Introduction: Sleep, much like eating, is a pivotal part of life. The
mechanisms of sleep are only partly clear and are the subject of future
intense research. Scientific evidence behind sleep-promoting supplements
such as alpha-s1-casein tryptic hydrolysate is briefly described. These are
reviewed using data from clinical trials. Although there are clear
physiological connections behind these effects, the clinical relevance has to be
studied further. This review seeks to serve as a reference for future clinical
trials to promote sleep.
Methods: Potentially eligible papers were screened at
the title and abstract level; of which full text papers on human-based trial
were retrieved. Papers were also identified from screening of reference lists.
Results: A literature search was undertaken between Year 2005 to Year 2016
using database Google Scholar. Search terms were “Effects of alpha-s1-
casein tryptic hydrolysate”. A total of seven studies were reviewed and
summarized.
Conclusion: Randomized controlled trial in human being is
warranted to unearth the potential benefits of αs1-casein tryptic hydrolysate
for Malaysian adults.