MyMedR

Fulltext Detection of neovascularization in diabetic retinopathy

Hassan SS, Bong DB, Premsenthil M

J Digit Imaging, 2012 Jun;25(3):437-44.

PMID: 21901535 DOI: 10.1007/s10278-011-9418-6

Diabetic retinopathy has become an increasingly important cause of blindness. Nevertheless, vision loss can be prevented from early detection of diabetic retinopathy and monitor with regular examination. Common automatic detection of retinal abnormalities is for microaneurysms, hemorrhages, hard exudates, and cotton wool spot. However, there is a worse case of retinal abnormality, but not much research was done to detect it. It is neovascularization where new blood vessels grow due to extensive lack of oxygen in the retinal capillaries. This paper shows that various combination of techniques such as image normalization, compactness classifier, morphology-based operator, Gaussian filtering, and thresholding techniques were used in developing of neovascularization detection. A function matrix box was added in order to classify the neovascularization from natural blood vessel. A region-based neovascularization classification was attempted as a diagnostic accuracy. The developed method was tested on images from different database sources with varying quality and image resolution. It shows that specificity and sensitivity results were 89.4% and 63.9%, respectively. The proposed approach yield encouraging results for future development.

Occult open globe injury in a patient with corneal foreign body: a case report

Kah TA, Salowi MA, Tagal JM, Thanaraj A, Premsenthil M, Gudom Ia

Cornea, 2009 Dec;28(10):1164-6.

PMID: 19770717 DOI: 10.1097/ICO.0b013e31819aa9d9

To demonstrate the role of ultrasonographic biomicroscopy in diagnosing occult open globe injury.

Fulltext Spontaneous malignant glaucoma in a patient with patent peripheral iridotomy

Premsenthil M, Salowi MA, Siew CM, ak Gudom I, Kah T

BMC Ophthalmol, 2012;12:64.

PMID: 23241197 DOI: 10.1186/1471-2415-12-64

To report a case of spontaneous malignant glaucoma in an Asian female. To propose the term "positive vitreous pressure glaucoma" to reflect the pathophysiology, treatment and prognosis of the condition.

Fulltext The screening of visual impairment among preschool children in an urban population in Malaysia; the Kuching pediatric eye study: a cross sectional study

Premsenthil M, Manju R, Thanaraj A, Rahman SA, Kah TA

BMC Ophthalmol, 2013 Apr 19;13:16.

PMID: 23601160 DOI: 10.1186/1471-2415-13-16

BACKGROUND: To screen for visual impairment in Malaysian preschool children.

METHODS: Visual screening was conducted in 400 preschool children aged 4 to 6 years. The screening involved two basic procedures; the distant visual acuity test using the Sheridan Gardiner chart and the depth perception test using the Langs stereoacuity test. Criteria for referral were a visual acuity of 6/12 or less in the better eye or a fail in the depth perception test.

RESULTS: The prevalence of visual impairment was 5% (95% confidence interval [CI] = 3.3, 7.6). Of the 400 preschool children screened, 20 of them failed the distant visual acuity test or the stereopsis test. Refractive errors were the most common cause of visual impairment (95%, 95% CI = 76.2, 98.8); myopic astigmatism was the commonest type of refractive error (63.2%, 95% CI = 40.8, 80.9).

CONCLUSION: The study is a small but important step in the effort to understand the problem of visual impairment among our preschool children. Our study showed that it is feasible to measure distant visual acuity and stereopsis in this age group.

Displaying all 4 publications