MyMedR

Depth, diameter, and the sub millimetric distinctions

Suresh V, Magoon R, Jose J

Am J Emerg Med, 2024 Oct;84:170-171.

PMID: 39138056 DOI: 10.1016/j.ajem.2024.08.003

Matched MeSH terms: Humans

Salivary biomarkers: Effective diagnostic tool for oral leukoplakia and oral squamous cell carcinoma

Liew YX, Kadir K, Phan CW, Leong KH, Kallarakkal TG, Tilakaratne WM

Oral Dis, 2024 Sep;30(6):3591-3599.

PMID: 38098264 DOI: 10.1111/odi.14835

OBJECTIVE: To identify potential salivary biomarkers for the diagnosis and monitoring of disease progression in oral squamous cell carcinoma and oral leukoplakia.

MATERIALS AND METHODS: An advance search from PubMed and Hindawi was performed with keywords; oral leukoplakia/oral squamous cell carcinoma, salivary biomarker and diagnosis/prognosis. An additional search of articles was done through a manual search from the Google Scholar database.

RESULTS: Twenty studies involving salivary biomarkers as diagnostic tools for oral squamous cell carcinoma and/or oral leukoplakia were identified. A narrative review was carried out.

CONCLUSION: Single or multiple salivary biomarkers reported by most studies have shown great potential as diagnostic tools for oral squamous cell carcinoma and oral leukoplakia. However, the validation of sensitivity and specificity should be carried out to ensure the accuracy of the biomarkers. Furthermore, a standardised method for saliva collection should be established to prevent variability in the expression of biomarkers.

Matched MeSH terms: Humans

Fulltext The Reliability and Validity of the Malay Parent-Report Version of the Strengths and Difficulties Questionnaire

Idris IB, Barlow J, Dolan A, Surat S

Malays J Med Sci, 2021 Feb;28(1):125.

PMID: 30914900 MyJurnal DOI: 10.21315/mjms2021.28.1.18

[This retracts the article DOI: 10.21315/mjms2019.26.1.12.].

Matched MeSH terms: Humans

Detection of SARS-CoV-2 in Environment: Current Surveillance and Effective Data Management of COVID-19

Nadzirah S, Mohamad Zin N, Khalid A, Abu Bakar NF, Kamarudin SS, Zulfakar SS, et al.

Crit Rev Anal Chem, 2024;54(8):3083-3094.

PMID: 37358486 DOI: 10.1080/10408347.2023.2224433

Since diagnostic laboratories handle large COVID-19 samples, researchers have established laboratory-based assays and developed biosensor prototypes. Both share the same purpose; to ascertain the occurrence of air and surface contaminations by the SARS-CoV-2 virus. However, the biosensors further utilize internet-of-things (IoT) technology to monitor COVID-19 virus contamination, specifically in the diagnostic laboratory setting. The IoT-capable biosensors have great potential to monitor for possible virus contamination. Numerous studies have been done on COVID-19 virus air and surface contamination in the hospital setting. Through reviews, there are abundant reports on the viral transmission of SARS-CoV-2 through droplet infections, person-to-person close contact and fecal-oral transmission. However, studies on environmental conditions need to be better reported. Therefore, this review covers the detection of SARS-CoV-2 in airborne and wastewater samples using biosensors with comprehensive studies in methods and techniques of sampling and sensing (2020 until 2023). Furthermore, the review exposes sensing cases in public health settings. Then, the integration of data management together with biosensors is well explained. Last, the review ended with challenges to having a practical COVID-19 biosensor applied for environmental surveillance samples.

Matched MeSH terms: Humans

Accelerated biological brain aging in major depressive disorder

How EH, Chin SM, Teo CH, Parhar IS, Soga T

Rev Neurosci, 2024 Dec 17;35(8):959-968.

PMID: 39002110 DOI: 10.1515/revneuro-2024-0025

Major depressive disorder (MDD) patients commonly encounter multiple types of functional disabilities, such as social, physical, and role functioning. MDD is related to an accreted risk of brain atrophy, aging-associated brain diseases, and mortality. Based on recently available studies, there are correlations between notable biological brain aging and MDD in adulthood. Despite several clinical and epidemiological studies that associate MDD with aging phenotypes, the underlying mechanisms in the brain remain unknown. The key areas in the study of biological brain aging in MDD are structural brain aging, impairment in functional connectivity, and the impact on cognitive function and age-related disorders. Various measurements have been used to determine the severity of brain aging, such as the brain age gap estimate (BrainAGE) or brain-predicted age difference (BrainPAD). This review summarized the current results of brain imaging data on the similarities between the manifestation of brain structural changes and the age-associated processes in MDD. This review also provided recent evidence of BrainPAD or BrainAGE scores in MDD, brain structural abnormalities, and functional connectivity, which are commonly observed between MDD and age-associated processes. It serves as a basis of current reference for future research on the potential areas of investigation for diagnostic, preventive, and potentially therapeutic purposes for brain aging in MDD.

Matched MeSH terms: Humans

Fulltext Stem cell transplantation in Malaysia and future directions

Fadilah SA, Leong CF, Cheong SK

Med J Malaysia, 2008 Oct;63(4):279-80.

PMID: 19385484 MyJurnal

Matched MeSH terms: Humans

Fulltext The arthritis and musculoskeletal quality improvement program (amquip): a breakthrough series methodology project

Mastura I

Malays Fam Physician, 2008;3(2):113-6.

PMID: 25606133 MyJurnal

The Australian government had funded the National Primary Care Collaborative (NPCC) program with funding of $14.6 million over three years. One of the pilots project was the Arthritis and Musculoskeletal Quality Improvement Program (AMQuIP).The study aims to optimize general practitioners (GPs) management of patients with osteoarthritis (OA) of the hip and knee by identifying gaps between their current practice and best practice. The Breakthrough Series Collaborative methodology with several Plan-Do-Study-Act (PDSA) cycles was employed. Participants comprises of 12 GPs/practices from two Victorian Divisions of general Practice (one rural, one metropolitan) with 10 patients per GP/practice. GPs/practices attended an orientation and three learning workshops and a videoconference. GPs/practices completed PDSA cycles between workshop and reported results at workshops. GPs/practices reported use of guidelines, change in patient management and change in practice management/systems. All recruited patients completed the SF-12v2 Health Survey and WOMAC OA Index Questionnaire twice. Follow up activities including focus groups and face-to-face interviews were held six months after the final workshop. All GPs/practices used the guidelines/key messages, introduced "new" management strategies to patients, and made positive changes to their practice management/systems. Patient reported positive changes and outcomes. By using a structured methodology and evidence-based guidelines/key messages; GPs can introduce new patient management strategies, and by identifying gaps in practice management systems, positive changes can be achieved.

Matched MeSH terms: Humans

Cardiac services in Sarawak, Malaysia

Sim KH, Yip Fong AY

Am Heart Hosp J, 2007;5(2):100-2.

PMID: 17478976

Matched MeSH terms: Humans

Fulltext Dystrophic epidermolysis bullosa pruriginosa: the first report of a family in malaysia

Tang MM, Leong KF, Cristina H, Bruckner-Tuderman L

Med J Malaysia, 2013;68(1):81-5.

PMID: 23466777 MyJurnal

Matched MeSH terms: Humans

Family practice in Malaysia

Fam Pract, 1984 Dec;1(4):197-8.

PMID: 6530083 DOI: 10.1093/fampra/1.4.197

Matched MeSH terms: Humans

Fulltext Intensive care units in Malaysia

Delilkan AE

Med J Malaysia, 1989 Jun;44(2):90-1.

PMID: 2626129

Matched MeSH terms: Humans

Fulltext Quality assurance in health care

Pathmanathan I

Med J Malaysia, 1986 Dec;41(4):287-91.

PMID: 3670149

Matched MeSH terms: Humans

Neurosurgery in developing countries

Rapport RL

Surg Neurol, 1984 Jan;21(1):99-100.

PMID: 6689818

Matched MeSH terms: Humans

Drug addiction

Sandosham AA

Med J Malaysia, 1976 Jun;30(4):249.

PMID: 979723

Matched MeSH terms: Humans

A review on thalassemia profile in Malaysia and the challenges of its prevention and control programme

Buang SN, Diana R, Jaafar S, Muhammad DI, Daud MSM, Jamaluddin J, et al.

Malaysian Journal of Public Health Medicine, 2017;17(3):15-26.

This review aims to profile the disease of thalassemia in Malaysia and to identify the challenges that have kept Malaysia from effectively reducing the birth rate of thalassemia patients. The success of thalassemia prevention programs in some countries have shown that more than 90% of the reduction of cases were achieved by using retrospective screening method (prenatal, premarital, retrospective counselling). However, in Malaysia any impact of the prevention program is yet to be visible, and a reduction in new births of thalassemia patients remains to be seen. The number of patients in the national thalassemia registry (www.mytalasemia.net.my) is increasing over the years from 3588 in 2008 to 4990 in 2010 and to 6624 in 2015. The provision of quality care and disease management imposes a huge economic burden on national health resources, which is why an effective prevention program is urgently needed. For Malaysia to reduce the burden of new thalassemia cases, it is vital to address gaps and limitations of the existing preventive strategies. The screening program has to be integrated into existing primary healthcare settings, promoted to every party including the higher ministry bodies and designed to adapt to the highly diverse local religious and cultural backgrounds. Through continuous support by the government, health care providers and the general public, there is hope that prevention and control of this disease may be achieved in the future.

Matched MeSH terms: Humans

Fulltext On dypnoea, its nature, significance and treatment

Lim BK

Journal of the Straits Medical Association, 1894;5:142-52.

Matched MeSH terms: Humans

Cholera necropsies

Catto J

Journal of the Malaya Branch of the British Medical Association, 1903.

Matched MeSH terms: Humans

Notes on the radical cure of hernia

Dick W

Journal of the Malaya Branch of the British Medical Association, 1903.