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  1. Lee WW, Tajunisah I, Sharmilla K, Peyman M, Subrayan V
    Invest Ophthalmol Vis Sci, 2013 Nov;54(12):7785-92.
    PMID: 24135757 DOI: 10.1167/iovs.13-12534
    We determined structural retinal nerve fiber layer (RNFL) changes in schizophrenia patients and established if the structural changes were related to the duration of the illness using spectral-domain optical coherence tomography (SD-OCT).
    Matched MeSH terms: Retinal Diseases/physiopathology
  2. Cheah CK, Vijaya Singham N, Gun SC
    Int J Rheum Dis, 2017 Dec;20(12):2253-2255.
    PMID: 26864240 DOI: 10.1111/1756-185X.12827
    Matched MeSH terms: Retinal Diseases/physiopathology
  3. Mohamad NA, Yong MH, Mohd Khialdin S, Bastion MC
    Optom Vis Sci, 2024 Nov 01;101(11):677-682.
    PMID: 39514396 DOI: 10.1097/OPX.0000000000002194
    SIGNIFICANCE: Acute macular neuroretinopathy (AMN) is a rare disease that causes transient or permanent visual disturbance. The exact etiology remains unknown, but vascular compromise of the deep retinal capillary plexus was postulated as the main mechanism. Retinal vascular event post-coronavirus disease 2019 (COVID-19) infection is recently highlighted during the pandemic, which includes AMN.

    PURPOSE: To report a case of AMN post-COVID-19 infection.

    CASE REPORT: A 24-year-old Indian woman presented with acute-onset painless bilateral central scotoma for a day. The symptom was preceded by a history of COVID-19 infection 3 weeks prior. Ocular examination revealed a near-normal visual acuity for both eyes. Fundus examination showed bilateral dull foveal reflex with mild scattered cotton wool spot and vascular tortuosity. Optical coherence tomography macula revealed a distinct short hyperreflective band involving the outer plexiform and outer nuclear layers nasal to the fovea. The Bjerrum perimetry test revealed central scotoma temporal to the fixation. Optical coherence tomography lesions and scotomas are identical and congruous in both eyes. Serial fundus photographs are captured showing the evolving changes of near-normal macula to pigmented wedge-shaped petaloid lesions around the fovea. The patient was diagnosed as bilateral AMN and treated with oral prednisolone. On subsequent follow-up, the central scotoma improved.

    CONCLUSIONS: This case illustrates a clear temporal and possible causal relationship of COVID-19 infection with AMN. Further studies and data are required to justify its association, but the rising cases of AMN shall be anticipated as COVID-19 infections have become endemic worldwide.

    Matched MeSH terms: Retinal Diseases/physiopathology
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