Introduction Breast cancer is ranked number one from the ten most frequent cancers in
female, Peninsular Malaysia. Various studies provide negative evidence on
malignancies and one of the end results is impaired quality of life (QOL).
Studies show lifestyle approaches are key factors in enhancing the QOL
among cancer survivors. The purpose of this study is to describe the lifestyle
practices (LP) among breast cancer survivors (BCS) which consist of dietary
intake, exercise habits, and stress management and to determine whether
these practices have influence on the QOL among Malaysian BCS.
Methods This study adopts a cross-sectional study design using a self-administered
questionnaire. A total of 280 BCS from public and private hospitals
throughout Peninsular Malaysia had participated. The questionnaire covers
QOL and LP items which consist of dietary intake (consumption of high-fat
food, high-fibre food, fruits and vegetables), exercise habits, and stress
management. Descriptive statistics and one-way ANOVA were used to
determine the relationship between LP and QOL.
Results Mean age of the study sample was at 41 (SD=7.37). Majority of them were
Malay (74%), 53% were diagnosed with breast cancer between 1 to 2 years
whereas 54% were presented with stage 2 at diagnosis. There was a
statistically significant difference (p
Introduction This study investigates work engagement of employed breast cancer
survivors in comparison to unmatched control samples of healthy working
women without cancer and any other chronic diseases from the general
population.
Methods A case-control study design using unmatched controls was adopted in this
study. The case comprised of 80 female breast cancer survivors who have
returned to full-time employment selected using purposive sampling
technique. Meanwhile, controls were 88 healthy female working women in
full time paid employment, selected using quota sampling. Questionnaire
covering socio-demographic characteristics and self-rated work engagement
measured using Utrecht Work Engagement Scale (UWES) was distributed to
the cancer survivors through face-to-face meeting during their hospital visits.
For the healthy controls the questionnaires were distributed using drop-andcollect
method through the human resource personnel of the participating
organization.
Results The results revealed, after controlling for age, marital status, ethnic group and
tenure with organization, no significant differences in the overall work
engagement was found between the breast cancer survivors [mean (SD) =
4.66 (0.92)] and the healthy controls [mean (SD) = 4.75 (0.85)]; F(1, 163)
=1.70. In comparison to the work engagement domains, only the Vigor
domain was found to be significantly lower for the survivors, survivors [F (1,
163) =14.94; p
The incidence of breast cancer has been on the rise in Malaysia. It is suggested that a subset of breast cancer cases were associated with germline mutation in breast cancer susceptibility (BRCA) genes. Most of the BRCA mutations reported in Malaysia were point mutations, small deletions and insertions. Here we report the first study of BRCA large genomic rearrangements (LGRs) in Malaysia. We aimed to detect the presence of LGRs in the BRCA genes of Malaysian patients with breast cancer.