Displaying all 9 publications

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  1. Sivalingam N
    Ann Acad Med Singap, 2004 Nov;33(6):706-10.
    PMID: 15608822
    Concerns about professionalism in medicine have made necessary the explicit teaching and learning of ethics, professionalism and personal development. The noble profession of medicine, taken up as a "calling" by those who are expected to put the needs of the patient above their own, appears to have become a fees-for-service business model and trade. Parental expectations, the diminishing sense of responsibility in teachers, lack of role models, technological advancements, sub-specialisation and third-party involvement in the healthcare delivery system have been identified as reasons for these concerns. The General Medical Council in the United Kingdom, and other professional bodies in both Europe and the Americas, have emphasised the need to enhance the teaching and learning of professionalism in medical schools, particularly the development of good attitudes, appropriate and competent skills, and the inculcation of a value system that reflects the tenets of professionalism in medicine. The medical curriculum will need to be scrutinised so as to introduce the subject of professionalism at all levels of training and education. Barriers to learning professionalism have been identified and students need to be equipped to resolve conflicts and to put the needs of others above their own.
    Matched MeSH terms: Clinical Medicine/education*; Clinical Medicine/standards*
  2. Cheong I
    Family Practitioner, 1987;10(2):7-11.
    Matched MeSH terms: Clinical Medicine
  3. Cherian S, Hacisayidli KM, Kurian R, Mathews A
    J Pharm Pharmacol, 2023 Mar 12;75(3):301-327.
    PMID: 36757388 DOI: 10.1093/jpp/rgac105
    OBJECTIVES: Increasing literature data have suggested that the genus Polygonum L. possesses pharmacologically important plant secondary metabolites. These bioactive compounds are implicated as effective agents in preclinical and clinical practice due to their pharmacological effects such as anti-inflammatory, anticancer, antidiabetic, antiaging, neuroprotective or immunomodulatory properties among many others. However, elaborate pharmacological and clinical data concerning the bioavailability, tissue distribution pattern, dosage and pharmacokinetic profiles of these compounds are still scanty.

    KEY FINDINGS: The major bioactive compounds implicated in the therapeutic effects of Polygonum genus include phenolic and flavonoid compounds, anthraquinones and stilbenes, such as quercetin, resveratrol, polydatin and others, and could serve as potential drug leads or as adjuvant agents. Data from in-silico network pharmacology and computational molecular docking studies are also highly helpful in identifying the possible drug target of pathogens or host cell machinery.

    SUMMARY: We provide an up-to-date overview of the data from pharmacodynamic, pharmacokinetic profiles and preclinical (in-vitro and in-vivo) investigations and the available clinical data on some of the therapeutically important compounds of genus Polygonum L. and their medical interventions, including combating the outbreak of the COVID-19 pandemic.

    Matched MeSH terms: Clinical Medicine*
  4. Elango S, Arumainayagam GC, Palaniappan SP
    Med Teach, 1991;13(1):63-6.
    PMID: 1865800
    The University Science Malaysia, Penang, the third medical school in Malaysia, is following an integrated curriculum. In this curriculum, the students are taught the subject of otolaryngology from the second year of their course unlike the traditional schools where they are taught in the fourth or fifth year. This paper describes how otolaryngology is introduced in this integrated, problem-based curriculum.
    Matched MeSH terms: Clinical Medicine/education
  5. Loh LC
    Respirology, 2018 12;23(12):1198-1199.
    PMID: 30084515 DOI: 10.1111/resp.13382
    Matched MeSH terms: Clinical Medicine*
  6. Loh KY, Kwa SK
    Med Educ, 2009 Nov;43(11):1101-2.
    PMID: 19874515 DOI: 10.1111/j.1365-2923.2009.03501.x
    Matched MeSH terms: Clinical Medicine/education*
  7. Datta A
    Malays J Med Sci, 2021 Feb;28(1):105-108.
    PMID: 33679226 DOI: 10.21315/mjms2021.28.1.13
    Clinical history taking and physical examination are the essence of clinical medicine. However, the glare of modern diagnostic tools and techniques has overshadowed these basic but indispensable steps of diagnosis. Deterioration of clinical skills is a burning issue in this era due to over-reliance on high-end technology. Poor clinical judgment not only leads to mismanagement but also results in over-utilisation of health care resources. Moreover, with lesser time at the bedside, the physician-patient relationship is also getting compromised.
    Matched MeSH terms: Clinical Medicine
  8. Boettiger DC, Saphonn V, Lee MP, Phanuphak P, Pham TT, Heng Sim BL, et al.
    J Acquir Immune Defic Syndr, 2014 Dec 01;67(4):e131-3.
    PMID: 25197829 DOI: 10.1097/QAI.0000000000000338
    Matched MeSH terms: Clinical Medicine/methods*
  9. Daszak P, Tabor GM, Kilpatrick AM, Epstein J, Plowright R
    Ann N Y Acad Sci, 2004 Oct;1026:1-11.
    PMID: 15604464
    The last three decades have seen an alarming number of high-profile outbreaks of new viruses and other pathogens, many of them emerging from wildlife. Recent outbreaks of SARS, avian influenza, and others highlight emerging zoonotic diseases as one of the key threats to global health. Similar emerging diseases have been reported in wildlife populations, resulting in mass mortalities, population declines, and even extinctions. In this paper, we highlight three examples of emerging pathogens: Nipah and Hendra virus, which emerged in Malaysia and Australia in the 1990s respectively, with recent outbreaks caused by similar viruses in India in 2000 and Bangladesh in 2004; West Nile virus, which emerged in the New World in 1999; and amphibian chytridiomycosis, which has emerged globally as a threat to amphibian populations and a major cause of amphibian population declines. We discuss a new, conservation medicine approach to emerging diseases that integrates veterinary, medical, ecologic, and other sciences in interdisciplinary teams. These teams investigate the causes of emergence, analyze the underlying drivers, and attempt to define common rules governing emergence for human, wildlife, and plant EIDs. The ultimate goal is a risk analysis that allows us to predict future emergence of known and unknown pathogens.
    Matched MeSH terms: Clinical Medicine/trends*
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