Displaying publications 161 - 180 of 215 in total

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  1. Gam LH
    World J Exp Med, 2012 Oct 20;2(5):86-91.
    PMID: 24520539 DOI: 10.5493/wjem.v2.i5.86
    Breast cancer is a healthcare concern of women worldwide. Despite procedures being available for diagnosis, prognosis and treatment of breast cancer, researchers are working intensively on the disease in order to improve the life quality of breast cancer patients. At present, there is no single treatment known to bring a definite cure for breast cancer. One of the possible solutions for combating breast cancer is through identification of reliable protein biomarkers that can be effectively used for early detection, prognosis and treatments of the cancer. Therefore, the task of identification of biomarkers for breast cancer has become the focus of many researchers worldwide.
    Matched MeSH terms: Research Personnel
  2. Fadel C, Milanova A, Suran J, Sitovs A, Kim TW, Bello A, et al.
    J Vet Pharmacol Ther, 2024 Jul;47(4):239-251.
    PMID: 38654516 DOI: 10.1111/jvp.13448
    In recent years, especially since the COVID-19 pandemic, the number of predatory journals has increased significantly. Predatory journals exploit the "open-access model" by engaging in deceptive practices such as charging high publication fees without providing the expected quality and performing insufficient or no peer review. Such behaviors undermine the integrity of scientific research and can result in researchers having trouble identifying reputable publication opportunities, particularly early-career researchers who struggle to understand and establish the correct criteria for publication in reputable journals. Publishing in journals that do not fully cover the criteria for scientific publication is also an ethical issue. This review aimed to describe the characteristics of predatory journals, differentiate between reliable and predatory journals, investigate the reasons that lead researchers to publish in predatory journals, evaluate the negative impact of predatory publications on the scientific community, and explore future perspectives. The authors also provide some considerations for researchers (particularly early-career researchers) when selecting journals for publication, explaining the role of metrics, databases, and artificial intelligence in manuscript preparation, with a specific focus on and relevance to publication in veterinary medicine.
    Matched MeSH terms: Research Personnel
  3. Arifin WN, Zahiruddin WM
    Malays J Med Sci, 2017 Oct;24(5):101-105.
    PMID: 29386977 MyJurnal DOI: 10.21315/mjms2017.24.5.11
    Animal research plays an important role in the pre-clinical phase of clinical trials. In animal studies, the power analysis approach to sample size calculation is recommended. Whenever it is not possible to assume the standard deviation and the effect size, an alternative to the power analysis approach is the 'resource equation' approach, which sets the acceptable range of the error degrees of freedom (DF) in an analysis of variance (ANOVA). The aim of this article is to guide researchers in calculating the minimum and maximum numbers of animals required in animal research by reformulating the error DF formulas.
    Matched MeSH terms: Research Personnel
  4. Tunnecliff J, Ilic D, Morgan P, Keating J, Gaida JE, Clearihan L, et al.
    J Med Internet Res, 2015;17(5):e119.
    PMID: 25995192 DOI: 10.2196/jmir.4347
    BACKGROUND: Establishing and promoting connections between health researchers and health professional clinicians may help translate research evidence to clinical practice. Social media may have the capacity to enhance these connections.
    OBJECTIVE: The aim of this study was to explore health researchers' and clinicians' current use of social media and their beliefs and attitudes towards the use of social media for communicating research evidence.
    METHODS: This study used a mixed-methods approach to obtain qualitative and quantitative data. Participation was open to health researchers and clinicians. Data regarding demographic details, current use of social media, and beliefs and attitudes towards the use of social media for professional purposes were obtained through an anonymous Web-based survey. The survey was distributed via email to research centers, educational and clinical institutions, and health professional associations in Australia, India, and Malaysia. Consenting participants were stratified by country and role and selected at random for semistructured telephone interviews to explore themes arising from the survey.
    RESULTS: A total of 856 participants completed the questionnaire with 125 participants declining to participate, resulting in a response rate of 87.3%. 69 interviews were conducted with participants from Australia, India, and Malaysia. Social media was used for recreation by 89.2% (749/840) of participants and for professional purposes by 80.0% (682/852) of participants. Significant associations were found between frequency of professional social media use and age, gender, country of residence, and graduate status. Over a quarter (26.9%, 229/852) of participants used social media for obtaining research evidence, and 15.0% (128/852) of participants used social media for disseminating research evidence. Most participants (95.9%, 810/845) felt there was a role for social media in disseminating or obtaining research evidence. Over half of the participants (449/842, 53.3%) felt they had a need for training in the use of social media for professional development. A key barrier to the professional use of social media was concerns regarding trustworthiness of information.
    CONCLUSIONS: A large majority of health researchers and clinicians use social media in recreational and professional contexts. Social media is less frequently used for communication of research evidence. Training in the use of social media for professional development and methods to improve the trustworthiness of information obtained via social media may enhance the utility of social media for communicating research evidence. Future studies should investigate the efficacy of social media in translating research evidence to clinical practice.
    KEYWORDS: communication; eLearning; evidence-based medicine; social media
    Matched MeSH terms: Research Personnel*
  5. Dalton R
    Nature, 2004 Feb 12;427(6975):576.
    PMID: 14961086
    Matched MeSH terms: Research Personnel/economics*
  6. Chow WS
    Photosynth Res, 2021 Aug;149(1-2):5-24.
    PMID: 33543372 DOI: 10.1007/s11120-021-00818-2
    Despite my humble beginnings in rural China, I had the good fortune of advancing my career and joining an international community of photosynthesis researchers to work on the 'light reactions' that are a fundamental process in Nature. Along with supervisors, mentors, colleagues, students and lab assistants, I worked on ionic redistributions across the photosynthetic membrane in response to illumination, photophosphorylation, forces that regulate the stacking of photosynthetic membranes, the composition of components of the photosynthetic apparatus during acclimation to the light environment, and the failure of the photosynthetic machinery to acclimate to too much light or even to cope with moderate light due to inevitable photodamage. These fascinating underlying mechanisms were investigated in vitro and in vivo. My career path, with its ups and downs, was never secure, but the reward of knowing a little more of the secret of Nature offset the job uncertainty.
    Matched MeSH terms: Research Personnel/history*
  7. Olesen AP, Amin L, Mahadi Z
    Sci Eng Ethics, 2018 12;24(6):1755-1776.
    PMID: 29249021 DOI: 10.1007/s11948-017-9997-9
    Published data and studies on research misconduct, which focuses on researchers in Malaysia, is still lacking, therefore, we decided that this was an area for investigation. This study provides qualitative results for the examined issues through series of in-depth interviews with 21 researchers and lecturers in various universities in Malaysia. The aims of this study were to investigate the researchers' opinions and perceptions regarding what they considered to be research misconduct, their experience with such misconduct, and the factors that contribute to research misconduct. Our findings suggest that the most common research misconducts that are currently being witnessed in Malaysian universities are plagiarism and authorship disputes, however, researchers seldom report incidents of research misconduct because it takes too much time, effort and work to report them, and some are just afraid of repercussions when they do report it. This suggests possible loopholes in the monitoring system, which may allow some researchers to bypass it and engage in misconduct. This study also highlights the structural and individual factors as the most influential factors when it comes to research misconduct besides organizational, situational and cultural factors. Finally, this study highlights the concerns of all participants regarding the 'publish or perish' pressure that they believe would lead to a hostile working environment, thus enhancing research misconduct, as researchers tend to think about their own performance rather than that of whole team or faculty. Consequently this weakens the interpersonal relationships among researchers, which may compromise the teaching and supervision of junior researchers and research students.
    Matched MeSH terms: Research Personnel/ethics*
  8. Ayodele FO, Yao L, Haron H
    Sci Eng Ethics, 2019 04;25(2):357-382.
    PMID: 29441445 DOI: 10.1007/s11948-017-9941-z
    In the management academic research, academic advancement, job security, and the securing of research funds at one's university are judged mainly by one's output of publications in high impact journals. With bogus resumes filled with published journal articles, universities and other allied institutions are keen to recruit or sustain the appointment of such academics. This often places undue pressure on aspiring academics and on those already recruited to engage in research misconduct which often leads to research integrity. This structured review focuses on the ethics and integrity of management research through an analysis of retracted articles published from 2005 to 2016. The study employs a structured literature review methodology whereby retracted articles published between 2005 and 2016 in the field of management science were found using Crossref and Google Scholar. The searched articles were then streamlined by selecting articles based on their relevance and content in accordance with the inclusion criteria. Based on the analysed retracted articles, the study shows evidence of ethical misconduct among researchers of management science. Such misconduct includes data falsification, the duplication of submitted articles, plagiarism, data irregularity and incomplete citation practices. Interestingly, the analysed results indicate that the field of knowledge management includes the highest number of retracted articles, with plagiarism constituting the most significant ethical issue. Furthermore, the findings of this study show that ethical misconduct is not restricted to a particular geographic location; it occurs in numerous countries. In turn, avenues of further study on research misconduct in management research are proposed.
    Matched MeSH terms: Research Personnel/ethics*
  9. Isa NM, Hj Safian Shuri MF
    Sci Eng Ethics, 2018 02;24(1):109-127.
    PMID: 28281149 DOI: 10.1007/s11948-017-9887-1
    Advancements in science and technology have not only brought hope to humankind to produce disease-free offspring, but also offer possibilities to genetically enhance the next generation's traits and capacities. Human genetic enhancement, however, raises complex ethical questions, such as to what extent should it be allowed? It has been a great challenge for humankind to develop robust ethical guidelines for human genetic enhancement that address both public concerns and needs. We believe that research about public concerns is necessary prior to developing such guidelines, yet the issues have not been thoroughly investigated in many countries, including Malaysia. Since the novel often functions as a medium for the public to express their concerns, this paper explores ethical concerns about human genetic enhancement expressed in four Malay science fiction novels namely Klon, Leksikon Ledang, Transgenesis Bisikan Rimba and Transgenik Sifar. Religion has a strong influence on the worldview of the Malays therefore some concerns such as playing God are obviously religious. Association of the negative image of scientists as well as the private research companies with the research on human genetic enhancement reflects the authors' concerns about the main motivations for conducting such research and the extent to which such research will benefit society.
    Matched MeSH terms: Research Personnel/ethics
  10. Nehzat F, Huda BZ, Tajuddin SH
    PMID: 24968690
    Job Content Questionnaire (JCQ) has been proven a reliable and valid instrument to assess job stress in many countries and among various occupations. In Malaysia, both English and Malay versions of the JCQ have been administered to automotive workers, schoolteachers, and office workers. This study assessed the reliability and validity of the instrument with research laboratory staff in a university. A cross sectional study was conducted among 258 research laboratory staff in Universiti Putra Malaysia (UPM). Malaysian laboratory staff who have worked for at least one year were randomly selected from nine faculties and institutes in the university that have research laboratory. A self-administered English and Malay version of Job Content Questionnaire (JCQ) was used. Three major scales of JCQ: decision latitude, psychological job demands, and social support were assessed. Cronbach's alpha coefficients of two scales were acceptable, decision latitude and psychological job demands (0.70 and 0.72, respectively), while Cronbach's alpha coefficient for social support (0.86) was good. Exploratory factor analysis showed five factors that correspond closely to the theoretical construct of the questionnaire. The results of this research suggest that the JCQ is reliable and valid for examining psychosocial work situations and job strain among research laboratory staff. Further studies should be done for confirmative results, and further evaluation is needed on the decision authority subscale for this occupation.
    Matched MeSH terms: Research Personnel/psychology*
  11. Nurul Ain, K.B., Mahanem, M.N., Irfan, Y.
    Medicine & Health, 2018;13(2):20-35.
    MyJurnal
    Population explosion is one of the global issues of concern. The increasing number of individuals could result in negative impact on social and economy. To overcome this problem, convenient and safe modern contraception was introduced. However, recently many researchers have conducted studies on the effectiveness of medicinal plants as contraceptive agents on human and animal models. Therefore, the studies of herbal and modern contraceptives were summarized in this review article. A total of 66 relevant articles were documented having information regarding the modern and herbal contraceptives. All contraceptives are highly effective provided they are used consistently and in the proper way. Contraception is important as it could prevent diseases and infections caused by sexual intercourse and prevent unintended pregnancy. Therefore, this review is an attempt to summarize the potential of medicinal plants as contraceptive agents and the modern contraceptive methods used as birth control in males and females.
    Matched MeSH terms: Research Personnel
  12. Ahmad NJ, Althemery AU, Haseeb A, Yusuf RF, Hassali AA, Khan AH
    J Pharm Bioallied Sci, 2020 01 29;12(1):11-15.
    PMID: 32801595 DOI: 10.4103/jpbs.JPBS_186_19
    Introduction: The implementation of antibiotic stewardship programs (ASPs) can improve the treatment of infections and can decrease the adverse events that result from antibiotics use. In the last decades, there is an increasing interest of the researchers in the implementation of ASPs.

    Materials and Methods: The articles published in different journals were retrieved by searching many research databases such as Cochrane library, Europe PMC, PubMed, and Web of Science; we searched these databases for all published articles till November 2018.

    Results and Discussion: The searching results using Cochrane library showed an increase in the number of randomized clinical trials that related to the keyword of "antimicrobial stewardship" specially in the last 5 years. Using Europe PMC, we found 6178 results. From these results, there are 3874 free full texts. In addition, there are 2132 original articles in PubMed and by searching Web of Science database till November 8 there are 3085 results. These results show that the number of trusted published articles was increased continuously; this shows the increasing interest of the researchers in ASPs. These researches will help health-care providers to use antibiotics appropriately and to overcome the barriers of implementing ASPs.

    Conclusion: The results of this study show that the researchers had high levels of interest in participating in research activities related to the appropriate use on antibiotics and the implementation of antimicrobial stewardship programs.

    Matched MeSH terms: Research Personnel
  13. Sooryanarayana R, Wong NI, Ahmad NA, Razak MAA, Yusoff MFM, Chan YY, et al.
    Geriatr Gerontol Int, 2020 Dec;20 Suppl 2:7-15.
    PMID: 33370855 DOI: 10.1111/ggi.14094
    AIM: This article describes the methodology of the 2018 Malaysian National Health and Morbidity Survey, and provides an overview of the sociodemographic details of the respondents and key findings on the health of older adults.

    METHODS: The survey included 3977 community-dwelling respondents, aged ≥60 years across Malaysia. Two-stage stratified random sampling with selection of enumeration blocks from both urban and rural areas ensured the findings were representative of the Malaysian older population.

    RESULTS: Complex sampling analyses ensured that findings on various geriatric syndromes, non-communicable diseases, nutritional status, functional status, social well-being and quality of life are representative of the Malaysian older population. Among the limitations are that the composition of older persons varied slightly from the general older population.

    CONCLUSIONS: This article presents the methodology of the survey, and a baseline of the major health issues for older persons in Malaysia to provide clear guidance to researchers, program managers and policymakers to fully utilize the data from the Malaysian National Health and Morbidity Survey toward achieving healthy aging. The findings might stimulate more research on the health problems faced by older people to provide inputs for policymaking and program implementation. Geriatr Gerontol Int 2020; 20: 7-15.

    Matched MeSH terms: Research Personnel
  14. Chen LL, Mat Ludin AF, Shahar S, Manaf ZA, Tohit NM
    Syst Rev, 2020 Nov 23;9(1):265.
    PMID: 33228765 DOI: 10.1186/s13643-020-01517-0
    BACKGROUND: The prevalence of type-2 diabetes mellitus (T2DM) has been increasing globally. Without proper management, T2DM can develop into serious complications and even death. Diet modification is one of the most effective tools in managing T2DM at the early stage, but it requires knowledge and compliance from the patients. Thus, meal replacement (MR) has gained its popularity as a tool for diet modification to improve glycemic control and also reducing weight in T2DM patients. There are several existing meal replacement studies but not much is known on the general scope and effect of these existing MRs. Hence, this review is aimed to provide an overview of the existing evidences regarding the application of meal replacement on T2DM patients and identify the gaps or limitations in the studies.

    METHODOLOGY: The scoping review will be carried out in six stages: (1) identifying the research question, (2) identifying relevant studies through electronic databases (i.e., PubMed, Scopus, Cochrane Reviews, Google Scholar, EBSCOHOST, Science Direct) and also gray literature, and (3) selection of studies to be included based on inclusion criteria. Search and initial screening of studies to be included will be conducted by two independent reviewers. Discrepancies will then be solved through discussion with other reviewers; (4) charting and categorizing extracted data in a pretested data extraction form; (5) collating, summarizing, and reporting the results; and lastly, (6) conducting consultation with stakeholders and experts in diabetes.

    DISCUSSION: This scoping review protocol is aimed to provide a framework enabling us to map and summarize the findings from existing studies involving meal replacement. It will help researchers to identify the research gap and provide recommendations for future meal replacement studies. The results from this scoping review will be useful to various stakeholders in healthcare. It is also part of a research project in which the information obtained will be utilized in a clinical trial of a developed meal replacement plan. Dissemination of knowledge will also be done through presentations at related scientific conferences.

    Matched MeSH terms: Research Personnel
  15. Kabir, M.U., Abdulkarim, S.M., Son, R., Azizah, A.H., Saari, N.B.
    MyJurnal
    Phytochemicals belonging to the group’s phenols, terpenes, betalains, organosulfides, indoles and protein inhibitors are important components in fruits, vegetables, legumes, whole grains and nuts that have health promoting benefits and a variety of applications in food and pharmaceutical industries. Initially only a few of these important phytochemicals are produced commercially by chemical synthesis. However, recent developments in the field of biotechnology have provided metabolic engineering strategies that use microorganisms as cell factories for high production of these products. This review will discuss the general biosynthetic pathways, metabolic engineering and optimization strategies of functional phytochemicals that have received a lot of attention from investigators.
    Matched MeSH terms: Research Personnel
  16. Mohd Yasin MH, Sahari N, Nasution AH
    MyJurnal
    A literate and numerate population is the goal of any modern industrialized society. Literacy and mathematics skills carry the means by which children are equipped for the education processes on which their future will depend. Deaf and hard of hearing students' reading and mathematics skills are lower than that of others due to their inability. Before enhancing their literacy and mathematics skills, their standard of literacy and mathematics skills should first be identified. For this reason, the Malaysian Ministry of Education initiated the Literacy and Numeracy Screening (LINUS) program in 2009. However, problems arose in the assessment method of LINUS screening for these students since the LINUS screening method does not accommodate these students' situation and needs. Therefore, the researchers introduced internet-based Literacy and Mathematics Assessment (iLiMA) prototype that can overcome those problems. In the iLiMA prototype, sign language instruction video is used to standardize the assessment method in order to ensure that non-bias assessment could be established. The methodology used to develop this system is the Evolutionary Process Model - Prototype. The iLiMA prototype usability was assessed with the Computer System Usability Questionnaire (CSUQ) and conducted by using web-based survey method. The results indicate that the iLiMA prototype is usable and teachers are satisfied with it. Finally, the iLiMA prototype which had the potential to accommodate deaf and hard of hearing students to get a standardized and non-bias literacy and mathematics assessment was developed.
    Matched MeSH terms: Research Personnel
  17. Mohd Jailani Mohd Nor, Rabiah Ahmad
    MyJurnal
    In Malaysia, all sectors are currently gearing themselves in supporting the initiatives of becoming a developed nation by the year 2020. The most important element in ensuring the success of this mission is to provide critical mass of knowledge workers to champion this cause. As such the Ministry of Higher Education Malaysia (MOHE) has established the National Higher Education Strategic Plan (NHESP), comprising seven thrusts which are very crucial in providing the much needed human capital and eco-system for this agenda. The essence of NHESP is also in line with other initiatives established by the government of Malaysia such as the National Key Results Area (NKRA) and the Government Transformation Plan (GTP). In fact MOHE has developed a systematic working model for the academia to play their role actively in driving the agenda of transforming Malaysia into a developed nation. The workforce required to spearhead the agenda for an innovation-led economy can be categorized into five different groups namely: Discoverers; Innovators; Inventors; Transformers; and Technopreneurs. It is very crucial for MOHE to develop and implement a comprehensive programme for producing a new breed of researchers that can contribute in translating government policies into a reality. This article presents the challenges and success stories in reforming the landscape of Research and Development in Malaysian universities and research institutions. The establishment of NHESP has made it possible for MOHE to systematically establish comprehensive guidelines for the management of research grants, standard for research conduct, instrument to measure research performance, and standardized reporting of research and innovation output. This new approach in the management of research at the ministry level has created positive ramifications for universities, research institutions, research management centres, and research leaders. During the first five-year cycle (2006-2010) of these research initiatives, and now into the second phase (2011-2015), positive results and outcomes have started to emerge. These results include increased in generation of articles on research findings published in reputable journals worldwide. Currently, Malaysia is recognized for achieving the world's fastest growth rate in number of journal publications. In addition, increased in number of postgraduate students, commercialization of R&D products and the establishment of Higher Institutions Centres of Excellence (HiCOE) contribute towards producing a new breed of great researchers in Malaysia. A continuing positive trend indicates that this phenomenal growth will be sustained for the next few years.
    Matched MeSH terms: Research Personnel
  18. Azhari Muhammad Syam, Robiah Yunus, Tinia Idaty Mohd. Ghazi, Choong, Thomas Shean Yaw
    MyJurnal
    Research on the use of Jatropha curcas triglycerides as biodiesel feedstock has received worldwide attention due to its inherent characteristics. Unlike palm oil, J. curcas oil is not edible, and thus, it will not disturb the food supply. However, to the researchers' experiences with the synthesis of J. curcas, oil-based biodiesel has shown that the fuel characteristics depend largely on the type of alcohol used as the excess reactants. Transesterification reaction is chosen for this process with sodium methoxide as the catalyst. Comparison studies on the yield of esters using methanol and ethanol, as well as the impacts on the reaction rate are discussed. The effects of reaction time and molar ratio on the reaction conversion are also examined. The determination of reaction yield is based on the conversion of triglycerides into alkyl esters as the main product. The findings are described as follows: the highest percentage yield of product is attained at 96% for methanol as an excess reactant, and this is 90% when ethanol is used. The optimum conditions of parameters are achieved at 6:1 molar ratio of alcohol to triglycerides, 50 min of reaction time and reaction temperature of 65°C for methanol and 75°C for ethanol. The biodiesel properties of both ester fuels were determined according to the existing standards for biodiesel and compared to the characteristics of diesel fuel.
    Matched MeSH terms: Research Personnel
  19. Wan Norlida Ibrahim, Syed Aljunid, Aniza Ismail
    MyJurnal
    Increasing prevalence of chronic diseases is a major contributor for rapid rise in healthcare cost in developing countries since the last decade. It was estimated that around 54% of deaths in developing countries are due to chronic non-communicable diseases which is predicted to rise by 65% by 2030. Diabetes mellitus is among the most prevalent chronic diseases suffered by more than 180 million people worldwide. By 2030 it is estimated that around 400 million people in the world will be afflicted with diabetes. Annual deaths attributable to diabetes are probably as high as 3 million with more than 80% occur in developing countries. India, China and Indonesia are three countries in the Asian region with most number of people with diabetes. The total number of cases in these three countries is expected to increase more than double from 61 million in 2000 to 163 million in 2030. China and India will suffer cumulative GDP loss of 13.8% and 16.7% respectively, over the next ten year period. Assessing economic burden of diabetes is a challenging task for researchers because identification of direct and indirect cost of the disease is often complex since patients with diabetes also suffers from other complications and co-morbidities. In conclusion, the heavy economic burden of diabetes pose major challenges to health policy makers in developing countries to assess the current approach in managing this chronic disease. Serious efforts should be made on focusing and up-scaling activities on health promotion and prevention of diabetes so that to provide a more cost-effective solution to this condition with huge and increasing economic loss.
    Matched MeSH terms: Research Personnel
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