A Superscan is described as a ‘beautiful bone scan’. In a superscan, the uptake of 99mTc-Methelene Diphosphonate (MDP) is prominent in the skeleton relative to soft tissue with absent or faint visualisation of the kidneys. This finding could be misinterpreted as a normal bone scan. A ‘Sub-superscan’ is a term used for scan findings in which the up- take is atypical of a superscan, but the patient has extensive bone metastases, as presented in our case report.
Emanuel syndrome, also referred to as supernumerary der(22) or t(11;22) syndrome, is a rare genomic syndrome. Patients are normally presented with multiple congenital anomalies and severe developmental disabilities. Affected newborns usually carry a derivative chromosome 22 inherited from either parent, which stems from a balanced translocation between chromosomes 11 and 22. Unfortunately, identification of Emanuel syndrome carriers is diffi- cult as balanced translocations do not typically present symptoms. We identified two patients diagnosed as Emanuel syndrome with identical chromosomal aberration: 47,XX,+der(22)t(11;22)(q24;q12.1)mat karyotype but presenting variable phenotypic features. Emanuel syndrome patients present variable phenotypes and karyotypes have also been inconsistent albeit the existence of a derivative chromosome 22. Our data suggests that there may exist ac- companying genetic aberrations which influence the outcome of Emanuel syndrome phenotypes but it should be cautioned that more patient observations, diagnostic data and research is required before conclusions can be drawn on definitive karyotypic-phenotypic correlations.
Introduction: Broken glass exhibits unique fracture patterns depend upon the nature of the impact. The fracture patterns provide information like point and angle of impact, direction of force and sequence of firing. Recent studies have shown that the use of shotgun in Malaysia is increasing, yet, the relationship existing among the fracture pattern and the projectile impact factors are not well documented. The objective was to analyse the fracture characteristics on different glass types of variable thickness and distance made by shotgun ammunition. Methods: Soda lime and tempered glass panel with dimension of 12’x 12’ with 3 or 4 mm thickness were shot from various distances of 4, 6 and 8 m from the muzzle end of the shotgun. Samples were analysed under fixed parameters and observations were recorded. Results: It is found that the bullet hole diameter of 4 mm tempered glass were larger compared to 4 mm soda lime glass ranged from 14.33 to 24.17 cm as distance increased. Tempered glass surface also exhibited dicing fragments unlike soda lime glass where only radial fracture patterns are evident. This can be attributed to high inherent strength and ductility that makes the tempered glass remarkably resistant to external force. Conclusion: The findings from this study can lead to distinguish the type of glass through examination of fracture patterns, whether it is soda lime silica or tempered glass. The type of glass and the source of impact can be determined using the fragments, no reconstruction necessary.
Abstracts For The 1st International Borneo Healthcare And Public Health Conference And 4th Borneo Tropical Medicine And Infectious Disease Congress. Held at the Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia On 3rd-5th September 2019
Introduction: Laboratory screening tests are common elements of health care. Comprehensive care of patients is dependent on the results of laboratory investigations. Dissemination of knowledge and improving attitude of com-munity for utilization of laboratory services are utmost important in community health care. This study aimed to assess the knowledge and utilization of the laboratory services among the employees of University Malaysia Sabah, determine their expectations of employees on the medical laboratory services.
Methods: A total of 200 UMS staff participated. The data were collected using a cross-sectional self-administered questionnaires and descriptive data analysis was done.
Results: 5% of the participants in this study agreed to have the health check and blood screening tests every year. Less than 10% of respondents agreed to do more frequent blood tests check if they are at high risk such as family history of cancer, hypertension and diabetes 181 out of 200 respondents do not agree that doing laboratory tests can help for early diagnosis of some diseases. The most used laboratory tests were plasma sugar (70.8%), blood grouping (60.4%), urine examination (50%) and serum lipid (46%).
Conclusion: Based on the results, recommendations were made to improve the knowledge, attitude and utilization of the laboratory services and set up laboratory services easily accessible by the university community. This will lead to positive health benefits in people and improve associated health outcomes.
Abstracts For The 1st International Borneo Healthcare And Public Health Conference And 4th Borneo Tropical Medicine And Infectious Disease Congress. Held at the Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia On 3rd-5th September 2019
Introduction: Cancer is a major public health problem and the third leading cause of death in Malaysia. Ovarian cancers are the fifth most common cancer among women in Peninsular Malaysia. Our aim is to assess the risk factors in healthy young adult female students from UMS and will act as an input for further prevention of ovarian cancer. Methods: Cross sectional, questionnaire-based study was done on total 278 Medical and Nursing students from Faculty of Medicine and Health Sciences and received the answers based on genetic assessment of ovarian cancers whether gives positive history of ovarian cancers in first degree, second degree and third-degree relatives. The life-time risk of a woman who has a first degree relative with ovarian cancer is five percent (the average woman’s lifetime risk is 1.4 percent). Results: Assessing the hereditary risk factor, total 1.8% gives positive results for ovarian cancer in first degree relatives. The lifetime risk of ovarian cancer among female mutation carriers was 39-46% for BRCA1 and 12-20% for BRCA2 mutation carriers. In our study, regarding physical activity,63.7% is not meeting with WHO recommendation for Metabolic Equivalent Task (MET) and remaining 36.3% meets WHO recommendation. By using International Physical Activity Questionnaire (IPQA)Score Protocol, only 2.6 % of Medical students showed Health Enhancing Physical Activity (HEPA) active,36.4 % showed minimally active and 60.9% showed inactive. Among nursing students only 5.5% showed HEPA active, 35.4% showed minimally active and 59.1% are inactive. Conclu-sion: Primary prevention through behavioural and lifestyle modification is a cost-effective means of preventing the large burden cancer has on societies world-wide.
Introduction: Pineapple harvesting work contributes to the reporting of musculoskeletal symptoms (MSS) and er- gonomic risks. Pineapples are harvested manually in some parts of Malaysia using rattan baskets and workers are exposed to excessive bending, pain and discomfort. This intervention study developed and tested a prototype of an ergonomic harvesting basket to potentially reduce discomfort and physiological workload during a simulation of har- vesting activity. Methods: The development and testing of improved harvesting basket was performed in laboratory and workshop. The improved basket had adjustable cushion straps, foam back pad and an opening for unloading of fruits. Harvesting was simulated using improved and existing basket by human subjects and questionnaires were used to assess discomfort. Physiological workload was assessed by heart rate and energy expenditure. Results: A total of 12 male respondents with average age of 22.4 (2.2) years participated in harvesting simulation. Discomfort as measured in Likert scale (mean (standard deviation) for improved basket 4.13 (6.1) vs existing basket 12.26 (11.2); p
Introduction: An experimental study was conducted to determine the effects of synthetic chemical artificial toxic sugar bait (ATSB) on adult Aedes albopictus population in a controlled environment. The method uses an “attract and kill” concept and makes use of mosquito’s sugar-feeding behaviour. Formulations of ATSB consists of natural scents as an attractant, a sugar solution as a feeding stimulant and an oral toxin such as boric acid to eliminate mos- quito population. Methods: The experiment was conducted in two phases; (i) the first phase aimed to determine the optimum sucrose concentration (10%, 30%, 50% and 70%) that will elicit the highest biting and fecundity rates in female mosquitoes and (ii) the second phase aimed to identify the ATSB, optimum sucrose from phase one incorpo- rated with boric acid (0.1%,0.5% and 1%), that cause the highest mortality rates of adult female Aedes albopictus in a laboratory environment. Results: Seventy percent sucrose concentration was selected as the optimum sucrose concentration because the ingestion of the solution cause the highest biting and fecundity rates in mosquito compare to other sucrose concentrations. Meanwhile, 1% boric acid resulted in the highest mortality rate within two days of the experiment period. Conclusion: This study has identified the optimum sucrose concentration required to attract adult mosquitoes and highlighted the efficacy of 1% boric acid as an effective mosquito adulticide. The findings highlight the potential of ATSB as a valuable vector control method which could be further developed for future use.
Introduction: Work-related road traffic crashes (RTC) are a significant global public health challenge due to the seriousness of its consequences. Injured workers who have survived work-related RTC are advised to go for reha- bilitation after they have been treated physically by healthcare providers. Reintegrate as soon as possible into the working community able avoid long periods of sick leave. Return to work (RTW) rate have been used extensively in many previous studies as an indicator of rehabilitation outcomes on the working capacity of injured workers. The objective of this study was to compare RTW rate after rehabilitation for injured workers who received physical re- habilitation only (control group) and physical rehabilitation plus outcome-focused intervention (intervention group). Methods: Eligible 200 workers who were involved in work-related RTC and agreed to participate in SOCSO RTW Program were identified and invited to be part of this study. Sociodemographic, employment and injury-related questions were distributed. Results: This study finding showed majority (79.5%) of the respondents were aged 25 years old or older, male (86.0%), married or divorced (63.5%), and attained secondary and below education level at secondary or below (66.0%). More than half of injured workers consisted of blue-collar workers (69%), had fracture injury (93.0%), and had injury to their lower limbs (48.5%). RTW rate was higher in the intervention group (received physical rehabilitation and outcome-focused intervention) compared to the control group (received physical rehabil- itation only). Conclusion: RTW rate for work-related RTC was higher with outcome-focused intervention, in addition to physical rehabilitation.
Introduction: Vector surveillance in high-rise buildings is important to predict and monitor the presence of vectors regarding their abundance and distribution. In this study, the infestation profile of Aedes aegypti and Aedes albopic- tus species in different environmental settings were investigated. Methods: Four high-rise apartments in four differ- ent localities were selected for ovitrap surveillance. Fifty ovitraps were placed in semi indoor and outdoor settings. Results: A total of 507 (42.8%) from ovitraps showed the presence of the Aedes species larvae. Out of these, 170 (33.5%) of the positive ovitraps were those placed in semi indoor and 337 (66.5%) in outdoor. Of the total 16,613 Aedes larvae found, 4,130 (24.9%) were from semi indoor, and 12,483 (75.1%) from outdoor. In terms of distri- bution, Ae. albopictus was predominantly found in outdoor environments (POI=87.5%; MLT=36.45 larvae). Ae. aegypti was also found in outdoor environments (POI=14.89%; MLT=8.26 larvae). There was a significant difference in POI for both Ae. aegypti and Ae. albopictus in the two different environments but no significant difference was observed in MLT, indicating that the density of the Aedes species in both environments was well distributed. Con- clusion: In this study, the patterns of Aedes habitat in high-rise apartments were observed. This study has shown an invasion and adaptation of Aedes mosquitoes into the ecosystems of high-rise buildings. It can be concluded that housing designs and the condition of the surrounding environment affects the infestation profile and the distribution of Aedes mosquitoes.
Introduction: Innovative ways of balancing indoor relative humidity without compensate for the optimal working environment is crucial as excessive dampness is a risk factor for health symptoms among people and deteriorate building performance. This study examines the potential of fabricating humidity controlling material by sintering a mixture of diatomite, waste glass and cockle shell powder. Moisture sorption isotherms, moisture buffer values, pore structure, surface morphology and flexural strength of the final products were determined. Methods: Mixture of diatomite, powdered waste glass and cockle shell powder is mixed at different ratio, pressed and sintered at 1100°C for 20 minutes. The final products were examined using nitrogen gas adsorption-desorption and scanning electron microscopy for mesoporous and morphology properties. The moisture adsorption-desorption performances of the samples were tested using desiccator method while the flexural strength is tested using universal testing machine. Results: The sintered products have specific surface area from 5.744 m2/g to 14.765 m2/g and have pore size from 39.5-67.7 nm. The best product, manufactured by mixing 60% diatomite, 30% waste glass and 10% cockle shell powder, showed a good moisture buffer value (MBV: 1.3 g/m2 %RH) and flexural strength of 8.23 ± 1.8 MPa satisfy the standard of those commercial porous ceramics. Conclusion: Usage of waste glass and cockle shell powder in development of humidity control material helped in the waste reduction. The humidity control material produced can regulate indoor humidity without additional energy consumption. The superior products show excellent charac- teristics and highly promising for various construction applications.
Introduction: The survivorship of mosquito is the most important aspect that affects its ability as a pathogen trans- mitting vector such as Aedes albopictus which is a vector of dengue. In this study, temperature stress effect on the survival of adult Aedes albopictus were investigated. Methods: It was conducted by manipulating different constant temperatures (15°C to 35°C) on juvenile stage of Ae. albopictus in natural and artificial container. Then, the devel- opment growth of adult mosquito was observed under laboratory condition. The effects of exposed temperature on certain biological parameters of adult mosquito were evaluated in terms of survival rates, longevity of female mosquito, fecundity rate, gonotrophic cycle and wing length of the adult mosquito. Results: In higher temperatures, the longevity of adult female was reduced and the highest longevity was found at optimum temperature (25°C) with average of 8.6 ± 0.18 days and 6.7 ± 0.29 days in natural and artificial container respectively. Both sexes showed a clearly tendency towards decreasing survivorship with increasing temperature where the highest survival was found at 15°C. Conversely, survival was lowest at a high temperature (30°C to 35°C). This study also showed that the wing length of both sexes was significantly affected by the rearing temperature where the longest found at 15°C and the shortest at 35°C. Conclusion: Thus, this study provide useful information of mosquito ecology in response to varia- tion of temperatures.
Introduction: An assessment of dermal exposure to pesticide mixtures among sprayers was made as a function of crop type, in four agricultural subsectors in Malaysia. Methods: The potential and actual dermal exposures for 160 pesticide sprayers performing pesticide spraying task were estimated by using Dermal Exposure Assessment Method (DREAM). Results: Results showed that there was significant difference between nationality (p
Introduction: Noise was evident to reduce job satisfaction among workers which will negative impacts to workers including increase job turnover, decrease motivation and increased number of accidents. This study aims to explore job satisfaction and its risk factors among workers working in a noisy workplace. Method: The study design was cross-sectional study which involved 167 workers in a cable manufacturing factory selected by simple random sam- pling. MSQ was used to assess employee’s satisfaction with their job on seven facets and sound level meter was used to measure workplace noise level. Results: All respondents were exposed to noise above permissible exposure limit. Most workers (49%) were moderately satisfied with their work. Factors that were rated as lowest level of satisfaction were work itself (the ability to work alone) (40%) and the way company system policies are implemented (40%). Factors with the highest level of satisfaction were their freedom to implement their judgement (responsibility) (51%) and the supervision quality of their superiors (51%). The most dominant facet predicting total satisfaction level was recognition followed by advancement and company policy and administration. All variables in socio-demographical and job characteristics were not significantly associated with their level of job satisfaction except noise. Noise was significant in predicting one facet of job satisfaction which was physical work condition. Conclusion: Overall, the average level of job satisfaction among respondents were moderate and they were exposed to occupational noise which was the only significant study variable correlated with their job satisfaction.
Introduction: Water based Metalworking fluids (MWF) are commonly used in machining industries and are excellent media for microorganism growth. The study aimed at determining the relationship between the airway inflammation as indicated by fractional exhaled nitric oxide (FeNO) with the microbial contaminants of MWF in aerosol and bulk sample as well as the workers’ reported respiratory health symptoms. Methods: This cross sectional study was carried out on 138 machining workers. Their FeNO were measured using NIOX-MINO instrumentation. The microbial as- sessments of bacteria and fungus were carried out on the MWF bulk samples and the aerosol using a sampler DUO SAS SUPER 360TM. Results: Findings showed significant difference in the FeNO levels in workers from various job sections (p=0.01). Significant relationships found between high FeNO levels with their closeness to the machines (p=0.03), high number of machines in the workplaces (p=0.02), high environmental bacteria colonies (p=0.04), lon- ger employment years (p
Discomfort measurement has usually been attempted by asking the participants to rate the scale of their discomfort which commonly termed as a subjective scale. Various studies had conducted the discomfort level on vehicle seat by using Visual Analogue Scale (VAS) and Likert scale. VAS is a tool that use to measure a discomfort or characteristics in range across a continuum of values. Meanwhile, Likert-scale is a tool consist of items that require respondents to rate their degrees of comfort or discomfort with various declarative statements. Thus, the purpose of this study is to review, discuss and compare between the VAS and Likert scale used on the development and assessment of sitting discomfort survey in seat vehicles. The literature on various topics related to questionnaire development on discomfort in seat vehicle were collected from electronic databases. Four high-quality studies were eligible and met the inclusion and exclusion criteria. Overall, there is no evidence and conclusion that neither visual analogue scale nor Likert scale are better to one another. Therefore, it can be concluded that either of this scale still applicable for the ergonomic research application as both of this scale have their own pros and cons.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants with toxic effects and adverse health impacts on general population. Several methods of extraction had been applied to extract PAHs from human blood samples such as solid phase extraction (SPE). The SPE represents one of the most common techniques for extraction and clean-up procedures as it needs low quantity of solvents with less manual efforts. Similarly, various analytical instruments like gas chromatography coupled to mass spectrometry (GC-MS) was used to measure the PAHs levels. Gas chromatog- raphy is a simple, fast, and very efficient method for solvents and small organic molecules. This review provides an overview of the measured concentrations of PAHs in human blood samples through the application of SPE and GC- MS during the last ten years. While these studies used various solvents, their application of SPE method and GC-MS revealed rewarding results about the determination of PAHs levels in the human samples.
Exposure to traffic related air pollution (TRAP) is a public health concern particularly in children, who are one of the most susceptible groups of the population. Children are more vulnerable to such exposure by virtue of their increased susceptibility and the higher doses received. The materials for this review was obtained from several online databas- es; PubMed, Proquest, Scopus, Springerlink and Science Direct (year 1990 to 2018). In this review, we emphasized several relevant studies on respiratory health effects among children living in the proximity to heavy traffic area and focus on the factors, which contributed to the severity of the health outcomes. Short term TRAP exposure reduces lung function, increases respiratory symptoms and incidence of asthma and allergic diseases especially for those who living within 75 m from the heavy traffic area. Preventive measures must be taken in order to protect children from exposure to traffic air pollutants.
Agriculture activity in Cameron Highland is one of the sources of river water pollution. This study evaluates the phys- icochemical properties and heavy metals contamination (Cu, Cd, Zn, Cr, Pb) in Bertam River. The results indicate the river water pH was slightly acidic. Based on the Malaysia National Drinking Water Quality Standard (NDWQS), the river water is not suitable for drinking as it has exceeded the safe value for turbidity, chemical oxygen demand COD and lead (Pb). Spatial distribution of heavy metals showed that Cr, Cu and Pb were concentrated at the downstream area.
In Malaysia, chemical pesticides are widely used not only for agricultural development, but also to public health, household to control diseases, pests or weeds. In order to ensure that the information of the pesticides’ hazard prop- erties conveyed to all pesticide users, the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) has initiated to promote standard criteria for classifying chemicals according to human health, physical and environmental hazards. Even though statuses of GHS implementation on pesticides are remained unstandardized across different countries, Malaysia has taken proactive measures to implement the GHS at the workplace through the promulgation of the Occupational Safety and Health (Classification, Labelling and Safety Data Sheet of Hazard- ous Chemicals) Regulations 2013 (CLASS Regulations). This paper attempted to summarize the health hazards of pesticide chemicals registered in Malaysia by summarizing the nature of the registered pesticides’ hazards classifica- tion based on GHS in order to understand the current situation of GHS adoption in pesticides sector in the country. Overall, registered pesticides in Malaysia are known to cause either acute or chronic health effects. Out of 3,610 pesticides registered under the Pesticide Board, a total of 2,241 pesticides are listed as highly hazardous pesticides (HHP). Even though GHS includes appropriate labelling tools to convey information about each of the hazard classes and categories, several limitations have found when classifying appropriate hazard class and categories to individual pesticides.
Introduction: Eating seafood has become a major health concern for many people due to the present of heavy met- al especially cadmium (Cd). Cd can accumulate in the body and disrupt the normal cellular processes which will eventually lead to organ damage. This study aims to determine the seafood consumption pattern and blood cadmium (BCd) as well as the association between these two variables among respondents living along the coastal area of Melaka. Methods: Pretested questionnaires were used to collect background and food frequency intake from coastal villagers through convenient sampling method. Venous blood samples were analysed by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for BCd determination. Results: A total of 63 respondents who 54% were female with median age of 34 years old provided complete data in this study. The most frequently consumed seafood and its product were shrimp paste (31.5%) followed by mackerel (13.6%), hardtail-scad (6.2%), flatfish (4.5%) and fish ball (4.0). All blood samples showed the present of Cd with median (IQR) = 0.076 (0.1) μg/L and ranged between 0.007 to 1.284 μg/L. The finding showed no association between frequently consumed seafood and low BCd of the respondents. On the other hand, gender was found to be significantly associated with the BCd. Conclusion: Seafood consumption pattern was not significantly associated with BCd which suggests that frequent seafood consumption may not contribute much to BCd level among the respondents as well as it may indicates safe consumption of these seafood available in the study location.