Displaying publications 1 - 20 of 189 in total

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  1. Phua CS, Moffat B, Paul E, Ang M, Law M, Bertram K, et al.
    Magn Reson Imaging, 2023 Nov;103:156-161.
    PMID: 37517766 DOI: 10.1016/j.mri.2023.07.013
    T2 relaxation times (T2 times) are different between resting and exercised muscles and between muscles of healthy subjects and subjects with muscle pathology. However, studies specifically focusing on neck muscles are lacking. Furthermore, normative neck muscle T2 times are not well defined and methodology used to analyse T2 times in neck muscles is not robust. We analysed T2 times in key neck muscles and explored factors affecting variability between muscles. 20 healthy subjects were recruited. Two circular regions of interest (ROIs) were drawn in two mutually exclusive regions within neck muscles on T2 weighted images and values averaged. ROI measurements were performed by a co-investigator, supervised by a neuro-radiologist. For the first ten subjects, measurements were done from C1-T1. For the remaining subjects, ROIs were drawn at two pre-determined levels. Two MRIs were repeated at 31 degrees acquisition to evaluate the effect of muscle fibre orientation. ROI values were translated into T2 times. Results showed semispinalis capitis had the longest T2 times (range 46.88-51.42 ms), followed by splenius capitis (range 47.37-48.33 ms), trapezius (range 45.27-47.46 ms), levator scapulae (range 43.17-45.63 ms) and sternocleidomastoid (range 38.45-42.91 ms). T2 times did not vary along length of muscles and were unaffected by muscle fibre orientation (P > 0.05). T2 times of splenius capitis correlated significantly with age at C2/C3 and C5/C6 levels and trapezius at C7/T1 level. Gender did not influence relaxation times (P > 0.05). In conclusion, results of normative neck muscle T2 time values and factors influencing the T2 times could serve as a reference for future MR analysis of neck muscles. The methodology used may also be useful for related studies of neck muscles.
    Matched MeSH terms: Healthy Volunteers
  2. Fisher JA, Bompart F, Montrasio L, Mwale S, Chew CK, Kurundkar SB, et al.
    Lancet, 2024 Aug 17;404(10453):651.
    PMID: 39153805 DOI: 10.1016/S0140-6736(24)01480-6
    Matched MeSH terms: Healthy Volunteers*
  3. Halling E
    Nurs Times, 1972 Aug 3;68(31):976-7.
    PMID: 5044373
    Matched MeSH terms: Volunteers*
  4. Munjir N, Othman Z, Zakaria R, Shafin N, Hussain NA, Desa AM, et al.
    EXCLI J, 2015;14:801-8.
    PMID: 26600750 DOI: 10.17179/excli2015-280
    This study aims to develop two alternate forms for Malay version of Auditory Verbal Learning Test (MAVLT) and to determine their equivalency and practice effect. Ninety healthy volunteers were subjected to the following neuropsychological tests at baseline, and at one month interval according to their assigned group; group 1 (MAVLT - MAVLT), group 2 (MAVLT - Alternate Form 1 - Alternate Form 1), and group 3 (MAVLT - Alternate Form 2 - Alternate Form 2). There were no significant difference in the mean score of all the trials at baseline among the three groups, and most of the mean score of trials between MAVLT and Alternate Form 1, and between MAVLT and Alternate Form 2. There was significant improvement in the mean score of each trial when the same form was used repeatedly at the interval of one month. However, there was no significant improvement in the mean score of each trial when the Alternate Form 2 was used during repeated neuropsychological testing. The MAVLT is a reliable instrument for repeated neuropsychological testing as long as alternate forms are used. The Alternate Form 2 showed better equivalency to MAVLT and less practice effects.
    Matched MeSH terms: Healthy Volunteers
  5. Fernandez-Llimos F, Pharmacy Practice 2018 peer reviewers
    Pharm Pract (Granada), 2019 03 21;17(1):1502.
    PMID: 31015883 DOI: 10.18549/PharmPract.2019.1.1502
    Selecting peer reviewers is a crucial stage of the editorial process that ensures the quality of scholarly publications. An alternative to selecting peer reviewers from data bases created with expressions of interest of volunteers consists in systematically searching PubMed for similar articles and inviting their authors to act as peer reviewers. Although this process might identify more appropriate peers, it also can increase the time of the editorial process. In 2018, Pharmacy Practice had to invite 4.70 (SE=0.33) potential reviewers per one accepting. The time from the first reviewer invitation to the last reviewer report received was 61 days (SE=2.1). These figures confirm the existence of a peer review crisis which is significantly increasing the publication delay.
    Matched MeSH terms: Volunteers
  6. Mohd Yusof SA, Mohd Noor N, Othman N
    J Infect Public Health, 2021 Jan;14(1):1-5.
    PMID: 33341478 DOI: 10.1016/j.jiph.2020.11.004
    BACKGROUND: This study will explore and understand the experience of doctors volunteering online in managing the boundaries between work and family in health virtual communities (HVC).

    METHODOLOGY: A qualitative case study approach was used to explore and understand how doctors volunteering online balances between work and family in a Health Virtual Community called DoktorBudak.com (DB). A total of seventeen (17) doctors were interviewed using either face-to-face, Skype, phone interview or through email.

    RESULTS: The results of this study suggested that doctors perceived the physical border at their workplace as less permeable though the ICT has freed them from the restriction to perform other non-related work (such as online volunteering (OV) works) during working hours. In addition, doctors OV use ICTs to perform work at home or during working hours, they perceive their work and family borders as flexible. Furthermore, the doctors used different strategies when it came to blending, whether to segment or integrate their work and family domains.

    CONCLUSION: This study has defined issues on work-family balance and OV. Most importantly this study had discussed the conceptual framework of work-family balance focusing on doctors volunteering online and how they have incorporated ICTs such as Internet technology to negotiate the work-family boundaries, which are permeable, flexible and blending.

    Matched MeSH terms: Volunteers
  7. Samsiah Jayos, Faizah Abd Ghani, Lokman Mohd Tahir, Kamarul Azmi Jasmi, Nur Fatihah Abdullah Bandar
    MyJurnal
    It is significant for the reverts to have an existing helping organization. Therefore, this study aims to identify organizational issues that are directly and indirectly involved with counsellors at the Council of Islamic Religious Department in Malaysia. This study utilizes a qualitative approach by using the case study method. This study involved five (5) counsellors from Council of Islamic Religious Department in Malaysia. This study used the N'Vivo 10.0 for the data analysis to develop themes and sub-themes that related to this study. The findings showed that there are two (2) sub themes involved both government and non-government. There are six (6) sub-sub themes for the government which are Jabatan Agama Islam, Jabatan Mufti, Pusat Dakwah Islamiah, Pusat Kaunseling MAINS Negeri Sembilan, Jabatan Kehakiman and Baitulmal. While, non-government has ten (10) sub-sub themes; Lembaga Kaunselor Malaysia, Unit Saudara Baru, Unit Ukhuwah, Pusat Saudara Baru Darul Saadah, Darul Ukhuwah Yayasan Kasih Sayang, Volunteer Body, Malaysian Chinese Muslim Association (MACMA), Pertubuhan Kebajikan Islam Malaysia (PERKIM), PERKAMA and Skuad Mubaligh Seremban. In conclusion, this study could be used as a guide for counsellors to provide guidance and counselling services to revert clients.
    Matched MeSH terms: Volunteers
  8. Karen-Ng, L.P., Hassan, S., Marhazlinda, J., Zain, R.B., Choon, Y.F.
    Ann Dent, 2012;19(2):62-65.
    MyJurnal
    The purpose of this study was to determine the
    DNA yield and quality from different non-invasive
    sampling methods and to identify the method which
    gave the highest DNA yield. Method: Thirty-eight
    volunteers had been recruited in this study where
    blood, buccal cells and saliva were collected using
    various collection techniques. Buccal cells were
    collected by 1) cytobrush and 2) saline mouth rinsing
    or “swish”. Meanwhile saliva was collected by passive
    drooling method. Upon processing the white blood
    cell (WBC), buccal cells and saliva samples, DNA
    extraction was performed according to the
    manufacturer’s protocol. Quantification and quality
    (DNA ratio at A260/A280) of the extracted DNA were
    determined using NanoDropND-1000®. T-test was
    performed to compare means between DNA obtained
    from various collection methods. Results: DNA yields
    from buccal cells collected with cytobrush, “swish”,
    saliva and WBC (mean ± SD) were (8.2 ± 5.9)ng/μl,
    (28.2 ± 14.9)ng/μl, (5.9 ± 9.5)ng/μl and (105.3 ±
    75.0)ng/μl respectively. Meanwhile the mean DNA
    ratio at A260/A280 for cytobrush, “swish”, saliva and
    WBC were 2.3, 2.0, 1.7 and 1.8 respectively. Post hoc
    test with Bonferroni correction suggested that DNA
    yield from “swish” technique exhibited the least mean
    different as compared to the DNA extracted from WBC
    (p
    Matched MeSH terms: Volunteers
  9. Sharma N, Khanna K, Kumar N, Karwasra R, Janakiraman AK, Rajagopal MS
    Assay Drug Dev Technol, 2023 Oct;21(7):325-330.
    PMID: 37801663 DOI: 10.1089/adt.2023.053
    An alternative to oral administration for the delivery of therapeutic substances is the topical route, which frequently has comparable efficacy but may have a better tolerability profile. Gamma scintigraphy is a noninvasive technique that involves the application of radioactive substances to conduct biodistribution studies of therapeutic substances delivered through various routes. Nimesulide (NSD) was radiolabeled with technetium pertechnetate (Technetium99m [99mTc]) and this radiolabeled drug complex (99mTc-NSD) was used to prepare a topical gel formulation. The permeation of the radiolabeled drug from the topical gel was determined by gamma scintigraphy on human volunteers. The region of interest was calculated for the quantification of permeated radiolabeled drugs. This was observed that the mean percentage permeation of 99mTc-NSD was found to be 0.32 ± 0.22 to 36.37 ± 2.86 at 5 and 240 min. It was demonstrated that gamma scintigraphy may be a noninvasive and reliable technique for the determination of drug permeation through topical routes.
    Matched MeSH terms: Healthy Volunteers
  10. Bompart F, Fisher JA, Allen E, Sevene E, Kumar N, Chew CK, et al.
    Nat Med, 2023 Oct;29(10):2393-2394.
    PMID: 37580535 DOI: 10.1038/s41591-023-02490-6
    Matched MeSH terms: Healthy Volunteers
  11. Lee YY, Erdogan A, Yu S, Dewitt A, Rao SSC
    J Neurogastroenterol Motil, 2018 Jul 30;24(3):460-468.
    PMID: 29879762 DOI: 10.5056/jnm17081
    Background/Aims: Whether high-resolution anorectal pressure topography (HRPT), having better fidelity and spatio-temporal resolution is comparable to waveform manometry (WM) in the diagnosis and characterization of defecatory disorders (DD) is not known.

    Methods: Patients with chronic constipation (Rome III) were evaluated for DD with HRPT and WM during bearing-down "on-bed" without inflated rectal balloon and "on-commode (toilet)" with 60-mL inflated rectal balloon. Eleven healthy volunteers were also evaluated.

    Results: Ninety-three of 117 screened participants (F/M = 77/16) were included. Balloon expulsion time was abnormal (> 60 seconds) in 56% (mean 214.4 seconds). A modest correlation between HRPT and WM was observed for sphincter length (R = 0.4) and likewise agreement between dyssynergic subtypes (κ = 0.4). During bearing down, 2 or more anal pressure-segments (distal and proximal) could be appreciated and their expansion measured with HRPT but not WM. In constipated vs healthy participants, the proximal segment was more expanded (2.0 cm vs 1.0 cm, P = 0.003) and of greater pressure (94.8 mmHg vs 54.0 mmHg, P = 0.010) during bearing down on-commode but not on-bed.

    Conclusions: Because of its better resolution, HRPT may identify more structural and functional abnormalities including puborectal dysfunction (proximal expansion) than WM. Bearing down on-commode with an inflated rectal balloon may provide additional dimension in characterizing DD.

    Matched MeSH terms: Healthy Volunteers
  12. Wagner NN
    J Soc Psychol, 1968 Feb;74(1):133-4.
    PMID: 5640245
    Matched MeSH terms: Volunteers*
  13. Han H, Meng B, Chua BL, Ryu HB
    PMID: 32927834 DOI: 10.3390/ijerph17186594
    International volunteer tourism is an emerging and sustainable trend of the global tourism industry. In this study, we attempted to provide a clear comprehension of volunteer tourists' mental health increase and pro-social intention formation. A survey method and quantitative approach were used. Our result from the structural analysis showed that hedonic and utilitarian performances, mental health, and volunteer tourism engagement had significant associations and that these relationships contributed to improving pro-social intention. In addition, results from the metric invariance assessment revealed that the volunteer tourism engagement and pro-social intention relation was under the significant influence of problem awareness and ascribed responsibility. Mental health and engagement acted as significant mediators. The comparative importance of volunteer tourism engagement was uncovered. Overall, our results provided a sufficient understanding of volunteer tourists' pro-social decision-making process and behaviors.
    Matched MeSH terms: Volunteers/psychology*
  14. Chung MH, Hazmi H, Cheah WL
    J Environ Public Health, 2017;2017:9610928.
    PMID: 28286530 DOI: 10.1155/2017/9610928
    The objective of this study was to assess the role performance among KOSPEN community health volunteer in Kuching district and its associated factors. This was a cross-sectional study, conducted in 21 localities in Kuching with a total of 210 respondents. Data were collected using validated interviewer-administered questionnaires and analyzed using SPSS version 22.0. The respondents comprised 55.2% females, 81.9% married, and 41.4% aged above 45 and above and 72.4% completed their education up to secondary school. The result revealed that 59.0% of the respondents agreed and understood their role performances. Multiple Logistics analysis revealed that factors associated with role performance were age group (p = 0.003), education level (p < 0.001), marital status (p = 0.025), prestige and respect (p = 0.012), being seen as "doctor" in community (p = 0.003), job aids (p = 0.009), training location (p = 0.001), and supervision by community (p < 0.001). To increase and maintain the work performance of CHVs, commitment from the government, policy makers, stakeholders, and the communities is required.
    Matched MeSH terms: Volunteers/statistics & numerical data*
  15. Curran DJ, Rubin L, Towler MR
    PMID: 26327784 DOI: 10.4137/CMAMD.S29061
    An off-the-shelf Raman Spectrometer (RS) was used to noninvasively determine the presence of monosodium urate (MSU) crystals on the metatarsophalangeal joint (MTPJ) of a single gout sufferer. The spectrum sourced from the clinically diagnosed gout sufferer was compared to that sourced from an age-matched healthy subject scanned using the same protocol. Minimal signal processing was conducted on both spectra. Peaks characteristic of MSU crystals were evident on the spectrum sourced from the gout sufferer and not on the spectrum from the healthy control.

    Study done in Canada
    Matched MeSH terms: Healthy Volunteers
  16. Khamis, N.K., Deros, B.M
    MyJurnal
    Driving posture is important to determine the comfortability of the driver. The purpose of this study is to investigate the muscle response in car pedal operation. To evaluate this response, 11 volunteers involved in simulated driving experiment using an electrical impedance myography to detect the muscle contraction of the lower leg, particularly at Gastrocnemius medial (GM). The driver requires to perform different pedal actions. The results depict that GM muscle shows different reaction according to pedal actions. According to these results, different degree of ankle angle lead to different muscle response. These findings help us to understand the effect of physical attribute related to muscle response and joint angle on driver during monotonous driving task.
    Matched MeSH terms: Volunteers
  17. Sai-Guan L, Husain S, Zahedi FD, Ahmad N, Gendeh BS
    Iran J Otorhinolaryngol, 2020 Jul;32(111):213-222.
    PMID: 32850509 DOI: 10.22038/ijorl.2019.34346.2138
    Introduction: Sniffin' Sticks smell identification test is a tool used for evaluation of olfactory function but the results are culture-dependent. It relies on the subject's familiarity to the odorant and descriptors. This study aims to develop the Malaysian version of Sniffin' Sticks smell identification test suitable for local population usage.

    Materials and Methods: The odorant descriptors and distractors of the original version of Sniffin' Sticks were translated into Malay language. It was then tested for familiarity and identifiability in 30 normosmic subjects. The descriptors were replaced until the familiarity of all descriptors and identification rates of odorants achieved ≥ 70%. The validity of the new cultural-adapted version was tested in 60 hypo-anosmic subjects and 60 normosmic subjects with Student t-test. The test-retest reliability was evaluated after two weeks with interclass correlation.

    Results: Two odorant descriptors and nine distractors achieved familiarity <70% (13.3% - 66.7%) and were replaced. Another three culturally inappropriate distractors were also replaced. The mean score among the healthy subjects was significantly higher than the subject with smell dysfunction [13.7 (1.12) and 7.3 (3.42); t = 7.24 (df = 34.23), P<0.001]. The coefficient of correlation (r) between test and retest scores was 0.93 (P<0.001).

    Conclusion: The cultural adapted Malaysian version of Sniffin' Sticks smell identification test is valid and has high test-retest reliability. This is the first smell identification test validated in Malaysia. It is effective for evaluation of olfactory function in local population.

    Matched MeSH terms: Healthy Volunteers
  18. Rosli, Y., Maddess, T.L., James, A.C., Goh, X.L.
    ASM Science Journal, 2009;3(1):31-37.
    MyJurnal
    Responses were recorded from normal healthy subjects and age-related macular degeneration (AMD) patients and evaluated, using a new variant of mfVEP. Subjects information was recorded using 64 EEG channels with a computer-based acquisition system. The stimulus layout was a 84 region corticallyscaled dartboard comprising 12 sectors and seven concentric rings subtending a diameter of 23º, presented dichoptically at 60 Hz. Data from the control and AMD patients were statistically compared when fitted concurrently into the multiple regression analysis. The Pattern-pulse mfVEP technique could distinguish between normal eyes and those with a definite diagnosis of dry and wet AMD when responses from the macula were considered.
    Matched MeSH terms: Healthy Volunteers
  19. Mohamed Hatta Shaharom
    ASEAN Journal of Psychiatry, 2009;10(1):83-88.
    MyJurnal
    This is a personal experience with MERCY Malaysia’s Team 7 during its sixday sojourn in Gaza immediately after the 22-day war. It was a mission cut short. We were asked to evacuate as Israel intensified its shelling. This paper is divided into two main parts: First, my observations as a psychiatrist and humanitarian volunteer; and second, a plan for a psychosocial programme in
    Gaza.
    Matched MeSH terms: Volunteers
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