The outbreak of novel coronavirus disease 2019 (COVID-19) has been declared a Public
Health Emergency of International Concern by the World Health Organization. The incidence
of this pandemic continues to rise, with 40,665,438 confirmed cases and 1,121,843 deaths
worldwide by 21 October 2020. During this public health crisis, healthcare workers are at the
frontline of the COVID-19 outbreak response, and as such are at risk of being infected and
developing job burnout while in the line of duty. This study reviews the history of COVID-19
outbreak, infection control measures in hospitals during COVID-19 outbreak, healthcare
workers’ risk of infection and other health effects from battling COVID-19, and challenges and
recommendations for protecting healthcare workers during this pandemic. At present,
healthcare workers are every country’s most valuable resources, and their safety must thus
be ensured. Strong medical leadership, clear pandemic planning, policies and protocols,
continuous educational training, adequate provision of personal protective equipment,
psychological support, and the provision of food, rest, and family support for healthcare
workers would augment a climate of safety in the workplace, ensure their wellbeing, and
improve their capacity to battle this ongoing pandemic.