Displaying publications 1 - 20 of 655 in total

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  1. Management of haemorrhagic complications of dengue haemorrhagic fever (DHF)
    Ng SC
    Family Physician, 1992;4:27-28.
  2. Bone marrow biopsy
    Ng SC
    Family Physician, 1989;1:64-66.
  3. Anaemia: an approach to diagnosis (what is new is old)
    Ng SC
    Family Physician, 1991;3:5-9.
  4. Management of lymphoma: current approach
    Ng SC
    Family Physician, 1991;3:16-19.
  5. Towards a new role for the infant food industry
    Abraham SCE
    Family Practitioner, 1977;2:61-63.
  6. Disseminated intravascular coagulation
    Ng SC
    Family Practitioner, 1988;11:62-64.
  7. Intramuscular injections of quinine bihydrochloride in simple tertian malaria
    Fox SCG
    Lancet, 1917;190:909-10.
    DOI: 10.1016/S0140-6736(00)54084-7
  8. The practical application of anti-malarial measures on Malayan estates
    Howard SC
    Bull Inst Med Res Kuala Lumpur, 1939.
  9. The demographic and morbidity patterns seen in an outpatient department in a Malaysian General Hospital
    Chan SC
    Family Physician, 1995;7:3-10.
    This study aimed to established baseline data on patients' demographic and morbidity patterns over three months in the Outpatients Department (OPD) Ipoh Hospital. Entry of the first ten thousand patients into a computerised database for analysis showed that the majority were unemployed and from the low income group. There were more Malays and Indians, less Chinese. Respiratory infections accounted for 18.5 % while major chronic diseases (hypertension, diabetes mellitus, asthma) were common. Overall a wide spectrum of illnesses were seen. A career structure for OPD doctors and incorporation of Family Medicine concepts were proposed to improve primary care in OPD.
    Study site: Outpatients Department (OPD), Hospital Ipoh, Perak, Malaysia
  10. Peripheral neuropathy
    Loong SC
    Family Physician, 1989;1:19-21.
  11. Medical partnership contract
    McPherson SC
    Family Practitioner, 1978;3(4):37-37.
  12. Eye emergencies
    Subramaniam SC
    Family Physician, 1989;1:24-26.
  13. Host ethnicity influences non-Hodgkin's lymphoma subtype frequency and Epstein-Barr virus association rate: the experience of a multi-ethnic patient population in Malaysia
    Peh SC
    Histopathology, 2001 May;38(5):458-65.
    PMID: 11422484
    AIMS: The pattern of malignant lymphoma is known to vary in different populations. This study aims to elucidate the effect of ethnicity on subtype frequency of non-Hodgkin's lymphoma and EBV association rate.

    METHODS AND RESULTS: A total of 232 reconfirmed lymphoma cases in Malaysian patients were retrieved from the archives in the Department of Pathology, University Hospital, Kuala Lumpur. There were 24 (10%) Hodgkin's and 208 (90%) non-Hodgkin's lymphomas, 173 of the latter were in adult group (aged > or = 15 years). The ethnic composition were 41 Malays, 107 Chinese, 21 Indians and four none of the above. A male : female ratio of 2.4 : 1 was observed. Complete immunohistochemical studies in 158 cases revealed 36 (23%) T-cell, 121 (76%) B-cell and one (1%) null-cell phenotype. Seventy-five percent of the T-cell lymphomas were peripheral T/NK-cell types. Among the classifiable lesions, low-grade/indolent lymphomas constituted 17%: 2% were the lymphocytic subtype and 10% were follicular lymphomas. Approximately one-third of the follicular lymphomas occurred in Indian patients. The largest group of high-grade lymphoma was diffuse large B-cell type (46%), followed by peripheral T/NK-cell (18%). A predominance of NK/T-cell lymphomas occurred in Chinese (5/7), and all were EBV associated. Burkitt's lymphoma accounted for 5% (eight cases), all were Chinese males, with a 38% EBV-association rate. The frequency of EBV-associated B-cell lymphoma is three times more common in Chinese than Malays. The EBV positivity rate among lymphomas in ethnic Malay, Chinese and Indian patients was 5%, 15% and 22%, respectively, and in T- and B-cell lymphomas was 36% and 7%, respectively.

    CONCLUSIONS: This Malaysian series reveals differences in the subtype frequencies of non-Hodgkin's lymphomas and EBV association rate amongst patients of various ethnic groups residing in the same environment.

  14. Activated recombinant factor VII in the treatment of retroperitoneal haemorrhage in a patient with factor VIII inhibitor
    Ng SC
    Ann Acad Med Singap, 1994 Nov;23(6):901-2.
    PMID: 7741509
    The management of haemorrhagic episodes in patients with factor VIII inhibitor is difficult and the outcome rather unpredictable. The use of an investigational drug, that is, activated recombinant factor VII (rFVIIa) in a young non-haemophiliac patient with spontaneous occurrence of factor VIII inhibitor who presented with life-threatening retroperitoneal haemorrhage is reported. There was prompt achievement of haemostasis with rFVIIa after the patient had failed conventional therapy with factor IX and Autoplex. Two further episodes of retroperitoneal bleeding again responded promptly to rFVIIa therapy.
  15. Fulltext Recombinant factor VII
    Ng SC
    Med J Malaysia, 1995 Dec;50(4):425.
    PMID: 8668070
  16. Carbimazole-induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor--a case report
    Ng SC
    Ann Acad Med Singap, 1995 May;24(3):465-6.
    PMID: 7574435
    Drug-induced agranulocytosis is a potentially fatal complication despite advances in supportive care. A patient with carbimazole-induced agranulocytosis associated with marked depletion of granulocytic precursors in the marrow was treated with granulocyte-macrophage colony stimulating factor (GM-CSF) at a dose of 5 micrograms/kg subcutaneously daily for one week. The absolute neutrophil count rose above 1 x 10(9)/L after one week of GM-CSF therapy. The GM-CSF probably expedited the recovery of the neutrophil count. Further studies are warranted to delineate the role of GM-CSF in the treatment of drug-induced agranulocytosis.
  17. Evans syndrome: a report on 12 patients
    Ng SC
    Clin Lab Haematol, 1992;14(3):189-93.
    PMID: 1451398
    From 1981 to 1989, 12 patients of the University Hospital, Kuala Lumpur, were diagnosed to have Evans syndrome based on direct antiglobulin test (DAT) positive haemolytic anaemia and immune thrombocytopenia occurring either simultaneously (7 patients) or consecutively (5 patients). Their mean age at presentation was 24.8 years with a marked female preponderance. All 12 patients were given high dose steroid after diagnosis. Subsequently, other modalities including intravenous immunoglobulin (1 patient) and high dose methylprednisolone (1 patient) were given. Three patients died of intracranial haemorrhage during the first admission while 1 patient died of pulmonary embolism six months after diagnosis. Three patients had splenectomy because of thrombocytopenia. Six patients tested positive for antinuclear factor and antibodies to double stranded DNA and four of them died. Positive serology appeared to be associated with a poorer prognosis. Follow up observations indicate that patients who survive the acute attacks fare reasonably well.
  18. The paediatric challenge
    Abraham SC
    Med J Malaya, 1970 Dec;25(2):77-8.
    PMID: 4251138
  19. Fulltext Disturbing trends in abortions in Singapore--analysis in a private clinic
    Chew SC
    Singapore Med J, 1988 Feb;29(1):28-9.
    PMID: 3406761
    The figures for abortions performed under The Abortion Act, 1974 of Singapore in a private clinic over a period of 20 months were studied. Overall, an alarming proportion of repeat abortions were found, and this was true for all age groups suggesting that abortions are being used as a regular method of family planning in Singapore.
  20. Fulltext Trends in coronary heart disease mortality in Singapore
    Emmanuel SC
    Singapore Med J, 1989 Feb;30(1):17-23.
    PMID: 2595383
    Coronary heart disease which was responsible for 2.9% of all deaths 30 years ago, today accounts for 19% of deaths. The rising trend which declined in 1985, appears to be stabilising now. Indians have mortality rates which are 3 times that of Chinese. This is the background against which the Singapore Myocardial Infarction Register was set up in 1967 to provide incidence and prevalence data for coronary heart disease in the country. in 1987 to provide incidence and prevalence data for coronary heart disease in the country.
    Key words: Coronary heart disease mortality, Age standardised death rates, Ethnic differences, Singapore Myocardial Infarction Register
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