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Displaying publications 41 - 60 of 97 in total

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Gambir, "Gambir Sarawak" and toad venom

Lim WJ, Yap AT, Mangudi M, Hu CY, Yeo CY, Eyo ZW, et al.

Drug Test Anal, 2017 Mar;9(3):491-499.
PMID: 27367276 DOI: 10.1002/dta.2034
Matched MeSH terms: Tannins/analysis
A tannin-based agent for coagulation and flocculation of municipal wastewater: Chemical composition, performance assessment compared to Polyaluminum chloride, and application in a pilot plant

Hameed YT, Idris A, Hussain SA, Abdullah N

J Environ Manage, 2016 Dec 15;184(Pt 3):494-503.
PMID: 27789092 DOI: 10.1016/j.jenvman.2016.10.033

Chemical composition and flocculation efficiency were investigated for a commercially produced tannin - based coagulant and flocculant (Tanfloc). The results of Fourier Transform Infrared Spectroscopy (FTIR) and Energy Dispersive Spectroscopy (EDX) confirmed what claimed about the chemical composition of Tanfloc. For moderate polluted municipal wastewater investigated in both jar test and pilot plant, Tanfloc showed high turbidity removal efficiency of approximately 90%, while removal efficiencies of BOD5 and COD were around 60%. According to floc size distribution, Tanfloc was able to show distinct performance compared to Polyaluminum chloride (PAC). While 90% of flocs produced by Tanfloc were smaller than 144 micron, they were smaller than 96 micron for PAC. Practically, zeta potential measurement showed the cationic nature of Tanfloc and suggested coincidence of charge neutralization and another flocculation mechanism (bridging or patch flocculation). Sludge Volumetric Index (SVI) measurements were in agreement with the numbers found in the literature, and they were less than 160 mL/g. Calcium cation as flocculation aid showed significant improvement of flocculation efficiency compared to other cations. Finally Tanfloc showed competing performance compared to PAC in terms of turbidity, BOD5 and COD removal, floc size and sludge characteristics.

Matched MeSH terms: Tannins/chemistry*
Sustainable approach in phlorotannin recovery from macroalgae

Chia SR, Show PL, Phang SM, Ling TC, Ong HC

J Biosci Bioeng, 2018 Aug;126(2):220-225.
PMID: 29673988 DOI: 10.1016/j.jbiosc.2018.02.015

In this present study, alcohol/salt liquid biphasic system was used to extract phlorotannin from brown macroalgae. Liquid biphasic system is a new green technology that integrated with various processes into one-step, by concentrating, separating and purifying the bioproduct in a unit operation. The solvent used is non-toxic and there is potential for solvent recovery which is beneficial to the environment. Phlorotannin is a bioactive compound that has gained much attention due to its health beneficial effect. Therefore, the isolation of phlorotannin is lucrative as it contains various biological activities that are capable to be utilised into food and pharmaceutical application. By using 2-propanol/ammonium sulphate system, the highest recovery of phlorotannin was 76.1% and 91.67% with purification factor of 2.49 and 1.59 from Padina australis and Sargassum binderi, respectively. A recycling study was performed and the salt phase of system was recycled where maximum salt recovery of 41.04% and 72.39% could be obtained from systems containing P. australis and S. binderi, respectively. Similar recovery of phlorotannin was observed after performing two cycles of the system, this concludes that the system has good recyclability and eco-friendly.

Matched MeSH terms: Tannins/isolation & purification*
Characterisation of galloylated cyanogenic glucosides and hydrolysable tannins from leaves of Phyllagathis rotundifolia by LC-ESI-MS/MS

Hooi Poay T, Sui Kiong L, Cheng Hock C

Phytochem Anal, 2011 Nov-Dec;22(6):516-25.
PMID: 21495106 DOI: 10.1002/pca.1312

Phyllagathis rotundifolia (Jack) Bl. (Melastomataceae) is a creeping herb found in Peninsular Malaysia and Sumatra. Traditionally, a decoction of the leaves is used in the treatment of malaria, fever and stomach ache.

Matched MeSH terms: Hydrolyzable Tannins/isolation & purification; Hydrolyzable Tannins/chemistry*
The insulin-sensitising properties of the ellagitannin geraniin and its metabolites from Nephelium lappaceum rind in 3T3-L1 cells

Perera A, Ton SH, Moorthy M, Palanisamy UD

Int J Food Sci Nutr, 2020 Dec;71(8):940-953.
PMID: 32319838 DOI: 10.1080/09637486.2020.1754348

In this study, the insulin-like and insulin sensitising effects of the ellagitannins geraniin, corilagin, ellagic acid, gallic acid and Nephelium lappaceum rind extract in 3T3-L1 adipocytes was investigated. It was observed that non-toxic concentrations of geraniin and its metabolites (0.2-20 μM) and N. lappaceum extract (0.2-20 μg/mL) exhibited insulin-like properties in the absence of insulin and insulin-sensitising properties in the presence of insulin particularly with regards to glucose uptake in 3T3-L1 adipocytes. The compounds were further able to promote adipocyte differentiation and may be involved in the inhibition of lipolysis in 3T3-L1 adipocytes in the presence of insulin. However further study into the molecular mechanisms of action of these compounds need to be carried out to better understand the potential of these compounds/extracts to act as therapeutic agents for hyperglycaemia associated with diabetes mellitus and obesity.

Matched MeSH terms: Hydrolyzable Tannins/pharmacology*; Hydrolyzable Tannins/chemistry
Fulltext Treatment of Palm Oil Refinery Effluent Using Tannin as a Polymeric Coagulant: Isotherm, Kinetics, and Thermodynamics Analyses

Mat Yasin NMF, Hossain MS, H P S AK, Zulkifli M, Al-Gheethi A, Asis AJ, et al.

Polymers (Basel), 2020 Oct 14;12(10).
PMID: 33066451 DOI: 10.3390/polym12102353

The refining of the crude palm oil (CPO) generates the palm oil refinery effluent (PORE). The presence of high contents of biochemical oxygen demand (BOD), chemical oxygen demand (COD), turbidity, and suspended solids (SS) in PORE encourages the determination of an effective treatment process to minimize the environmental pollution and preserve aquatic life. In the present study, a biodegradable natural polymer, namely tannin, was utilized as a coagulant to treat PORE. The coagulation experiment was conducted using a jar test apparatus. The tannin coagulation efficiency was evaluated based on the BOD, COD, turbidity, and SS removal from PORE by varying the tannin dose (50-300 mg/L), pH (pH 4-10), treatment time (15-90 min), and sedimentation time (15-90 min). It was found that the maximum removal of BOD, COD, turbidity, and SS was 97.62%, 88.89%, 93.01%, and 90.21%, respectively, at pH 6, a tannin dose of 200 mg/L, 60 min of coagulation time, and 60 min of sedimentation time. Analyses of isotherm models revealed that the Freundlich isotherm model was well fitted with the coagulation study. Kinetics studies show that the pseudo-second-order kinetics model was the well-fitted kinetics model for the BOD, COD, turbidity, and SS removal from PORE using tannin as a polymeric coagulant. The determination of thermodynamics parameters analyses revealed that BOD, COD, turbidity, and SS removal from PORE was spontaneous, exothermic, and chemical in nature. The finding of the present study shows that tannin as a natural polymeric coagulant would be utilized in PORE treatment to avoid toxic sludge generation.

Matched MeSH terms: Tannins
Surface-modified nanocrystalline cellulose from oil palm empty fruit bunch for effective binding of curcumin

Foo ML, Tan CR, Lim PD, Ooi CW, Tan KW, Chew IML

Int J Biol Macromol, 2019 Oct 01;138:1064-1071.
PMID: 31301392 DOI: 10.1016/j.ijbiomac.2019.07.035

Rod-shape particles have been a good drug carrier due to the long circulatory time, tumor accumulation and high cellular uptake in body. Acid-hydrolysed nanocrystalline cellulose (NCC) from empty fruit bunch exhibited a width of 13-30nm and a length of 150-360nm in rod-shape structure. NCC holds good potential as a bio-based drug carrier owing to its biodegradability and biocompatibility. Fourier-transform infrared spectroscopy results confirmed the binding of curcumin onto the NCC modified with tannic acid (TA) and decylamine (DA). TA-DA modification rendered NCC with a higher level of hydrophobicity, as evidenced by a substantial increase in contact angle from 45° to 73°. The modified NCC had the curcumin-binding efficiency in the range of 95-99%, which is at least twofold higher than the unmodified NCC at any curcumin concentration tested. This remarkable curcumin-binding effciency was comparable to that of commercialized NCC from wood-based origin. This work suggests NCC as a superior and sustainable drug carrier, while TA-DA modification is a promising approach to alter the surface property of NCC for an efficient binding of curcumin.

Matched MeSH terms: Tannins
Fulltext Development of Polyvinylidene Fluoride Membrane via Assembly of Tannic Acid and Polyvinylpyrrolidone for Filtration of Oil/Water Emulsion

Nawi NIM, Ong Amat S, Bilad MR, Nordin NAHM, Shamsuddin N, Prayogi S, et al.

Polymers (Basel), 2021 Mar 22;13(6).
PMID: 33810126 DOI: 10.3390/polym13060976

Wastewater containing oil/water emulsion has a serious ecological impact and threatens human health. The impact worsens as its volume increases. Oil/water emulsion needs to be treated before it is discharged or reused again for processing. A membrane-based process is considered attractive in effectively treating oil/water emulsion, but progress has been dampened by the membrane fouling issue. The objective of this study is to develop polyvinylidene fluoride (PVDF) membranes customized for oil/water emulsion separation by incorporating assembly of tannic acid (TA) and polyvinylpyrrolidone (PVP) in the polymer matrix. The results show that the assembly of TA/PVP complexation was achieved as observed from the change in colour during the phase inversion and as also proven from the characterization analyses. Incorporation of the TA/PVP assembly leads to enhanced surface hydrophilicity by lowering the contact angle from 82° to 47°. In situ assembly of the TA/PVP complex also leads to enhanced clean water permeability by a factor of four as a result of enhanced mean flow pore size from 0.2 to 0.9 µm. Owing to enhanced surface chemistry and structural advantages, the optimum hydrophilic PVDF/TA/PVP membrane poses permeability of 540.18 L/(m2 h bar) for oil/water emulsion filtration, three times higher than the pristine PVDF membrane used as the reference.

Matched MeSH terms: Tannins
Disruption of methicillin-resistant Staphylococcus aureus protein synthesis by tannins

Adnan SN, Ibrahim N, Yaacob WA

Germs, 2017 Dec;7(4):186-192.
PMID: 29264356 DOI: 10.18683/germs.2017.1125

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide public health threat, displaying multiple antibiotic resistance that causes morbidity and mortality. Management of multidrug-resistant (MDR) MRSA infections is extremely difficult due to their inherent resistance to currently used antibiotics. New antibiotics are needed to combat the emergence of antimicrobial resistance.
Methods: The in vitro effect of tannins was studied against MRSA reference strain (ATCC 43300) and MRSA clinical strains utilizing antimicrobial assays in conjunction with both scanning and transmission electron microscopy. To reveal the influence of tannins in MRSA protein synthesis disruption, we utilized next-generation sequencing (NGS) to provide further insight into the novel protein synthesis transcriptional response of MRSA exposed to these compounds.
Results: Tannins possessed both bacteriostatic and bactericidal activity with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of 0.78 and 1.56 mg/mL, respectively, against all tested MRSA. Scanning and transmission electron microscopy of MRSA treated with tannins showed decrease in cellular volume, indicating disruption of protein synthesis.
Conclusion: Analysis of a genome-wide transcriptional profile of the reference strain ATCC 43300 MRSA in response to tannins has led to the finding that tannins induced significant modulation in essential ribosome pathways, which caused a reduction in the translation processes that lead to inhibition of protein synthesis and obviation of bacterial growth. These findings highlight the potential of tannins as new promising anti-MRSA agents in clinical application such as body wash and topical cream or ointments.

Matched MeSH terms: Tannins
Fulltext What influences the use of local crude herbs among patients with chronic diseases? preliminary screening of phytochemicals

Deepa, R., Yin Yee, S., Afiqah Zulaikha R., Yun Li, C., Zhee Shah, C., Mei Ling, L., et al.

Malaysian Journal of Medicine and Health Sciences, 2019;15(102):51-51.
MyJurnal

Introduction: The use of crude herbs for well-being as well as curation and prevention of ailments is evident globally, including Malaysia. To understand the effectiveness and reliability, the presence of phytochemical compounds as the factor influencing the use of crude herbs shall be determined. This study was conducted to screen the presence of phytochemical compounds in the local crude herbs consumed by patients with chronic diseases. This is part of
a larger study, where a cross-sectional study was conducted and reported elsewhere. Methods: In total, 15 types of crude herbs were reported by the patients with chronic diseases attending government health clinic at Kampar, Perak. The herbs were extracted using hot and standard cold methods respectively. Results: All the 15 crude herbs’ hot and cold extracts revealed the presence of eight phytochemical compounds, namely, phenols, quinones, tannins, terpenoids, saponins, flavonoids, glycosides, and alkaloids at varying intensity. Saponins, alkaloids, and glycosides were present in all the crude herbs extracts. However, terpenoids, tannins, and phenols were absent in Orthosiphon stamineus, Clinacanthus nutans, and Pandanus amaryllifolius extracts respectively. However, the cold extracts exhibited a higher intensity of phytochemicals compared to hot extracts. The present study confirms the presence of
phytochemicals in the local crude herbs consumed by patients with chronic diseases. The screened phytochemicals are bioactive compounds that possess medicinal properties that may trigger the patients to treat their diseases’ underlying conditions. However, the use of prescribed medicine, particularly among aging patients must be taken into account while consuming crude herbs. Conclusion: The findings of this study indicate that structured-evidence based crude herbs use interventions for patients with chronic diseases is warranted.

Matched MeSH terms: Tannins
Fulltext CORRELATION BETWEEN TPC AND TFC WITH ANTIOXIDANT ACTIVITY OF Piper sarmentosum EXTRACT AND ITS FORMULATION FOR COSMETIC PURPOSES

WAN ASIAH WAN SUKAIRI, LAILI CHE ROSE, ASNUZILAWATI ASARI, RAZIFAH MOHD RAZALI

UMT Journal of Undergraduate Research, 2021;3(2):51-60.
MyJurnal

This study investigates the characteristics of an antioxidant cream made from the methanol extract of Piper sarmentosum leaves, which is locally known as the wild betel or pokok kadok in Malay. The secondary metabolites of the leaves were subjected to phytochemical tests to detect the presence of natural compounds. Antioxidant activity was described by its total phenolic content (TPC) and total flavonoid content (TFC), which was assessed by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. A phase diagram was constructed to find a possible region to formulate an antioxidant cream. In phytochemical screening, the methanolic extract showed positive presence of alkaloids, flavonoids, steroids, terpenoids and tannins. In quantitative analysis of antioxidative components, besides having significantly higher TFC content compared with quercetin (P

Matched MeSH terms: Tannins
Fulltext PHYTOCHEMICAL SCREENING AND EVALUATION OF THE ENZYMATIC ANTIOXIDANT ACTIVITIES OF SELECTED Mangifera spp. LEAVES (ANACARDIACEAE)

MISA HARSRINURI RAIHANI SAIRUN, NORHAYATI YUSUF, NORHAYATI YUSUF, NURUL HUDA ABDUL WAHAB, NURUL HUDA ABDUL WAHAB

UMT Journal of Undergraduate Research, 2020;2(4):1-8.
MyJurnal

A study was conducted on the chemical and biological properties of three different species of Mangifera i.e. Mangifera pajang, M. indica L., and M. kemanga leaves obtained from Pitas, Sabah. The aims of this study were to determine the presence of secondary metabolites as well as the antioxidative activities especially the catalase (CAT) and guiacol peroxidase specific activities (gPOD) in the leaves part of these three species. The extraction of these samples was carried out using three different polarities of solvents: hexane, ethyl acetate, and methanol. The total percentage of the crude extract of is 7.30% for M. pajang, 12.87% for M. indica and 7.98% for M. kemanga. Phytochemical screening was performed with various tests for each of the crude extracts. The results showed that these three species gave positive results for alkaloids, saponins, flavonoids, phenols, carbohydrates, phytosterols, and tannins metabolites. Based on the tests, CAT specific activities were significantly higher in the leaves of M. pajang with 4.35 ± 1.18 units/mg protein compared to M. indica L. and M. kemanga. The guaiacol peroxidase (gPOD) specific activities showed that M. indica L. has the highest activity with the value of 0.0047 ± 0.0004 units/mg protein.

Matched MeSH terms: Tannins
Fulltext An exotic fruit with high nutritional value: Kadsura coccinea fruit

Sun, J., Jiang, Y., Amin, I., Li, Z., Prasad, K.N., Duan, X., et al.

International Food Research Journal, 2011;18(2):651-657.
MyJurnal

This research was to determine nutritional composition, essential and toxic elemental content, and major phenolic acid with antioxidant activity in Kadsura coccinea fruit. The results indicated that Kadsura coccinea fruit exhibited the high contents of total protein, total fat, ash and essential elements such as calcium (Ca), ferrum (Fe) and phosphorus (P). The levels of four common toxic elements, i.e. cadmium (Cd), mercury (Hg), arsenic (As) and lead (Pb), were lower than legal limits. By high-performance liquid chromatography (HPLC) analysis, gallic acid was identified as major phenolic acid in peel and pulp tissues. Its contents were no significant difference in both tissues. In comparison with two commercial antioxidants, the major phenolic acid extracted from Kadsura coccinea exhibited stronger 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activity and reducing power. Kadsura coccinea fruit is a good source of nutrition and natural antioxidant. It is worthwhile to popularize this exotic fruit around the world.

Matched MeSH terms: Hydrolyzable Tannins
Fulltext Phytochemicals screening and total phenolic content of Malaysian Zea mays hair extracts

Solihah, M.A., Wan Rosli, W.I., Nurhanan, A.R.

International Food Research Journal, 2012;19(4):1533-1538.
MyJurnal

In the present study, Malaysian Zea mays hair extracts are screened for the occurrence of bioactive compounds. The results positively showed the present of flavonoids, saponin, tannins, phlobatannins, phenols, alkaloids and cardiac glycosides in both aqueous and methanolic extract of Zea mays hair. Terpenoid compounds however present only in the methanolic extract sample. In addition, the total phenolic content (TPC) in aqueous extract was significantly higher (42.71 + 0.87 µg/g of tannic acid equivalent (TAE)) compared to methanolic extract (40.38 + 1.10 µg/g of TAE). The findings suggested that phytochemicals present in Zea mays hair are potentially beneficial as therapeutic and antioxidative agents in pharmaceuticals, food and other related industries.

Matched MeSH terms: Tannins
Fulltext Effect of solvent extraction on antioxidant and antibacterial activities from Quercus infectoria (Manjakani)

Nur Syukriah, A.R., Liza, M.S., Harisun, Y., Fadzillah, A.A.M.

International Food Research Journal, 2014;21(3):1067-1073.
MyJurnal

Bioactive compounds from Quercus Infectoria (manjakani) were extracted with six different types of solvents: 100% methanol, ethanol, acetone, aqueous and 70% methanol and ethanol. High Performance liquid chromatography (HPLC) was used to identify and quantify the active compounds, namely gallic acid and tannic acid. Total phenolics content were determined by Folin-Ciocalteu while antioxidant and antibacterial activity were tested using DPPH free radicals scavenging and disc diffusion assay. The result revealed that aqueous extract contained the highest concentration of bioactive compounds compared to other types of solvents which are 51.14 mg/g sample and 1332.88 mg/g sample of gallic acid and tannic acid respectively.. The highest level of phenolic compound was found in 100% acetone extract (121 mg GAE/g). The results demonstrated that aqueous extract gives the highest antioxidant activity approximately 94.55% while acetone extract gives the largest inhibition zone for disc diffusion assay which is 19.00 mm respectively. The results revealed rich sources of gallic acid and tannic acid in Q. infectoria which might provide a novel source of these natural antioxidant and antibacterial activity.

Matched MeSH terms: Tannins
Fulltext Isolation of steroids from n-hexane extract of the leaves of Saurauia roxburghii

Ahmed, Y., Rahman, S., Akhtar, P., Islam, F., Rahman, M., Yaakob, Z.

International Food Research Journal, 2013;20(5):2939-2943.
MyJurnal

General phytochemical screening of the leaves of Saurauia roxburghii (Actinidiaceae) revealed the presence of alkaloids, flavonoids, glycosides, O-glycosides, terpenoids, carbohydrates, steroids, reducing sugar, tannins, phlobatannins and saponin are present in this plant whereas cardiac glycosides are absent. Two steroid compounds were isolated from the n-hexane extract of the leaves from S. roxburghii. Based on the spectral evidence IR, 1H-NMR and 13C-NMR, structures were determined to be stigmasterol (1) and β-sitosterol (2) This is the first report so far of occurrence and details spectroscopic description of these compounds from S. roxburghii.

Matched MeSH terms: Tannins
Fulltext Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum

BenSaad LA, Kim KH, Quah CC, Kim WR, Shahimi M

BMC Complement Altern Med, 2017 Jan 14;17(1):47.
PMID: 28088220 DOI: 10.1186/s12906-017-1555-0

Punica granatum (pomegranate), an edible fruit originating in the Middle East, has been used as a traditional medicine for treatment of pain and inflammatory conditions such as peptic ulcer. The numerous risks associated with nonsteroidal anti-inflammatory drugs (NSAIDs) for treatment of pain and inflammation give rise to using medicinal herbs as alternative therapies. This study aimed to evaluate the anti-inflammatory effect of isolated compounds from the ethyl acetate (EtOAc) fraction of P. granatum by determination of their inhibitory effects on lipopolysaccharide (LPS), stimulated nitric oxide (NO), prostaglandin E2 (PGE-2), interleukin-6 (IL-6) and cyclooxxgenase-2 (COX-2) release from RAW264.7 cells.

Matched MeSH terms: Hydrolyzable Tannins/analysis; Hydrolyzable Tannins/isolation & purification; Hydrolyzable Tannins/pharmacology*
Fulltext Analgesic activity, toxicity study and phytochemical screening of standardized Cinnomomum iners leaves methanolic extract

Mustaffa F, Indurkar J, Ismail S, Mordi MN, Ramanathan S, Mansor SM

Pharmacognosy Res, 2010 Mar;2(2):76-81.
PMID: 21808545 DOI: 10.4103/0974-8490.62952

Cinnomomum iners standardized leaves methanolic extract (CSLE) was subjected to analgesic, toxicity and phytochemical studies. The analgesic activity of CSLE was evaluated using formalin, hot plate and tail flick tests at doses of 100, 200 and 500 mg/kg. CSLE showed significant activity (P < 0.05) in the formalin model (late phase) on the rats at doses of 200 and 500 mg/kg. However, CSLE did not show activity in the hot plate and tail flick tests. The results obtained suggest that CSLE acts peripherally to relieve pain. For the toxicity study, CSLE was orally administered to the Swiss albino mice according to the Organization for Economic Co-Operation and Development (OECD) guideline 423. There was no lethality or toxic symptoms observed for all the tested doses throughout the 14-day period. Phytochemical screening of CSLE showed the presence of cardiac glycoside, flavonoid, polyphenol, saponin, sugar, tannin and terpenoid.

Matched MeSH terms: Tannins
Fulltext Antioxidant Properties and Cardioprotective Mechanism of Malaysian Propolis in Rats

Ahmed R, Tanvir EM, Hossen MS, Afroz R, Ahmmed I, Rumpa NE, et al.

Evid Based Complement Alternat Med, 2017;2017:5370545.
PMID: 28261310 DOI: 10.1155/2017/5370545

Propolis contains high concentrations of polyphenols, flavonoids, tannins, ascorbic acid, and reducing sugars and proteins. Malaysian Propolis (MP) has been reported to exhibit high 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and ferric reducing antioxidant power (FRAP) values. Herein, we report the antioxidant properties and cardioprotective properties of MP in isoproterenol- (ISO-) induced myocardial infarction in rats. Male Wistar rats (n = 32) were pretreated orally with an ethanol extract of MP (100 mg/kg/day) for 30 consecutive days. Subcutaneous injection of ISO (85 mg/kg in saline) for two consecutive days caused a significant increase in serum cardiac marker enzymes and cardiac troponin I levels and altered serum lipid profiles. In addition significantly increased lipid peroxides and decreased activities of cellular antioxidant defense enzymes were observed in the myocardium. However, pretreatment of ischemic rats with MP ameliorated the biochemical parameters, indicating the protective effect of MP against ISO-induced ischemia in rats. Histopathological findings obtained for the myocardium further confirmed the biochemical findings. It is concluded that MP exhibits cardioprotective activity against ISO-induced oxidative stress through its direct cytotoxic radical-scavenging activities. It is also plausible that MP contributed to endogenous antioxidant enzyme activity via inhibition of lipid peroxidation.

Matched MeSH terms: Tannins
Effects of condensed tannin fractions of different molecular weights from a Leucaena leucocephala hybrid on in vitro methane production and rumen fermentation

Saminathan M, Sieo CC, Abdullah N, Wong CM, Ho YW

J Sci Food Agric, 2015 Oct;95(13):2742-9.
PMID: 25418980 DOI: 10.1002/jsfa.7016

Molecular weights (MWs) and their chemical structures are the primary factors determining the influence of condensed tannins (CTs) on animal nutrition and methane (CH4 ) production in ruminants. In this study the MWs of five CT fractions from Leucaena leucocephala hybrid-Rendang (LLR) were determined and the CT fractions were investigated for their effects on CH4 production and rumen fermentation.

Matched MeSH terms: Tannins/chemistry*

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