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  1. Abdurrahman M, Kamal MS, Ramadhan R, Daniati A, Arsad A, Abdul Rahman AF, et al.
    ACS Omega, 2023 Nov 07;8(44):41004-41021.
    PMID: 37970044 DOI: 10.1021/acsomega.3c04450
    The use of different types of chemicals in upstream oilfield operations is critical for optimizing the different operations involved in hydrocarbon exploration and production. Surfactants are a type chemical that are applied in various upstream operations, such as drilling, fracturing, and enhanced oil recovery. However, due to their nonbiodegradability and toxicity, the use of synthetic surfactants has raised environmental concerns. Natural surfactants have emerged because of the hunt for sustainable and environmentally suitable substitutes. This Review discusses the role of natural surfactants in upstream operations as well as their benefits and drawbacks. The Review discusses the basic characteristics of surfactants, their classification, and the variables that affect their performance. Finally, the Review examines the possible applications of natural surfactants in the upstream oil sector and identifies areas that require further research.
  2. Arung ET, Ramadhan R, Mandzilkh LD, Santoso PA, Matsumoto M, Nagata M, et al.
    Malays J Med Sci, 2022 Oct;29(5):146-153.
    PMID: 36474534 DOI: 10.21315/mjms2022.29.5.15
    The broader objective of this study is to identify natural materials that might inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We have focused on stingless bee honey, which has a unique taste that is both sweet and sour and sometimes bitter. We screened 12 samples of honey from 11 species of stingless bees using an angiotensin-converting enzyme 2 (ACE2)-spike protein-binding assay and phytochemical analysis. Ten of the samples showed inhibition above 50% in this assay system. Most of the honey contained tannins, alkaloids, flavonoids, triterpenoids, carotenoids and carbohydrates. Our findings in this in vitro study showed that honey from stingless bees may have a potent effect against SARS-CoV-2 infection by inhibiting the ACE2-spike protein-binding.
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