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  1. Eravelly J
    Family Practitioner, 1977;2:13-19.
    Matched MeSH terms: Syncope
  2. Sheldon RS
    Clin Auton Res, 2020 04;30(2):101-103.
    PMID: 31925588 DOI: 10.1007/s10286-019-00663-3
    Matched MeSH terms: Syncope*
  3. Siew KSW, Tan MP, Hilmi IN, Loch A
    BMC Cardiovasc Disord, 2019 08 07;19(1):191.
    PMID: 31391000 DOI: 10.1186/s12872-019-1174-4
    BACKGROUND: Swallow or deglutition syncope is an unusual type of neurally-mediated syncope associated with life-threatening bradyarrhythmia and hypotension. It is a difficult condition to diagnose with commonly delayed diagnosis and management. There is lack of review articles that elucidate the basic demographics, clinical characteristics and management of this rare condition. This publication systematically reviews the 101 case reports published since 1793 on swallow syncope.

    CASE PRESENTATION: A 59-year-old man presented with the complaint of recurrent dizziness associated with meals. A 24-h ambulatory ECG recording confirmed an episode of p-wave asystole at the time of food intake. Oesophagogastroduodenoscopy with balloon inflation in the mid to lower oesophagus resulted in a 5.6 s sinus pause. The patient's symptoms resolved completely following insertion of a permanent dual chamber pacemaker.

    CONCLUSIONS: Swallow syncope is extremely rare, but still needs to be considered during diagnostic workup. It is commonly associated with gastro-intestinal disease. Permanent pacemaker implantation is the first line treatment.

    Matched MeSH terms: Syncope/diagnosis; Syncope/etiology*; Syncope/physiopathology; Syncope/therapy
  4. Ramli M, Hassan AS, Rosnani S
    Int J Eat Disord, 2009 Apr;42(3):290-2.
    PMID: 19016482 DOI: 10.1002/eat.20596
    Hypoglycemic attack had been reported as one of the medical complications in anorexia nervosa.
    Matched MeSH terms: Syncope/etiology; Syncope/epidemiology
  5. Tan MP, Ho YY, Chin AV, Saedon N, Abidin IZ, Chee KH, et al.
    Clin Auton Res, 2020 04;30(2):121-128.
    PMID: 31079241 DOI: 10.1007/s10286-019-00610-2
    PURPOSE: To determine the lifetime cumulative incidence of syncope, potential ethnic differences and factors associated with syncope using the Malaysian elders longitudinal research (MELoR) study first wave dataset.

    METHODS: The MELoR study recruited community-dwelling adults aged 55 years and over, selected through stratified random sampling from three parliamentary constituencies. The baseline data collected during the first wave was obtained through face-to-face interviews in participants' homes using computer-assisted questionnaires. During their baseline assessments, participants were asked whether they had ever experienced a blackout in their lifetime and if they had experienced a blackout in the preceding 12 months.

    RESULTS: Information on blackouts and ethnicity were available for 1530 participants. The weight-adjusted lifetime cumulative incidence of syncope for the overall population aged 55 years and above was 27.7%. The estimated lifetime cumulative incidence according to ethnic groups was 34.6% for Malays, 27.8% for Indians and 23.7% for Chinese. The estimated 12-month incidence of syncope was 6.1% overall, equating to 11.7% for Malays, 8.7 % for Indians and 2.3% for Chinese. Both Malay [odds ratio (OR) 1.46; 95% confidence interval (CI) 1.10-1.95 and OR 3.62, 95% CI 1.96-6.68] and Indian (OR 1.34; 95% CI 1.01-1.80 and OR 3.31, 1.78-6.15) ethnicities were independently associated with lifetime and 12-month cumulative incidence of syncope, respectively, together with falls, dizziness and myocardial infarction.

    CONCLUSION: Ethnic differences exist for lifetime cumulative incidence of syncope in community-dwelling individuals aged 55 years and over in an urban area in Southeast Asia. Future studies should now seek to determine potential genetic, cultural and lifestyle differences which may predispose to syncope.

    Matched MeSH terms: Syncope/diagnosis*; Syncope/ethnology*; Syncope/genetics
  6. Koh CS
    Med J Malaysia, 1987 Dec;42(4):269-71.
    PMID: 3454398
    An 84 year old man who presented with Stokes Adams syncope with exertion was found to have complete heart block on walking with reversion to sinus rhythm on recovery. The resting ECG showed evidence of ischemic heart disease with old anteroseptal and old inferior infarction but there was no recent myocardial infarction as shown by normal cardiac enzymes levels. The probable explanation for the mechanism and causation of the transient A-V block is described.
    Matched MeSH terms: Syncope/etiology
  7. Mak WW, Raja Nurazni RA, Mohamed Badrulnizam LB
    Med J Malaysia, 2018 10;73(5):349-350.
    PMID: 30350825 MyJurnal
    Thyroid disease is common and can have various systemic manifestations including cardiac diseases. Hypothyroidism is commonly associated with sinus bradycardia, low QRS complexes, prolonged QT interval and conduction blocks but rarely may cause arrhythmias. We present a patient who presented with presyncope and supraventricular tachycardia with severe hypothyroidism. Patient responded well to thyroxine replacement with biochemical improvement, the disappearance of arrhythmia after restoration of euthyroidism suggests that hypothyroidism might be the cause of supraventricular tachycardia. The aim of this report is to underline the possible aetiological link between supraventricular tachycardia and hypothyroidism, although supraventricular arrhythmias are ordinary features of hyperthyroidism.
    Matched MeSH terms: Syncope
  8. Saedon NI, Zainal-Abidin I, Chee KH, Khor HM, Tan KM, Kamaruzzaman SK, et al.
    Clin Auton Res, 2016 Feb;26(1):41-8.
    PMID: 26695401 DOI: 10.1007/s10286-015-0327-5
    To determine the magnitude of postural blood pressure change, differences in ECG between fallers and non-fallers were measured. Postural blood pressure change is associated with symptoms of dizziness, presyncope, and syncope.
    Matched MeSH terms: Syncope/etiology; Syncope/physiopathology*
  9. Gan SY, Saedon NI, Sukanya S, Fairuz NHA, Sakinah SMN, Fatin NIAH, et al.
    Med J Malaysia, 2017 08;72(4):203-208.
    PMID: 28889130 MyJurnal
    No abstract available.
    Matched MeSH terms: Syncope/diagnosis; Syncope/therapy*
  10. Quek DK, Ong SB
    Singapore Med J, 1990 Apr;31(2):185-8.
    PMID: 2371586
    A 26-year old woman with congenital complete heart block and prolonged QT interval presented for the first time with syncopal attacks associated with torsade de pointes in adulthood. Cardioversion followed by overdrive pacing was needed to finally control the unstable rhythm. During episodes of non-capture, paraoxysms of torsade de pointes leading to ventricular flutter were recorded by a 24-hour ambulatory electrocardiographic monitoring. Beta-blockade and permanent ventricular pacing finally abolished both the syncopal attacks and the torsade phenomena. The prognosis of congenital complete heart block associated with QT prolongation resembles that of the Romano-Ward syndrome. Recognition of this variant would facilitate earlier treatment of this rare but potentially lethal disorder.
    Matched MeSH terms: Syncope/diagnosis; Syncope/etiology*
  11. Tan MP, Chadwick TJ, Kerr SR, Parry SW
    J Am Heart Assoc, 2014 Jun;3(3):e000514.
    PMID: 24947997 DOI: 10.1161/JAHA.113.000514
    Carotid sinus hypersensitivity (CSH) is associated with syncope, unexplained falls, and drop attacks in older people but occurs asymptomatically in 35% of community-dwelling elders. We hypothesized that impaired cerebral autoregulation is associated with the conversion of asymptomatic CSH to symptomatic CSH. We therefore conducted a case-control study evaluating individuals with CSH with and without the symptoms of syncope or unexplained falls, as well as non-CSH controls, to determine whether the blood pressure and heart rate changes associated with CSH are associated with symptoms only when cerebral autoregulation is altered.
    Matched MeSH terms: Syncope/complications; Syncope/physiopathology*
  12. Said Mogutham NN, Abdullah JM, Idris Z, Ghani ARI, Abdul Halim S, Naesarajoo JJJ, et al.
    Malays J Med Sci, 2020 Dec;27(6):89-101.
    PMID: 33447137 DOI: 10.21315/mjms2020.27.6.9
    Background: Dizziness is a common presenting complaint among patients in Malaysia. It is a vague term which could be associated with vertigo, imbalance, ataxia or syncope. In order to deal with this overwhelming complaint, a detailed history-taking is essential in confirming aetiology of disease and this should be followed by a meticulous clinical examination. The purpose of the video manuscript it to provide a step-by-step approach to a dizzy and swaying patient, specially catered for Malaysian medical students and trainees.

    Methods: A series of videos were shot, which involved the eye, ear, vestibular system, cerebellar, proprioceptive sense and gait examination. These videos, conducted in Universiti Sains Malaysia (USM) School of Medical Sciences, will be first in Malaysia and will highlight the proper technique and rapport with patients and essential points of each examination. There will be summary at the end of each examination on how to report findings which is a common weakness among students.

    Conclusion: We hope that students and junior doctors could be apply these methods in their daily assessment of dizzy patients and ultimately, reach an accurate diagnosis.

    Matched MeSH terms: Syncope
  13. Khoo CS
    Perm J, 2018;22:18-081.
    PMID: 30227913 DOI: 10.7812/TPP/18-081
    Matched MeSH terms: Syncope, Vasovagal/diagnosis*
  14. Hasan I, Arshad A, Rahim NA, Soo PY
    Asian J Transfus Sci, 2020 07 24;14(1):28-32.
    PMID: 33162702 DOI: 10.4103/ajts.AJTS_111_17
    CONTEXT: Whole blood donation is generally considered a safe procedure; however, a small percentage of donors could develop vasovagal reactions (VVRs) during or after completion of blood donation.

    AIMS: This study was undertaken to establish the prevalence of VVR among whole blood donors in Hospital Pulau Pinang and to investigate factors that lead to its occurrence.

    SETTINGS AND DESIGN: A cross-sectional study was conducted involving 27,890 whole blood donations in 2016.

    SUBJECTS AND METHODS: For each donation, donor's demographic and blood donation-related information was extracted from the blood bank database.

    STATISTICAL ANALYSIS USED: Qualitative data including age group, sex, race, frequency, and location of donation were analyzed using Chi-square tests, while blood pressure was analyzed using t-test.

    RESULTS: Overall, 425 cases of VVRs were reported, resulting in a VVR rate of 1.5% (one event in every 65 donations). We found a statistically significant association (P < 0.05) between the occurrence of VVRs with the young age group, female gender, Indian race, first-time donor, lower predonation blood pressure, and donation performed in a mobile donation campaign. The most common vasovagal symptoms are lightheadedness (88%), followed by nausea (5.4%), muscle twitching (3.5%), vomiting (1.4%), loss of consciousness <30 s (1.4%), and paresthesia (0.2%).

    CONCLUSIONS: The prevalence of VVRs among whole blood donors in Hospital Pulau Pinang appeared to be low. Our study reaffirms that blood donation is a relatively safe process, and the incidence of VVR can be further reduced by ensuring strict screening procedure before blood donation.

    Matched MeSH terms: Syncope, Vasovagal
  15. Lui, Sze Yee, Noor Zuraini Abu Bakar, Ida Zaliza Zainol Abidin
    MyJurnal
    The clinical diagnosis of snakebite is critical, particularly in Southeast Asia where venomous snakebites are a public health concern. Additionally, cases involving unwitnessed snakebite with no species identification, especially in non-verbal children posed a challenge in the emergency setting. A 2-year-2-month-old boy presented to our emergency department with signs of neurotoxicity. He was restless and mildly bradypnoeic with the respiratory rate of 24 to 28 breaths per minute. He also had bilateral ptosis with absent gag reflex. There were faint fang marks noted over the medial aspect of his left ankle with local swelling and bruises, despite no history of animal bite and no eyewitness. A high index of suspicion of neurotoxic envenomation was prompted and a total of 6 vials of neuro-polyvalent anti-venom were administered in scheduled batches. Progressive clinical recovery was subsequently observed after the first batch of anti-venom administration. The case illustrated the importance of clinical recognition of neurotoxic envenomation in the absence of snake bite history or species identification. Early administration of anti-venom may potentially reverse the neurotoxic effects of systemic envenomation and saves lives.
    Matched MeSH terms: Syncope
  16. Azwan A., Rusli N., Nik Khairol Reza M.Y., Ahmad Syaarani Y., Edimansyah A., Mazalisah M., et al.
    MyJurnal
    Heat stress is considered to be the sum of heat generated in the body (metabolic heat) plus the heat gained from the environment (environmental heat) minus the heat lost from the body to the environment. The consequences of heat stress can caused heat disorder such as heat stroke, heat syncope, heat exhaustion, heat cramps and other heat related diseases. The objective of this study was to compare the pattern of heat stress in each section. A crosssectional study was carried out in two sections (Paintshop A and Bodyshop B) in a selected automotive assembly plant in Selangor to monitor the environmental heat stress. The environmental heat monitoring was done on 89 March 2005. Heat stress monitor (Model: QUESTemp o 34 Thermal Environment Monitor, Quest Technologies, USA) was used to record the pattern of heat exposure in the workplace over a period of eight hours. Heat parameters such as dry temperature, wet temperature, globe temperature and relative humidity were measured. Wet Bulb Globe Temperature index (WBGT) and workload evaluation were used to compare both sections. Heat parameters such as timeweighted average wet bulb globe temperature for indoor setting (TWAWBGT indoor ), dry temperature (DB), natural wet bulb temperature (WB), globe temperature (GB) in Paintshop A were higher than those in Bodyshop B. The relative humidity in Paintshop A was hotdry compared to Bodyshop B which is hotwarm. Paintshop A was considered a hot area compared to Bodyshop B which is normal. Workers in both sections were not faced with heat stress problems because they were worked under acceptable condition according to American Conference of Governmental Industrial Hygienists standard. Both sections in the automotive assembly plant exhibited acceptable working condition for workers in a tropical environment.
    Matched MeSH terms: Syncope
  17. Ooi, Cheng Lee, Nazri Abdul Muthalib
    MyJurnal
    Many factors contribute to the reluctance towards blood donation, but available studies done in Malaysia involving University students does not reflect the knowledge of the public in general. The objective of this study is to determine knowledge, attitude practice towards blood donation among the Sandakan population. A cross-sectional study was employed using an adapted 29-item structured validated questionnaire available in English and Bahasa, consisting of subject’s demography, questions regarding knowledge, attitude, and perception of blood donation. Convenient random sampling was done within the hospital compound, 79 healthy adults consented, and their data were used for the final data analysis, yielding an excellent internal consistency (Cronbach’s α coefficient = 0.816). Out of all, 74.7% of the respondents had a high level of knowledge, and independent t-tests showed that those who were not married, had tertiary education, donated blood in the past, had a statistically significant higher level of knowledge and 96.2% of respondents have a positive attitude. Some donors (40.6%) donated blood for moral satisfaction, and only a quarter (25%) experienced adverse events. Fear of pain, needle, fainting was the highest reason for reluctance in blood donation (36.2% of non-donors), followed by self-perception of being medically unfit to donate (31.9% of non-donors). Even though the sampled population in Sandakan showed an adequate level of knowledge as well as a positive attitude towards blood donation, blood product shortage is still present. This study may contribute by serving as an educational platform for awareness and education to improve the number of blood donors.
    Matched MeSH terms: Syncope
  18. Siti Zulaiha Binti Che Hat
    MyJurnal
    Scimitar syndrome is a rare congenital heart defect occurring in 1 to 3 per 100,000 live births. This is a case of a 26 years old lady presenting with episodic fainting spells since the age of 18 years old. She was initially diagnosed with epilepsy until a referral to our centre found a soft splitting of the second heart sound and multiple premature ventricular complexes on ECG. The computed tomography of the pulmonary artery confirmed the diagnosis if Scim- itar syndrome in the presence of anomalous single right pulmonary vein draining into infra-diaphragmatic systemic venous circulation. A corrective open-heart surgery to re-implant the pulmonary vein was performed with excellent clinical outcomes. Therefore, it is crucial for clinicians to embody high index of suspicion of congenital anomaly even in adults presenting with indefinite clinical symptoms. This report also represents the first published case of adult Scimitar syndrome from Malaysia.

    Matched MeSH terms: Syncope
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