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  1. Blood group in relation to oral Fordyce's granules and serum cholesterol level
    Diajil AR, Goodson ML
    J Oral Pathol Med, 2023 Jul;52(6):521-527.
    PMID: 37038041 DOI: 10.1111/jop.13432
    BACKGROUND: The ABO and Rh systems are the most commonly used blood-group systems used to classify blood group globally. A number of studies have shown that ABO blood groups may be associated with an increased serum cholesterol levels which in turn may be related to the presence of oral Fordyce spots or granules. Oral Fordyce's granules are ectopic sebaceous glands within the oral cavity and are visible through epithelium. The aim of this study was to assess the relationship between ABO and Rhesus blood groups and the presence of oral Fordyce's granules and serum cholesterols level by gender.

    METHODS: Following ethical approval and informed consent, 124 subjects were recruited into this cross-sectional study. Clinical oral examination assessed the number of Fordyce's granules and blood samples were collected to determine the serum cholesterol and ABO/Rh blood-group systems of individual subjects.

    RESULTS: Blood group AB+ showed the highest mean of oral Fordyce's granules number and serum cholesterol level but this was not statistically significant compared to other blood groups. Female subjects in this study who were AB+ were had significantly higher serum cholesterol levels than males.

    CONCLUSION: This study indicates an association between ABO blood group, serum cholesterol level and mean number of oral Fordyce's granules. A larger sample size in a future study is required to ascertain whether number of Fordyce's granules is an important measure of serum cholesterol, but the study does show that for AB+ individuals, females may have higher serum cholesterol than males.

    Matched MeSH terms: Sebaceous Glands/pathology
  2. Fulltext Leonine facies
    Low QJ, Cheo SW, Yap WYE
    Indian J Dermatol Venereol Leprol, 2020 2 19;87(4):589-591.
    PMID: 32068196 DOI: 10.4103/ijdvl.IJDVL_983_18
    Matched MeSH terms: Sebaceous Glands/pathology*
  3. Cutaneous adnexal neoplasms in biopsy specimens processed in the Department of Pathology, University of Malaya
    Jayalakshmi P, Looi LM
    Ann Acad Med Singap, 1996 Jul;25(4):522-5.
    PMID: 8893922
    A review of consecutive biopsies of adnexal tumours from 112 patients, received by the Department of Pathology, University of Malaya, over a 13-year period was undertaken. The age range of the patients was from 1 to 84 years, with a mean of 29.8 years. Thirty-three (32%) patients were under 20 years of age. There were 68 females with a male to female ratio of 1.0:1.5. In 105 cases (93.7%), the neoplasm was solitary. The tumour measured less than 2 cm in the largest dimension in 103 cases (92%). The common sites of occurrence were the head and neck region (59%) and extremities (25%). Neoplasms of hair follicle origin accounted for 63.4% (71 cases) of all lesions. Intra-tumour deposition of amyloid was noted in one of the 14 cases of trichoepithelioma.
    Matched MeSH terms: Sebaceous Glands/pathology
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