Recent Developments of Reverse Micellar Techniques for Lysozyme, Bovine Serum Albumin, and Bromelain Extraction

Chia SR 1 , Tang MSY 2 , Chow YH 3 , Ooi CW 4 , Rambabu K 5 , Zhu L 6 Show all authors , Show PL 7

Affiliations 

  • 1 Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, The University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Malaysia
  • 2 Faculty of Science, Institute of Biological Sciences, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • 3 School of Engineering, Taylor's University, Lakeside Campus, Jalan Taylor's, 47500, Subang Jaya, Selangor, Malaysia
  • 4 Chemical Engineering, School of Engineering, Monash University, 46150, Bandar Sunway, Selangor, Malaysia
  • 5 Department of Chemical Engineering, School of Civil and Chemical Engineering, Vellore Institute of Technology University, Vellore, 632014, India
  • 6 School of Resource and Environmental Sciences, Wuhan University, 129 Luoyu Road, Wuhan, 430079, People's Republic of China
  • 7 Department of Chemical and Environmental Engineering, Faculty of Science and Engineering, The University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Malaysia. [email protected]
Mol Biotechnol, 2019 Oct;61(10):715-724.
PMID: 31350687 DOI: 10.1007/s12033-019-00200-7

Abstract

Biomolecules produced by living organisms can perform vast array of functions and play an important role in the cell. Important biomolecules such as lysozyme, bovine serum albumin (BSA), and bromelain are often studied by researchers due to their beneficial properties. The application of reverse micelles is an effective tool for protein separation from their sources due to the special system structure. Mechanisms of transferring biomolecules and factors that influence the extraction of biomolecules are reviewed in this paper. The enhancement of biomolecule extraction could be achieved depending on the properties of reverse micelles. This paper provides an overall review on lysozyme, BSA, and bromelain extraction by reverse micelle for various applications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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