MyMedR

Biosocial variances and infant survival: a path analysis approach

Frisch AS, Kallen DJ, Griffore RJ, Dolanski EA

J Biosoc Sci, 1992 Apr;24(2):175-83.

This study used path analysis to assess the chances of survival of babies in a neonatal intensive care unit in Lansing, Michigan, USA. Two paths to neonatal survival were identified and the variables accounted for 20% of the variance in gestational age. The first path showed that prior infant losses were negatively correlated with gestational age while in the second path, gestational age showed negative relationships with pre-pregnancy weight and household job worries.

Matched MeSH terms: Infant, Newborn; Infant, Premature, Diseases/etiology; Infant, Premature, Diseases/mortality*

Fulltext Use of steroids sparingly especially in children

Ng LF

Med J Malaysia, 1985 Jun;40(2):142.

PMID: 3834286

Matched MeSH terms: Infant, Newborn

Effect of continued feeding of cows' milk on asymptomatic infants with milk protein sensitive enteropathy

Iyngkaran N, Yadav M, Boey CG, Lam KL

Arch Dis Child, 1988 Aug;63(8):911-5.

PMID: 3415326

The clinical response and the histological changes in the mucosa of the small bowel in response to continued feeding with cows' milk protein were assessed over a period of 2-6 weeks in 24 infants who had shown histological changes without immediate clinical symptoms after challenge with a diet containing cows' milk protein. Twenty of the 24 infants (83%) thrived well on cows' milk protein. Jejunal biopsy specimens taken six to eight weeks after the initial biopsy showed histological improvement in all 20 infants compared with biopsy specimens taken soon after the challenge, which had shown mucosal damage. The mucosa had returned to normal in 12, was mildly abnormal in seven, and moderately abnormal in one. Corresponding improvements in the activities of mucosal enzymes were seen. In four of the 24 infants (17%) symptoms developed between three and six weeks. Histological examination of the jejunal biopsy specimens showed that mucosal damage had progressed in two, and remained the same in two; moreover, the disaccharidase activities remained depressed. The present study shows that most infants with enteropathy caused by sensitivity to cows' milk protein but without clinical symptoms develop tolerance to the protein and the mucosa returns to normal despite continued feeding with cows' milk protein.

Matched MeSH terms: Infant; Infant Nutritional Physiological Phenomena*; Infant, Newborn

Birth trauma and nasal septal deformity in neonates

Saim L, Said H

J Singapore Paediatr Soc, 1992;34(3-4):199-204.

PMID: 1305661

The prevalence of nasal septal deformity and its relationship with the different types and difficulty of delivery were studied in a randomised group of newborns at the Maternity Hospital Kuala Lumpur between 1st November 1989 to 31st January 1990. Out of a total of 674 noses examined using the otoscope, 147 (21.8%) were found to have nasal septal deformity. There was no significant difference in the prevalence of nasal septal deformity in the different types of delivery. There was also no significant increase in the prevalence of nasal septal deformity with increasing degree of difficulty of the delivery. Therefore, we cannot then attribute parturition pressures or birth trauma as the etiology of these congenital nasal septal deformity. Nevertheless a policy of routine screening in view of early correction is advocated to decrease the morbidity associated with this deformity in newborns and children.

Matched MeSH terms: Infant, Newborn

Infant mortality decline in Malaysia, 1946-1975: the roles of changes in variables and changes in the structure of relationships

DaVanzo J, Habicht JP

Demography, 1986 May;23(2):143-60.

PMID: 3709892

This analysis has identified several factors contributing to the dramatic decline in infant mortality since World War II in Malaysia, as well as one factor that prevented the infant mortality rate from declining even more rapidly. Our main findings are the following: On average, mothers' education more than doubled over the study period, contributing to the decline in their infants' mortality. In addition, the beneficial effect of mothers' education on infant survival appears to have become stronger over the study period. Hence, further advances in education should lead to further improvements in infants' survival prospects. Another analysis of these data (Peterson et al. 1985) found that education is somewhat more influential in affecting child mortality in low-mortality, high-income areas than in the opposite type of areas. Therefore, socioeconomic development may have complemented, instead of substituted for, the the beneficial effect of mothers' education in promoting infant and child survival in Malaysia. Improvements in water and sanitation also contributed to the infant mortality decline, especially for babies who did not breastfeed. However, unlike education, these influences have become less important over time, especially for babies who are not breastfed. Hence, further improvements in water and sanitation, a goal of Malaysia's Rural Environmental Sanitation Programme, may have smaller relative effects on infant mortality than did previous improvements. Targeting such improvements on areas where women breastfeed little or not at all, however, will increase their effectiveness in promoting infant survival. The substantial reductions in breastfeeding that have taken place since World War II have kept the infant mortality rate in Malaysia from declining as rapidly as it would have otherwise. We estimate that, in our sample, the detrimental effects on infant survival of the decline in breastfeeding have more than offset the beneficial effects of improvements in water and sanitation. Unlike some other researchers (e.g., Palloni 1981), we find that changes in fertility levels and in the timing and spacing of births have had negligible effect in explaining the decline in infant mortality within the samples we have considered. We have excluded births to older women from our analysis, however; this exclusion may have led to an understatement of the influence of changes in the age pattern of childbearing.(ABSTRACT TRUNCATED AT 400 WORDS)

Matched MeSH terms: Infant; Infant Mortality*; Infant Nutritional Physiological Phenomena

Fulltext Gaucher's disease type 1A: a case report

Nunis GV

Med J Malaysia, 1985 Sep;40(3):257-9.

PMID: 3842723

A child with massive hepatosplenomegaly was diagnosed on bone marrow biopsy to have Gaucher's disease. The clinical progress in this form of Gaucher's disease is highlighted and the clinical diagnosis correlated with published criteria.

Matched MeSH terms: Infant

Neonatal septicaemia in Kelantan, Malaysia

Choo KE, Wan Ariffin WA, Chua SP

Ann Acad Med Singap, 1988 Jul;17(3):438-42.

PMID: 3218934

A retrospective study of 84 cases of neonatal septicaemia admitted into a neonatal unit in a rural area of Malaysia for 1 year between 1st September 1985 to 31st August 1986 was carried out to determine the spectrum of micro-organisms and predisposing factors in relation to early and late onset septicaemia. The incidence of neonatal septicaemia was 2.13 per 1,000 live-births per year and the case fatality was 41.7% with higher case fatality in those who were premature, those who presented as early onset and those who had gram negative septicaemia. The mean age of onset of septicaemia was 7.8 days (range from 2 hours to 27 days). Forty four (52%) neonates had early onset septicaemia with mean age of onset at 2.7 days; forty (48%) neonates had late onset septicaemia presenting at 13.6 days of life. Gram negative organisms such as Klebsiella, Pseudomonas, sp., E. coli and Streptococcus, especially group B Streptococcus were the major organisms in the early onset septicaemia. Staphylococcus aureus and Staphylococcus epidermidis were the major organisms responsible for the late onset septicaemia. Obstetrical factors played an important role in early onset septicaemia. Prematurity was the most common predisposing factor. Invasive diagnostic and therapeutic procedures including surgery highlighted once again the importance of these procedures in predisposing the newborn to infection.

Matched MeSH terms: Infant, Newborn; Infant, Premature, Diseases/microbiology*; Infant, Premature, Diseases/mortality

Fulltext Sickle cell anaemia in pregnancy: a case report

Rachagan SP, Raman S, Cherian R

Med J Malaysia, 1984 Sep;39(3):243-5.

PMID: 6544928

To our knowledge, sickle cell anaemia in pregnancy has not been reported in Malaysia. We describe here such a case with emphasis on modern methods of management.

Matched MeSH terms: Infant, Newborn

Margosa oil poisoning in India and Malaysia

Sinniah D, Baskaran G, Vijayalakshmi B, Sundaravelli N

Trans R Soc Trop Med Hyg, 1981;75(6):903-4.

PMID: 7330956

Matched MeSH terms: Infant

Infant feeding practices among nursing personnel in Malaysia

Sinniah D, Chon FM, Arokiasamy J

Acta Paediatr Scand, 1980 Jul;69(4):525-9.

PMID: 7446101

Concerned by the alarming decline in breast feeding in the urban and rural areas of Malaysia, we conducted a critical review of infant feeding practices among nursing personnel from representative centres using questionnaires. It was found that although 75% of mothers breast-fed their babies at birth only 19% did so at 2 months and 5% at 6 months respectively. Chinese mothers initiated breast feeding less frequently compared with Indian or Malay mothers. The prevalence of breast feeding was higher among lower category nurses, lower income groups and those from health centres. Decision for breast feeding was based in most instances on conviction derived from reading, lectures or advice from relatives. The vast majority of mothers listed "work' as the main reason for termination of breast feeding followed by "insufficient breast milk' and satisfactory past experience with bottle feeding. The ramifications of these findings and measures to improve the prevalence and duration of breast feeding are discussed.

Matched MeSH terms: Infant; Infant Nutritional Physiological Phenomena*; Infant, Newborn

The impact of child mortality on spacing by parity: a Cox-regression analysis

Lehrer E

Demography, 1984 Aug;21(3):323-37.

PMID: 6479392

Child mortality may affect spacing through biological and behavioral channels. The death of a child may elicit a desire to have another one soon; further, it may interrupt breastfeeding and shorten the sterile period following childbirth. The hypothesis that the child mortality-spacing linkage varies across parities, being strongest in the middle parities, is examined using microdata from Malaysia and the Cox-regression technique. The empirical results lend support to the hypothesis.

Matched MeSH terms: Infant; Infant Mortality*; Infant, Newborn

Congenital duplication of the gall bladder: review of the literature and report of a case

Ramanathan T

Med J Malaya, 1971 Jun;25(4):305-6.

PMID: 4261308

Matched MeSH terms: Infant, Newborn

An infant oesophageal stethoscope

Liew RP, Him YK, Jin CU

Med J Malaysia, 1975 Mar;30(3):234.

PMID: 1160686

Matched MeSH terms: Infant

Neonatal hyperbilirubinaemia

Sinniah D

Med J Malaya, 1971 Mar;25(3):211-4.

PMID: 4253249

Matched MeSH terms: Infant, Newborn; Infant, Newborn, Diseases/epidemiology*; Infant, Premature, Diseases

Fulltext Cutis Marmorata Telangiectatica Congenita Associated with Hemiatrophy

Leung AKC, Lam JM, Leong KF

Case Rep Pediatr, 2020;2020:8813809.

PMID: 33101749 DOI: 10.1155/2020/8813809

Cutis marmorata telangiectatica congenita is characterized by the presence of a bluish-purple reticulated cutaneous vascular network on the skin intermixed with telangiectasia and occasionally prominent veins at birth. Areas of the skin within the reticulated cutaneous vascular network may be normal, erythematous, atrophic, and, at times, ulcerated. Areas of ulcerations and focal cutaneous and subcutaneous atrophy occasionally occur resulting in body asymmetry. On the other hand, cutaneous and subcutaneous atrophy, extensive and severe enough leading to hemiatrophy, of the entire limb is rare. A search of the English literature revealed only eight documented cases to which we are adding two more cases.

Matched MeSH terms: Infant, Newborn

Non-syndromic craniosynostosis treated by frontal orbital advancement: A case report

Khoo KW, Arman Zaharil MS, Mohd Ali MZ

Med J Malaysia, 2018 12;73(6):423-424.

PMID: 30647221

Craniosynostosis is a premature pathologic fusion of one or more cranial vault sutures leading to abnormally-shaped skull. It can occur in isolated event (non-syndromic), or it can occur in conjunction with other anomalies in welldefined patterns (syndromic). The diagnosis rests on clinical examination and confirmation is generally on the computed tomography scan. The need for surgery is both for cosmetic and functional reasons. Here we describe a case of nonsyndromic craniosynostosis that was treated with frontal orbital advancement (FOA). The potential benefits of FOA need to be carefully weighed against the potential complications when deciding for any surgical intervention.

Matched MeSH terms: Infant

Notes on a case of infantile ascariasis

Scharff JW

Malayan Medical Journal, 1926;1:3.

Matched MeSH terms: Infant

Fulltext Aplasia Cutis Congenita as a Sole Manifestation of Congenital Varicella Syndrome

Leung AKC, Leong KF, Lam JM

Case Rep Pediatr, 2020;2020:6147250.

PMID: 32774973 DOI: 10.1155/2020/6147250

Aplasia cutis congenita following maternal varicella is well known. On the other hand, aplasia cutis congenita as the sole manifestation of congenital varicella syndrome is very rare. A perusal of the literature revealed only one case. We report two infants with aplasia cutis congenita as the sole manifestation of congenital varicella syndrome.

Matched MeSH terms: Infant

Late onset infection in very low birth weight infants in Malaysian Level 3 neonatal nurseries. Malaysian Very Low Birth Weight Study Group

Ho JJ

Pediatr Infect Dis J, 2001 Jun;20(6):557-60.

PMID: 11419494

The purpose of this study was to examine the rate and mortality from late onset infection occurring in very low birth weight infants admitted to Malaysian nurseries.

Matched MeSH terms: Infant Mortality; Infant, Low Birth Weight*; Infant, Newborn

Optimising bone health among older people with hip fractures and co-existing advanced chronic kidney disease

Ong T, Yong BKA, Shouter T, Shahrokhi N, Sahota O

Eur Geriatr Med, 2020 08;11(4):635-638.

PMID: 32488688 DOI: 10.1007/s41999-020-00340-z

PURPOSE: Patients with a hip fracture and co-existing advanced chronic kidney disease (CKD) are at risk of further fractures due to either CKD-mineral bone disease or osteoporosis.

METHODS: An analysis of a hospital's hip fracture service registry of patients ≥ 60 years with CKD stage 4 (15-29 ml/min/1.73m2) or stage 5 (

Matched MeSH terms: Infant, Newborn

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