Augmented renal clearance (ARC) is a phenomenon where there is elevated
renal clearance and defined by creatinine clearance more than 130ml/min. ARC results
in changes of the pharmacokinetic and pharmacodynamic of antimicrobial therapy being
administered, which may result in its subtherapeutic dose. We evaluated the
prevalence, risk factors and outcome of ARC in critically ill patients with sepsis. (Copied from article).