Introduction: Knowledge, attitude as well as adoption of pharmacogenomics in clinical practice among the pharmacists and physicians in Malaysia have not been reported. This cross-sectional study explores various facets of the two professions as related to pharmacogenomics to determine the need and preferred method to improve education among them. This study also aims to identify the current state of pharmacogenomics practice in Malaysia to help identify barrier and solution to reap advantages from pharmacogenomics practices. Methods: A questionnaire consisting of 38 questions in five parts was adopted and validated. It explores the respondents’ characteristics, attitude, knowledge, adoption and education. It was distributed online to 1500 pharmacists and physicians over five months. Results: Pharmacists differed from the physicians in terms of attitude, knowledge, adoption and education. Overall, adoption rate of pharmacogenomics was found to be low but its anticipation for future adoption is high, and benefits were reported by healthcare professionals who have used the test in a clinical setting. Majority of respondents had poor to fair knowledge and nearly half have had no prior formal teaching on pharmacogenomics. Interest in the education is very high, and most of them preferred to learn pharmacogenomics via continuous professional education programs. Conclusion: Pharmacogenomics is a field that promises many benefits, but to reap these benefits require its implementation in clinical setting. Pharmacists and physicians need to be equipped with adequate knowledge and positive attitude towards pharmacogenomics.
HbA1c is an established index of glycaemic control and correlates strongly with risk of chronic diabetic complications. However, the accuracy of HbA1c measurement can be affected by many factors, among which is the presence of haemoglobin (Hb) variants. The aim of the study was to determine the percentage of Hb variant detected during HbA1c monitoring in Hospital Kuala Lumpur. The study also analysed non-reportable HbA1c results in the presence of Hb variants. A cross-sectional study using retrospective data of HbA1c results over five months’ period was analysed on Biorad Variant II Turbo, a high performance liquid chromatography (HPLC) assay. The Hb variants were grouped either as HbS, HbC, others (Hb variant apart from HbS or C), and a combination of HbS or C with Others. A total of 11,904 patients were included. Only 2.3% (273) had Hb variants; HbS trait (10.3%), others (89%), and the combination of HbS trait with others (0.7%). No patient with HbC variant or its combination was found. Only 2.2% of those with Hb variant had non-reportable HbA1c. Although the percentage of Hb variants detected during HbA1c analysis and non-reportable HbA1c results were low, their presence should be noted.
Background: The International Medical University (IMU) has an outcome-based curriculum defined by eight major curriculum outcome domains.The attributes, qualities and competencies expected of a health care professional form the basis for these outcome domains. Community service is an effective curriculum delivery tool widely practised by medical universities around the world. We present the results of a survey among IMU students to explore the effectiveness of community service as a curriculum delivery tool in enabling activities defined within the major curriculum outcome domains of IMU.
Methods: A self-administered 6-point Likert scale questionnaire was used to survey student participants of 20 community service events held in a rural village between 2007–2012. The survey tool included questions on demographic data as well as the perception of the students on whether participation in the events enabled them to experience activities defined under the eight major curriculum outcome domains of IMU.The one sample Student t-test was used to test for statistical significance while regression analysis was done to look for significant predictors.
Results: A total of 255 students were surveyed, of which 229 (90.5%) were medical students while the rest were nursing students. Most of the students were in the 3rd (48.2%) and 4th (43.8%) year of their studies and have completed the surgery, internal medicine and family medicine posting. Six out of the 8 curriculum outcomes domains were achieved through participation in the community service programme.
Conclusion: Community service is an effective curriculum delivery tool for the outcome-based curriculum of IMU where activities defined in six out of eight outcome domains were achieved.
Background: This cross sectional study was done to identify the areas of lack of knowledge, practice and awareness of students about the effective use of personal protective equipment (PPE).
Methods: A total of 40 students were selected when they were posted to the accident and emergency unit (A&E) in Seremban Hospital; all of them answered a questionnaire and were observed unaware on the effective use of PPE in the A&E.
Results: We found that 17.5% of students were unaware of the right technique of removing the gloves after a procedure and 25% of students were unaware of safety of hand washing. During invasive procedures, 12.5 % of students did not wash their hands before invasive procedures, 65% did not wear aprons and 57.5% did not wear masks. During non- invasive procedures more than 25% of students did not wash hands before or after the procedures.
Conclusion: There is still significant lack of knowledge in students about the effective use of PPE that needs to be addressed.
Keywords: PPE, Personal protective equipment, effective practice of PPE, A&E
Objective: The objective of this study was to assess the relationship between stress score and body mass index (BMI) of students of Science in Kuala Lumpur. Methods: A cross-sectional study was carried out among 126 students. Data about stress score were collected using a questionnaire, the Student-Life Stress Inventory (SLSI) Data about BMI were calculated from height and weight of the respondents. Results: A total of 117 (92.85%) out of 126 students had responded. The mean difference of stress score among first, second and third year students were 87.6 ± 17.0, 83.4 ± 16.9 and 86.7 ± 15.4 respectively. The mean difference of stress scores between the Bumiputra and non-Bumiputra students were 87.9 ± 16.5 and 83.2 ± 15.9 .The mean of body mass Index(BMI) between first, second and third year students were 21.0 ± 3.5, 20.3 ± 2.7 and 21.8 ± 4.3 respectively. Conclusions: This study showed that the stress level is higher in first year, female and bumiputra student. There was no significant relationship between stress score and BMI.
Objective: Postgraduate medical training has always been regarded as a highly stressful environment to students. This article described an initial finding on prevalence and sources of stress among postgraduate students. Method: This is a cross-sectional study conducted on postgraduate students in the School of Medical Sciences, Universiti Sains Malaysia. Sample size as calculated for this preliminary study was 38 and convenient sampling method was applied. The 12 items General Health Questionnaire (GHQ-12) and Postgraduate Stressors Questionnaire (PSQ) were administered during a workshop involving postgraduate students. Data was analysed using SPSS version 12. Results: Thirty three participants participated in this study. This study found that the prevalence of distressed postgraduate students was 36.4%. The top ten stressors were tests and examinations, large amount of content to be learnt, time pressure to meet deadlines, doing work beyond
ability, work overload, unfair assessment by superior, fears of making mistakes that can lead to serious consequences, doing work that mentally straining, work demands affect my personal and home life, and lack of time to review what have been learnt. Conclusion: This study found that there was a high prevalence of distressed postgraduate students. It also found that the major stressors were related to academic and performance pressure.
There is a need to develop an Occupational Safety and Health Management System (OSHMS) Critical Success Factors (CSF) Monitoring among gas contractor in Malaysia. Critical Success Factors (CSF) can be used for future implementation, adaptation and practice for gas contractor work for both by clients and contractors in Malaysia. The main purpose of CSF implementation is to reduce the number of accident related with Occupational Safety and Health (OSH). The need for CSF is due to the requirement by law and standard that require companies to establish an arrangement related to the identified OSH risks. The objective of this study is to assess the established of OSHMS among gas contractor in Peninsular Malaysia and to identify the CSF imposed by these industries. A cross sectional study for eighty gas contractor companies using established questionnaire has been done. All data consolidated in order to determine the OSHMS and it CSF among gas contractor in Peninsular Malaysia that has registered with Department of Occupational Safety and Health. Established questionnaire are based on OSHMS MS 1722:2011 elements requirement No 1: Policy, No 2: Organizing, No 3: Planning and Implementation, No 4: Evaluation and No 5: Action for Improvement as parameters to come out with organization means and Z-scores. Descriptive statistic showed that element mean (standard deviation) score for policy is 75(6.6), for Organizing is 63(5.2), for Planning and Implementation is 59(9.4), for Evaluation is 66(5.1) and Action for Improvement is 63(1.3). Percentage of company that complies with the main element for Policy is 15%, for Organizing is 8.8%, for Planning and Implementation is 11.3%, for evaluation is 11.3% and for Action for improvement is 13.8%. Percentage of companies that partially comply with Policy element is distributed between 61.0% to 85.0% which is 76.3 %, for Organizing score is mainly distributed between 46.0% to 60.0% which is 62.5%, for planning and Implementation score for 80 companies distributed mainly in group score between 46.0 to 60.0% which is 56.3 %, for Evaluation the partially comply score is distributed in group score between 61.0% to 85.5% which is 41 % and for Action for Improvement partially comply score, the distribution is mainly distribute in range of 61.0% to 85.0% which is 62.5 %. Z-score for element policy is five points from policy mean, for organizing Z-score is three points from Organizing mean, for Planning and Implementation the Z-score is three points from Planning and Implementation mean, for Evaluation the Z-score is three points from evaluation mean and for Action for improvement Z-score is two to three points from Action for Improvement mean. Percentage of compliance with OSHMS MS 1722:2011 elements by gas contractors in almost main element and sub element are still low and can be further improved by focusing on all company element score for continual improvement of OSH elements compliances.
Homocysteine could be a mechanism that underlies the effects of lead on cardiovascular system. This study aims to identify the relationship between lead exposure and homocysteine levels among workers. A comparative cross-sectional study was carried out on 80 workers of an automotive components manufacturing factory; that comprised of 40 exposed workers and 40 non-exposed workers. Blood samples of respondents were taken by fingerprick. The blood samples were analyzed for blood lead concentration by using Atomic Absorption Spectrometry Graphite Furnace Model GBC 908AA. Besides that, ELISA Kit was used to show the homocysteine level among the respondents. Questionnaires were used to obtain demography information of respondents. Results from the statistical analysis showed that the mean blood lead concentration for exposed respondents was 5.53±4.74 μg/dL and 3.53±2.81 μg/dL for the comparative respondents. Mann-Whitney U test showed that there was no significance difference between the mean blood lead concentration of the exposed and comparative group (z=-1.178; p=0.075). The blood lead concentration ranged 0.68-17.95 among the exposed group and with a range of 0.084-11.96 for the comparative group. The mean homocysteine level (μmol/L) was 32.48±2.481μmol/L for the exposed group and 16.50±4.0960 μmol/L for the comparative group. There was a significant difference in homocysteine level (μmol/L) between the exposed (32.48±2.481) and comparative (16.50±4.0959) groups (z = -7.699, p
Fogging activity has become one of the important methods in tackling dengue outbreaks nowadays. Despite this, it is an occupation that has known hazards namely noise and pesticides which can affect the body organs. Based on this knowledge, a cross sectional study was conducted to determine the association between hearing impairment and serum cholinesterase level among foggers from five randomly selected Health District Offices in Selangor. A total of 200 workers comprising of 100 workers exposed to fogging activity and another 100 workers not exposed were randomly selected for this study. Data was obtained through self administered questionnaire, audiometric testing and serum cholinesterase level measurement. The overall prevalence of hearing impairment was 16% with foggers having significant higher prevalence (24%) compared to the non foggers (8%) (χ2=9.52, p=0.002). Measurement of serum cholinesterase showed that exposed workers had lower level compared to the non exposed group. Similarly, those who have hearing impairment had also lower serum cholinesterase level although it was not statistically different. Among all studied factors, age and duration of exposure to fogging activities were statistically different with hearing impairment (p
Background: A cross-sectional study on work-related stressors among nurses in a public teaching hospital had also attempted to explore functions of coping strategies in determining stress.
Materials and Methods: A structured bilingual questionnaire (English-Malay) on symptoms and sources of stress, and coping style measure was disseminated to medical and surgical nurses working in a teaching hospital in Kuala Lumpur. Socio demographic information and stress management methods were inquired. Frequency in workplace stressors were assessed using Nursing Stress Scale. Stress symptoms and home-life stressors were evaluated using Personal Stress Inventory. Measurement of coping strategies was performed using Coping Orientation for Problems Experienced questionnaire.
Results: A total of 181 questionnaires were disseminated and 151 (83.4%) were satisfactorily completed by nurses. It was found that the prevalence of work-related stress among medical and surgical nurses was 49.3% (N=74/150). Analysis of dichotomized outcome (between Stress and No stress group) illustrated high workload (t-value=4.122; p
Objective: this study was carried out to evaluate the relationship between smoking and periodontal status in a selected Malaysian population. The sample for this cross-sectional study involved 39 subjects who were smokers. Each subject was required to answer the guided questionnaire followed by clinical examination. The questionnaires had 11 questions and were set in English and Bahasa Melayu. Basically, the questionnaire consisted of 3 sections: socio-demographic data, smoking status and subject's knowledge on periodontal health. The clinical parameters used in this study were: Community Periodontal Index, Visible Plaque score, Gingival Bleeding Index and Calculus Surface Index. Results showed that out of 39 subjects, 28 subjects (71.8%) were current smokers, followed by 6 subjects (15.4%) and 5 subjects (12.8%) who were former and who never smoked respectively. From the 216 sextants examined, 42 sextants (19.4%) were healthy gingival, 127 sextants (58.8%) suffered from gingivitis and 47 (21.8%) sextants suffered from periodontitis. There were positive relationships between smoking and periodontal status.
A cross sectional survey was conducted in Kampung Datuk Kerarnat, an urbanized residential area in Kuala Lumpur from August to November ZOO5 to assess knowledge, attitude and preventive practices on dengue among its residents. A two stage sampling strategy was used to select survey household. An adult aged at least 21 years old was identified from each selected household and interviewed using a standardized questionnaire. Data was collected on demographics, dengue related KAP and house-types. Knowledge, attitude and practice were assessed using a scoring system. Each appropriate answer was given a point and the points for each section of the questionnaire were totalled. Knowledge was assessed as ‘good' or ‘moderate to poor’ based on arbitrary cut-off point. Out of 133 respondents interviewed, 78.2% were able to identify at least one clinical sign of dengue, 73% knew that dengue fever was caused by the bite of dengue infected Aedes mosquitoes, 71 % correctly identified breeding sites, 69.2% correctly identified the Aedes mosquito and 42% correctly reported biting times ofthe mosquito vector. Overall, knowledge
was categorized as poor, attitude was good and dengue control and prevention practices was moderately poor. There was a weak but significant positive correlation between knowledge and practice (r=0.271, p=0.002) but there was no significant correlation between attitude with practice and between attitude with knowledge (p>0.05) . The results suggested that inspite of good attitude l
on dengue fever, it did not correlate with good practices and good knowledge in dengue prevention. We conclude that there is a need to increase health promotion activities to increase knowledge which forms the basis for preventive practices as part of the strategy to control dengue. Preventive strategies are the only means of controlling the disease.
The objective of this pilot cross-sectional study was to assess effcacy of training dental officers (DO) and nurses (DN) in the Index of Orthodontic Treatment Need (IOTN). A conventional training method of lectures, manual; and md5,0n* exettise was used for bath Lest groups. 30 study models in all grades in the Aesthetic component (AC) and dental health component (DHC) were graded by 27 subjects (13 DO, 14 DN) after training. Results were cnrrlparedfor agreement with an exper; group, Kappa statistic: was used to assess strength in agreement in correct grouping of AC and DHC in the Categorie; gf treatment need, Wilcoxon Rank sum test was used to compare mean kappa and % 0 correct res ames in the test. Spearman rank correlation was used to test association of 11g experience with mean kappa values. There was ‘m0demte’ agreement in correct groupingfor ojjqcers in AC (K=O.5l) and DHC (K`=O.4l); Cmd 'fair’ j‘0'f TluTS€S in AC (K=O.40) and DHC (K:O,34). There was no significant difference between groups. Subjects were better at identifying cases with definite need than little/ borderline need for treatment. There was more inaccurate grading in DHC Gmde+qualifier for both groups (p
A cross»sectional study using self administered questionnaires on sociodemographic and service factors influencing locum practice was undertaken among all Government medical officers in Negeri Sembilan and Malacca for 8 months from 2 7 April 1999 to 9. l January ZOOO. Universally chosen samples were made of 335 Government medical officers from both the 'Public Health Division' and ”Hospital Division' and from 154 who responded, only 147 samples were chosen and analysed in the study. Results revealed that locum were still being practised by 51 .9% of male Government medical officers, 41 .0% of Government medical ofhcers aged less than 30 years, 43.4% of Government medical officers who had served less than 5 years and 55.6% of Government medical officers who had earned nett income less than RM 1 000. Meanwhile, 80.9% of Government medical officers who had earned gross income more than RM 5 OOO did not practice locum during the study. Logistic Regression analysis then revealed that locum practice among Government medical ofhcers can positively be influenced by gender (male) , Malay ethnic, service duration of less than 5 years, practice in the 'Public Health Divisionl and nett income of less than RM 1 OOO (p
Despite the debates of the benefits of continuing mammography screening among elderly women, studies in Malaysia have shown that the prevalence of breast examination declines after age 45 years and for mammogram per se, the prevalence of examination increases until age of 64. This study aims to determine the prevalence of mammogram screening among elderly women in Hulu Langat, Selangor and its relationship with factors such as demographic factors, family history of breast cancer, perceived health status, perceived general psychological factor and lifestyle factors. Data used were from a cross sectional study of health status among community in Hulu Langat area by the Department of Community Health, Universiti Kebangsaan Malaysia carried out from the year 1998 till 2002. However this paper focused on the database involving elderly women age 60 and above. The sample population was 652. The mean (standard deviation) age was 67.17 (5.995). Only 8.3% of the elderly women claimed to ever had mammogram screening done. Hence, the prevalence of mammogram screening is still low among elderly women in Hulu Langat. Having family history of breast cancer (p < 0.001) and perceived positive psychological status (p=0.003) had shown significant associations with mammogram screening among them. It is therefore important for researcher to further look into the reasons behind this and qualitative exploration is highly recommended.
Dengue Fever is a major public health issue in Malaysia. This study aimed to assess knowledge, attitude and practice regarding dengue fever and effectiveness of health education programme among 204 students of Alam Shah Science School, Cheras/Kuala Lumpur. Study design was a cross sectional study followed by an interventional (pre-post) Study. The self-administered questionnaire included questions on sociodemographic factors, knowledge, attitude and practice regarding dengue fever. Majority of respondents were Malays (96.6%), monthly family income more than RM 3000 (64.6%) and lives in urban area (64.6%). There was no significant association between knowledge status and socio-demographic factors (p-value>0.05). Most of the respondents had good knowledge (63.2%) good attitudes (79.9%) regarding dengue fever. However, practices to prevent dengue was poor (74.0%). Only about one-fifth of the respondents (18.2%) believed that dengue fever is a flu-like illness. Knowledge score was significantly increased after health education programme (p value
Objective: The objective of the present study was to determine the prevalence and factors contributing to psychological morbidity among doctors in Sana’a city, Yemen. Methods: A cross sectional study was conducted among 442 Yemeni doctors. The (GHQ12) was used as a measure of psychological morbidity. Sources of job stress were determined using a 37-item scale questionnaire. Results: The prevalence of psychological morbidity was 68.1 %. Gender, age range of 30 – 39 years old, chewing Khat, type of residence and income were significantly associated with psychological morbidity (p
Background : Risk management strategy at the workplace needs two way interactions between employee and employer. Therefore, study on risk perception among workers based on scientific analysis is needed to gain knowledge and understanding on how workers perceived risk at the workplace in order to design risk management strategies more effectively.
Methodology : A cross sectional study was carried out among 628 respondents from 36 medical laboratories in the public and private sector in Klang Valley. Using a self administered questionnaire, respondents were required to perceive risk on 30 hazards which have been identified in the medical laboratory. Each hazard was encoded by using Likert scale 1= not risky, 2= risky but low, 3= moderate risk, 4= high risk and 5= very high risk.
Result : Overall, the study showed that working in the medical laboratory was perceived to of moderate risk. When comparing among ethic groups, the Malays had the highest perception of risk (3.07±0.88) as compared with Indians (3.03±0.88) and the Chinese (2.78±0.90). Employee with higher education and position level perceived low level of risk compared to those with lower education and position level. For those working in different types of laboratories, there are significant difference on risk perception, (p=0.001). Employees who work in government sector perceived higher (3.12±0.93) risk compared to workers in private sector (2.85±0.88). In terms of OSH based knowledge, those with higher level of education and position have a high score knowledge on OSH compared to those have lower education and position level.
Conclusion : This study showed that risk perception among workers in medical laboratory is influenced by socio-demography factor such race, education level, job position and the laboratory where the respondents are working.
OBJECTIVES: The objectives of this study were to assess the general public views and familiarity toward electronic cigarette (e-cigarette) in Kuantan, Malaysia.
METHODOLOGY: A total of 277 Kuantan people were involved in this study. The questionnaire was distributed at random in shops, businesses, and public places in Kuantan. Statistical analysis was performed using SPSS (version 17.0).
RESULTS: From 400 participants, a total number of 277 (160, 57.7% men and 117, 42.4% women) respondents completed the questionnaire. The mean age was 26.89 ± 9.8 years old. The majority of the study participants were male (57.7%), Malay (83.8%), Muslims (83.8%), singles (69%), and employed (75.8%), with about 83 (29.9%) of the respondents were smokers. The prevalence of e-cigarettes smokers was found to be only 1.4% (n = 4). About one-third of the respondents (n = 72, 26%) have tried e-cigarette before. Job status was significantly associated with smoking e-cigarette among the population (P = 0.02). Main factors for a person to start e-cigarette smoking were curiosity (37.5%) and cheaper price (40.8%). Majority of respondents agreed that e-cigarette would not affect health as normal cigarette, and that variety of flavors contribute to better enjoyment (51.6% and 66.7%, respectively).
CONCLUSION: The results of the current study demonstrate that the prevalence of e-cigarettes smoking and its popularity, familiarity, and knowledge are still insufficient among Kuantan population. Further studies should be done to tackle this problem before it getting worse.
KEYWORDS: Electronic-cigarette; Malaysia; experimentation; perception; prevalence
Comment in: Farsalinos KE, Le Houezec J. Electronic cigarette experimentation in the Malaysian city of Kuantan: Was there an association with the smoking status? J Pharm Bioallied Sci. 2016 Oct-Dec;8(4):347-348
House officers who are suffering from stress, anxiety or depression are at risk of harm to themselves, colleagues and even patients, as well as affecting their livelihood. Objective: This
study is aimed to find the prevalence of stress, anxiety and depression among house officers working
in Kota Kinabalu, Sabah. Method: A cross-sectional study was done using a self-administered
questionnaire containing socio-demographic factors and Depression, Anxiety and Stress Scale (DASS)
21. Results: Prevalence of stress, anxiety and depression were 57.1%, 63.7%, and 42.9% respectively. Multiple logistic regression analysis found that house officers who thought of quitting Housemanship was associated with stress (adjusted OR = 3.64, 95% CI: (1.44, 9.20), p = 0.006), and depression (adjusted OR = 8.26, 95% CI: (2.96, 23.02), p < 0.001). House officers who perceives that they are bullied is associated with anxiety (adjusted OR = 4.16, 95% CI: (1.33, 13.07), p = 0.015). Work
experience of the house officers in months have a protective effect to stress (adjusted OR = 0.92, 95%
CI: (0.87, 0.97), p = 0.004), anxiety (adjusted OR = 0.93, 95% CI: (0.88, 0.98), p = 0.006) and
depression (adjusted OR = 0.92, 95% CI: (0.87, 0.98), p = 0.006). Conclusion: The prevalence of
stress, anxiety and depression among house officers in Kota Kinabalu, Sabah is high. Management
should look into the findings and understand the importance of addressing this problem as it may
affect patient care and safety, and the livelihood of house officers. Future studies identifying why
house officers are thinking of quitting service and why they do feel that they are being bullied may be
warranted.