MyMedR

Fulltext Utilisation of ophthalmic services by foreign nationals in Johor: a review of 452 patients

Hooi SH, Hooi ST

Med J Malaysia, 2003 Oct;58(4):579-86.

PMID: 15190634

Between 1st January 1999 and 31st December 2000, 452 foreign nationals were treated at the Department of Ophthalmology, Hospital Sultanah Aminah, Johor Bahru. Eighty-five percent were male. The peak age range was from 21 to 30 years old. The patients were predominantly Indonesians (61%). A history of trauma was present in 63% of patients. Eight percent of eyes had severe visual impairment. Six patients (1.3%) were blind by WHO standards. Traumatic eye conditions, inflammatory/allergic eye conditions and degenerative eye conditions comprised 66%, 13% and 10% respectively of ocular pathology seen. The commonest ocular findings were corneal foreign body, corneal abrasion and subconjunctival haemorrhage.

Matched MeSH terms: Eye Injuries/epidemiology; Eye Injuries/therapy*

Dengue Maculopathy Associated with Choroidopathy and Pseudohypopyon: A Case Series

Ng CWK, Tai PY, Oli Mohamed S

Ocul Immunol Inflamm, 2018;26(5):666-670.

PMID: 27929712 DOI: 10.1080/09273948.2016.1254804

Matched MeSH terms: Eye Infections, Viral/diagnosis; Eye Infections, Viral/etiology*

Dermoid cyst simulating recurrent dacryocystitis in a toddler

Tengku-Fatishah A, Abdullah B, Sanjeevan N, Nurul-Shuhada AH, Sharifah-Emilia TS, Haron J, et al.

Can J Ophthalmol, 2019 08;54(4):e196-e199.

PMID: 31358169 DOI: 10.1016/j.jcjo.2018.10.006

Matched MeSH terms: Eye Neoplasms/diagnosis*; Eye Neoplasms/surgery

Fulltext Vector and reservoir host of a case of human Brugia pahangi infection in Selangor, peninsular Malaysia

Muslim A, Fong MY, Mahmud R, Sivanandam S

Trop Biomed, 2013 Dec;30(4):727-30.

PMID: 24522144 MyJurnal

A case of human eye infection caused by Brugia pahangi was reported in 2010 in a semi rural village in Selangor, peninsular Malaysia. Our report here reveals results of investigation on the vector and animal host for the transmission of the infection. We conducted entomological survey and cat blood examination in the vicinity of the patient's home. The mosquito species Armigeres subalbatus was incriminated as the vector, whereas cat served as the reservoir host.

Matched MeSH terms: Eye Infections, Parasitic/diagnosis*; Eye Infections, Parasitic/parasitology

Prevalence and risk factors of ocular trauma in an urban south-east Asian population: the Singapore Malay Eye Study

Loon SC, Tay WT, Saw SM, Wang JJ, Wong TY

Clin Exp Ophthalmol, 2009 May;37(4):362-7.

PMID: 19594562 DOI: 10.1111/j.1442-9071.2009.02035.x

To describe the prevalence and risk factors of ocular trauma in an urban Asian population.

Matched MeSH terms: Eye Injuries/classification; Eye Injuries/ethnology*

Prostaglandin F2-Alpha Eye Drops (Bimatoprost) in Graves' Orbitopathy: A Randomized Controlled Double-Masked Crossover Trial (BIMA Trial)

Draman MS, Morris DS, Evans S, Haridas A, Pell J, Greenwood R, et al.

Thyroid, 2019 04;29(4):563-572.

PMID: 30880626 DOI: 10.1089/thy.2018.0506

BACKGROUND: Previous in vitro experiments have demonstrated that prostaglandin F2-alpha (PF2α) reduced proliferation and adipogenesis in a murine cell line and human orbital fibroblasts derived from subjects with inactive Graves' orbitopathy (GO). The objective of this study was to determine if the PGF2α analogue bimatoprost is effective at reducing proptosis in this population.

METHODS: A randomized controlled double-masked crossover trial was conducted in a single tertiary care academic medical center. Patients with long-standing, inactive GO but persistent proptosis (>20 mm in at least one eye) were recruited. Allowing for a 15% dropout rate, 31 patients (26 females) were randomized in order to identify a treatment effect of 2.0 mm (p = 0.05; power 0.88). Following informed consent, participants were randomized to receive bimatoprost or placebo for three months, after which they underwent a two-month washout before switching to the opposite treatment. The primary outcome was the change in exophthalmometry readings over the two three-month treatment periods.

RESULTS: The mean exophthalmometer at baseline was 23.6 mm (range 20.0-30.5 mm), and the mean age of the patients was 55 years (range 28-74 years). The median duration of GO was 7.6 years (interquartile range 3.6-12.3 years). The majority were still suffering from diplopia (61.3%) with bilateral involvement (61.3%). Using multi-level modeling adjusted for baseline, period, and carry-over, bimatoprost resulted in a -0.17 mm (reduction) exophthalmometry change ([confidence interval -0.67 to +0.32]; p = 0.490). There was a mean change in intraocular pressure of -2.7 mmHg ([confidence interval -4.0 to -1.4]; p = 0.0070). One patient showed periorbital fat atrophy on treatment, which resolved on stopping treatment. Independent analysis of proptosis by photographic images (all subjects) and subgroup analysis on monocular disease (n = 12) did not show any apparent benefit.

CONCLUSIONS: In inactive GO, bimatoprost treatment over a three-month period does not result in an improvement in proptosis.

Matched MeSH terms: Eye/drug effects*; Eye/pathology

Fulltext Chronic endogenous fungal endophthalmitis: diagnostic and treatment challenges: A case report

Abu Talib DN, Yong MH, Nasaruddin RA, Che-Hamzah J, Bastion MC

Medicine (Baltimore), 2021 Apr 09;100(14):e25459.

PMID: 33832156 DOI: 10.1097/MD.0000000000025459

RATIONALE: Endogenous fungal endophthalmitis (EFE) is a sight-threatening complication of systemic fungemia. As the prevalence rises, treatment remains a challenge especially when there is a failure in first-line treatment or drug-resistant fungus. This case report studies a case of chronic EFE, focusing on the diagnostic procedures, treatment options, monitoring parameters and the treatment outcome.

PATIENT CONCERNS: A 64-year-old man with underlying well controlled diabetes mellitus was treated with 2 weeks' course of intravenous antifungal fluconazole for pyelonephritis as his blood culture grew Candida albicans. Concurrently, he complained of 3 months of bilateral painless progressive blurring of vision. At presentation, his visual acuity (VA) was light perception both eyes. Ocular examination revealed non granulomatous inflammation with dense vitritis of both eyes.

DIAGNOSIS: He was diagnosed with EFE but the condition responded poorly with the medications.

INTERVENTIONS: He was treated with intravitreal (IVT) amphotericin B and fluconazole was continued. Vitrectomy was performed and intraoperative findings included bilateral fungal balls in the vitreous and retina with foveal traction in the left eye. Postoperatively, vision acuity was 6/24, N8 right eye and 2/60, N unable for left eye with extensive left macular scar and hole. Vitreous cultures were negative. He received multiple IVT amphotericin B and was started on topical steroid eye drops for persistent panuveitis with systemic fluconazole. Ocular improvement was seen after switching to IVT and topical voriconazole. Despite this, his ocular condition deteriorated and he developed neovascular glaucoma requiring 3 topical antiglaucoma agents. Panretinal photocoagulation was subsequently performed.

OUTCOMES: At 3 months' follow-up, his vision acuity remained at 6/24 for right eye and 2/60 for the left eye. There was no recurrence of inflammation or infection in both eyes.

LESSONS: Voriconazole could serve as a promising broad spectrum tri-azole agent in cases of failure in first-line treatment or drug-resistant fungus.

Matched MeSH terms: Eye Infections, Fungal/diagnosis*; Eye Infections, Fungal/therapy*

A new species of troglobitic crab of the genus Stygothelphusa Ng, 1989, from Sarawak, Malaysia (Crustacea: Decapoda: Brachyura: Gecarcinucidae)

Ng PK, Grinang J

Zootaxa, 2014;3774:90-6.

PMID: 24871408 DOI: 10.11646/zootaxa.3774.1.7

A new species of cave crab, Stygothelphusa antu new species, is described from limestone formations in Temurang, Sarawak, Malaysia. The new species is the most highly adapted to a cavericolous lifestyle among the four known species of Stygothelphusa, having a pale body pigmentation, reduced eyes and elongated pereopods. In contrast, the other three species have normal eyes that almost completely fill the orbits. The new species also differs from its congeners by a number of carapace, pereopod and gonopod characters.

Matched MeSH terms: Eye

Fulltext Full thickness macular hole: Early intervention is an important factor in visual prognosis

Ng HK, Yaakub A, Ong LB

Malays Fam Physician, 2014;9(3):42-8.

PMID: 26425305 MyJurnal

Full thickness macular hole is an eye disease, which can cause permanent visual impairment. Current advancement in vitreoretinal surgery has high success rates in repairing them, leading to a significant visual improvement, especially if patient presents early. In this article, three cases of idiopathic full thickness macular hole with different visual outcomes have been presented. All cases were referred by the primary care practitioners and had undergone macular hole surgery with the same vitreoretinal surgeon. The visual outcome was best in the patient who had the earliest presentation and referral. Early detection and referral of these patients is vital so that early surgical intervention can be carried out to improve their vision.

Matched MeSH terms: Eye Diseases

Fulltext Rhino-orbito-cerebral mucormycosis in an immunocompetent patient: case report and review of literature

Shatriah I, Mohd-Amin N, Tuan-Jaafar TN, Khanna RK, Yunus R, Madhavan M

Middle East Afr J Ophthalmol, 2012 Apr-Jun;19(2):258-61.

PMID: 22623872 DOI: 10.4103/0974-9233.95269

Rhino-orbito-cerebral mucormycosis is a fungal infection that can be fatal especially in immunocompromised patients. It is extremely rare in immunocompetent individuals. We describe here an immunocompetent patient who survived rhino-orbito-cerebral mucormycosis due to Saksenaea vasiformis, and provide a literature review of this rare entity.

Matched MeSH terms: Eye Infections, Fungal/complications; Eye Infections, Fungal/diagnosis*; Eye Infections, Fungal/microbiology

Fulltext Ocular injuries and severe ocular surface diseases in Malaysia

Tan AK, Pall S

Med J Malaysia, 2011 Oct;66(4):284-5.

PMID: 22299542 MyJurnal

Matched MeSH terms: Eye Foreign Bodies/complications*; Eye Injuries/etiology*

Fulltext Awareness and knowledge on eye donation among university students

Bharti MK, Reddy SC, Tajunisah I, Ali NA

Med J Malaysia, 2009 Mar;64(1):41-5.

PMID: 19852320 MyJurnal

Four hundred (400) students studying first year Medicine, Dentistry, Laboratory Technology, Pharmacy, Biomedicine and Bioengineering degree courses in the University of Malaya were assessed on their awareness and knowledge on eye donation using an open ended questionnaire. The majority of the students (344, 86%) in this study were aware about eye donation; the awareness was higher in biomedical (77.1%) and medical students (76.7%) compared to the others (55.9%-70.7%). One hundred and eight students (27%) were willing to donate their eyes. Most of the students (376, 94%) did not know about any eye bank in Malaysia. One hundred and sixty (40%) students were aware that whole eye can be removed from the donor and 101 (25.25%) were aware that the cornea can be removed separately. However, only 121 (30.25%) knew that donated eyes were used for corneal grafting. More than half of the students (231, 57.7%) did not know that the donor eye could be stored before transplantation. The results of this study indicate that there is a need to educate the young adults in our society about corneal transplantation so that they can in turn motivate other members of society and their own family members to become eye donors, thus facilitating the availability of donor corneas for corneal transplantation in Malaysia.

Matched MeSH terms: Eye Banks

Bovine pericardium in treating large corneal perforation secondary to alkali injury: a case report

Khanna RK, Mokhtar E

Indian J Ophthalmol, 2008 8 20;56(5):429-30.

PMID: 18711278

To describe use of a locally processed bovine pericardium (BP) to cover a large central corneal perforation following alkali injury and discuss postoperative outcome. A 27-year-old Malay male patient presented two weeks after alkali splashed in his left eye while working. A clinical diagnosis of left central corneal ulcer with limbal ischemia following alkali injury with secondary infection was made. After failed medical therapy, we performed a Gunderson conjunctival flap under local anesthesia that retracted after one week and resulted in a large central corneal perforation with surrounding stromal thinning. The perforation was covered with a locally processed BP xenograft (Lyolemb) supplied by the National Tissue Bank, University Sains Malaysia. Nine months follow-up showed a well-taken graft without any exposure/dehiscence and minimal inflammation. Amniotic membrane transplantation when used as a patch graft needs an urgent tectonic graft to promote corneal stability in patients with severe corneal thinning. The use of processed BP can be a viable option in treating such cases.

Matched MeSH terms: Eye Burns/chemically induced*; Eye Burns/pathology; Eye Burns/surgery

Fulltext Rhino-orbito-cerebral mucormycosis: a treatment dilemma

Jeevanan J, Gendeh BS, Faridah HA, Vikneswaran T

Med J Malaysia, 2006 Mar;61(1):106-8.

PMID: 16708746 MyJurnal

A case of rhino-orbito-cerebral mucormycosis is presented showing its aggressive nature and progression of disease. The typical clinical features, neuroimaging and histological findings are highlighted in this report. Amphotericin B and surgical debridement remain the mainstay of treatment. However, associated co-morbidities need to be addressed.

Matched MeSH terms: Eye Infections, Fungal/diagnosis*; Eye Infections, Fungal/microbiology; Eye Infections, Fungal/surgery*

Fulltext Stem Cell Therapy for Treatment of Ocular Disorders

Sivan PP, Syed S, Mok PL, Higuchi A, Murugan K, Alarfaj AA, et al.

Stem Cells Int, 2016;2016:8304879.

PMID: 27293447 DOI: 10.1155/2016/8304879

Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow conventional treatments have shifted search to a new form of therapy using stem cells. Stem cell progenitors play a major role in replenishing degenerated cells despite being present in low quantity and quiescence in our body. Unlike other tissues and cells, regeneration of new optic cells responsible for visual function is rarely observed. Understanding the transcription factors and genes responsible for optic cells development will assist scientists in formulating a strategy to activate and direct stem cells renewal and differentiation. We review the processes of human eye development and address the strategies that have been exploited in an effort to regain visual function in the preclinical and clinical state. The update of clinical findings of patients receiving stem cell treatment is also presented.

Matched MeSH terms: Eye

Disseminated nocardiosis with bilateral intraocular involvement in a renal allograft patient

Tan SY, Tan LH, Teo SM, Thiruventhiran T, Kamarulzaman A, Hoh HB

Transplant Proc, 2000 Nov;32(7):1965-6.

PMID: 11120022

Matched MeSH terms: Eye Infections, Fungal/complications; Eye Infections, Fungal/diagnosis*; Eye Infections, Fungal/drug therapy

Human dirofilariasis caused by Dirofilaria (Nochtiella) repens in Sri Lanka

Dissanaike AS, Abeyewickreme W, Wijesundera MD, Weerasooriya MV, Ismail MM

Parassitologia, 1997 Dec;39(4):375-82.

PMID: 9802095

Human dirofilariasis due to Dirofilaria (Nochtiella) repens is a common zoonotic infection in Sri Lanka. Todate 70 cases are on record, and they include 3 expatriates from Russia, England and Korea, who were undoubtedly infected in Sri Lanka. Around 30-60% of dogs are infected with D. repens in various parts of the country and the mosquito vectors are Aedes aegypti, Armigeres subalbatus, Mansonia uniformis and M. annulifera. Unlike in other countries of the old world infection is most common in children under the age of 9 years, the youngest being 4 months old and the scrotum, penis and perianal regions of male children appear to be frequent sites for the worms. Dirofilaria (Dirofilaria) immitis is not present in Sri Lanka though it is present in neighbouring countries like India, and Malaysia.

Matched MeSH terms: Eye Infections, Parasitic/epidemiology; Eye Infections, Parasitic/parasitology; Eye Infections, Parasitic/pathology

Fulltext A comparative assessment of prosthetic outcome on enucleation and evisceration in three different etiological eye defects: A case series

Jamayet NB, Kirangi JK, Husein A, Alam MK

Eur J Dent, 2017 4 25;11(1):130-134.

PMID: 28435380 DOI: 10.4103/1305-7456.202636

Enucleation and evisceration are the most common surgical procedures that are performed to manage tumor, trauma, and infection. Given the consequences of surgical intervention, the conditions of the remaining eye socket may affect future prosthetic rehabilitation. A custom-made ocular prosthesis can be used to help restore the esthetics and functional defects and to improve the quality of life of patients with such conditions. An assessment must be performed on the prosthetic outcome before rehabilitation. The etiology of defect, type of surgery, condition of the remaining socket, and patient's age should all be considered. This report discusses three different etiological eye defects that have undergone enucleation and evisceration and describes the factors that have a significant role in the esthetic and functional outcome of the prosthesis. This report should serve as a helpful aid for maxillofacial prosthodontists to understand the primary objective of rehabilitating each eye defect and to meet patient expectations.

Matched MeSH terms: Eye, Artificial

Fulltext Hemicrania Continua With Scintillating Scotoma: A Rare Presentation

Hussein A, Han Shu T, Chong MF, Cheah CF

Cureus, 2020 Sep 27;12(9):e10680.

PMID: 33133846 DOI: 10.7759/cureus.10680

Headache can be a primary or secondary disorder. The characteristics of headache and its associated features, especially the presence of red flag signs, are important in distinguishing secondary from primary causes. Hemicrania continua is a type of primary headache disorder characterized by a continuous unilateral headache with episodes of exacerbations and association with cranial autonomic symptoms, which include several ocular symptoms. The absolute response to indomethacin remains the hallmark of this disease. We would like to report a rare case of hemicrania continua with scintillating scotoma during exacerbations apart from the typical autonomic features of conjunctival injection, ptosis, eyelid edema, and lacrimation.

Matched MeSH terms: Eye

Fulltext Towards a New Innovation of Smart Bat Hat for Visually Impaired People

Saud, Safaa Najah, Muhammad Irsyad Abdullah, Siti Hadijah Shariff, Ram Singh, Ambrick Singh, Baharudin Hamzah, Nordayati Mat Lehat, et al.

Journal of Management & Science, 2018;16(2):54-66.

MyJurnal

Blindness is an area of inadequate the visual conception because of physiological or even neurological aspects. The partial blindness corresponds to the insufficient integration in the expansion of the optic confidence or perhaps visual center of the eye, and also over-all total blindness is the complete inadequacy of the visual light perception. Within this research, a basic, inexpensive, friendly user, sensible blind assist technique is developed to be integrated with the portability of both blind and even visually impaired people in a particular region. The presented work consists of a wearable apparatus is made up of the head hat to facilitate the blind particular person to get around single-handedly safely and securely in order to keep away from any kind of obstructions that could be experienced, even if mounted and also mobile phone, to avoid virtually any probable accident. The primary function of this product is the Ultrasonic sensing unit which is able to inform the blind people if there exist any specific obstacles or otherwise not around them along with the vibrating motor probably would informs the blind people who which negative are the obstacles located. In addition, by pressing the home or work button this system will straight away link to MIT app inventor and the app will send a signal to Google maps to guide the blind people to its desired location. The implemented system is fast, and easy to use and an innovative affordable solution to blind and visually impaired people in third world countries.

Matched MeSH terms: Eye

Displaying publications 201 - 220 of 438 in total