Urban air quality studies have primarily focused on pollutant dispersion; however, spatial or temporal concentrations collected at discretely distributed grid points (or fixed receptors) do not reflect the actual pollutant exposure of pedestrians. Using large-eddy simulation (LES) with virtual walkers implemented, this study investigates pollutant exposure of walking agents (or moving receptors) in an urban turbulent boundary-layer flow developed over an aligned building array under the influence of different wind directions. The spatial variability of the exposure risks are found to be better captured by the moving receptors than the fixed receptors along the same agent walking tracks. We demonstrate that the actual exposure can differ significantly from results interpreted from data recorded by the fixed receptors (corresponding to Eulerian estimates) and show that large discrepancies occur in avenues near the source, wherein dispersion of the point release has not occurred on larger spatiotemporal scales. In most scenarios, optimal evacuation routes are shown to be ones that deviate as much as possible from the dominant wind direction; however, one needs to decide the priority of moving to further avenues first or immediately adjusting the walking direction. The results should serve as a useful baseline reference for environmental health impact assessment and evacuation route planning against hazardous releases of air pollutants in more complex urban environments.
We report a six-year-old Malay girl who presented with a right retroperitoneal tumour that measured 7.5 cm in diameter. A wide excision of the lesion was performed. The tumour was separated from a normal-appearing right kidney by a capsule. Microscopically, this well-encapsulated tumour was composed of classical triphasic components: epithelial, mesenchymal and blastemal areas. The immunohistochemical study showed WT1 expression in the blastemal area. Thus, a diagnosis of Wilms' tumour with favourable histology was made. The patient was well for 12 months. Extrarenal Wilms' tumour is uncommon, with the majority of cases occurring in the retroperitoneal and inguinal areas. Wilms' tumour that is not arising from the intrarenal area but shares a common capsule with the ipsilateral kidney, is even rarer. Indeed, our case would be more appropriately classified as juxtarenal/pararenal Wilms' tumour. Despite its rarity, an extrarenal or even juxtarenal/pararenal Wilms' tumour should be included in the differential diagnosis of retroperitoneal tumour.