Displaying publications 221 - 240 of 546 in total

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  1. Label-free Quantitative Proteomic Analysis of Ascorbic Acid-induced Differentially Expressed Osteoblast-related Proteins in Dental Pulp Stem Cells from Deciduous and Permanent Teeth
    Zainol Abidin IZ, Manogaran T, Abdul Wahab RM, Karsani SA, Yazid MD, Yazid F, et al.
    Curr Stem Cell Res Ther, 2023;18(3):417-428.
    PMID: 35762553 DOI: 10.2174/1574888X17666220627145424
    BACKGROUND: Proteomic is capable of elucidating complex biological systems through protein expression, function, and interaction under a particular condition.

    OBJECTIVE: This study aimed to determine the potential of ascorbic acid alone in inducing differentially expressed osteoblast-related proteins in dental stem cells via the liquid chromatography-mass spectrometry/ mass spectrometry (LC-MS/MS) approach.

    METHODS: The cells were isolated from deciduous (SHED) and permanent teeth (DPSC) and induced with 10 μg/mL of ascorbic acid. Bone mineralisation and osteoblast gene expression were determined using von Kossa staining and reverse transcriptase-polymerase chain reaction. The label-free protein samples were harvested on days 7 and 21, followed by protein identification and quantification using LC-MS/MS. Based on the similar protein expressed throughout treatment and controls for SHED and DPSC, overall biological processes followed by osteoblast-related protein abundance were determined using the PANTHER database. STRING database was performed to determine differentially expressed proteins as candidates for SHED and DPSC during osteoblast development.

    RESULTS: Both cells indicated brownish mineral stain and expression of osteoblast-related genes on day 21. Overall, a total of 700 proteins were similar among all treatments on days 7 and 21, with 482 proteins appearing in the PANTHER database. Osteoblast-related protein abundance indicated 31 and 14 proteins related to SHED and DPSC, respectively. Further analysis by the STRING database identified only 22 and 11 proteins from the respective group. Differential expressed analysis of similar proteins from these two groups revealed ACTN4 and ACTN1 as proteins involved in both SHED and DPSC. In addition, three (PSMD11/RPN11, PLS3, and CLIC1) and one (SYNCRIP) protein were differentially expressed specifically for SHED and DPSC, respectively.

    CONCLUSION: Proteome differential expression showed that ascorbic acid alone could induce osteoblastrelated proteins in SHED and DPSC and generate specific differentially expressed protein markers.

    Matched MeSH terms: Tooth, Deciduous*
  2. Evaluation of interfacial adaptation and penetration of bioceramic-based sealers in oval root canals: A confocal laser scanning microscope study
    Chew ST, Eshak Z, Al-Haddad A
    Microsc Res Tech, 2023 Jul;86(7):754-761.
    PMID: 37078493 DOI: 10.1002/jemt.24323
    To assess the interfacial adaptation and penetration depth of three different bioceramic-based sealers (CeraSeal, EndoSeal MTA, Nishika Canal Sealer BG) compared to an epoxy resin-based sealer (AH Plus) in oval root canals. Fourty extracted single-rooted mandibular premolar with oval canal were prepared and randomly allocated according to the obturation into; CeraSeal, EndoSeal MTA, Nishika Canal Sealer BG and AH Plus. The roots were sectioned at 3, 6 and 9 mm from the apex. The sealer adaptation and the penetration depth were evaluated under confocal laser scanning microscope. One-way ANOVA and Repeated measure ANOVA were used to statistically analyze the data. Nishika Canal Sealer BG showed significantly higher sealer adaptation than EndoSeal MTA (P 
    Matched MeSH terms: Tooth Root/anatomy & histology
  3. Impact of calcium hydroxide and 2-hydroxyisocaproic acid on the microhardness of root dentine: an in vitro study
    Niranjan NT, Dastidar PG, Penukonda R, Lin GSS, Babannavar R, Jaysheel A, et al.
    Odontology, 2024 Jul;112(3):711-717.
    PMID: 38087010 DOI: 10.1007/s10266-023-00874-1
    To evaluate and compare the effect of calcium hydroxide [Ca(OH)2] and 2-hydroxyisocaproic acid (HICA) on the microhardness of root dentine. Fifty-one matured maxillary central incisors with straight root and type I canal configuration were decoronated to a standardized length of 16 mm. The root canals were cleaned and shaped using rotary instruments up to size F5. The tooth samples were then randomly assigned into three groups (n = 17) based on the intracanal medicament placed. Group A: control group with no intracanal medicament, Group B: root canals placed with Ca(OH)2, and Group C: root canals placed with HICA. After 1 week, the intracanal medicaments placed within the root canals were removed and the canals were dried. Subsequently, the specimens were split longitudinally into two halves and subjected to the Vickers microhardness test with indentations made at the coronal, middle, and apical-third root regions. The data were analyzed using one-way ANOVA and Tukey's post hoc tests. The control group showed significantly highest microhardness value (P 
    Matched MeSH terms: Tooth Root/drug effects
  4. Protective effect of ellagic acid on healing alveolar bone after tooth extraction in rat--a histological and immunohistochemical study
    Al-Obaidi MM, Al-Bayaty FH, Al Batran R, Hassandarvish P, Rouhollahi E
    Arch Oral Biol, 2014 Sep;59(9):987-99.
    PMID: 24952163 DOI: 10.1016/j.archoralbio.2014.06.001
    This study has attempted to evaluate the effects of ellagic acid (EA) on alveolar bone healing after tooth extraction in rats.
    Matched MeSH terms: Tooth Extraction*; Tooth Socket/drug effects*
  5. Fulltext Minimal guided bone regeneration procedure for immediate implant placement in the esthetic zone
    Kumar NS, Sowmya N, Mehta DS, Kumar PS
    Dent Res J (Isfahan), 2013 Jan;10(1):98-102.
    PMID: 23878571 DOI: 10.4103/1735-3327.111808
    The anterior maxilla presents a challenging milieu interior for ideal placement of implants because of the compromised bone quality. With the advent of intraoral bone harvesting and augmentation techniques, immediate implant placement into fresh extraction sockets have become more predictable. Immediate implant placement has numerous advantages compared to the delayed procedure including superior esthetic and functional outcomes, maintenance of soft and hard tissue integrity and increased patient compliance. This case report exhibits immediate implant placement in the maxillary esthetic zone by combining a minimal invasive autogenous block bone graft harvest technique for ensuring successful osseointegration of the implant at the extraction site.
    Matched MeSH terms: Dental Implants, Single-Tooth
  6. Fulltext Imaging of Osteo-odontokeratoprosthesis(OOKP) Using Multidetector Computed Tomography: A UKMMC Experience
    Abu Bakar N, Lee CL
    Med J Malaysia, 2013;68(1):73-5.
    PMID: 23466774
    Osteo-odontokeratoprosthesis (OOKP) surgery is a technique used to replace damaged cornea in blind patients for whom cadaveric transplantation is not feasible. OOKP surgery is a complex procedure requiring lifetime follow-up. The preservation of the osteo-odontolamina is the vital feature in maintaining the stability of the OOKP. Early detection of lamina resorption enables early prophylactic measures to be taken and prevent resorption-related complications. This case illustrates the radiological findings of the first OOKP surgery in Malaysia and the role of multidetector computed tomography (MDCT) in postoperative management of OOKP surgery.
    Matched MeSH terms: Tooth Root
  7. Can stature be estimated from tooth crown dimensions? A study in a sample of South-East Asians
    Hossain MZ, Munawar KM, Rahim ZH, Bakri MM
    Arch Oral Biol, 2016 Apr;64:85-91.
    PMID: 26803673 DOI: 10.1016/j.archoralbio.2016.01.001
    Stature estimation is an important step during medico-legal and forensic examination. Difficulty arises when highly decomposed and mutilated dead bodies with fragmentary remains are brought for forensic identification like in mass disaster or airplane crash. The body remains could be just a jaw with some teeth. The objective of this study was to explore if the stature of an individual can be determined from the tooth crown dimensions.
    Matched MeSH terms: Tooth
  8. Fulltext Aesthetic Management of Fluoresced Teeth with Ceramic Veneers and Direct Composite Bonding - An Overview and A Case Presentation
    Jhajharia K, Shah HH, Paliwal A, Parikh V, Patel S
    J Clin Diagn Res, 2015 Jun;9(6):ZD28-30.
    PMID: 26266231 DOI: 10.7860/JCDR/2015/12542.6108
    Tooth discolouration is a common problem and affects people of all ages. Apart from the conventional treatment modalities for the same, newer options are available today with better techniques and materials. The present case report describes a 17-year-old girl who had stained and pitted teeth, attributable to dental fluorosis and she desired aesthetic treatment for the same. The pros and cons of all treatment options were carefully weighed and a multistep treatment process involving ceramic veneers and direct bonding were planned. The execution of the planned treatment yielded a good aesthetic and functional outcome.
    Matched MeSH terms: Tooth Discoloration
  9. Fulltext Endodontic Management of a Mandibular First Molar with Unusual Canal Morphology
    Hashem AAR, Ahmed HMA
    Eur Endod J, 2017;2(1):1-4.
    PMID: 33403327 DOI: 10.5152/eej.2017.17042
    A comprehensive knowledge and understanding of root canal anatomical variations are essential for successful root canal treatment. Mandibular molar teeth show considerable variations in their external and internal radicular morphology that require special attention from dental practitioners to provide the best clinical outcomes to the patients. This report aims to present root canal treatment of a mandibular first molar that has six separate root canals (three root canals in the mesial roots and three in the distal roots [236 M3 D3]). This report points out the importance of proper exploration for identifying additional canals in mandibular molars.
    Matched MeSH terms: Tooth Root
  10. Fulltext Influence of light and laser activation of tooth bleaching systems on enamel microhardness and surface roughness
    Yusof EM, Abdullah SA, Mohamed NH
    J Conserv Dent, 2021 02 10;23(5):473-478.
    PMID: 33911356 DOI: 10.4103/JCD.JCD_509_20
    Objective: The objective of this study was to compare the effects of light and laser activation of in-office tooth bleaching systems on enamel microhardness and surface roughness.

    Materials and Methods: Twenty-five enamel slabs were divided into three treatment groups: light-activated bleaching, laser-activated bleaching, and control. The baseline data were recorded for enamel microhardness (Vickers microhardness [VMH]) and surface roughness (Roughness average, Ra). The specimens were cured for 10 min upon hydrogen peroxide application for the light-activated bleaching group and activated with a laser source, 8 cycles, 10 s per cycle for the laser-activated group. The changes in VMH and Ra at days 1, 7, and 28 were evaluated. Kruskal-Wallis, Friedman, Wilcoxon, and Mann-Whitney tests were used to analyze both VMH and Ra between the treatment groups at different time intervals.

    Results: There were a significant reduction in VMH values and significant differences between days 1, 7, and 28 against the baseline in the light-activated bleaching group (P = 0.001). The Ra values revealed significant differences in both light- (P = 0.001) and laser-activated (P = 0.033) groups.

    Conclusion: Light activation of a bleaching agent caused a reduction in enamel microhardness and an increase in surface roughness when compared to laser activation.

    Matched MeSH terms: Tooth Bleaching
  11. Morphological patterns of the palatal rugae: A review
    Chong JA, Mohamed AMFS, Pau A
    J Oral Biosci, 2020 09;62(3):249-259.
    PMID: 32619633 DOI: 10.1016/j.job.2020.06.003
    BACKGROUND: Palatal rugae are asymmetric ridges of connective tissue located behind the incisive papilla over the anterior hard palate. They serve as stable superimposition landmarks to assess tooth movement in orthodontics and as identification aids in forensic odontology. However, the stability of palatal rugae remains controversial. This review aimed to describe the genetic, growth, and environmental factors that may influence the palatal rugae patterns. A broad search of PubMed and ScienceDirect databases was conducted. A total of 193 articles were identified, of which 73 met the selection criteria. Data were extracted into a table that presented the details of the study, sample description, and changes in the palatal rugae patterns.

    HIGHLIGHT: There were conflicting results regarding sexual dimorphism and population characterization of the palatal rugae patterns. All rugae showed positional changes, increased lengths, and lower numbers, but no significant shape changes with growth. The lengths, numbers, and positions of the rugae were affected by orthodontic treatment, especially their lateral points, but their individual characteristics did not change.

    CONCLUSION: The diversity in rugae patterns and their potential for sex discrimination among different populations showed differing results due to individual variations and the complex influence of genetic, growth, and environmental factors on their morphology.

    Matched MeSH terms: Tooth Movement
  12. Fulltext Dental Implant Tissue Interface - An Appraisal
    Taiyeb Ali, T.B.
    Ann Dent, 1997;4(1):-.
    MyJurnal
    Endoseous Implant insertion for the replacement of missing teeth is the state of the art at present times. An understanding of the biology of the perimplant tissues is imperative for the overall success in the dental rehabilitation of a patient with fixture supported prosthesis. The dental implant tissue interface comprises bone, both cortical and cancellous bone; supracrestal connective tissue and the epithelial attachment. A comprehensive review of the response of bone during the postoperative or healing phase, the loading or remodelling phase and during the steady phase is described.
    Matched MeSH terms: Tooth Loss
  13. Fulltext Margin width, internal line angle and labial emergence profiles of maxillary metalloceramic
    Yahya, N.A., Youngson, C.C.
    Ann Dent, 2007;14(1):7-13.
    MyJurnal
    The purpose of this study were to compare the emergence profiles of crowns with their contralateral tooth, in vitro, and to determine if there is any association between the design of tooth preparations and the resultant emergence profile. 50 working models used for single crown construction were examined. Measurements of the faciolingual width of the crowns and contralateral teeth were taken using digital calipers. Internal line angles and the margin width of dies and the emergence profile of the corresponding crowns were measured from longitudinally sectioned polyvinylsiloxane indices mounted on a flat-bed scanner using image analysis software. Using Students t tests, no statistically significant differences (p>0.05) were found for shoulder width (mean 0.94 ± 0.23mm), internal line angle (mean 105.83 ± 13.57°) or emergence profiles (28.56 ± 12.95°) in the different (anterior, premolar or molar) preparations or crowns. The mean emergence profiles for all crowns was statistically significantly greater (p
    Matched MeSH terms: Tooth Preparation
  14. Fulltext Technique to repair iatrogenically-damaged roots during post canal preparation using resin composite and optic fibre posts
    Lui, J.L.
    Ann Dent, 2007;14(1):14-18.
    MyJurnal
    During post crown restoration, the preparation of the post canal can be fraught with difficulties resulting in widening, gouging and transportation of the post canal; sometimes with near root perforation. A technique is described to repair such iatrogenically damaged internal root canal walls using reinforcing resin composite and optic glass fibre posts. The root dentine, resin composite and glass fibres, having similar moduli of elasticity, will result in a repaired root with a ‘monolithic’ structure and possessing numerous desirable characteristics. This repair technique can easily be carried out in one sitting at the chairside thereby allowing the continued serviceability of the iatrogenically compromised root-filled tooth.
    Matched MeSH terms: Tooth Root
  15. Fulltext Posterior teeth mesialization with mini-implants in an oligodontia patient
    Wey, M.C., Wu, C.L., Wong, W.K., Zamri, R., Hagg, U.
    Malaysian Dental Journal, 2008;29(2):113-118.
    MyJurnal
    A case report of a 16 year old male oligodontia patient who presented with a Class I malocclusion on a skeletal I base. He had multiple missing teeth of upper lateral incisors and all premolars except for lower right first premolar. Treatment involved fixed appliance with the aid of mini-implants to mesialize posterior teeth in order to reduce the number of prosthodontic replacement of the remaining missing teeth planned for the future. The application of the mini-implants in the sequence of treatment is presented
    Matched MeSH terms: Tooth Loss
  16. Capital- and consumption-led growth: case study on Malaysia, Singapore, Japan, and Zimbabwe
    Mohd Azlan Abdul Majid, Mariam Setapa, Noorita Mohammad
    CREAM : Current Research in Malaysia (Penyelidikan Terkini di Malaysia), 2012;1(1):151-187.
    MyJurnal
    Tujuan kertas kerja ini adalah untuk mengetahui hubungan, kesan ekonomi semasa dan faktor pencemaran terhadap modal, perbelanjaan terhadap pertumbuhan ekonomi terutamanya kepada Malaysia dan dibandingkan dengan negara seperti Jepun, Singapura dan Zimbabwe. Persoalan utama adalah sama ada modal dan perbelanjaan dapat berterusan menyumbangkan kepada pertumbuhan ekonomi ataupun tidak. Untuk mengkaji perhubungan, kami gunakan Test Unit Root (TUR); Augmented Dickey-Fuller Method (ADF), Phillip-Perron Test (PP) dan Kwiatkowski-Phillip-Schmidt-Shin (KPSS), Test Johansen Cointegration (TJC), diikuti Vector Error Correction Model (VECM) dan akhir sekali Test Granger Causality (TGC). Tujuan pengujian ini adalah untuk mengukur perhubungan, kestabilan dan kesahihan model. Kedua, untuk mengkaji kesan impak ekonomi kami gunakan Impulse Respond dan ujian Variance Decomposition yang menyelidik kesan berapa banyak dan berapa panjang model bertindakbalas kepada kesan Kegawatan Ekonomi Asia pada 1997 dan Kesan Serangan Pengganas di Amerika Syarikat pada September 2011. Ketiga kami juga megukur kesan perbelanjaan isi rumah dan kerajaan terhadap alam persekitaran. Kertas kerja ini mendapati, ia menyokong idea modal penjana pertumbuhan tetapi natijah perbelanjaan penjana pertumbuhan adalah berbeda mengikut tahap pertumbuhan. Di mana Malaysia dan Singapura menyokong sepenuhnya tetapi Jepun dan Zimbabwe hanya menyokong separa sahaja. Apabila kami mengukur impak kesan ekonomi pula, di dapati pada negara Zimbabwe tiada kesan antara krisis pada tahun 1997 ataupun pada 2001. Tetapi impak pada negara seperti Jepun, Malaysia dan Singapura pula berhadapan dalam posisi tidak baik pada krisis tahun 1997 tetapi keadaan yang baik pula pada krisis tahun 2001. Akhir sekali kami juga bangunkan theori pencemaran dimana untuk negara Zimbabwe ke semua pembolehubah seperti Perbelanjaan isi rumah (HC), Perbelanjaan Kerajaan (GC) dan Modal Tetap Kasar (GFC) tidak mempengaruhi pencemaran iaitu Karbon Dioksida (CO2). Tetapi natijah untuk negara Malaysia dan Singapura pula hanya HC mencipta CO2, tidak untuk GC dan GFC. Dan pengakhiran sekali Negara Jepun pula semua pembolehubah seperti GC,HC dan GFC mencipta pencemaran. Kesimpulannya krisis yang berlaku pada negara Amerika Syarikat pada tahun 2001 memberi kesan terus pada Negara Amerika tetapi tidak pada negara seperti Malaysia, Jepun dan Singapura, walhal negara-negara ini menadapat lambakan di dalam pasaran modal akibat perubahan ketidaktentuan dalam ekonomi Amerika seterusnya meningkatkan secara langsung Keluaran Dalam Negara Kasar (GDP). Walaubagaimanapun negara Zimbabwe tidak mempunyai kesan langsung sama ada sebelum atupun selepas masalah krisis ekonomi ini. Apabila kertas kerja ini mengkaji daripada sudut pembangunan lestari didapati Negara Zimbabwe seperti HC dan GC tidaklah mencemar seperti negara Malaysia dan Singapura yang menunjukkan HC punca pencemaran dan bukannya GC yang mungkin disebabkan skala ekonominya yang lebih kecil. Untuk negara Jepun pula disebabkan negara ini mempunyai skala ekonomi yang lebih besar HC dan GC adalah agen kepada pencemaran. Implikasinya model ini sepatutnya diambil kira dalam pembuat keputusan terutamanya untuk meninkatkan pertumbuhan ekonomi.
    Matched MeSH terms: Tooth Root
  17. Fulltext Direct veneer restoration using a nano ceramic composite material: a clinical report
    Yahya, N.A., Lim, K.H.D.
    Ann Dent, 2008;15(2):89-93.
    MyJurnal
    Direct composite veneers can be used to mask tooth discolorations and/or to correct unaesthetic tooth forms and/or positions. However, these type of restorations are often regarded as one of the most challenging in aesthetic dentistry presumably due to the extent of natural tooth structure that must be recreated. This paper discusses easy application techniques and tips for Ceram.X Duo™, a nano ceramic composite restorative material. Its natural shading system allows the restoration of tooth with both dentine and enamel shade and transforms it into a final direct veneer restoration that mimics a natural tooth.
    Matched MeSH terms: Tooth Discoloration
  18. Fulltext Endodontic treatment of a maxillary central incisor with arrested root development: a case report
    Annuar, W.A., Rahman, R.A., Bahadun, J.
    Ann Dent, 2008;15(2):82-88.
    MyJurnal
    Arrested root development of permanent te~th can occur due to local factors such as infection and trauma or general factors such as radiation and odontodysplasia. This case report presents a 11 tooth with arrested root development requiring endodontic treatment. Following obturation with MTA, a minor surgical procedure was performed to remove periapical pathologic tissue. The tooth had remained asymptomatic at the 6-month review and the case will be followed-up for at least 2 years to ensure complete healing.
    Matched MeSH terms: Tooth Root
  19. Fulltext Improving aesthetic of a cast cobalt chrome partial denture with custom made porcelain tooth: a case report
    Adam Husein, Huwaina Abd. Ghani, Fazal Reza
    Archives of Orofacial Sciences, 2012;7(2):1-4.
    MyJurnal
    Replacing a single missing anterior tooth can be a challenge. Many factors need to be considered when choosing the appropriate treatment. Several treatment options are well established. This case report is to present the use of a cast cobalt chrome partial denture with custom made porcelain tooth to improve aesthetic. The overall shade of the artificial tooth were nicely matched with the adjacent teeth and definite enamel translucency could be achieved which would not be possible with acrylic or even with readymade porcelain tooth.
    Matched MeSH terms: Tooth, Artificial
  20. Fulltext Management of a maxillary first molar tooth with unusual mesiobuccal root anatomy
    Hany Mohamed Aly Ahmed, Deepti Saini
    Archives of Orofacial Sciences, 2012;7(2):101-106.
    MyJurnal
    Sufficient knowledge on the root and root canal anatomy is essential for practicing root canal treatment. The mesiobuccal roots of maxillary molar teeth present an endodontic challenge due to their wide variability and complexity of their internal morphological landmarks. A review on the literature indicates that the prevalence of a third mesiobuccal root canal in the mesiobuccal root of maxillary molar teeth may reach 9%, and the root canal configuration usually is type XV (3-2). These reported data reveal the importance of absolute awareness for this anatomical aberration that requires special attention from dental practitioners while commencing root canal treatment in maxillary molar teeth. Hence, this article aims to report and describe the management of a maxillary first molar tooth with three mesiobuccal root canals, but with an unusual configuration.
    Matched MeSH terms: Tooth Root
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