The objective of this study was to examine the mammographic breast density of women with breast cancer detected on voluntary mammographic screening at two selected screening centersin Malaysia.This was a retrospective study of Full-Field Digital Mammography(FFDM) images of150 Malaysian women with biopsy-proven breast cancer. The study population comprised 73 Malays(37.7%), 59 Chinese (39.3%) and 18 Indians (12.0%). The Tabár breast density Patterns(I -V) wereused to evaluate mammographic breast density. Data were analyzed using descriptive statistics. The results were compared with findings from a similar study on a group of 668 women who did not have breast cancer.The results showed that 44.7% of the study populationhad dense breasts (Patterns IV and V), 14.7% had predominantly fatty breasts (Patterns II and III) while 40.7% had Pattern I. The proportion of study populationwith dense breasts decreased with age. In conclusion, the proportion of women with dense breasts decreased with age. Majority of the women with cancer (44.7%) had dense breasts of Tabár Patterns IV and V, which has been associated with increased risk of breast cancer detected by voluntary mammographic screening. The results support the notion that increased breast density is a risk factor of breast cancer.
This paper aims at presenting preliminary results of a survey on physical factors, namely tube
potential (kV), tube current exposure time product (mAs) and compressed breast thickness (CBT)
during voluntary mammography screening using Full-Field Digital Mammography (FFDM) System
in Malaysia. Retrospective data were collected from 1128 FFDM images of 282 women from three
major ethnic groups (Malay, Chinese and Indian) who underwent voluntary screening
mammography at Breast Centre, International Islamic University Malaysia from January to March
2008. Results from the present study were then compared with results from the previous study on
Screen-Film Mammography System (SFM) according to the ethnic group for both Cranio-caudal
(CC) and Mediol-Lateral (MLO) views. We found that the mean kV for CC view for the three ethnic
groups are Malay (28), Chinese (28) and Indian (28), and for MLO view are Malay (29), Chinese
(28) and Indian (29). These values are higher than the kV for SFM which were Malay (26), Chinese
(27) and Indian (26) for CC and Malay (26), Chinese (27) and Indian (26) for CC and MLO views
respectively. The mean mAs for CC and MLO views for FFDM were lower compared to SFM
systems. These values were Malay (104), Chinese (108) and Indian (91) for CC views and Malay
(106), Chinese (105), and Indian (94) for MLO views for the FFDM system. The values for SFM
system are for CC and MLO views were Malay (120), Chinese (106) and Indian (126), and Malay
(166), Chinese (132), Indian (183) respectively. The median CBT for CC and MLO views increased
by 27% and 7% respectively on the FFDM compared to the SFM system. In conclusion, the FFDM
operates with higher kV, lower mAs, and higher CBT when compared with SFM system. Median
CBT on CC and MLO view with FFDM system are 27% and 7% higher respectively compared to
the SFM. We are currently collecting data on mean glandular dose with FFDM systems to assess
how the change in local mammography practice influences this value. This will allow comparison
with related data from other parts of the world.