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Fulltext A case study of green building in Malaysia: Cost saving analysis

Soon, C.K., Zaini, Z., Mohd Ujang, A., Nagapan, S., Abdullah, A.H., Hasmori, M.F., et al.

Pertanika Journal of Science & Technology, 2017;25(105):191-196.
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The building sector consumes about forty percent of world energy, making energy efficiency in existing buildings an important issue. This study has been undertaken to investigate energy consumption of a building that has been redesigned to incorporate energy efficient features. It was found that the introduction of energy efficient features has helped to achieve savings up to 46% of the total spent on energy particularly based on electricity bills.
Fulltext Oral Lichen Planus in a Patient With a Thymoma: A Rare Finding

Gubod ER, Ramanathan A, Mohamad Zaini Z, Warnakulasuriya S

Cureus, 2021 Aug;13(8):e17376.
PMID: 34584786 DOI: 10.7759/cureus.17376

We present a rare case of ulcerative oral lichen planus that was associated with a thymoma discovered during the management phase, seven months after the initial diagnosis of oral lichen planus. Thymectomy was performed and investigations revealed pure red cell aplasia. Although rare, the association of a thymoma should be considered in recording the medical history of patients presenting with oral lichen planus.
Fulltext Periodontal disease as the initial oral manifestation of langerhans cell histiocytosis - a case report

Ahmad AR, Ismail SM, Zain RB, Mohamad Zaini Z

Ann Dent, 2009;16(1):31-36.
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Langerhans Cell Histiocytosis (LCH) refers to a group of lesions presenting with a spectrum of clinical. features but sharing similar histology. These lesions are rare and treatment has been quite variable with current treatment protocol recommended being dependent on whether it is a unifocal or multi focal bone disease or a multi focal multisystem disease. However, the clinical presentations of LCH are variable and the decision to place into the appropriate clinical types may sometimes be masked by the non-discovery of all the lesions. In the oral maxillofacial area, the clinical features of these lesions may further pose a problem by nondescript manifestations as dental/periodontal/oral mucosal disorders. These oral findings may sometimes lead to inappropriate choice of treatment and delay in the diagnosis of all the lesions involved. This paper describes one such case where LCH manifest itself as a periodontal disease thus leading to delay in identifying all the sites involved and consequently a delay in id~ntifying the appropriate clinical type.
Fulltext COVID-19 and dynamics of environmental awareness, sustainable consumption and social responsibility in Malaysia

Ali Q, Parveen S, Yaacob H, Zaini Z, Sarbini NA

Environ Sci Pollut Res Int, 2021 Oct;28(40):56199-56218.
PMID: 34050516 DOI: 10.1007/s11356-021-14612-z

Despite a profound evidence of the human unsustainable behaviours' impact on the environment, stark disparities prevail on this narrative especially in the context of the current epidemiological situation ushered by the COVID-19. The ongoing pandemic is a global public health concern due to its sagacious impacts on environmental sustainability, social responsibility and people's quality of life. This study primarily focuses on analysing the impact of COVID-19 (COV) on the environmental awareness (EA), sustainable consumption (SC) and social responsibility (SR). Additionally, we aspire to investigate the impact of demographics of generations and religion on the proposed nexus in this study. The data was collected from 700 participants of different age groups and religious backgrounds in Malaysia, and structural equation modelling (SEM) was used to analyse this data and test the hypotheses. The findings indicate that COVID-19 has a significantly positive impact on EA, SC and SR, and the generations and religiosity moderate the relationship between COVID-19 and its impact on sustainable behaviours. This study contributes to analyse the difference in the perception of EA, SC and SR among the people that eventually will stimulate the scientific reasoning among the governments, policymakers and scientists to develop a holistic framework to combat unprecedented event such as COVID-19 and ensure the authentication of sustainable environment and exceptional quality of life. The policymakers in Malaysia may use the findings of this study to inspect the social and environmental aspects of the people during the transformation events.
Accelerated implementation of teleconsultation services for the monitoring of oral potentially malignant disorders as a result of the COVID-19 pandemic

Rajendran S, Mohamad Zaini Z, Lim YZ, Kallarakkal TG, Ramanathan A, Chan SW, et al.

Oral Oncol, 2022 Feb 14;126:105730.
PMID: 35176655 DOI: 10.1016/j.oraloncology.2022.105730
High referral accuracy for oral cancers and oral potentially malignant disorders using telemedicine

Haron N, Rajendran S, Kallarakkal TG, Zain RB, Ramanathan A, Abraham MT, et al.

Oral Dis, 2023 Mar;29(2):380-389.
PMID: 33914993 DOI: 10.1111/odi.13892

OBJECTIVE: To evaluate the accuracy of MeMoSA®, a mobile phone application to review images of oral lesions in identifying oral cancers and oral potentially malignant disorders requiring referral.
SUBJECTS AND METHODS: A prospective study of 355 participants, including 280 with oral lesions/variants was conducted. Adults aged ≥18 treated at tertiary referral centres were included. Images of the oral cavity were taken using MeMoSA®. The identification of the presence of lesion/variant and referral decision made using MeMoSA® were compared to clinical oral examination, using kappa statistics for intra-rater agreement. Sensitivity, specificity, concordance and F1 score were computed. Images were reviewed by an off-site specialist and inter-rater agreement was evaluated. Images from sequential clinical visits were compared to evaluate observable changes in the lesions.
RESULTS: Kappa values comparing MeMoSA® with clinical oral examination in detecting a lesion and referral decision was 0.604 and 0.892, respectively. Sensitivity and specificity for referral decision were 94.0% and 95.5%. Concordance and F1 score were 94.9% and 93.3%, respectively. Inter-rater agreement for a referral decision was 0.825. Progression or regression of lesions were systematically documented using MeMoSA®.
CONCLUSION: Referral decisions made through MeMoSA® is highly comparable to clinical examination demonstrating it is a reliable telemedicine tool to facilitate the identification of high-risk lesions for early management.
Fulltext Pathogen genomic surveillance status among lower resource settings in Asia

Getchell M, Wulandari S, de Alwis R, Agoramurthy S, Khoo YK, Mak TM, et al.

Nat Microbiol, 2024 Oct;9(10):2738-2747.
PMID: 39317773 DOI: 10.1038/s41564-024-01809-4

Asia remains vulnerable to new and emerging infectious diseases. Understanding how to improve next generation sequencing (NGS) use in pathogen surveillance is an urgent priority for regional health security. Here we developed a pathogen genomic surveillance assessment framework to assess capacity in low-resource settings in South and Southeast Asia. Data collected between June 2022 and March 2023 from 42 institutions in 13 countries showed pathogen genomics capacity exists, but use is limited and under-resourced. All countries had NGS capacity and seven countries had strategic plans integrating pathogen genomics into wider surveillance efforts. Several pathogens were prioritized for human surveillance, but NGS application to environmental and human-animal interface surveillance was limited. Barriers to NGS implementation include reliance on external funding, supply chain challenges, trained personnel shortages and limited quality assurance mechanisms. Coordinated efforts are required to support national planning, address capacity gaps, enhance quality assurance and facilitate data sharing for decision making.