Thin-walled cylindrical shell storage tanks are pressure vessels in which the walls of the vessel have a thickness that is much smaller than the overall size of the vessel. These types of structures have global applications in various industries, including oil refineries and petrochemical plants. However, these storage tanks are vulnerable to fire and explosions. Therefore, a parametric study using numerical simulation was carried out, considering the internal liquid level, wall thickness, material yield strength, constraint conditions, and blast intensity, with a diameter of 100 m and height of 22.5 m under different blast loads using the finite element analysis method. The thickness of the tank wall is varied as 10 mm, 20 mm, 30 mm, and 40 mm, while the fill level of internal fluid is varied as 25, 50, 75, and 100%. The blast simulation was conducted using LS-DYNA software. The numerical results are then compared with analytical results. The effects of blast intensity, standoff distance, wall thickness, and fill level of internal fluid on the structural behaviour of the storage tank were investigated and discussed.