MyMedR

MRI of optic tract lesions: review and correlation with visual field defects

Fadzli F, Ramli N, Ramli NM

Clin Radiol, 2013 Oct;68(10):e538-51.

PMID: 23932674 DOI: 10.1016/j.crad.2013.05.104

Visual field defects are a conglomerate of patterns of visual impairment derived from diseases affecting the optic nerve as it extends from the globe to the visual cortex. They are complex signs requiring perimetry or visual confrontation for delineation and are associated with diverse aetiologies. This review considers the chiasmatic and post-chiasmatic causes of visual disturbances, with an emphasis on magnetic resonance imaging (MRI) techniques. Newer MRI sequences are considered, such as diffusion-tensor imaging. MRI images are correlated with perimetric findings in order to demonstrate localization of lesions in the visual pathway. This may serve as a valuable reference tool to clinicians and radiologists in the early diagnostic process of differentiating causes of various visual field defects in daily practice.

Fulltext The boiling frog syndrome: A radiologist's perspective

Mohd Ramli N, Faridah Y

Biomed Imaging Interv J, 2010 Oct-Dec;6(4):e36.

PMID: 21611072 DOI: 10.2349/biij.6.4.e36

Fulltext Ptosis due to cavernous sinus syndrome as a rare presentation of advanced breast metastasis in a patient with delayed diagnosis

Khaw K, Ramli N, Rahmat K

Malays Fam Physician, 2012;7(1):31-3.

PMID: 25606243 MyJurnal

Complications of breast cancer metastasis may be the first manifestation of the disease. We report a rare case of left eye ptosis secondary to cavernous sinus syndrome in a 34-year-old lady due to refusal of proper medical treatment for metastatic breast cancer. The delay in seeking medical treatment was attributed to her use of Traditional Chinese Medicine (TCM).

Unilateral moyamoya disease with co-existing arteriovenous malformation

Nawawi O, Sinnasamy M, Ramli N

Br J Radiol, 2006 Jul;79(943):e12-5.

PMID: 16823046

A case of an intracerebral bleed in a young man with a rare combination of arteriovenous malformation (AVM) and unilateral moyamoya disease is presented. The location of the bleed in the left basal ganglia corresponded to the area supplied by the basal moyamoya vessels. The AVM which received supply from collateral moyamoya vessels as well as normal cerebral arteries was located in the ipsilateral parieto-occipital region posterior to the basal ganglia bleed. This is the first reported cerebral AVM co-existing with a unilateral moyamoya disease in the English literature. Unusual features of the case such as the unilaterality of the angiographic abnormalities, their coexistence and hypotheses as to their development are discussed.

Differentiating multiple-system atrophy from Parkinson's disease

Ramli N, Nair SR, Ramli NM, Lim SY

Clin Radiol, 2015 May;70(5):555-64.

PMID: 25752581 DOI: 10.1016/j.crad.2015.01.005

The purpose of this review is to illustrate the differentiating features of multiple-system atrophy from Parkinson's disease at MRI. The various MRI sequences helpful in the differentiation will be discussed, including newer methods, such as diffusion tensor imaging, MR spectroscopy, and nuclear imaging.

Glaucoma severity affects diffusion tensor imaging (DTI) parameters of the optic nerve and optic radiation

Sidek S, Ramli N, Rahmat K, Ramli NM, Abdulrahman F, Tan LK

Eur J Radiol, 2014 Aug;83(8):1437-41.

PMID: 24908588 DOI: 10.1016/j.ejrad.2014.05.014

To evaluate whether MR diffusion tensor imaging (DTI) of the optic nerve and optic radiation in glaucoma patients provides parameters to discriminate between mild and severe glaucoma and to determine whether DTI derived indices correlate with retinal nerve fibre layer (RNFL) thickness.

Fulltext Post viral acute multifocal posterior placoid pigment epithiopathy in a teenage child

Nga AD, Ramli N, Mimiwati Z

Med J Malaysia, 2009 Jun;64(2):176-8.

PMID: 20058585 MyJurnal

We report a rare case of a young boy presenting with bilateral blurring of vision following a viral like illness. Fundus examination revealed multiple pale cream-coloured lesions scattered across the posterior pole of both eyes. Fundus fluorescein angiography showed characteristic features of early hypofluorescence and late hyperfluorescence, further confirming the diagnosis of acute posterior placoid pigment epitheliopathy (AMPPPE). He was treated with topical steroids for the accompanying mild anterior uveitis. He had a prompt visual recovery with no adverse sequelae.

The past, present and future of imaging in multiple sclerosis

Ramli N, Rahmat K, Azmi K, Chong HT

J Clin Neurosci, 2010 Apr;17(4):422-7.

PMID: 20167498 DOI: 10.1016/j.jocn.2009.09.014

Despite technological advances in imaging, multiple sclerosis (MS) remains a clinical diagnosis that is supported, but not replaced, by laboratory or imaging findings. However, imaging is essential in the current diagnostic criteria of MS, for prediction of the likelihood of MS for patients with clinically isolated syndromes, correlation with lesion pathology and assessment of treatment outcome. This article gives an overview of imaging in MS with particular emphasis on the role of MRI in various diagnostic imaging criteria. Novel imaging for MS using 3 Tesla field strengths, magnetization transfer imaging, diffusion tensor imaging, magnetic resonance spectroscopy and cell-specific contrast will be reviewed.

Assessment of infectiousness of male Malaysian blood donors

So-Har T, Gladys LC, Ramli N

Vox Sang, 1983;45(5):389-91.

PMID: 6636661

HBeAg and anti-HBe were determined in the blood of 189 male blood donors. The incidence of HBsAg was 6.9% while that for HBeAg and anti-HBe was 1.6 and 18%, respectively. Of the 13 samples positive for HBsAg, two (15.4%) were positive for HBe while six (46.2%) were positive for anti-HBe. One specimen was negative for HBsAg but was positive for HBeAg and anti-HBe. The observations are discussed.

Fulltext Length-weight relationship of six fish species from Sepang Besar River Estuary, Malaysia

Ya, N. A., Singh, H. R., Samat, A., Mohd Rashid, H. N., Ramli, N. H., Makhtar, N., et al.

Journal of Advanced Research in Applied Sciences and Engineering Technology, 2015;1(1):27-35.

MyJurnal

Length-weight relationship (LWR) of six fish species from the Sepang Besar River estuary,
Peninsular Malaysia were analyzes. A total of 594 individuals belonging to six species namely Arius
sagor, Photopectoralis bindus, Plotosus lineatus, Toxotes chatareus, Toxotes jaculatrix, and Thryssa
dussumieri collected from April 2014 to February 2015 were measured and weighed. Among them, four
species showed positive allometric growth and the other two species showed negative allometric
growth. The exponent b value of LWR ranged between 2.94 (Toxotes chatareus) and 3.50
(Photopectoralis bindus). This outcome of the present study has contributed to the knowledge of basic
information on the length–weight relationship of six most abundant species in Sepang Besar River
estuary which is important for future ecological studies and assist in fishery management. Copyright
© 2015 Penerbit Akademia Baru - All rights reserved.

A study on the age at menopause and menopausal symptoms among Malaysian women

Arshat H, Tey NP, Ramli N

Malays J Reprod Health, 1989 Jun;7(1):1-9.

PMID: 12342395

Fulltext Bilateral internal carotid artery hypotrophy in malignant osteopetrosis

Ramli N, Rahmat K, Tan GP

Singapore Med J, 2008 Jul;49(7):e175-7.

PMID: 18695851

Malignant osteopetrosis is associated with petrous carotid canal and internal carotid artery stenosis in the skull base. We present a four-year-old boy with malignant osteopetrosis who developed right frontal lobe infarction as a result of bilateral internal carotid artery hypotrophy.

Fulltext A child with atypical teratoid/rhabdoid tumour of the posterior cranial fossa

Rahmat K, Kua CH, Ramli N

Singapore Med J, 2008 Dec;49(12):e365-8.

PMID: 19122937

Primary central nervous system (CNS) atypical teratoid/rhabdoid tumours (ATRT) are highly malignant neoplasms which usually present in infancy or early childhood. Although ATRT may arise anywhere within the CNS, the majority (approximately two-thirds) arise in the cerebellum or posterior fossa, and the remainder in the cerebrum. We described the imaging characteristics of CNS ATRT in the posterior cranial fossa of a 14-month-old boy.

Fulltext Extrapulmonary sarcoidosis: unusual cause of epiphora

Ramlee N, Ramli N, Liza-Sharmini AT

Singapore Med J, 2007 Jun;48(6):e168-70.

PMID: 17538739

Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology mainly affecting African-Americans, Scandinavians, and the Irish. However, individuals of other races and ethnicities are still not immune. The clinical presentations vary widely with most patients having some respiratory problems. Though extrapulmonary sarcoidosis is no longer rare, sarcoidosis involving the lacrimal sac is an infrequently-reported problem. We present a case of sarcoidosis involving the lacrimal sac in a 42-year-old Malay woman who presented with epiphora. She was successfully treated with steroids and dacryocystorhinostomy. There was no evidence of systemic involvement. It is suggested that in an unusual presentation of sarcoidosis, a thorough search should be made for localisation of other sites, lungs in particular, even in the absence of respiratory complaints.

Fulltext Chest imaging features of patients afflicted with Influenza A (H1N1) in a Malaysian tertiary referral centre

Bux S, Mohd Ramli N, Ahmad Sarji S, Kamarulzaman A

Biomed Imaging Interv J, 2010 Oct-Dec;6(4):e35.

PMID: 21611071 MyJurnal DOI: 10.2349/biij.6.4.e35

This is a retrospective descriptive study of the chest imaging findings of 118 patients with confirmed A(H1N1) in a tertiary referral centre. About 42% of the patients had positive initial chest radiographic (CXR) findings. The common findings were bi-basal air-space opacities and perihilar reticular and alveolar infiltrates. In select cases, high-resolution computed tomography (CT) imaging showed ground-glass change with some widespread reticular changes and atelectasis.

Pleomorphic adenoma in the palpebral lobe of the lacrimal gland misdiagnosed as chalazion

Ramlee N, Ramli N, Tajudin LS

Orbit, 2007 Jun;26(2):137-9.

PMID: 17613864

We reported a case of pleomorphic adenoma of the lacrimal gland involving the palpebral lobe in young teenage girl of Asian origin. The presentation at young age group is rare, which initially misdiagnosed as a large chalazion. The benign tumor with its intact pseudocapsule was removed through lateral orbitotomy together with the suspicious looking orbital lobe.

A viable secondary intra-abdominal pregnancy resulting from rupture of uterine scar: role of MRI

Teng HC, Kumar G, Ramli NM

Br J Radiol, 2007 Jul;80(955):e134-6.

PMID: 17704308

Pre-natal diagnosis of intra-abdominal pregnancy is difficult. Ultrasound has been the frontline modality to date; however, it gives a diagnostic error of 50-90% and its use is disappointing. In recent years, MRI has emerged as an appealing imaging modality. With its good soft tissue contrast and non-ionizing property, it acts as a means of definitive non-invasive assessment before surgical intervention when ultrasound is inconclusive.

Low nocturnal ocular perfusion pressure as a risk factor for normal tension glaucoma

Ramli N, Nurull BS, Hairi NN, Mimiwati Z

Prev Med, 2013;57 Suppl:S47-9.

PMID: 23352960 DOI: 10.1016/j.ypmed.2013.01.007

In the absence of raised intraocular pressure (IOP), haemodynamic parameters have been implicated in the development of normal tension glaucoma (NTG). The purpose of this study is to compare 24-hour IOP and haemodynamic parameters in NTG patients and non-glaucoma patients.

Post-traumatic arachnoiditis: an unusual cause of Brown-Sequard syndrome

Ramli N, Merican AM, Lim A, Kumar G

Eur Radiol, 2001;11(10):2011-4.

PMID: 11702136

Brown-Sequard syndrome (BSS) is a unilateral cord injury characterised by an ipsilateral motor deficit with contralateral pain and temperature hypoaesthesia. Although there are a variety of causes, the majority of cases are generally of neoplastic origin or are traumatic in origin. We describe a rare cause of Brown-Sequard syndrome as a result of post-traumatic arachnoiditis. Magnetic resonance imaging with the use of thin-slice high-resolution constructive interference in steady state (CISS) and T2-weighted spin-echo sequence were used to demonstrate the cause and appearance of the lesion in the spinal canal and was useful in the assessment and management of the patient. This case illustrates the usefulness of the CISS sequence in MRI for elucidating arachnoiditis.

Comparison of cataract surgery refractive outcomes in a tertiary hospital and an outreach cataract service centre

Soundarajan K, Nor Fariza N, Ramli N, Salowi MA

Med J Malaysia, 2021 Jan;76(1):35-40.

PMID: 33510106

OBJECTIVE: The aim of this study was to compare the postoperative refractive outcome after cataract surgery between a hospital-based and an outreach-based cataract service centre.

METHODS: This study was conducted at the Hospital Selayang (HS), Selangor, Malaysia, a tertiary referral centre and an outreach-based cataract service centre (Pusat Pembedahan Katarak MAIWP, PPKM). Data was sourced from the Cataract Surgery Registry (CSR) in the National Eye Database (NED).

RESULTS: A total of 2318 surgeries were analysed. PPKM achieved postoperative refraction outcome within ±1.0D in 94.3% of cases compared with 88.4% in Selayang Hospital. Mean absolute prediction error was also better in PPKM (0.39±0.27D vs. 0.33±0.24D, p<0.001). Multivariate analysis showed that the tertiary hospital, persons of Chinese ethnicity, history of uveitis, previous history of ocular surgery and intraoperative complications as significant independent predictive factors for poor refractive outcomes.

CONCLUSION: The outreach-based cataract service centre, which incorporates streamlined process designs and workflows, achieved superior refractive outcomes within ±1 dioptre after cataract surgery compared to a tertiary hospital.

Displaying publications 1 - 20 of 167 in total