MyMedR

Displaying all 4 publications

Abstract:

Sort:

Impacts of PM2.5 on respiratory system among traffic policemen

Putri Anis Syahira MJ, Karmegam K, Nur Athirah Diyana MY, Irniza R, Shamsul Bahri MT, Vivien H, et al.

Work, 2020;66(1):25-29.
PMID: 32417810 DOI: 10.3233/WOR-203147

BACKGROUND: Malaysian traffic policemen are constantly exposed to unhealthy air in the outdoor environment, which results in various health problems. This study investigates the relationship of the personal exposure level to PM2.5 and lung functions in traffic policemen in Kuala Lumpur and Johor Bahru.
METHODS: A pulmonary function test using a spirometer was carried out to measure the lung function of the traffic policemen. The personal exposure level to PM2.5 was measured using a pump with a PVC filter and 5.0μm pore size. A questionnaire requesting the background data, such as age, height, and weight, was also used for testing lung function abnormalities.
RESULTS: The PM2.5 personal exposure level was found to be significantly related to lung function (predicted FEV1 and predicted FVC) at p-value

Matched MeSH terms: Air Pollutants, Occupational/adverse effects*
Does GSTP1 polymorphism contribute to genetic damage caused by ageing and occupational exposure?

Eshkoor SA, Ismail P, Rahman SA, Moin S

Arh Hig Rada Toksikol, 2011 Dec;62(4):291-8.
PMID: 22202462 DOI: 10.2478/10004-1254-62-2011-2088

The aim of our study was to see the effects of GSTP1 polymorphism on biomarkers of ageing, including micronuclei (MN), comet tail length, and relative telomere length in automobile repair workers, who are exposed to a broad spectrum of potential mutagens. The analysis was performed on buccal cells collected from occupationally exposed and non-exposed (control) subjects. Samples were analysed using cytogenetic and molecular methods, including restriction fragment length polymorphism (RFLP), MN test, comet assay, and real-time PCR. The results confirmed the DNA damaging effects of substances used in the mechanical workshops, but did not confirm the influence of GSTP1 gene polymorphism on DNA damage. However, further studies on both occupationally exposed and control populations are needed to understand the relationship between GSTP1 polymorphism and genome damage.

Matched MeSH terms: Air Pollutants, Occupational/adverse effects*
Aerosol particle and organic vapor concentrations at industrial work sites in Malaysia

Armstrong RW, Rood MJ, Sani S, Mohamed M, Rashid M, Jab AT, et al.

Asia Pac J Public Health, 2001;13(1):24-9.
PMID: 12109256 DOI: 10.1177/101053950101300106

The objective of this study was to establish baseline data about air pollutants potentially related to nasopharyngeal carcinoma (NPC) in the Federal Territory and Selangor, Malaysia. During 1991-1993, ambient air quality was monitored at 42 work sites representing ten industrial sectors: adhesive manufacturing, foundries, latex processing, metalworking, plywood/veneer milling, ricemilling, rubber tire manufacturing, sawmilling, shoemaking, and textile related industries. At each work site, aerosol particle size distributions and concentrations of formaldehyde, benzene, toluene, isopropyl alcohol, and furfural were measured. Mean aerosol particle concentrations ranged from 61 micrograms/m3 in foundries to 5,578 micrograms/m3 in ricemills, with five industries (adhesives, metalworking, ricemilling, sawmilling, and shoemaking) exceeding the US EPA 24-hr ambient air standard for PM-10. Formaldehyde concentrations exceeded the threshold limit value (TLV) in adhesives factories. Other vapours and elements measured were well below TLVs.

Matched MeSH terms: Air Pollutants, Occupational/adverse effects*
Fulltext Metal dust exposure and lung function deterioration among steel workers: an exposure-response relationship

Hamzah NA, Mohd Tamrin SB, Ismail NH

Int J Occup Environ Health, 2016 07;22(3):224-232.
PMID: 27392157 DOI: 10.1080/10773525.2016.1207040

BACKGROUND: Metallic dust is a heterogeneous substance with respiratory sensitizing properties. Its long term exposure adversely affected lung function, thus may cause acute or chronic respiratory diseases.
METHODS: A cross-sectional study was conducted in a steel factory in Terengganu, Malaysia to assess the metal dust exposure and its relationship to lung function values among 184 workers. Metal dust concentrations values (Co, Cr, and Ni) for each worker were collected using air personal sampling. Lung function values (FEV1, FVC, and %FEV1/FVC) were determined using spirometer.
RESULTS: Exposure to cobalt and chromium were 1-3 times higher than permissible exposure limit (PEL) while nickel was not exceeding the PEL. Cumulative of chromium was the predictor to all lung function values (FEV1, FVC, and %FEV1/FVC). Frequency of using mask was positively associated with FVC (Adj b = 0.263, P = 0.011) while past respiratory illnesses were negatively associated with %FEV1/FVC (Adj b = -1.452, P = 0.026). Only few workers (36.4%) were found to wear their masks all times during the working hours.
CONCLUSIONS: There was an exposure-response relationship of cumulative metal dust exposure with the deterioration of lung function values. Improvement of control measures as well as proper and efficient use or personal protection equipment while at work could help to protect the respiratory health of workers.

Matched MeSH terms: Air Pollutants, Occupational/adverse effects*