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Histopathological Study of the Lungs of Mice Receiving Human Secretory IgA and Challenged with Mycobacterium tuberculosis

Alvarez N 1 , Infante JF 1 , Borrero R 1 , Mata D 2 , Payan JB 2 , Hossain MM 3 Show all authors , Mohd Nor N 3 , Sarmiento ME 1 , Hernandez-Pando R 2 , Acosta A 1

Affiliations 

  • 1 Department of Molecular Biology, Finlay Institute, Center of Research-Production of Vaccines, Ave. 27 No. 19805, La Lisa, Ciudad de la Habana, Cuba. AP. 16017, CP11600
  • 2 Experimental Pathology Section, Department of Pathology, National Institute of Medical Sciences and Nutrition "Salvador Zubirán", Mexico
  • 3 School of Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
Malays J Med Sci, 2014 May;21(3):31-7.
PMID: 25246833 MyJurnal

Abstract

Humoral and cellular immune responses are associated with protection against extracellular and intracellular pathogens, respectively. In the present study, we evaluated the effect of receiving human secretory immunoglobulin A (hsIgA) on the histopathology of the lungs of mice challenged with virulent Mycobacterium tuberculosis.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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