. Once the effects of self-identified sexual orientation, relationship status, and body mass index (BMI) had been considered, asexuality was found to be significantly and negatively associated with body appreciation in women and men. In Study 2, an online sample of 377 Britons completed measures of asexuality, body appreciation, functionality appreciation, body acceptance from others, and body image flexibility. Beyond the effects of sexual orientation, relationship status, and BMI, asexuality was significantly and negatively associated with all four body image constructs in men, and with body appreciation and functionality appreciation in women. Although asexuality only explained a small proportion of the variance in positive body image (3-11%) and further studies are needed, the relationship appears to be stable.
Fulltext Toughness, elasticity and physical properties for the evaluation of foamed concrete reinforced with hybrid fibers

Dawood ET, Mohammad YZ, Abbas WA, Mannan MA

Heliyon, 2018 Dec;4(12):e01103.
PMID: 30603721 DOI: 10.1016/j.heliyon.2018.e01103

This study has been undertaken to investigate the evaluation of Fiber-reinforced Foamed Concrete (FRFC) performance by the use of toughness and non-destructive tests. These tests cover the workability, density, static modulus of elasticity, toughness, ultrasonic pulse velocity and absorption tests. Different FRFC mixes using carbon fibers in the order of 0.5, 1 and 1.5% carbon fibers were used. Also, the combinations of carbon fibers (C) and polypropylene fibers (PP) as 1% C+ 0.5% PP, and 0.5% C+1% PP were prepared. Lastly, the inclusion of polypropylene fibers with the order of 1.5% PP was used to strengthen the foamed concrete mix. The results showed that the use of 1.5% of C has affected the modulus of elasticity and flexural toughness of foamed concrete. On the other hand, a strong relationship is found between compressive strength and ultrasonic pulse velocity for FRFC.
Fulltext Inclusion of graphene on LDPE properties

Sabet M, Soleimani H

Heliyon, 2019 Jul;5(7):e02053.
PMID: 31334378 DOI: 10.1016/j.heliyon.2019.e02053

The spread of graphene in low-density polyethylene (LDPE) improves LDPE/graphene nanocompounds' thermal/mechanical/electrical characteristics. The images of scanning electron microscopy (SEM) verify full graphene exfoliation at 1000 °C. Inclusion graphene develops crystallinity; increases the local order of lattice and thermal stability of LDPE/graphene nanocompounds. The consistent distributions and further inclusion of graphene caused the great heat breakdown strength, increasing heat breakdown activation energy and a superior melting point (Tm) for LDPE nanocompounds. Percolation occurs with the graphene incorporation of 0.5 wt%. The complex viscosity test showed Newtonian behavior for LDPE at a very low frequency. But, graphene inclusion to LDPE changed the viscosity performance from liquid-like to solid-like which caused a decrease in the melt flow rate (MFR) values for all LDPE/graphene nanocompounds.
Fulltext Development of a NS2B/NS3 protease inhibition assay using AlphaScreen® beads for screening of anti-dengue activities

Abduraman MA, Hariono M, Yusof R, Rahman NA, Wahab HA, Tan ML

Heliyon, 2018 Dec;4(12):e01023.
PMID: 30560214 DOI: 10.1016/j.heliyon.2018.e01023

Background: Dengue infection is an endemic infectious disease and it can lead to dengue fever, dengue hemorrhagic fever, and/or dengue shock syndromes. Dengue NS2B/NS3 protease complex is essential for viral replication and is a primary target for anti-dengue drug development. In this study, a NS2B/NS3 protease inhibition assay was developed using AlphaScreen® beads and was used to screen compounds for their protease inhibition activities.
Methods: The assay system utilized a known NS2B/NS3 peptide substrate, a recombinant of NS2B/NS3 protease with proprietary StrepTactin® donor and nickel chelate acceptor beads in 384-well format.
Results: The optimized assay to screen for NS2B/NS3 protease inhibitors was demonstrated to be potentially useful with reasonable z' factor, coefficient variance and signal to background ratio. However, screening of synthesized thioguanine derivatives using the optimized AlphaScreen® assay revealed weak NS2B/NS3 inhibition activities.
Conclusion: The AlphaScreen® assay to screen for NS2B/NS3 protease inhibitors is potentially applicable for high throughput screening.
Trait driving anger and driving styles among Colombian professional drivers

Useche SA, Cendales B, Alonso F, Montoro L, Pastor JC

Heliyon, 2019 Aug;5(8):e02259.
PMID: 31440599 DOI: 10.1016/j.heliyon.2019.e02259

This study analyzes the association between trait driving anger and driving styles in a sample of Colombian professional drivers. Additionally, the internal and external validity of the Deffenbacher's Driving Anger Scale (DAS-14) was examined in the study population. The DAS-14 and the Spanish Version of the Multidimensional Driving Style Inventory (S-MDSI) were administered to 492 urban bus and taxi operators. Average trait driving anger scores in the study population were similar to those reported in previous validation studies from Spain, Argentina, China, and Malaysia. After deleting three cross-loaded items, confirmatory factor analyses revealed a three-dimensional latent structure for the DAS-14, similar but not equal to the previous Spanish speaking validations. This factorial structure fits the data reasonably well. Finally, linear regression analyses revealed that the three factors of the DAS-14 (impeded progress by others, illegal driving, and direct hostility) significantly predict adaptive and maladaptive driving styles. Overall, the results of this study suggest that the DAS-14 is a reasonably reliable measure of driving anger traits among professional drivers, and it also provides relevant insights for the prevention of risky driving styles in this occupational group.
Vision-based lane departure warning framework

Em PP, Hossen J, Fitrian I, Wong EK

Heliyon, 2019 Aug;5(8):e02169.
PMID: 31440587 DOI: 10.1016/j.heliyon.2019.e02169

Collisions arising from lane departures have contributed to traffic accidents causing millions of injuries and tens of thousands of casualties per year worldwide. Many related studies had shown that single vehicle lane departure crashes accounted largely in road traffic deaths that results from drifting out of the roadway. Hence, automotive safety has becoming a concern for the road users as most of the road casualties occurred due to driver's fallacious judgement of vehicle path. This paper proposes a vision-based lane departure warning framework for lane departure detection under daytime and night-time driving environments. The traffic flow and conditions of the road surface for both urban roads and highways in the city of Malacca are analysed in terms of lane detection rate and false positive rate. The proposed vision-based lane departure warning framework includes lane detection followed by a computation of a lateral offset ratio. The lane detection is composed of two stages: pre-processing and detection. In the pre-processing, a colour space conversion, region of interest extraction, and lane marking segmentation are carried out. In the subsequent detection stage, Hough transform is used to detect lanes. Lastly, the lateral offset ratio is computed to yield a lane departure warning based on the detected X-coordinates of the bottom end-points of each lane boundary in the image plane. For lane detection and lane departure detection performance evaluation, real-life datasets for both urban roads and highways in daytime and night-time driving environments, traffic flows, and road surface conditions are considered. The experimental results show that the proposed framework yields satisfactory results. On average, detection rates of 94.71% for lane detection rate and 81.18% for lane departure detection rate were achieved using the proposed frameworks. In addition, benchmark lane marking segmentation methods and Caltech lanes dataset were also considered for comparison evaluation in lane detection. Challenges to lane detection and lane departure detection such as worn lane markings, low illumination, arrow signs, and occluded lane markings are highlighted as the contributors to the false positive rates.
Fulltext Influence of inclined wall self-shading strategy on office building heat gain and energy performance in hot humid climate of Malaysia

Kandar MZ, Nimlyat PS, Abdullahi MG, Dodo YA

Heliyon, 2019 Jul;5(7):e02077.
PMID: 31360788 DOI: 10.1016/j.heliyon.2019.e02077

External shading geometry on buildings has been found to contribute substantially to reducing energy consumption for cooling. This study examines the effect of inclined wall self-shading strategy on heat gain in an office building. Field measurement of environmental variables such as ambient temperature, relative humidity, dew point, and wet bulb temperature was carried out in a case study inclined wall self-shading office building located in Putrajaya, Malaysia. The results of the validation of ApacheSim simulation software tool against the measured environmental variables indicated significant reliability having Pearson correlations ranging from 0.56 to 0.90. In establishing the relationship between different inclined wall strategies to the amount of heat gain, modification of the inclined wall self-shading projection (SSP) was modelled and experimented using ApacheSim simulation. Findings from the analysis revealed a relationship between heat gains into a building space and self-shading projection (SSP), as heat gains tend to reduce with increased SSP. From the findings, the optimum inclination angle of self-shading for effective heat gain reduction is based on a 45% self-shading projection. The application of inclined wall self-shading strategy in buildings would, therefore, bring about a reduction in heat gain, which invariably reduces energy consumption for cooling.
Fulltext Seasonal quality variation and environmental risks associated with the consumption of surface water: implication from the Landzun Stream, Bida Nigeria

Daramola J, M Ekhwan T, Adepehin EJ, Mokhtar J, Lam KC, Er AC

Heliyon, 2019 Jul;5(7):e02121.
PMID: 31384682 DOI: 10.1016/j.heliyon.2019.e02121

Water constitutes a major environmental and public health concerns worldwide. A large proportion of global water consumption is sourced from surface water. The dependency level on surface water is higher in developing countries, especially in rural-to-semi-urban areas, where subsurface water is not accessible. Presented in this paper is a spatiotemporal and hydrochemical quality assessment of the spring-originated Landzun Stream in Bida, Nigeria; which is usually consumed in its untreated state. Water samples were systematically collected in eighteen locations along the stream channel in both rainy and dry seasons at an equidistance interval of 500m. On-site and laboratory measurement of important physical and hydrochemical parameters were carried out using standard procedures. Water temperature in the rainy season (34-37 °C) slightly exceeds measured values in the dry season (29-33 °C). 72.22% (rainy) and 83.33% (dry) of collected samples did not meet the odourless requirement for drinking water. Similarly, estimated percentages of 66.67 and 94.44 of collected samples in rainy and dry seasons respectively have a taste. Contrary to data in the rainy season, 89%, 11%, 67% and 56% of the dry season's samples were enriched in magnesium (Mg), lead (Pb), potassium (K) and iron (Fe) respectively above the 2018 World Health Organisation guidelines for drinking water. This study further established that seasonal variation plays a major role in altering the aesthetic surface water quality. The intake of untreated surface water is a vehicle for potential water-borne diseases and allergies, hence alternative sources of drinking water for the populace dependent on the Landzun Stream is recommended to reduce risks and possible dangers of consuming the stream water.
Fulltext Phase behavior and fluid interactions of a CO2-Light oil system at high pressures and temperatures

Rezk MG, Foroozesh J

Heliyon, 2019 Jul;5(7):e02057.
PMID: 31384679 DOI: 10.1016/j.heliyon.2019.e02057

This paper investigates the phase behavior and mutual interactions between a light crude oil and CO2 at high pressures and high temperatures (HPHT). To do so, we have measured PVT properties of the CO2-oil system at HPHT using a PVT setup. We have also tried to present a detailed methodology for measuring PVT properties of CO2-oil systems and highlight the difficulties such as oil vaporization by CO2 during the experiments. A crude oil sample, collected from a Malaysian oil field, was used here. Our experiments indicated that, CO2 solubility in the oil increased at higher pressures when measured at a fixed temperature. Our experiments also showed that increasing the test temperature would reduce CO2 solubility in the oil, while its effect is more significant at higher pressures. The swelling factor (SF) measurements showed an increasing trend with pressure up to a certain value so-called extraction pressure, at which, the SF started to be reduced even became less than one. The measurements of oil viscosity indicated that CO2 dissolution in the oil sample could reduce the mixture viscosity up to 61%. The interfacial tensions between CO2 and the crude oil at different pressures were also measured while the results were used to estimate the minimum miscibility pressure (MMP) and the first contact miscibility (FCM) pressure. The IFT measurements at various pressures displayed a reduction trend as a result of more CO2 dissolution in the oil but with two different slopes. That is, at lower pressure values, the measured IFTs were sharply reduced with pressure, while the reduction rate of the IFT became less when pressures exceeded the extraction pressure. This study helps with determining the optimum pressure and temperature conditions of CO2-oil systems to have a minimum IFT, a maximum CO2 solubility and SF, and a minimum oil viscosity that are favorable for CO2-enhanced oil recovery projects. Additionally, the methodology presented here gives guidelines on how to design PVT experiments of CO2-oil systems for petroleum and chemical engineering applications.
Fulltext Estimating sediment yield at Kaduna watershed, Nigeria using soil and water assessment tool (SWAT) model

Daramola J, Ekhwan TM, Mokhtar J, Lam KC, Adeogun GA

Heliyon, 2019 Jul;5(7):e02106.
PMID: 31372557 DOI: 10.1016/j.heliyon.2019.e02106

Over the years, sedimentation has posed a great danger to the storage capacity of hydropower reservoirs. Good understanding of the transport system and hydrological processes in the dam is very crucial to its sustainability. Under optimal functionality, the Shiroro dam in Northern Nigeria can generate ∼600 MW, which is ideally sufficient to power about 404,000 household. Unfortunately, there have not been reliable monitoring measures to assess yield in the upstream, where sediments are sourced into the dam. In this study, we applied the Soil and Water Assessment Tool (SWAT) to predict the hydrological processes, the sediment transport mechanism and sediment yield between 1990 and 2018 in Kaduna watershed (32,124 km2) located upstream of the dam. The model was calibrated and validated using observed flow and suspended sediment concentration (SSC) data. Performance evaluation of the model was achieved statistically using Nash-Sutcliffe (NS), coefficient of determination (r2) and percentage of observed data (p-factor). SWAT model evaluation using NS (0.71), r2 (0.80) and p-factors of 0.86 suggests that the model performed satisfactorily for streamflow and sediment yield predictions. The model identified the threshold depth of water (GWQMN.gw) and base flow (ALPHA_BF.gw) as the most sensitive parameters for streamflow and sediment yield estimation in the watershed. Our finding showed that an estimated suspended sediment yield of about 84.1 t/ha/yr was deposited within the period under study. Basins 67, 71 and 62 have erosion prone area with the highest sediment values of 79.4, 75.1 and 73.8 t/h respectively. Best management practice is highly recommended for the dam sustainability, because of the proximity of erosion-prone basins to the dam.
Fulltext Snapshot of antimicrobial stewardship programs in the hospitals of Pakistan: findings and implications

Saleem Z, Hassali MA, Hashmi FK, Godman B, Ahmed Z

Heliyon, 2019 Jul;5(7):e02159.
PMID: 31384689 DOI: 10.1016/j.heliyon.2019.e02159

Objective: We are unaware of the extent of antimicrobial stewardship programs (ASPs) among hospitals in Pakistan, which is a concern given the population size, high use of antibiotics across sectors and increasing antimicrobial resistance (AMR) rates. Consequently, we sought to address this by undertaking a comprehensive survey.
Method: In this cross-sectional observational study in Punjab, an instrument of the measure was developed based on health care facility characteristics and ASPs after an extensive literature review. The questionnaire was circulated by mail or through drop off surveys to medical superintendents or directors/heads of pharmacy departments of hospitals.
Results: Out of 254, a total of 137 hospitals fully completed the questionnaire - 11 primary, 65 secondary, 46 tertiary and 15 specialized hospitals. The use of antimicrobial prescribing guidelines (68.7%), provision of infectious diseases consultation services (66.4%), clinical pharmacy service (65.7%), use of drug and therapeutics committees to approve antimicrobial prescribing (65.5%), regular audit by doctors on antimicrobial prescribing (54.1%) and use of a restricted formulary for antimicrobial (50.4%) were the most common ASPs. However, most of these activities were only somewhat or moderately successful. Whereas, electronic antimicrobial prescribing approval systems (15.3%), using a sticker to notify prescribers regarding the need to obtain approval for the antimicrobial prescribed (16.1%) and participation in the national antimicrobial utilization surveillance program (19.7%) were only seen in a few hospitals.
Conclusion: Study inferred that there are inadequate ASPs in the hospitals of Pakistan. A multidisciplinary approach, clinical leadership and availability of motivated and trained individuals are essential elements for the success of future ASPs.
Fulltext Fluid flow characteristics within an oscillating lower spherical surface and a stationary concentric upper surface for application to the artificial hip joint

Tso CP, Hor CH, Chen GM, Kok CK

Heliyon, 2018 Dec;4(12):e01085.
PMID: 30627676 DOI: 10.1016/j.heliyon.2018.e01085

The synovial fluid motion in an artificial hip joint is important in understanding the thermo-fluids effects that can affect the reliability of the joint, although it is difficult to be studied theoretically, as the modelling involves the viscous fluid interacting with a moving surface. A new analytical solution has been derived for the maximum induced fluid motion within a spherical gap with an oscillating lower surface and a stationary upper surface, assuming one-dimensional incompressible laminar Newtonian flow with constant properties, and using the Navier-Stokes equation. The resulting time-dependent motion is analysed in terms of two dimensionless parameters R and β, which are functions of geometry, fluid properties and the oscillation rate. The model is then applied to the conditions of the synovial fluid enclosed in the artificial hip joint and it is found that the motion may be described by a simpler velocity variation, whereby laying the foundation to thermal studies in the joint.
Fulltext Combating insolvency and business recovery problems in the oil industry: proposal for improvement in Nigeria's insolvency and bankruptcy legal framework

Olujobi OJ

Heliyon, 2021 Feb;7(2):e06123.
PMID: 33659729 DOI: 10.1016/j.heliyon.2021.e06123

Insolvency and business recovery laws in Nigeria have not evolved to incorporate reorganisation, reforming insolvent oil firms' operations to boost commercial oil firms' steadiness and economic suitability like other moderately developed countries. In Nigeria, liquidation is understood by many as the panacea to indebtedness. The research evaluates the Nigerian insolvency and business recovery legal regime to sustain indebted oil firms from economic shocks due to the global decline in the oil price to avert imminent business failures due to insufficient cash flows. The aim is to fill the gaps in Nigeria's insolvency and business recovery laws by recommending a model for the sustenance of oil firms and to suggest the reform of the gaps identified in the existing laws and the extant literature on the subject. The paper opted for conceptual legal review, comparative legal and policies analyses of solvency and business recovery legislations in Nigeria, Malaysia, India, South Africa, the United Kingdom and the United States. These nations were designated for this study because their insolvency and business recovery legal regime are business rescued driven, not winding up centred. The study is library research-based to address some of the flaws in Nigeria's insolvency and business recovery laws. The study finds that Nigerian legislation on insolvency is flawed in oil firms' salvage, improvement and rearrangement. It ends that, statutory bodies in the designated case study nations are efficient than those in Nigeria due to the strong political will of their governments in supporting insolvent oil firms for successful financial recovery, to safeguard jobs, to protect creditors and to enhance the wealth of their nations through sound business recovery policies and laws. The study, advocates, remodel of Nigeria's insolvency and business recovery legislations and policies in compliance with the international standards on insolvent oil firms salvaged and creditors focused policies for a robust economy. The study concludes with the recommendation for further study to consider quantitative analysis research methodology to project further scholarship on the subject.

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