MyMedR

Milk tolerance among malnourished school children in Malaysia

Chen ST, Domala Z

Asia Pac J Public Health, 1989;3(4):274-7.

PMID: 2638907 DOI: 10.1177/101053958900300405

1,256 malnourished children, aged seven to ten years, were selected for study, 575 from Kuala Langat, 416 from Wilayah Persekutuan and 265 from Ulu Selangor. Ninety-three percent of the children were from low socioeconomic groups with large family size, and most of their parents had only primary or no formal education. During the study period, children in Kuala Langat received daily milk supplementation for five days per week, those in Wilayah Persekutuan for two days per week, while those in Ulu Selangor did not receive any milk supplementation. The study shows that a majority of the malnourished primary school children liked to drink milk and that milk intolerance was not a problem among them.

Matched MeSH terms: Lactose Intolerance/complications; Lactose Intolerance/epidemiology*

Effect of continued feeding of cows' milk on asymptomatic infants with milk protein sensitive enteropathy

Iyngkaran N, Yadav M, Boey CG, Lam KL

Arch Dis Child, 1988 Aug;63(8):911-5.

PMID: 3415326

The clinical response and the histological changes in the mucosa of the small bowel in response to continued feeding with cows' milk protein were assessed over a period of 2-6 weeks in 24 infants who had shown histological changes without immediate clinical symptoms after challenge with a diet containing cows' milk protein. Twenty of the 24 infants (83%) thrived well on cows' milk protein. Jejunal biopsy specimens taken six to eight weeks after the initial biopsy showed histological improvement in all 20 infants compared with biopsy specimens taken soon after the challenge, which had shown mucosal damage. The mucosa had returned to normal in 12, was mildly abnormal in seven, and moderately abnormal in one. Corresponding improvements in the activities of mucosal enzymes were seen. In four of the 24 infants (17%) symptoms developed between three and six weeks. Histological examination of the jejunal biopsy specimens showed that mucosal damage had progressed in two, and remained the same in two; moreover, the disaccharidase activities remained depressed. The present study shows that most infants with enteropathy caused by sensitivity to cows' milk protein but without clinical symptoms develop tolerance to the protein and the mucosa returns to normal despite continued feeding with cows' milk protein.

Matched MeSH terms: Lactose Intolerance/complications; Lactose Intolerance/pathology*

Fulltext Hypolactasia & lactose intolerance among three ethnic groups in Malaysia

Asmawi MZ, Seppo L, Vapaatalo H, Korpela R

Indian J Med Res, 2006 Dec;124(6):697-704.

PMID: 17287558

Prevalence of adult-type hypolactasia is known to vary among different countries and in different ethnic populations in the same country. The present study was undertaken to evaluate the prevalence of hypolactasia and lactose intolerance in three different ethnic populations living in similar environmental conditions in Malaysia. The correlation between different symptoms and lactose intolerance test was also studied.

Matched MeSH terms: Lactose Intolerance/ethnology; Lactose Intolerance/epidemiology*

Fulltext Lactose tolerance and intolerance in Malaysians

Barling PM

International e-Journal of Science, Medicine & Education, 2012;6(10):0-0.

MyJurnal

This review explores the digestibility of lactose by Malaysians, and the value of milk and other milk-derived products as sources of appropriate nutrition for Malaysians. Increased calcium intake through consumption of milk is an effective mechanism for increasing calcium uptake from the diet and thereby minimising the risk of development of osteoporosis in later life. Detailed information about rates of lactose intolerance, and adaptation to dietary lactose and its consequences for Malaysians, will help in the formulation of dietary advice, and improve commerial food manufaturing practice and Government policy
directed to the minimization of rates of osteoporosis, which presents a substantial morbidity risk to elderly female Asians in particular.

Matched MeSH terms: Lactose Intolerance

A rational approach to infant feeding in the management of sugar intolerance associated with infantile enteritis

Chua CP

Med J Malaysia, 1975 Dec;30(2):98-101.

PMID: 1228389

Matched MeSH terms: Lactose Intolerance/complications

Fulltext Lactase deficiency and lactose intolerance in a multiracial Asian population in Malaysia

Goh LH, Mohd Said R, Goh KL

JGH Open, 2018 Dec;2(6):307-310.

PMID: 30619942 DOI: 10.1002/jgh3.12089

Background and Aims: There have been few reports on lactase deficiency (LD) and lactose intolerance (LI) in Malaysia, which has a peculiar mix of three distinct major Asian races-Malay, Chinese, and Indian. The aim of this study was to determine the prevalence of LD and LI in a young multiethnic Malaysian population.

Methods: Lactase activity was measured with a 13CO2 lactose breath test using an infrared spectrometer. Each subject took 25 g of lactose naturally enriched in 13CO2 together with 250 mL of water after an overnight fast. Breath samples were collected at baseline and at 15-min intervals for 180 min. Subjects were asked to report gastrointestinal (GI) symptoms following ingestion of the lactose test meal.

Results: Of the 248 subjects tested, 216 (87.1%) were lactase deficient. We found no significant differences in the presentation of LD between gender and races. LD was found in 87.5% of males and 86.8% of females (P = 0.975) and in different races: Chinese (88.5%) versus Malay (83.1%) (P = 0.399), Indian (90.5%) versus Malay (P = 0.295), and Chinese versus Indian (P = 0.902). LI was diagnosed in only 49 (19.8%) subjects; 35 patients had diarrhea, while the remainder had at least two other GI symptoms after the lactose meal.

Conclusion: The prevalence of LD was high in all three major ethnic groups-Malays, Chinese, and Indians. Ironically, the prevalence of LI was low overall.

Matched MeSH terms: Lactose Intolerance

Atititude of asians to calcium and vitamin d rich foods and supplements: a systematic review

Chin Yi Chan, Norazlina Mohamed, Soelaiman Ima-nirwana, Kok-yong Chin

Sains Malaysiana, 2018;47:1801-1810.

The prevalence of osteoporosis is increasing in Asian countries. Optimum calcium intake and vitamin D level are
important to prevent osteoporosis. The attitude of the society towards calcium food sources and supplements, as well
as sun exposure, influence their bone health practices. This review aimed to summarize the current literature on the
attitude of Asians on calcium and vitamin D rich foods and supplements to understand the barriers among the Asians
in achieving adequate calcium intake and vitamin D level. Studies showed that most Asians have a negative attitude
towards calcium-rich foods, mainly dairy products due to lactose intolerance, aversion to the taste of dairy products or
the absence of motivation. Although they took supplements to fill the gap in their diet, they were not aware of the daily
recommended intake of calcium. Besides, the majority of them have a negative attitude towards sun exposure due to the
fear of getting skin cancer or tanning. As a conclusion, most of Asians are still not aware of the importance of calcium
and vitamin D for their health and their negative attitude must be corrected to prevent the rise of osteoporosis.

Matched MeSH terms: Lactose Intolerance

Fulltext Beneficial Properties of Probiotics

Shi LH, Balakrishnan K, Thiagarajah K, Mohd Ismail NI, Yin OS

Trop Life Sci Res, 2016 Aug;27(2):73-90.

PMID: 27688852 MyJurnal DOI: 10.21315/tlsr2016.27.2.6

Probiotics are live microorganisms that can be found in fermented foods and cultured milk, and are widely used for the preparation of infant food. They are well-known as "health friendly bacteria", which exhibit various health beneficial properties such as prevention of bowel diseases, improving the immune system, for lactose intolerance and intestinal microbial balance, exhibiting antihypercholesterolemic and antihypertensive effects, alleviation of postmenopausal disorders, and reducing traveller's diarrhoea. Recent studies have also been focused on their uses in treating skin and oral diseases. In addition to that, modulation of the gut-brain by probiotics has been suggested as a novel therapeutic solution for anxiety and depression. Thus, this review discusses on the current probiotics-based products in Malaysia, criteria for selection of probiotics, and evidences obtained from past studies on how probiotics have been used in preventing intestinal disorders via improving the immune system, acting as an antihypercholesterolemic factor, improving oral and dermal health, and performing as anti-anxiety and anti-depressive agents.

Matched MeSH terms: Lactose Intolerance

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