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  1. Nettem S, Nettemu SK, Basha K, Venkatachalapathi S
    Dent Res J (Isfahan), 2014 Jul;11(4):513-7.
    PMID: 25225567
    Dentin dysplasia is an exceptionally rare, autosomal-dominant, hereditary condition, primarily characterized by defective dentin formation affecting both the deciduous and permanent dentitions. The etiology remains imprecise to date, in spite of the numerous hypotheses put forward and the constant updates on this condition. This case report of type I dentin dysplasia exhibits radiographic findings that are unique and diverse from the classical findings of various subtypes of this disease reported to date. This article also depicts the implant-based oral rehabilitation of the young patient diagnosed with this variant model of dentin dysplasia type I. Early diagnosis and implementation of this preventive and curative therapy is vital for avoiding premature exfoliation of deciduous and permanent dentition and the associated residual ridge resorption, thereby overcoming functional and esthetic deficits and ensuring protection of the remaining dentition from further harm.
  2. Thomas AR, Mathew M, Nettemu SK, Mayya A
    Cureus, 2023 Nov;15(11):e49717.
    PMID: 38161818 DOI: 10.7759/cureus.49717
    The pulp and the periodontium are inherently interconnected, both anatomically and functionally. Conditions affecting the periodontium and the pulp can create challenges in diagnosis, treatment strategizing, and predicting outcomes. This case report outlines the combination of resection and regeneration techniques utilizing mineral trioxide aggregate (MTA) and bone grafting to address a persistent periapical lesion in a maxillary premolar. The treatment led to the effective alleviation of the patient's symptoms and successful regeneration.
  3. Mathew M, Nayak V, Nettemu SK, Ong TYD
    BMJ Case Rep, 2024 Jun 25;17(6).
    PMID: 38925668 DOI: 10.1136/bcr-2024-260402
  4. Singh VP, Gan JY, Liew WL, Kyaw Soe HH, Nettem S, Nettemu SK
    Dent Res J (Isfahan), 2019 2 13;16(1):29-35.
    PMID: 30745916
    Background: Periodontitis is a public health concern since it is a major factor in tooth loss worldwide and has association with many systemic diseases. Sleep is a complex and essentially biological process and a critical factor for maintaining mental and physical health. Since inflammation is characteristic of both chronic periodontitis and sleep deprivation, few studies in recent years present the contradictory results regarding this potential association. The objective of the present study was to investigate the association between quality of sleep and chronic periodontitis.

    Materials and Methods: A total of 200 individuals participated in this study. All participants underwent a comprehensive clinical periodontal examination. Case-control were identified using the Centers for Disease Control and Prevention/American Academy of Periodontology case definitions for periodontal disease. The quality of sleep was assessed by Pittsburgh Sleep Quality Index. The univariate and multivariate logistic regression analysis was used to test the influence of variables (quality of sleep, age, sex, ethnicity, education, and socioeconomic status), in the occurrence of periodontitis. Odds ratio (OR) and respective confidence intervals (CIs) were calculated and reported. P =0.05 was considered statistically significant.

    Results: The prevalence of poor quality of sleep was 56.75% in cases (periodontitis group) and 43.24% in control group. There was positive association between quality of sleep and chronic periodontitis (OR = 3.04; 95% CI = 1.42-6.5; P = 0.004). In multivariate logistic regression analysis, only the age was significantly related to the periodontitis (OR = 1.11; 95% CI = 1.07-1.41; P < 0.001), other variables failed to reach the significant level.

    Conclusion: Poor quality of sleep was significantly associated with chronic periodontitis. Only the age was significantly related to periodontitis among the other covariable measured.
  5. Singh VP, Nettemu SK, Nettem S, Hosadurga R, Nayak SU
    J Hum Reprod Sci, 2017 Jul-Sep;10(3):162-166.
    PMID: 29142443 DOI: 10.4103/jhrs.JHRS_87_17
    Ample evidence strongly supports the fact that periodontal disease is a major risk factor for various systemic diseases namely cardio-vascular disease, diabetes mellitus, etc. Recently, investigators focussed on exploring the link between chronic periodontitis (CP) and erectile dysfunction (ED) by contributing to the endothelial dysfunction. Both the diseases share common risk factors. Various studies conducted in different parts of the world in recent years reported the evidence linking this relationship as well as improvement in ED with periodontal treatment. Systemic exposure to the periodontal pathogen and periodontal infection-induced systemic inflammation was thought to associate with these conditions. The objective of this review was to highlight the evidence of the link between CP and ED and the importance of oral health in preventing the systemic conditions.
  6. Nettemu SK, Nettem S, Singh VP, William SS, Gunasekaran SS, Krisnan M, et al.
    Int J Implant Dent, 2021 06 10;7(1):77.
    PMID: 34109477 DOI: 10.1186/s40729-021-00315-0
    AIM: This study was to evaluate the association between peri-implant bleeding on probing in peri-implant diseases and its association with multilevel factors (site specific factors, implant factors, and patient level factors).

    METHODOLOGY: A cross-sectional study involved consented adult patients with ≥ 1 dental implant. Two calibrated operators examined the patients. BoP was outcome variable and peri-implant gingival biotype was principal predictor variable. The effects of site, implant, and patient level factors on BoP were assessed using a multilevel logistic regression model.

    RESULTS: Eighty patients for a total of 119 implants and 714 sites were included in the study. Bleeding on probing was observed in 42 implants (35.29%) with a significant higher risk observed in presence of gingival recession, thin peri-implant gingival biotype, duration of implant placement, smokers, and male patients.

    CONCLUSION: Peri-implant bleeding on probing was associated with site specific, implant, and patient level factors.

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