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  1. [Analysis of the development status of acupuncture and moxibustion in Malaysia]
    Shen JC, Rui X, Lynn ASS, Yang ZB
    Zhongguo Zhen Jiu, 2019 Aug 12;39(8):871-3.
    PMID: 31397134 DOI: 10.13703/j.0255-2930.2019.08.018
    The acupuncture and moxibustion of TCM was introduced into Malaysia since fourteenth century. After several centuries of precipitation and accumulation, acupuncture and moxibustion showed vigorous vitality in Malaysia. This article provides an overview of the development of acupuncture in Malaysia from a full-time education in acupuncture, association, policy support for acupuncture, clinical application and scientific research, etc. With the frequent exchanges between the traditional medical community in Malaysia and the Chinese medicine community in mainland China, the spread of acupuncture in Malaysia has been greatly promoted.
  2. Fulltext Effect of Huanglian Decoction on the Intestinal Microbiome in Stress Ulcer (SU) Mice
    Zhang Q, Guo JJ, Yau YM, Wang YJ, Cheng YB, Tuo X, et al.
    Evid Based Complement Alternat Med, 2021;2021:3087270.
    PMID: 34603467 DOI: 10.1155/2021/3087270
    Background: Stress ulcer (SU) is a serious gastrointestinal mucosal lesion under acute stress. Huanglian decoction is a famous traditional Chinese medicine prescription, which has been used to treat digestive system diseases for thousands of years. Many clinical cases have proved that Huanglian decoction has a good effect on SU. Some studies have shown that the intestinal bacteria will be changed accordingly when the gastrointestinal mucosa is damaged. However, there are few published reports on the effect of the intestinal microbiome with SU mice that were treated by Huanglian decoction. In this study, we investigated the effect of the fecal microbiome in mice with SU by the 16S rDNA sequencing technology.

    Methods: Male KM mice were induced by cold-restraint stress except for the normal control group and then treated by Huanglian decoction (Group HD) and Esomeprazole magnesium solution (Group ES) separately for 7 days. 16S rDNA sequencing technology analysis was applied to evaluate the changes of bacterial flora in mice feces. And, histopathological methods and molecular biological detection methods were also performed.

    Results: Huanglian decoction could help to repair the gastric mucosal injury and regulate the relative content of TNF-α and IL-1β. Moreover, Huanglian decoction could increase the relative abundance of intestinal probiotics in the intestine of mice with SU, especially in Verrucomicrobiae and Akkermansia.

    Conclusions: Huanglian decoction might effectively promote the repair of gastrointestinal mucosal injury and regulate the number and species of intestinal bacteria to maintain the stability of gastrointestinal microecology.

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